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Extract from the Register of European Patents

EP About this file: EP2321273

EP2321273 - ONCE-A-WEEK ADMINISTRATION OF 25-HYDROXY VITAMIN D3 TO SUSTAIN ELEVATED STEADY-STATE PHARMACOKINETIC BLOOD CONCENTRATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.09.2015
Database last updated on 28.09.2024
Most recent event   Tooltip25.09.2015No opposition filed within time limitpublished on 28.10.2015  [2015/44]
Applicant(s)For all designated states
Wisconsin Alumni Research Foundation
614 Walnut Street
Madison, WI 53705 / US
[2014/47]
Former [2011/20]For all designated states
Wisconsin Alumni Research Foundation
614 Walnut Street
Madison, WI 53705 / US
Inventor(s)01 / DELUCA, Hector, F.
1809 Hwy. Bb
Deerfield WI 53531 / US
02 / PLUM, Lori, A.
6139 Hwy. H.
Arena WI 53503 / US
03 / CLAGETT-DAME, Margaret
1809 Hwy. Bb
Deerfield WI 52531 / US
 [2011/20]
Representative(s)Duckworth, Timothy John, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2013/37]
Former [2011/20]McCluskie, Gail Wilson, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date09801055.624.07.2009
[2011/20]
WO2009US51664
Priority number, dateUS20080083223P24.07.2008         Original published format: US 83223 P
[2011/20]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010011906
Date:28.01.2010
Language:EN
[2010/04]
Type: A1 Application with search report 
No.:EP2321273
Date:18.05.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 28.01.2010 takes the place of the publication of the European patent application.
[2011/20]
Type: B1 Patent specification 
No.:EP2321273
Date:19.11.2014
Language:EN
[2014/47]
Search report(s)International search report - published on:US28.01.2010
(Supplementary) European search report - dispatched on:EP03.11.2011
ClassificationIPC:C07C401/00
[2011/20]
CPC:
A61K31/593 (EP,US); A61P3/02 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/20]
TitleGerman:EINMAL WÖCHENTLICHE VERABREICHUNG VON 25-HYDROXY-VITAMIN D3 ZUR BEWAHRUNG EINER ERHÖHTEN STABILEN PHARMAKOKINETISCHEN BLUTKONZENTRATION[2011/20]
English:ONCE-A-WEEK ADMINISTRATION OF 25-HYDROXY VITAMIN D3 TO SUSTAIN ELEVATED STEADY-STATE PHARMACOKINETIC BLOOD CONCENTRATION[2011/20]
French:ADMINISTRATION HEBDOMADAIRE DE 25-HYDROXY VITAMINE D3 POUR MAINTENIR UNE CONCENTRATION SANGUINE À PHARMACOCINÉTIQUE STABLE ÉLEVÉE[2011/20]
Entry into regional phase21.02.2011National basic fee paid 
21.02.2011Search fee paid 
21.02.2011Designation fee(s) paid 
21.02.2011Examination fee paid 
Examination procedure21.02.2011Examination requested  [2011/20]
22.05.2012Amendment by applicant (claims and/or description)
25.10.2012Despatch of a communication from the examining division (Time limit: M06)
18.04.2013Reply to a communication from the examining division
05.07.2013Despatch of a communication from the examining division (Time limit: M06)
07.02.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
10.04.2014Reply to a communication from the examining division
06.06.2014Communication of intention to grant the patent
07.10.2014Fee for grant paid
07.10.2014Fee for publishing/printing paid
07.10.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.10.2012
Opposition(s)20.08.2015No opposition filed within time limit [2015/44]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.04.2014Request for further processing filed
10.04.2014Full payment received (date of receipt of payment)
Request granted
24.04.2014Decision despatched
Fees paidRenewal fee
12.07.2011Renewal fee patent year 03
13.07.2012Renewal fee patent year 04
10.07.2013Renewal fee patent year 05
14.07.2014Renewal fee patent year 06
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Documents cited:Search[X]  - ISH-SHALOM S ET AL, "SU428: Daily, weekly or monthly protocols to reach the desired serum 25-hydroxyvitamin D concentration for the elderly", JOURNAL OF BONE AND MINERAL RESEARCH; 27TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-FOR-BONE-AND-MINERAL-RESEARCH, AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH, NEW YORK, NY, US; NASHVILLE, TN, USA, (20050901), vol. 20, no. 9, Suppl. 1, ISSN 0884-0431, page S288, XP009153422 [X] 1-13 * abstract *
International search[Y]US2003195171  (DAIFOTIS ANASTASIA G [US], et al);
 [Y]US2005003004  (VEHRING REINHARD [US], et al);
 [Y]US2005101576  (WHITEHOUSE MARTHA J [US], et al);
 [Y]  - HEANEY ET AL, "25-Hydroxylation of Vitamin D3: Relation to Circulating Vitamin D3 Under Various Input Conditions", AM J CLIN NUTR, (200806), vol. 87, pages 1738 - 1742, XP008143060
by applicantUS3607888
    - BLUNT JW ET AL., "25-Hydroxycholecalciferol: A biologically active metabolite of vitamin D3", BIOCHEMISTRY, (1968), vol. 7, pages 3317 - 3322
    - JONES G ET AL., "Current understanding of the molecular actions of vitamin D", PHYSIOL. REV., (1998), vol. 78, pages 1193 - 1231
    - GORHAM ED ET AL., "Optimal vitamin D status for colorectal cancer prevention - A quantitative meta analysis", AM,J. PREV. MED., (2007), vol. 32, no. 3, pages 210 - 216
    - GARLAND CF ET AL., "Vitamin D and prevention of breast cancer: Pooled analysis", J. STEROID BIOCHEM, AND MOL. BIOL., (2007), vol. 103, pages 3 - 5
    - LI HJ ET AL., "A prospective study of plasma vitamin D metabolites, vitamin D receptor polymorphisms, and prostate cancer", PLOS MEDICINE, (2007), vol. 4, no. 3, pages 562 - 571
    - MUNGER KL ET AL., "Elevated serum 25-hydroxyvitamin D predicts a decreased risk of MS", MULTIPLE SCLEROSIS, (2007), vol. 13, no. 2, page 290
    - LOOKER AC ET AL., "Serum 25-hydroxyvitamin D status of adolescent and adults in two seasonal subpopulations from NHANES III", BONE, (2002), vol. 30, no. 5, pages 771 - 777
    - THACHER TD ET AL., "Nutritional rickets around the world: causes and future directions", ANNALS OF TROPICAL PAEDIATRICS, (2006), vol. 26, no. 1, pages 1 - 16
    - LOOKER AC ET AL., "Serum 25-hydroxyvitamin D and hip fracture risk in older U.S. white adults", J. BONE MIN. RES., (2008), vol. 23, no. 1, pages 143 - 150
    - CHONCHOL M ET AL., "25-Hydroxyvitamin D, insulin resistance, and kidney function in the. Third National Health and Nutrition Examination Survey", KIDNEY INT., (2007), vol. 71, no. 2, pages 134 - 139
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.