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Extract from the Register of European Patents

EP About this file: EP1908461

EP1908461 - Use of (1S, 2R) enantiomer of milnacipran for the preparation of a medicine [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.01.2012
Database last updated on 28.09.2024
Most recent event   Tooltip20.01.2012No opposition filed within time limitpublished on 22.02.2012  [2012/08]
Applicant(s)For all designated states
PIERRE FABRE MEDICAMENT
45, Place Abel Gance
92100 Boulogne-Billancourt / FR
[2008/15]
Inventor(s)01 / Deregnaucourt, Jean
11, Boulevard Edgar Quinet
75014, PARIS / FR
02 / Grosse, Richard
319, rue du Bourg
45520, GIDY / FR
 [2008/15]
Representative(s)Ahner, Francis, et al
Cabinet Regimbeau
20, rue de Chazelles
75847 Paris Cedex 17 / FR
[N/P]
Former [2009/49]Ahner, Francis, et al
Cabinet Régimbeau 20, rue de Chazelles
75847 Paris cedex 17 / FR
Former [2008/15]Ahner, Francis, et al
Cabinet Régimbeau, 20, rue de Chazelles
75847 Paris Cedex 17 / FR
Application number, filing date07123564.216.02.2004
[2008/15]
Priority number, dateFR2003000184914.02.2003         Original published format: FR 0301849
US2003045357403.06.2003         Original published format: US 453574
[2008/15]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report 
No.:EP1908461
Date:09.04.2008
Language:FR
[2008/15]
Type: B1 Patent specification 
No.:EP1908461
Date:16.03.2011
Language:FR
[2011/11]
Type: B9 Corrected patent specification 
No.:EP1908461
Date:31.08.2011
[2011/35]
Search report(s)(Supplementary) European search report - dispatched on:EP04.03.2008
ClassificationIPC:A61K31/135, A61K31/165
[2008/15]
CPC:
A61K31/135 (EP,KR,US); A61K31/165 (EP,KR,US); A61K31/167 (EP,US);
A61K31/195 (EP,US); A61K31/4015 (EP,US); A61P13/02 (EP);
A61P13/10 (EP); A61P25/00 (EP); A61P25/04 (EP);
A61P25/16 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P25/30 (EP); A61P3/04 (EP);
A61P9/00 (EP) (-)
C-Set:
A61K31/135, A61K2300/00 (EP,US);
A61K31/165, A61K2300/00 (US,EP);
A61K31/195, A61K2300/00 (US,EP);
A61K31/4015, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2008/15]
Extension statesAL19.12.2007
LT19.12.2007
LV19.12.2007
MK19.12.2007
TitleGerman:Verwendung des Enantiomers (1S, 2R) von Milnacipran zur Herstellung eines Arzneimittels[2008/15]
English:Use of (1S, 2R) enantiomer of milnacipran for the preparation of a medicine[2008/15]
French:Utilisation de l'énantiomère (1S, 2R) du milnacipran pour la préparation d'un médicament[2010/42]
Former [2008/15]Utilisation de l' énantiomère (1S, 2R) du milnacipran pour la préparation d' un médicament
Examination procedure19.12.2007Examination requested  [2008/15]
22.07.2008Despatch of a communication from the examining division (Time limit: M06)
21.01.2009Reply to a communication from the examining division
09.04.2009Despatch of a communication from the examining division (Time limit: M06)
08.10.2009Reply to a communication from the examining division
06.09.2010Cancellation of oral proceeding that was planned for 28.09.2010
28.09.2010Date of oral proceedings (cancelled)
04.11.2010Communication of intention to grant the patent
24.01.2011Fee for grant paid
24.01.2011Fee for publishing/printing paid
Parent application(s)   TooltipEP04711387.3  / EP1601349
Divisional application(s)EP10182592.5  / EP2305225
Opposition(s)19.12.2011No opposition filed within time limit [2012/08]
Fees paidRenewal fee
19.12.2007Renewal fee patent year 03
19.12.2007Renewal fee patent year 04
19.12.2007Renewal fee patent year 05
19.01.2009Renewal fee patent year 06
18.01.2010Renewal fee patent year 07
14.01.2011Renewal fee patent year 08
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY16.03.2011
[2011/41]
Documents cited:Search[X]FR2759906  (PF MEDICAMENT [FR]) [X] 1-5,7-10 * page 2, line 10 - line 16 * * page 2, line 17 - line 19 * * revendication *;
 [X]  - BONNAUD B ET AL, "1-Aryl-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1987), vol. 30, no. 2, ISSN 0022-2623, pages 318 - 325, XP002282456 [X] 1-10 * example 25 *

DOI:   http://dx.doi.org/10.1021/jm00385a013
 [X]  - DEPREZ D ET AL, "Which bioequivalence study for a racemic drug? Application to milnacipran.", EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, (1998), vol. 23, no. 2, ISSN 0378-7966, pages 166 - 171, XP008021090 [X] 1-5,7-10 * page 166, column L, paragraph 1 *
 [X]  - SPENCER CAROLINE M ET AL, "Milnacipran: A review of its use in depression.", DRUGS, (1998), vol. 56, no. 3, ISSN 0012-6667, pages 405 - 427, XP008021105 [X] 1-5,7-10 * page 410, column L, paragraph 1 *

DOI:   http://dx.doi.org/10.2165/00003495-199856030-00010
 [X]  - PUOZZO C ET AL, "Pharmacokinetics of milnacipran in renal impairment.", EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. SWITZERLAND 1998 APR-JUN, (199804), vol. 23, no. 2, ISSN 0398-7639, pages 280 - 286, XP008021091 [X] 1-5,7-10 * page 280, column R, paragraph 3 *
 [X]  - VIAZZO P ET AL, "Microbiological Transformations 34: Enantioselective Hydrolysis of a Key-Lactone Involved in the Synthesis of the Antidepressant Milnacipran@?", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19960624), vol. 37, no. 26, ISSN 0040-4039, pages 4519 - 4522, XP004029055 [X] 1-5,7-10 * page 4519, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/0040-4039(96)00872-6
 [X]  - SHUTO SATOSHI ET AL, "-1-phenyl-2-((S)-1-aminopropyl)-N,N-diethylcyclopropanecarboxamide (PPDC), a new class of NMDA-receptor antagonist: Molecular design by a novel conformational restriction strategy.", JAPANESE JOURNAL OF PHARMACOLOGY, (200103), vol. 85, no. 3, ISSN 0021-5198, pages 207 - 213, XP008021088 [X] 1-5,7-10 * page 207, abregé * * page 212, column L, paragraph 5 - paragraph 6 *

DOI:   http://dx.doi.org/10.1254/jjp.85.207
by applicantUS4478836
 WO9735574
 FR2759290
 EP0939626
 WO0126623
 WO0162236
    - MORET ET AL., NEUROPHARMACOLOGY, (1985), vol. 24, no. 12, pages 1211 - 1219
    - PALMIER ET AL., EUR J CLIN PHARMACOL, (1989), vol. 37, pages 235 - 238
    - BONNAUD ET AL., JOURNAL OFCHROMATOGRAPHY, (1985), vol. 318, pages 398 - 403
    - SHUTO ET AL., TETRAHEDRON LETTERS, (1996), vol. 37, pages 641 - 644
    - GRARD ET AL., ELECTROPHORESIS, (2000), vol. 21, pages 3028 - 3034
    - DOYLE; HU, ADVANCED SYNTHESIS AND CATALYSIS, (2001), vol. 343, pages 299 - 302
    - NORES ET AL., THéRAPIE, (1987), vol. 42, pages 555 - 558
    - MEADOER-WOODRUFF ET AL., J. CLIM. PSYCHOPHARMACOL., (1988), vol. 8, pages 28 - 32
    - GRAY; WHITTAKER, J. ANAT., (1962), vol. 96, pages 79 - 97
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.