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Extract from the Register of European Patents

EP About this file: EP1948810

EP1948810 - COMPOSITION AND METHOD FOR EFFICIENT DELIVERY OF NUCLEIC ACIDS TO CELLS USING CHITOSAN [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  22.02.2013
Database last updated on 25.09.2024
Most recent event   Tooltip22.02.2013Application deemed to be withdrawnpublished on 27.03.2013  [2013/13]
Applicant(s)For all designated states
Polyvalor, Limited Partnership
5160 Decarie Blvd, Suite 770
Montreal, QC H3X 2H9 / CA
[2010/36]
Former [2008/31]For all designated states
Biosyntech Canada Inc.
475 Armand Frappier Boulevard Laval
Québec H7V 4B3 / CA
Inventor(s)01 / BUSCHMANN, Michael D.
4329, Avenue King-Edward
Montréal, Québec H4B 2H4 / CA
02 / LAVERTU, Marc
2735, Boulevard Toupin
Saint-Laurent, Québec H4R 1G7 / CA
03 / MÉTHOT, Stéphane
3922, Rue Saint-André
Montréal, Québec H2L 3W1 / CA
 [2008/31]
Representative(s)McDade, Sophie V.G.A.
Murgitroyd & Company
Scotland House
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2008/31]Coret, Sophie V.G.A.
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date06846908.906.11.2006
[2008/31]
WO2006CA01813
Priority number, dateUS20050733173P04.11.2005         Original published format: US 733173 P
[2008/31]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007059605
Date:31.05.2007
Language:EN
[2007/22]
Type: A1 Application with search report 
No.:EP1948810
Date:30.07.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 31.05.2007 takes the place of the publication of the European patent application.
[2008/31]
Search report(s)International search report - published on:CA31.05.2007
(Supplementary) European search report - dispatched on:EP28.05.2010
ClassificationIPC:C12N15/87, A61K31/70, A61K31/715, A61K48/00, C12N15/09, C12N15/85
[2008/31]
CPC:
C12N15/87 (EP,US); A61K31/70 (EP,US); A61K31/715 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/31]
TitleGerman:ZUSAMMENSETZUNG UND VERFAHREN ZUR EFFIZIENTEN VERABREICHUNG VON NUKLEINSÄUREN IN ZELLEN MITHILFE VON CHITOSAN[2008/31]
English:COMPOSITION AND METHOD FOR EFFICIENT DELIVERY OF NUCLEIC ACIDS TO CELLS USING CHITOSAN[2008/31]
French:COMPOSITION ET PROCEDE UTILISANT DU CHITOSAN POUR L'ADMINISTRATION EFFICACE D'ACIDES NUCLEIQUES A DES CELLULES[2008/31]
Entry into regional phase26.05.2008National basic fee paid 
26.05.2008Search fee paid 
26.05.2008Designation fee(s) paid 
26.05.2008Examination fee paid 
Examination procedure26.05.2008Examination requested  [2008/31]
15.12.2010Amendment by applicant (claims and/or description)
23.03.2012Despatch of a communication from the examining division (Time limit: M06)
03.10.2012Application deemed to be withdrawn, date of legal effect  [2013/13]
09.11.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2013/13]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.03.2012
Fees paidRenewal fee
27.10.2008Renewal fee patent year 03
27.11.2009Renewal fee patent year 04
18.11.2010Renewal fee patent year 05
29.11.2011Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
30.11.201207   M06   Not yet paid
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Documents cited:Search[A]  - MANSOURI S ET AL, "Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL LNKD- DOI:10.1016/S0939-6411(03)00155-3, (20040101), vol. 57, no. 1, ISSN 0939-6411, pages 1 - 8, XP004518747 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0939-6411(03)00155-3
International search[X]WO9742975  ;
 [X]US2003039665  ;
 [X]  - HUANG M. ET AL., "Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation", PHARM. RES., (200402), vol. 21, no. 2, pages 344 - 353, XP003013916

DOI:   http://dx.doi.org/10.1023/B:PHAM.0000016249.52831.a5
 [X]  - KIANG T. ET AL., "The effect of the degree of chitosan deacetylation on the efficiency of gene transfection", BIOMATERIALS, (200410), vol. 25, no. 22, pages 5293 - 5301, XP004504220

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2003.12.036
 [X]  - ROMOREN K. ET AL., "The influence of formulation variables on in vitro transfection efficiency and physicochemical properties of chitosan-based polyplexes", INT. J. PHARM., (20050811), vol. 261, no. 1-2, pages 115 - 127, XP003013917

DOI:   http://dx.doi.org/10.1016/S0378-5173(03)00301-6
 [X]  - HUANG M. ET AL., "Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation", J. CONTROL RELEASE, (20050902), vol. 106, no. 3, pages 391 - 406, XP005038459
 [X]  - KöPING-HöGGARD M. ET AL., "Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo", GENE THER., (200107), vol. 8, no. 1, pages 1108 - 1121, XP002967348

DOI:   http://dx.doi.org/10.1038/sj.gt.3301492
 [XP]  - LAVERTU M. ET AL., "High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation", BIOMATERIALS, (200609), vol. 27, no. 27, pages 4815 - 4824, XP005495427

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2006.04.029
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.