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EP1897867 - COMPOUNDS USED FOR INTERRUPTING REUPTAKE OF 5-HYDROXYTRYPTAMINE AND NOREPINEPHRINE OR TREATING DISEASES SUCH AS DEPRESSION [Right-click to bookmark this link]
Former [2008/11]COMPOUNDS, PREPARATION PROCESS, AND USES THEREOF USED FOR INTERRUPTING REUPTAKE OF 5-HYDROXYTRYPTAMINE AND NOREPINEPHRINE OR TREATING DISEASES SUCH AS DEPRESSION ET AL.
[2016/36]
StatusNo opposition filed within time limit
Status updated on  22.12.2017
Database last updated on 08.04.2026
FormerThe patent has been granted
Status updated on  13.01.2017
FormerGrant of patent is intended
Status updated on  04.01.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
SHANDONG LUYE PHARMACEUTICAL CO., LTD.
No. 15 Chuangye Road
Yantai High-Tech Zone
Shangdong Province 264670 / CN
For all designated states
Li, Youxin
No.402 Hua Yuan Yi Cun Liu Dong Tianping Rd., Tianyuan Dist.
Zhuzhou, Hunan 412000 / CN
[2017/09]
Former [2008/11]For all designated states
SHANDONG LUYE PHARMACEUTICAL CO., LTD.
No. 9 Baoyuan Road Laishan District
Yantai, Shandong 264003 / CN
For all designated states
Li, Youxin
No.402 Hua Yuan Yi Cun Liu Dong Tianping Rd., Tianyuan Dist.
Zhuzhou, Hunan 412000 / CN
Inventor(s)01 / ZHANG, Luping
402, Building 6, Hua Yuan Yi Cun, Tianping Road
Tianyuan District, Zhuzhou, Hunan 412000 / CN
 [2017/31]
Former [2008/11]01 / ZANG, Luping
402, Building 6, Hua Yuan Yi Cun, Tianping Road
Tianyuan District, Zhuzhou, Hunan 412000 / CN
Representative(s)Ipsilon
11 rue Saint-Georges
75009 Paris / FR
[N/P]
Former [2017/07]Nony
11 rue Saint-Georges
75009 Paris / FR
Former [2008/11]Le Coupanec, Pascale A.M.P.
Nony & Associés, 3 rue de Penthièvre
75008 Paris / FR
Application number, filing date06752979.216.06.2006
[2008/11]
WO2006CN01370
Priority number, dateCN2005107751017.06.2005         Original published format: CN200510077510
CN2006107330807.04.2006         Original published format: CN200610073308
[2008/11]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2006133652
Date:21.12.2006
Language:ZH
[2006/51]
Type: A1 Application with search report 
No.:EP1897867
Date:12.03.2008
Language:EN
[2008/11]
Type: B1 Patent specification 
No.:EP1897867
Date:15.02.2017
Language:EN
[2017/07]
Type: B8 Corrected title page of specification 
No.:EP1897867
Date:23.08.2017
[2017/34]
Search report(s)International search report - published on:CN21.12.2006
(Supplementary) European search report - dispatched on:EP31.08.2010
ClassificationIPC:C07C271/44, C07C219/28, A61K31/222, A61P25/00
[2016/36]
CPC:
C07C219/28 (EP,KR,US); C07C215/64 (KR); A61P25/00 (EP);
A61P25/04 (EP); A61P25/24 (EP); A61P43/00 (EP);
C07C219/24 (KR); C07C271/44 (EP,US) (-)
Former IPC [2008/11]C07C215/42, C07C217/60, C07C219/24, A61K31/222, A61P25/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/07]
Former [2008/11]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERBINDUNGEN ZUR UNTERBRECHUNG DER WIEDERAUFNAHME VON 5-HYDROXYTRYPTAMIN UND NOREPINEPHRIN ODER ZUR BEHANDLUNG VON KRANKHEITEN WIE DEPRESSION[2016/36]
English:COMPOUNDS USED FOR INTERRUPTING REUPTAKE OF 5-HYDROXYTRYPTAMINE AND NOREPINEPHRINE OR TREATING DISEASES SUCH AS DEPRESSION[2016/36]
French:COMPOSÉS POUR INTERROMPRE LE RECAPTAGE DE LA 5-HYDROXYTRYPTAMINE ET DE LA NORÉPINÉPHRINE OU LE TRAITEMENT DE PATHOLOGIES TELLES QUE LA DÉPRESSION[2016/36]
Former [2008/11]VERBINDUNGEN, HERSTELLUNGSVERFAHREN UND ANWENDUNGEN DAVON ZUR UNTERBRECHUNG DER WIEDERAUFNAHME VON 5-HYDROXYTRYPTAMIN UND NOREPINEPHRIN ODER ZUR BEHANDLUNG VON KRANKHEITEN WIE DEPRESSION U.A.
Former [2008/11]COMPOUNDS, PREPARATION PROCESS, AND USES THEREOF USED FOR INTERRUPTING REUPTAKE OF 5-HYDROXYTRYPTAMINE AND NOREPINEPHRINE OR TREATING DISEASES SUCH AS DEPRESSION ET AL.
Former [2008/11]COMPOSÉS, PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION POUR INTERROMPRE LE RECAPTAGE DE LA 5-HYDROXYTRYPTAMINE ET DE LA NORÉPINÉPHRINE OU LE TRAITEMENT DE PATHOLOGIES TELLES QUE LA DÉPRESSION ET AL.
Entry into regional phase17.01.2008Translation filed 
17.01.2008National basic fee paid 
17.01.2008Search fee paid 
17.01.2008Designation fee(s) paid 
17.01.2008Examination fee paid 
Examination procedure15.01.2007Request for preliminary examination filed
International Preliminary Examining Authority: CN
17.01.2008Examination requested  [2008/11]
06.09.2011Despatch of a communication from the examining division (Time limit: M04)
28.12.2011Reply to a communication from the examining division
05.06.2014Despatch of a communication from the examining division (Time limit: M04)
26.08.2014Reply to a communication from the examining division
30.10.2015Despatch of a communication from the examining division (Time limit: M04)
22.12.2015Reply to a communication from the examining division
07.09.2016Communication of intention to grant the patent
26.12.2016Fee for grant paid
26.12.2016Fee for publishing/printing paid
26.12.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.09.2011
Opposition(s)16.11.2017No opposition filed within time limit [2018/04]
Fees paidRenewal fee
17.01.2008Renewal fee patent year 03
27.05.2009Renewal fee patent year 04
11.06.2010Renewal fee patent year 05
13.06.2011Renewal fee patent year 06
14.06.2012Renewal fee patent year 07
10.06.2013Renewal fee patent year 08
31.03.2014Renewal fee patent year 09
10.06.2015Renewal fee patent year 10
10.06.2016Renewal fee patent year 11
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Lapses during opposition  TooltipHU16.06.2006
AT15.02.2017
CY15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SI15.02.2017
SK15.02.2017
BG15.05.2017
IS15.06.2017
LU16.06.2017
[2020/33]
Former [2019/46]HU16.06.2006
AT15.02.2017
CY15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SI15.02.2017
SK15.02.2017
BG15.05.2017
LU16.06.2017
Former [2019/31]HU16.06.2006
AT15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SI15.02.2017
SK15.02.2017
BG15.05.2017
LU16.06.2017
Former [2018/21]AT15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SI15.02.2017
SK15.02.2017
BG15.05.2017
LU16.06.2017
Former [2018/14]AT15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SI15.02.2017
SK15.02.2017
BG15.05.2017
Former [2018/11]AT15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
MC15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SK15.02.2017
BG15.05.2017
Former [2017/49]AT15.02.2017
CZ15.02.2017
EE15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
NL15.02.2017
RO15.02.2017
SE15.02.2017
SK15.02.2017
BG15.05.2017
Former [2017/48]AT15.02.2017
CZ15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
NL15.02.2017
SE15.02.2017
BG15.05.2017
Former [2017/41]AT15.02.2017
FI15.02.2017
LT15.02.2017
LV15.02.2017
NL15.02.2017
SE15.02.2017
BG15.05.2017
Documents cited:Search[A] US2004181093  (KIM KEUN-SIK et al.) [A] 1-6 * claim 1 *
 [A]   YARDLEY J P ET AL: "2-PHENYL-2-(1-HYDROXYCYCLOALKYL)ETHYLAMINE DERIVATIVES: SYNTHESIS AND ANTIDEPRESSANT ACTIVITY", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US LNKD- DOI:10.1021/JM00172A035, vol. 33, 1 January 1990 (1990-01-01), pages 2899 - 2905, XP000891765, ISSN: 0022-2623 [A] 1-10 * Scheme II; steps e,f;;; compounds VI,2 *

DOI:   http://dx.doi.org/10.1021/jm00172a035
International search[A]   YANG H.-J. ET AL.: "Effect of gabapentin derivatives on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 10, 2004, pages 2537 - 2541, XP001183105

DOI:   http://dx.doi.org/10.1016/j.bmcl.2004.02.094
by applicant  YARDELEY ET AL., J MED CHEM, vol. 33, 1990, pages 2899 - 2905
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