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Extract from the Register of European Patents

EP About this file: EP2551341

EP2551341 - CULTURE METHOD FOR CAUSING DIFFERENTIATION OF PLURIPOTENT MAMMALIAN CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.03.2018
Database last updated on 28.09.2024
FormerThe patent has been granted
Status updated on  24.03.2017
FormerGrant of patent is intended
Status updated on  10.11.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Kuraray Co., Ltd.
1621, Sakazu Kurashiki-shi
Okayama 710-0801 / JP
For all designated states
Public University Corporation Yokohama City University
22-2 Seto Kanazawa-ku
Yokohama-shi, Kanagawa 236-0027 / JP
[2013/05]
Inventor(s)01 / ITCHODA, Yoko
c/o KURARAY Co., Ltd.
41 Miyukigaoka
Tsukuba-shi Ibaraki 305-0841 / JP
02 / TAZAKI, Go
c/o KURARAY Co., Ltd.
41 Miyukigaoka
Tsukuba-shi Ibaraki 305-0841 / JP
03 / HOSODA, Masaya
c/o KURARAY Co., Ltd.
41 Miyukigaoka
Tsukuba-shi Ibaraki 305-0841 / JP
04 / FUKUDA, Motohiro
c/o KURARAY Co., Ltd.
41 Miyukigaoka
Tsukuba-shi Ibaraki 305-0841 / JP
05 / TANIGUCHI, Hideki
c/o Public University Corporation
Yokohama City University
3-9-1 Fukuura
Kanazawa-ku
Yokohama-shi Kanagawa 236-0004 / JP
06 / ZHENG, Yun-Wen
c/o Public University Corporation
Yokohama City University
3-9-1 Fukuura
Kanazawa-ku
Yokohama-shi Kanagawa 236-0004 / JP
07 / SEKINE, Keisuke
c/o Public University Corporation
Yokohama City University
3-9-1 Fukuura
Kanazawa-ku
Yokohama-shi Kanagawa 236-0004 / JP
 [2013/05]
Representative(s)Müller-Boré & Partner Patentanwälte PartG mbB
Friedenheimer Brücke 21
80639 München / DE
[2017/17]
Former [2013/05]Müller-Boré & Partner Patentanwälte
Grafinger Straße 2
81671 München / DE
Application number, filing date11759020.823.03.2011
[2017/17]
WO2011JP01708
Priority number, dateJP2010006632423.03.2010         Original published format: JP 2010066324
[2013/05]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011118211
Date:29.09.2011
Language:JA
[2011/39]
Type: A1 Application with search report 
No.:EP2551341
Date:30.01.2013
Language:EN
[2013/05]
Type: B1 Patent specification 
No.:EP2551341
Date:26.04.2017
Language:EN
[2017/17]
Search report(s)International search report - published on:JP29.09.2011
(Supplementary) European search report - dispatched on:EP26.06.2013
ClassificationIPC:C12M1/32, C12N5/0735
[2016/47]
CPC:
C12N5/0606 (EP,US); C12N5/0018 (KR); C12M23/12 (EP,US);
C12M3/00 (KR); C12N5/00 (KR); C12N5/0056 (KR);
C12N5/0068 (KR); C12N2502/28 (EP,US); C12N2506/02 (EP,US);
C12N2535/10 (EP,US) (-)
Former IPC [2013/05]C12N5/071, C12M3/00, C12N5/0735
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/05]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:KULTURVERFAHREN ZUR HERBEIFÜHRUNG DER DIFFERENZIERUNG PLURIPOTENTER SÄUGETIERZELLEN[2013/05]
English:CULTURE METHOD FOR CAUSING DIFFERENTIATION OF PLURIPOTENT MAMMALIAN CELLS[2013/05]
French:PROCÉDÉ DE CULTURE CAPABLE DE PROVOQUER LA DIFFÉRENTIATION DE CELLULES PLURIPOTENTES DE MAMMIFÈRES[2013/05]
Entry into regional phase20.09.2012Translation filed 
27.09.2012National basic fee paid 
27.09.2012Search fee paid 
27.09.2012Designation fee(s) paid 
27.09.2012Examination fee paid 
Examination procedure08.02.1924Amendment by applicant (claims and/or description)
27.09.2012Examination requested  [2013/05]
20.05.2014Despatch of a communication from the examining division (Time limit: M06)
19.11.2014Reply to a communication from the examining division
01.07.2015Despatch of a communication from the examining division (Time limit: M06)
08.01.2016Reply to a communication from the examining division
11.11.2016Communication of intention to grant the patent
24.02.2017Receipt of the translation of the claim(s)
02.03.2017Fee for grant paid
02.03.2017Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  20.05.2014
Opposition(s)29.01.2018No opposition filed within time limit [2018/14]
Fees paidRenewal fee
28.03.2013Renewal fee patent year 03
27.03.2014Renewal fee patent year 04
30.03.2015Renewal fee patent year 05
22.03.2016Renewal fee patent year 06
20.03.2017Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.03.2011
AL26.04.2017
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
PT26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
[2020/33]
Former [2020/31]HU23.03.2011
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
PT26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2020/27]HU23.03.2011
AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
PT26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2020/15]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/52]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/25]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/11]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/10]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SK26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/09]AT26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RS26.04.2017
SE26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/50]AT26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RS26.04.2017
SE26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/49]AT26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
NL26.04.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/48]NL26.04.2017
Documents cited:Search[Y]WO2008156041  (KURARAY CO [JP], et al) [Y] 1-22 * the whole document *;
 [YP]EP2169049  (KURARAY CO [JP]) [YP] 1-22 * paragraph [0018] - paragraph [0038] *;
 [Y]WO2006020919  (UNIV GEORGIA RES FOUND [US], et al) [Y] 1-22 * examples 1-3 *;
 [IP]DE102009002577  (LEIBNIZ INST POLYMERFORSCHUNG [DE]) [IP] 1-22 * the whole document *;
 [A]WO2009150051  (UNIV AARHUS [DK], et al) [A] 1-22 * the whole document *
 [XI]  - Y.-S. HWANG ET AL, "Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20091006), vol. 106, no. 40, doi:10.1073/pnas.0905550106, ISSN 0027-8424, pages 16978 - 16983, XP055067093 [X] 1,2,14-18,20 * figures 1, 3 * [I] 1-22

DOI:   http://dx.doi.org/10.1073/pnas.0905550106
 [Y]  - MOELLER ET AL, "A microwell array system for stem cell culture", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, (20071114), vol. 29, no. 6, doi:10.1016/J.BIOMATERIALS.2007.10.030, ISSN 0142-9612, pages 752 - 763, XP022371128 [Y] 1-22 * figures 1, 7 *

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2007.10.030
 [Y]  - CÉLINE LIU BAUWENS ET AL, "Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories", STEM CELLS, (20080901), vol. 26, no. 9, doi:10.1634/stemcells.2008-0183, ISSN 1066-5099, pages 2300 - 2310, XP055067255 [Y] 1-22 * the whole document *

DOI:   http://dx.doi.org/10.1634/stemcells.2008-0183
 [T]  - SEKINE K ET AL, "Highly Efficient Generation of Definitive Endoderm Lineage from Human Induced Pluripotent Stem Cells", TRANSPLANTATION PROCEEDINGS, vol. 44, no. 4, doi:10.1016/J.TRANSPROCEED.2012.03.001, ISSN 0041-1345, (20120101), pages 1127 - 1129, (20120317), XP028482435 [T] * the whole document *

DOI:   http://dx.doi.org/10.1016/j.transproceed.2012.03.001
International search[Y]JP2008509676  (THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.);
 [Y]WO2008156041  (KURARAY CO [JP], et al);
 [XP]WO2010047132  (KURARAY CO [JP], et al);
 [A]JP2007061096  (LIFESCAN INC)
by applicantJP2008509676
    - CELINE LIU BAUWENS; RAHEEM PEERANI; SYLVIA NIEBRUEGGE; KIMBERLY A. WOODHOUSE; EUGENIA KUMACHEVA; MANSOOR HUSAIN; PETER W. ZANDSTRA, "Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories", STEM CELLS, (2008), vol. 26, doi:doi:10.1634/stemcells.2008-0183, pages 2300 - 2310, XP055067257

DOI:   http://dx.doi.org/10.1634/stemcells.2008-0183
    - HUDSON, C.; CLEMENTS, D.; FRIDAY, R.V.; STOTT, D.; WOODLAND, H.R., "Xsoxl7a and -$ mediate endoderm formation in Xenopus", CELL, (1997), vol. 91, pages 397 - 405
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