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Extract from the Register of European Patents

EP About this file: EP4058486

EP4058486 - ANTIBODY-PAYLOAD CONJUGATES WITH ENHANCED DELIVERY DOMAIN AND USES THEREOF [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  19.08.2022
Database last updated on 25.09.2024
FormerThe international publication has been made
Status updated on  21.05.2021
Most recent event   Tooltip24.01.2024The date on which the examining division becomes responsible, has been established 
24.01.2024Amendment by applicant 
Applicant(s)For all designated states
Iprogen Biotech Inc.
8531 Commerce Crt.
Burnaby, British Columbia V5A 4N4 / CA
[2022/38]
Inventor(s)01 / LEE, Keun Ho
2270 Stanwood Avenue
Coquitlam, British Columbia V3K 3A6 / CA
02 / LIN, Leo Yen-Cheng
16618 79A Avenue
Surrey, British Columbia V4N 0H9 / CA
03 / VAIDYANATHAN, Ranjani
907 - 725 West 70th Avenue
Vancouver, British Columbia V6P 2X3 / CA
04 / LARIO, Paula
201 - 2080 East Kent Ave South
Vancouver, British Columbia V5P 4X2 / CA
 [2022/38]
Representative(s)Wilson, Justin Scott
Withers & Rogers LLP
2 London Bridge
London SE1 9RA / GB
[2022/38]
Application number, filing date19952147.712.11.2019
[2022/38]
WO2019CA51612
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021092672
Date:20.05.2021
Language:EN
[2021/20]
Type: A1 Application with search report 
No.:EP4058486
Date:21.09.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 20.05.2021 takes the place of the publication of the European patent application.
[2022/38]
Search report(s)International search report - published on:CA20.05.2021
(Supplementary) European search report - dispatched on:EP17.07.2023
ClassificationIPC:C07K14/47, C07K19/00, A61K47/68, A61P31/00, A61P35/00, A61P37/06, A61K47/64, C07K16/28, C07K16/32, C07K16/30
[2023/33]
CPC:
A61P31/00 (EP); C07K16/28 (EP,US); A61K47/64 (EP,US);
A61K47/68 (US); A61P35/00 (EP); A61P37/02 (US);
A61P37/06 (EP); C07K14/4723 (EP); C07K16/2803 (EP);
C07K16/2863 (EP); C07K16/2887 (EP); C07K16/30 (EP);
C07K16/3007 (EP); C07K16/32 (EP); C07K2317/622 (EP);
C07K2317/64 (EP,US); C07K2319/30 (EP); C07K2319/735 (EP) (-)
Former IPC [2022/38]C07K19/00, A61K47/68, A61P31/00, A61P35/00, A61P37/06
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/38]
TitleGerman:ANTIKÖRPER-NUTZLAST-KONJUGATE MIT VERBESSERTER ABGABEDOMÄNE UND DEREN VERWENDUNGEN[2022/38]
English:ANTIBODY-PAYLOAD CONJUGATES WITH ENHANCED DELIVERY DOMAIN AND USES THEREOF[2022/38]
French:CONJUGUÉS ANTICORPS-CHARGE UTILE AYANT UN DOMAINE D'ADMINISTRATION AMÉLIORÉ ET LEURS UTILISATIONS[2022/38]
Entry into regional phase09.06.2022National basic fee paid 
09.06.2022Search fee paid 
09.06.2022Designation fee(s) paid 
09.06.2022Examination fee paid 
Examination procedure09.06.2022Examination requested  [2022/38]
23.01.2024Amendment by applicant (claims and/or description)
23.01.2024Date on which the examining division has become responsible
Fees paidRenewal fee
09.06.2022Renewal fee patent year 03
15.09.2022Renewal fee patent year 04
15.11.2023Renewal fee patent year 05
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Documents cited:Search[A]WO2009018500  (UNIV JOHNS HOPKINS [US], et al) [A] 1-15* Whole document, especially the claims. *;
 [A]WO2010129033  (CALMUNE CORP [US], et al) [A] 1-15 * Whole document, especially the claims. *;
 [A]WO2018169953  (SCHERER TECHNOLOGIES LLC R P [US]) [A] 1-15 * Whole document, especially §0228 and claims. *;
 [A]  - XUEJING YAO ET AL, "A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity", BREAST CANCER RESEARCH AND TREATMENT, New York, (20150808), vol. 153, no. 1, doi:10.1007/s10549-015-3503-3, ISSN 0167-6806, pages 123 - 133, XP055370764 [A] 1-15 * Whole document, especially the figures. *

DOI:   http://dx.doi.org/10.1007/s10549-015-3503-3
 [A]  - LI X ET AL, "Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, (20060503), vol. 128, no. 17, doi:10.1021/JA0584875, ISSN 0002-7863, pages 5776 - 5785, XP002410495 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1021/ja0584875
 [A]  - KURODA KENGO ET AL, "The Human Cathelicidin Antimicrobial Peptide LL-37 and Mimics are Potential Anticancer Drugs", FRONTIERS IN ONCOLOGY, (20150630), vol. 5, doi:10.3389/fonc.2015.00144, XP055822431 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.3389/fonc.2015.00144
 [A]  - TANG XIAO ET AL, "P2X7 Receptor Regulates Internalization of Antimicrobial Peptide LL-37 by Human Macrophages That Promotes Intracellular Pathogen Clearance", THE JOURNAL OF IMMUNOLOGY, US, (20150801), vol. 195, no. 3, doi:10.4049/jimmunol.1402845, ISSN 0022-1767, pages 1191 - 1201, XP093059920 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.4049/jimmunol.1402845
International search[XY]WO2009018500  (UNIV JOHNS HOPKINS [US], et al) [X] 1-35,37-47 *[00290], [0338], [0487], [0523]-[0555] * [Y] 36;
 [Y]  - YAO, X. et al., "A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity", Breast Cancer Research and Treatment, (20150818), vol. 153, no. 1, doi:10.1007/s10549-015-3503-3, ISSN 01676806, pages 123 - 133, XP055370764 [Y] 36 *Whole document *

DOI:   http://dx.doi.org/10.1007/s10549-015-3503-3
 [A]  - KURODA, K. et al., "The human cathelicidin antimicrobial peptide LL-37 and mimics are potential anticancer drugs", Frontiers in Oncology, (20150630), vol. 5, no. 144, ISSN 2234943X, pages 1 - 10, XP055822431 [A] 1-47 *Whole document *

DOI:   http://dx.doi.org/10.3389/fonc.2015.00144
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