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Extract from the Register of European Patents

EP About this file: EP1226136

EP1226136 - TYROSINE KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.11.2005
Database last updated on 28.09.2024
Most recent event   Tooltip04.11.2005No opposition filed within time limitpublished on 21.12.2005  [2005/51]
Applicant(s)For all designated states
Merck & Co., Inc.
126 East Lincoln Avenue
Rahway, New Jersey 07065-0907 / US
[N/P]
Former [2002/31]For all designated states
Merck & Co., Inc.
126 East Lincoln Avenue
Rahway, New Jersey 07065-0907 / US
Inventor(s)01 / ARRINGTON, Kenneth, L.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
02 / BILODEAU, Mark, T.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
03 / FRALEY, Mark, E.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
04 / HARTMAN, George, D.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
05 / HOFFMAN, William, F.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
06 / HUNGATE, Randall, W.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
07 / KIM, Yuntae
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
 [2002/31]
Representative(s)Horgan, James Michael Frederic, et al
Merck & Co., Inc.
European Patent Department
Terlings Park
Eastwick Road, Harlow
Essex CM20 2QR / GB
[N/P]
Former [2004/27]Horgan, James Michael Frederic, et al
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Former [2002/31]Thompson, John Dr.
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Application number, filing date00978230.116.10.2000
[2002/31]
WO2000US28625
Priority number, dateUS19990160356P19.10.1999         Original published format: US 160356 P
[2002/31]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0129025
Date:26.04.2001
Language:EN
[2001/17]
Type: A2 Application without search report 
No.:EP1226136
Date:31.07.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 26.04.2001 takes the place of the publication of the European patent application.
[2002/31]
Type: B1 Patent specification 
No.:EP1226136
Date:29.12.2004
Language:EN
[2004/53]
Search report(s)International search report - published on:EP01.11.2001
ClassificationIPC:C07D401/00
[2002/31]
CPC:
C07D413/14 (EP,US); C07D409/14 (EP,KR,US); A61K31/495 (EP,US);
A61K45/06 (EP,US); A61P17/00 (EP); A61P17/02 (EP);
A61P17/06 (EP); A61P19/00 (EP); A61P19/02 (EP);
A61P19/08 (EP); A61P19/10 (EP); A61P25/00 (EP);
A61P25/16 (EP); A61P25/28 (EP); A61P27/00 (EP);
A61P27/02 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P31/00 (EP); A61P35/00 (EP); A61P37/00 (EP);
A61P43/00 (EP); A61P7/12 (EP); A61P9/00 (EP);
A61P9/10 (EP); C07D401/04 (EP,US); C07D401/06 (KR);
C07D401/14 (EP,KR,US); C07D405/14 (EP,US); C07D417/14 (EP,KR,US) (-)
C-Set:
A61K31/495, A61K2300/00 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/31]
Extension statesAL21.05.2002
LT21.05.2002
LV21.05.2002
MK21.05.2002
RO21.05.2002
SI21.05.2002
TitleGerman:TYROSIN KINASEINHIBITOREN[2002/31]
English:TYROSINE KINASE INHIBITORS[2002/31]
French:INHIBITEURS DE TYROSINE KINASES[2002/31]
Entry into regional phase21.05.2002National basic fee paid 
21.05.2002Designation fee(s) paid 
21.05.2002Examination fee paid 
Examination procedure11.05.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
15.04.2002Amendment by applicant (claims and/or description)
21.05.2002Examination requested  [2002/31]
01.10.2002Despatch of a communication from the examining division (Time limit: M06)
26.03.2003Reply to a communication from the examining division
23.05.2003Despatch of a communication from the examining division (Time limit: M02)
24.06.2003Reply to a communication from the examining division
16.03.2004Communication of intention to grant the patent
27.09.2004Fee for grant paid
27.09.2004Fee for publishing/printing paid
Opposition(s)30.09.2005No opposition filed within time limit [2005/51]
Fees paidRenewal fee
07.10.2002Renewal fee patent year 03
06.10.2003Renewal fee patent year 04
06.10.2004Renewal fee patent year 05
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Cited inInternational search[A]WO9220642  (RHONE POULENC RORER INT [US]) [A] 1,8* page 42 *;
 [A]WO9706144  (DU PONT MERCK PHARMA [US], et al) [A] 1,8 * pages 57-72; table 3 *;
 [X]  - MARTIN P. MAGUIRE, KIMBERLY R SHEETS, KAREN MCVETY AT AL., "A new series of PDGF receptor tyrosine kinase inhibitors: 3-substituted quinoline derivatives", J.MED.CHEM., (1994), vol. 37, pages 2129 - 2137, XP002164235 [X] 1-8,20,21,23-25 * page 2130, column R - page 2133, column L; example 2G *

DOI:   http://dx.doi.org/10.1021/jm00045a004
 [A]  - LAURENT F.HENNEQUIN,ANDREW P.THOMAS, CRAIG JOHNSTONE, ET AL., "Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors", J.MED.CHEM., (1999), vol. 42, pages 535369 - 5389, XP002164236 [A] 1,8 * page 5371, column R - page 5378, column L *

DOI:   http://dx.doi.org/10.1021/jm990345w
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.