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Extract from the Register of European Patents

EP About this file: EP3169671

EP3169671 - 1-(5-(TERT.-BUTYL)ISOXAZOL-3-YL)-3-(4-((PHENYL)ETHYNYL)PHENYL)UREA DERIVATIVES AND RELATED COMPOUNDS AS FLT3 INHIBITORS FOR TREATING CANCER [Right-click to bookmark this link]
Former [2017/21]SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF
[2019/18]
StatusNo opposition filed within time limit
Status updated on  10.07.2020
Database last updated on 25.09.2024
FormerThe patent has been granted
Status updated on  19.07.2019
FormerGrant of patent is intended
Status updated on  25.04.2019
FormerExamination is in progress
Status updated on  23.11.2018
FormerRequest for examination was made
Status updated on  21.04.2017
FormerThe international publication has been made
Status updated on  28.11.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
Sunshine Lake Pharma Co., Ltd.
Northern Industrial Area
Songshan Lake
Dongguan, Guangdong 523000 / CN
[2017/21]
Inventor(s)01 / CHENG, Changchung
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
02 / ZHANG, Yingjun
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
03 / LIU, Bing
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
04 / LONG, Bohua
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
05 / CHEN, Yu
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
06 / CHENG, Zhixin
Dongyangguang Hi-tech Park
Zhen An Road No. 368
Shang Sha
Chang An Town
Dongguan Guangdong 523871 / CN
 [2017/21]
Representative(s)Becker Kurig & Partner Patentanwälte mbB
Bavariastraße 7
80336 München / DE
[N/P]
Former [2017/21]Becker Kurig Straus
Patentanwälte
Bavariastrasse 7
80336 München / DE
Application number, filing date15822879.116.07.2015
[2017/21]
WO2015CN84253
Priority number, dateCN20141034250917.07.2014         Original published format: CN201410342509
[2017/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016008433
Date:21.01.2016
Language:EN
[2016/03]
Type: A1 Application with search report 
No.:EP3169671
Date:24.05.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 21.01.2016 takes the place of the publication of the European patent application.
[2017/21]
Type: B1 Patent specification 
No.:EP3169671
Date:21.08.2019
Language:EN
[2019/34]
Search report(s)International search report - published on:CN21.01.2016
(Supplementary) European search report - dispatched on:EP31.01.2018
ClassificationIPC:C07D413/14, C07D491/08, C07D413/12, C07D417/12, C07D471/04, C07D261/14, C07D487/04, C07D491/056, C07D491/107, C07D513/04, C07D513/14, C07D519/00, A61K31/422, A61K31/437, A61K31/4439, A61K31/454, A61K31/4545, A61K31/496, A61K31/5025, A61K45/06, A61P35/00
[2019/18]
CPC:
C07D261/14 (EP,CN,KR,US); C07D413/12 (EP,CN,KR,US); A61K31/422 (EP,KR,US);
A61K31/437 (EP,US); A61K31/4439 (EP,US); A61K31/454 (EP,KR,US);
A61K31/4545 (EP,US); A61K31/496 (EP,US); A61K31/5025 (EP,US);
A61K31/519 (EP,US); A61K31/5377 (EP,KR,US); A61K31/541 (EP,US);
A61K45/06 (EP,KR,US); A61P35/00 (EP,US); C07D413/14 (EP,CN,US);
C07D417/12 (EP,CN,US); C07D471/04 (EP,CN,US); C07D487/04 (EP,CN,US);
C07D487/08 (CN); C07D491/056 (EP,CN,US); C07D491/08 (EP,CN,US);
C07D491/107 (EP,CN,US); C07D495/04 (CN); C07D513/04 (EP,CN,US);
C07D513/14 (EP,CN,US); C07D519/00 (EP,CN,US); A61K2300/00 (KR);
Y02A50/30 (EP) (-)
C-Set:
A61K31/422, A61K2300/00 (EP,US);
A61K31/437, A61K2300/00 (EP,US);
A61K31/4439, A61K2300/00 (EP,US);
A61K31/4545, A61K2300/00 (EP,US);
A61K31/454, A61K2300/00 (EP,US);
A61K31/496, A61K2300/00 (US,EP);
A61K31/519, A61K2300/00 (US,EP);
A61K31/5377, A61K2300/00 (US,EP);
A61K31/541, A61K2300/00 (US,EP)
(-)
Former IPC [2017/21]C07D261/14, C07D491/056, C07D413/12, C07D417/12, C07D471/04, C07D487/04, C07D491/107, C07D491/08, C07D413/14, C07D519/00, C07D513/04, C07D513/14, A61K31/541, A61K31/5377, A61K31/437, A61K31/496, A61K31/519, A61K31/4439, A61K31/4545, A61K31/422
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/21]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:1-(5-(TERT.-BUTYL)ISOXAZOL-3-YL)-3-(4-((PHENYL)ETHYNYL)PHENYL)HARNSTOFFDERIVATE UND VERWANDTE VERBINDUNGEN ALS FLT3 INHIBITOREN ZUR BEHANDLUNG VON KREBS[2019/18]
English:1-(5-(TERT.-BUTYL)ISOXAZOL-3-YL)-3-(4-((PHENYL)ETHYNYL)PHENYL)UREA DERIVATIVES AND RELATED COMPOUNDS AS FLT3 INHIBITORS FOR TREATING CANCER[2019/18]
French:DÉRIVÉS DE 1-(5-(TERT.-BUTYL)ISOXAZOL-3-YL)-3-(4-((PHÉNYL)ÉTHYNYL)PHÉNYL)URÉE EN TANT QU'INHIBITEURS DU FLT3 POUR LE TRAITEMENT DU CANCER[2019/18]
Former [2017/21]SUBSTITUIERTE HARNSTOFFDERIVATE UND PHARMAZEUTISCHE VERWENDUNGEN DAVON
Former [2017/21]SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF
Former [2017/21]DÉRIVÉS D'URÉE SUBSTITUÉS ET UTILISATIONS PHARMACEUTIQUES DE CEUX-CI
Entry into regional phase28.11.2016National basic fee paid 
28.11.2016Search fee paid 
28.11.2016Designation fee(s) paid 
28.11.2016Examination fee paid 
Examination procedure28.11.2016Examination requested  [2017/21]
28.11.2016Date on which the examining division has become responsible
05.07.2018Amendment by applicant (claims and/or description)
27.11.2018Despatch of a communication from the examining division (Time limit: M02)
09.01.2019Reply to a communication from the examining division
26.04.2019Communication of intention to grant the patent
26.06.2019Fee for grant paid
26.06.2019Fee for publishing/printing paid
26.06.2019Receipt of the translation of the claim(s)
Opposition(s)03.06.2020No opposition filed within time limit [2020/33]
Fees paidRenewal fee
19.07.2017Renewal fee patent year 03
30.05.2018Renewal fee patent year 04
10.07.2019Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL21.08.2019
AT21.08.2019
CY21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
MC21.08.2019
MK21.08.2019
MT21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SI21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
[2022/32]
Former [2022/28]AL21.08.2019
AT21.08.2019
CY21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
MC21.08.2019
MT21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SI21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2021/15]AL21.08.2019
AT21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
MC21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SI21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/37]AL21.08.2019
AT21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SI21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/36]AL21.08.2019
AT21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/27]AL21.08.2019
AT21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SK21.08.2019
SM21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
PT23.12.2019
IS24.02.2020
Former [2020/25]AL21.08.2019
AT21.08.2019
CZ21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
SK21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
PT23.12.2019
IS24.02.2020
Former [2020/24]AL21.08.2019
AT21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
PT23.12.2019
IS24.02.2020
Former [2020/23]AL21.08.2019
AT21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
PL21.08.2019
RO21.08.2019
RS21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/22]AL21.08.2019
EE21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
RS21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/17]AL21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
RS21.08.2019
TR21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/15]AL21.08.2019
HR21.08.2019
LT21.08.2019
LV21.08.2019
RS21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/12]HR21.08.2019
LT21.08.2019
LV21.08.2019
RS21.08.2019
BG21.11.2019
NO21.11.2019
GR22.11.2019
IS21.12.2019
PT23.12.2019
Former [2020/10]LT21.08.2019
BG21.11.2019
NO21.11.2019
PT23.12.2019
Former [2020/08]LT21.08.2019
NO21.11.2019
Documents cited:Search[A]WO2005060969  (ASTRAZENECA AB [SE], et al) [A] 1-16 * claim 1 * * page 86, line 27 - page 87, line 4 *;
 [A]WO2005060970  (ASTRAZENECA AB [SE], et al) [A] 1-16 * claim 1 * * page 86, line 29 - page 87, line 6 *;
 [I]WO2006082404  (ASTRAZENECA AB [SE], et al) [I] 1-16 * claim 1 * * page 84 - page 93; examples 1-13 * * page 77, line 16 - line 26 *;
 [A]US2013274274  (KIM HONG WOO [US], et al) [A] 1-16* claims 1, 12 *
International search[A]WO2005060969  (ASTRAZENECA AB [SE], et al) [A] 1-21 , 25-28 * the whole document *;
 [A]WO2005060970  (ASTRAZENECA AB [SE], et al) [A] 1-21, 25-28* the whole document *;
 [A]WO2006082404  (ASTRAZENECA AB [SE], et al) [A] 1-21, 25-28 * the whole document *
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