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EP About this file: EP2168984

EP2168984 - Human antibodies that bind human IL-12 and methods for producing [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  16.10.2015
Database last updated on 28.09.2024
Most recent event   Tooltip08.01.2016Lapse of the patent in a contracting statepublished on 10.02.2016  [2016/06]
Applicant(s)For all designated states
AbbVie Deutschland GmbH & Co KG
Max-Planck-Ring 2a
65205 Wiesbaden / DE
[2013/42]
Former [2010/13]For all designated states
Abbott GmbH & Co. KG
Max-Planck-Ring 2
65205 Wiesbaden / DE
Inventor(s)01 / Salfeld, Jochen
177 Old Westborogh Road
North Gafton, MA 01536 / US
02 / Roguska, Michael
16 Hilldale Road
Ashland, MA 01721 / US
03 / Paskind, Michael
253 Redemption Rock Trail
Sterling, MA 01564 / US
04 / Banerjee, Subhashis
77 Dunbar Lane
Hamden, CT 06514 / US
05 / Tracey, Daniel E.
149 Shaker Road
Harvard, MA 01451 / US
06 / White, Michael
30 Angelica Drive
Framingham, MA 01701 / US
07 / Kaymakcalan, Zehra
4 Picadilly Way
Westborough, MA 01581 / US
08 / Labkovsky, Boris
107A-5 Broadmeadow Road
Marlborough, MA 01752 / US
09 / Sakorafas, Paul
25 Old Winchester Street
Newton Highlands, MA 02461 / US
10 / Friedrich, Stuart
20 Albion Street
Melrose, MA 02176 / US
11 / Myles, Angela
118 South Road
Pepperell, MA 01463 / US
12 / Veldman, Geertruida M.
60 Woodmere Drive
Sudbury, MA 01776 / US
13 / Venturini, Amy
3901 Cathedral Bell Road
Raleigh, NC 27614 / US
14 / Warne, Nicholas W.
27 Farrwood Drive
Andover, MA 01810 / US
15 / Widom, Angela
19 Cherokee Road
Acton, MA 01720 / US
16 / Elvin, John G.
36 Perowne Street
Cambridge Cambridgeshire CB1 2AY / GB
17 / Duncan, Alexander R.
3 Hauwxton Road
Little Shelford
Cambridge Cambridgeshire CB2 5HJ / GB
18 / Derbyshire, Elaine J.
14 Towers Drive
Crowthorne
Berks Berkshire RG45 7LR / GB
19 / Carmen, Sara
136 Sturton Street
Cambridge Cambridgeshire CB1 2QF / GB
20 / Smith, Stephen
33 Church Road
Wicken
Ely Cambridgeshire CB7 5XT / GB
21 / Holtet, Thor Las
Strandvejen 4
8410 Rønde / DK
22 / Du Fou, Sarah L.
76 Ickleford Road
Hitchen Hertfordshire SG5 1TL / GB
 [2012/30]
Former [2010/17]01 / Salfeld, Jochen
177 Old Westborogh Road
North Gafton, MA 01536 / US
02 / Roguska, Michael
16 Hilldale Road
Ashland, MA 01721 / US
03 / Paskind, Michael
253 Redemption Rock Trail
Sterling, MA 01564 / US
04 / Banerjee, Subhashis
77 Dunbar Lane
Hamden, CT 06514 / US
05 / Tracey, Daniel E.
149 Shaker Road
Harvard, MA 01451 / US
06 / White, Michael
30 Angelica Drive
Framingham, MA 01701 / US
07 / Kaymakcalan, Zehra
4 Picadilly Way
Westborough, MA 01581 / US
08 / Labkovsky, Boris
107A-5 Broadmeadow Road
Marlborough, MA 01752 / US
09 / Sakorafas, Paul
25 Old Winchester Street
Newton Highlands, Massachusetts 02461 / US
10 / Friedrich, Stuart
20 Albion Street
Melrose, MA 02176 / US
11 / Myles, Angela
118 South Road
Pepperell, Massachusetts 01463 / US
12 / Veldman, Geertruida M.
60 Woodmere Drive
Sudbury, MA 01776 / US
13 / Venturini, Amy
3901 Cathedral Bell Road
Raleigh, North Carolina 27614 / US
14 / Warne, Nicholas W.
27 Farrwood Drive
Andover, MA 01810 / US
15 / Widom, Angela
19 Cherokee Road
Acton, MA 01720 / US
16 / Elvin, John G.
36 Perowne Street
Cambridge Cambridgeshire CB1 2AY / GB
17 / Duncan, Alexander R.
3 Hauwxton Road Little Shelford
Cambridge Cambridgeshire CB2 5HJ / GB
18 / Derbyshire, Elaine J.
14 Towers Drive Crowthorne
Berks Berkshire RG45 7LR / GB
19 / Carmen, Sara
136 Sturton Street
Cambridge Cambridgeshire CB1 2QF / GB
20 / Smith, Stephen
33 Church Road Wicken
Ely Cambridgeshire CB7 5XT / GB
21 / Holtet, Thor Las
Strandvejen 4
8410 Rønde / DK
22 / Du Fou, Sarah L.
76 Ickleford Road
Hitchen Hertfordshire SG5 1TL / GB
Former [2010/16]01 / Salfeld, Jochen
177 Old Westborogh Road
North Gafton, MA 01536 / US
02 / Roguska, Michael
16 Hilldale Road
Ashland, MA 01721 / US
03 / Paskind, Michael
253 Redemption Rock Trail
Sterling, MA 01564 / US
04 / Banerjee, Subhashis
77 Dunbar Lane
Hamden, CT 06514 / US
05 / Tracey, Daniel E.
149 Shaker Road
Harvard, MA 01451 / US
06 / White, Michael
30 Angelica Drive
Framingham, MA 01701 / US
07 / Kaymakcalan, Zehra
4 Picadilly Way
Westborough, MA 01581 / US
08 / Labkovsky, Boris
107A-5 Broadmeadow Road
Marlborough, MA 01752 / US
09 / Sakorafas, Paul
47 Court Street
Newton, MA 02160 / US
10 / Friedrich, Stuart
20 Albion Street
Melrose, MA 02176 / US
11 / Myles, Angela
Apartment No. 7 11 Crescent Drive
Andover, MA 01810 / US
12 / Veldman, Geertruida M.
60 Woodmere Drive
Sudbury, MA 01776 / US
13 / Venturini, Amy
207 Woburn Street
Lexington, MA 02420 / US
14 / Warne, Nicholas W.
27 Farrwood Drive
Andover, MA 01810 / US
15 / Widom, Angela
19 Cherokee Road
Acton, MA 01720 / US
16 / Elvin, John G.
36 Perowne Street
Cambridge Cambridgeshire CB1 2AY / GB
17 / Duncan, Alexander R.
3 Hauwxton Road Little Shelford
Cambridge Cambridgeshire CB2 5HJ / GB
18 / Derbyshire, Elaine J.
14 Towers Drive Crowthorne
Berks Berkshire RG45 7LR / GB
19 / Carmen, Sara
136 Sturton Street
Cambridge Cambridgeshire CB1 2QF / GB
20 / Smith, Stephen
33 Church Road Wicken
Ely Cambridgeshire CB7 5XT / GB
21 / Holtet, Thor Las
Strandvejen 4
8410 Rønde / DK
22 / Du Fou, Sarah L.
76 Ickleford Road
Hitchen Hertfordshire SG5 1TL / GB
Former [2010/13]01 / Salfeld, Jochen
177 Old Westborogh Road
North Gafton, MA 01536 / US
02 / Roguska, Michael
16 Hilldale Road
Ashland, MA 01721 / US
03 / Paskind, Michael
253 Redemption Rock Trail
Sterling, MA 01564 / US
04 / Banerjee, Subhashis
77 Dunbar Lane
Hamden, CT 06514 / US
05 / Tracey, Daniel E.
149 Shaker Road
Harvard, MA 01451 / US
06 / White, Michael
30 Angelica Drive
Framingham, MA 01701 / US
07 / Kaymakcalan, Zehra
4 Picadilly Way
Westborough, MA 01581 / US
08 / Labkovsky, Boris
107A-5 Broadmeadow Road
Marlborough, MA 01752 / US
09 / Sakorafas, Paul
47 Court Street
Newton, MA 02160 / US
10 / Friedrich, Stuart
20 Albion Street
Melrose, MA 02176 / US
11 / Myles, Angela
Apartment No. 7 11 Crescent Drive
Andover, MA 01810 / US
12 / Veldman, Geertruida M.
60 Woodmere Drive
Sudbury, MA 01776 / US
13 / Venturini, Amy
207 Woburn Street
Lexington, MA 02420 / US
14 / Warne, Nicholas W.
27 Farrwood Drive
Andover, MA 01810 / US
15 / Widom, Angela
19 Cherokee Road
Acton, MA 01720 / US
16 / Elvin, John G.
36 Perowne Street
Cambridge Cambridgeshire CB1 2AY / GB
17 / Duncan, Alexander R.
3 Hauwxton Road Little Shelford
Cambridge Cambridgeshire CB2 5HJ / GB
18 / Derbyshire, Elaine J.
14 Towers Drive Crowthorne
Berks Berkshire RG45 7LR / GB
19 / Carmen, Sara
136 Sturton Street
Cambridge Cambridgeshire CB1 2QF / GB
20 / Smith, Stephen
33 Church Road Wicken Ely
Cambridgeshire Cambridgeshire CB7 5XT / GB
21 / Holtet, Thor Las
13 Mortimer Road Royston
Hertfordshire Hertfordshire / GB
22 / Du Fou, Sarah L.
76 Ickleford Road Hitchen
Hertfordshire Hertfordshire SG5 1TL / GB
Representative(s)Adams, Harvey Vaughan John
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2013/49]Adams, Harvey Vaughan John
Mathys & Squire LLP
120 Holborn
London EC1N 2SQ / GB
Former [2010/13]Modiano, Micaela Nadia, et al
Modiano & Partners Thierschstrasse 11
80538 München / DE
Application number, filing date09175437.424.03.2000
[2010/13]
Priority number, dateUS19990126603P25.03.1999         Original published format: US 126603 P
[2010/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2168984
Date:31.03.2010
Language:EN
[2010/13]
Type: B1 Patent specification 
No.:EP2168984
Date:29.08.2012
Language:EN
[2012/35]
Search report(s)(Supplementary) European search report - dispatched on:EP02.03.2010
ClassificationIPC:C07K16/24, C12N15/13, C12N15/63, C12N5/10, C07K16/00, A61K39/395, G01N33/577, C12P21/08, A61P43/00
[2010/13]
CPC:
C07K16/00 (EP); C07K16/24 (KR); A61P1/00 (EP);
A61P1/04 (EP); A61P1/16 (EP); A61P11/00 (EP);
A61P11/06 (EP); A61P11/08 (EP); A61P11/16 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P17/02 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P19/08 (EP);
A61P21/02 (EP); A61P21/04 (EP); A61P25/00 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/28 (EP);
A61P27/02 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P31/00 (EP); A61P31/04 (EP); A61P31/18 (EP);
A61P33/00 (EP); A61P35/00 (EP); A61P37/00 (EP);
A61P37/02 (EP); A61P37/04 (EP); A61P37/06 (EP);
A61P37/08 (EP); A61P43/00 (EP); A61P5/14 (EP);
A61P5/16 (EP); A61P7/00 (EP); A61P7/02 (EP);
A61P7/04 (EP); A61P7/06 (EP); A61P9/00 (EP);
A61P9/04 (EP); A61P9/10 (EP); A61P9/14 (EP);
C07K16/244 (EP); A61K2039/505 (EP); C07K2317/21 (EP);
C07K2317/565 (EP); C07K2317/622 (EP); C07K2317/73 (EP);
C07K2317/76 (EP); C07K2317/92 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2010/13]
Extension statesRO02.09.2010
SI02.09.2010
TitleGerman:Humane Antikörper die humanes IL-12 binden und Herstellungsverfahren[2010/13]
English:Human antibodies that bind human IL-12 and methods for producing[2010/13]
French:Anticorps humains qui se lient au IL-12 humain et procédé de fabrication[2010/13]
Examination procedure02.09.2010Examination requested  [2010/42]
23.09.2010Observations by third parties
29.10.2010Despatch of a communication from the examining division (Time limit: M06)
04.05.2011Reply to a communication from the examining division
15.06.2011Observations by third parties
21.07.2011Despatch of a communication from the examining division (Time limit: M04)
30.11.2011Reply to a communication from the examining division
23.01.2012Despatch of a communication from the examining division (Time limit: M04)
26.01.2012Observations by third parties
07.02.2012Reply to a communication from the examining division
23.02.2012Observations by third parties
29.06.2012Communication of intention to grant the patent
13.07.2012Fee for grant paid
13.07.2012Fee for publishing/printing paid
16.07.2012Observations by third parties
Parent application(s)   TooltipEP00918396.3  / EP1175446
Divisional application(s)EP10180107.4  / EP2301970
EP10180283.3  / EP2319870
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20000918396) is  09.06.2005
Opposition(s)Opponent(s)01  02.04.2013  19.01.2015  WITHDRAWN
Janssen Biotech, Inc.
800/850 Ridgeview Drive
Horsham
PA 19044 / US
Opponent's representative
Wise, Daniel Joseph
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
 [2015/09]
Former [2013/19]
Opponent(s)01  02.04.2013    WITHDRAWN
Janssen Biotech, Inc.
800/850 Ridgeview Drive
Horsham
PA 19044 / US
Opponent's representative
Wise, Daniel Joseph
Carpmaels & Ransford
One Southampton Row
London WC1B 5HA / GB
08.07.2013Invitation to proprietor to file observations on the notice of opposition
04.11.2013Reply of patent proprietor to notice(s) of opposition
19.09.2014Date of oral proceedings
10.10.2014Despatch of minutes of oral proceedings
10.10.2014Despatch of communication that the patent will be revoked
10.10.2015Legal effect of revocation of patent [2015/47]
Appeal following opposition03.10.2014Appeal received No.  T2019/14
22.09.2015Result of appeal procedure: appeal of the proprietor inadmissible
Fees paidRenewal fee
09.11.2009Renewal fee patent year 03
09.11.2009Renewal fee patent year 04
09.11.2009Renewal fee patent year 05
09.11.2009Renewal fee patent year 06
09.11.2009Renewal fee patent year 07
09.11.2009Renewal fee patent year 08
09.11.2009Renewal fee patent year 09
09.11.2009Renewal fee patent year 10
30.03.2010Renewal fee patent year 11
10.03.2011Renewal fee patent year 12
07.03.2012Renewal fee patent year 13
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCH29.08.2012
LI29.08.2012
[2016/06]
Documents cited:Search[A]WO9404679  (GENENTECH INC [US]) [A] 1-112 * page 5, line 1 - page 7, line 3 * * example 3 * * claim - *;
 [A]EP0659766  (SCHERING PLOUGH CORP [FR]) [A] 1-112 * the whole document * * page 3, line 34 - page 4, line 33 * * claim - *;
 [A]WO9524918  (GENETICS INST [US]) [A] 1-112 * the whole document *;
 [A]WO9822137  (KENNEDY INST OF RHEUMATOLOGY [GB], et al) [A] 1-112 * the whole document *;
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DOI:   http://dx.doi.org/10.1016/S0022-1759(97)00107-5
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    - NICHOLSON I C ET AL, "Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, (19990101), vol. 163, ISSN 0022-1767, pages 6898 - 6906, XP002974255
    - ROVAI LEONOR E ET AL, "The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia", JOURNAL OF LEUKOCYTE BIOLOGY, (199810), vol. 64, no. 4, ISSN 0741-5400, pages 494 - 502
    - MACCALLUM R M ET AL, "Antibody-antigen interactions: Contact analysis and binding site topography", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (19960101), vol. 262, no. 5, doi:10.1006/JMBI.1996.0548, ISSN 0022-2836, pages 732 - 745, XP002242391

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DOI:   http://dx.doi.org/10.1016/S0167-7799(97)84205-9
by applicantUS4399216
 US4510245
 US4634665
 US4816397
 US4968615
 WO9201047
 WO9209690
 WO9218619
 WO9220791
 US5168062
 US5179017
 WO9301288
 US5464758
 WO9715327
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