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Extract from the Register of European Patents

EP About this file: EP1385532

EP1385532 - STIMULATION OF OSTEOGENESIS USING RANK LIGAND FUSION PROTEINS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  04.03.2005
Database last updated on 22.01.2025
Most recent event   Tooltip04.03.2005Withdrawal of applicationpublished on 20.04.2005  [2005/16]
Applicant(s)For all designated states
Barnes-Jewish Hospital
216 South Kingshighway, P.O. Box 14109
St. Louis, MO 63178 / US
[N/P]
Former [2004/06]For all designated states
Barnes-Jewish Hospital
216 South Kingshighway, P.O. Box 14109
St. Louis, MO 63178 / US
Inventor(s)01 / LAM, Jonathan
Barnes-Jewish Hospital, 216 S. Kingshighway
PO Box 14109, St. Louis, MO 63178 / US
02 / ROSS, F., Patrick
Barnes-Jewish Hospital, 216 S. Kingshighway
P.O. Box 14109, St. Louis, MO 63178 / US
03 / TEITELBAUM, Steven, L.
Barnes-Jewish Hospital, 216 S. Kingshighway
P.O. Box 14109, St. Louis, MO 63178 / US
 [2004/06]
Representative(s)Mercer, Christopher Paul, et al
Carpmaels & Ransford LLP
One Southampton Row
London
WC1B 5HA / GB
[N/P]
Former [2004/06]Mercer, Christopher Paul, et al
Carpmaels & Ransford 43, Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date02741650.222.03.2002
[2004/06]
WO2002US09271
Priority number, dateUS20010277855P22.03.2001         Original published format: US 277855 P
US20010311163P09.08.2001         Original published format: US 311163 P
US20010328876P12.10.2001         Original published format: US 328876 P
US20010329231P12.10.2001         Original published format: US 329231 P
US20010329393P15.10.2001         Original published format: US 329393 P
[2004/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO02080955
Date:17.10.2002
Language:EN
[2002/42]
Type: A1 Application with search report 
No.:EP1385532
Date:04.02.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 17.10.2002 takes the place of the publication of the European patent application.
[2004/06]
Search report(s)International search report - published on:US17.10.2002
(Supplementary) European search report - dispatched on:EP28.10.2004
ClassificationIPC:A61K38/00, C07K14/00, A61K38/16, A61P19/08
[2004/51]
CPC:
G01N33/6863 (EP); A61K38/1709 (EP); A61P1/02 (EP);
A61P19/00 (EP); A61P19/02 (EP); A61P19/08 (EP);
A61P19/10 (EP); A61P29/00 (EP); A61P3/14 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P5/38 (EP);
A61P7/00 (EP); C07K14/70575 (EP); C12Q1/42 (EP);
C12Q1/485 (EP); C07K2319/00 (EP); G01N2500/10 (EP) (-)
C-Set:
A61K38/1709, A61K2300/00 (EP)
Former IPC [2004/06]A61K38/00, C07K14/00
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/06]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:STIMULATION DER OSTEOGENESE MIT RANG-LIGANDENFUSIONSPROTEINEN[2004/06]
English:STIMULATION OF OSTEOGENESIS USING RANK LIGAND FUSION PROTEINS[2004/06]
French:STIMULATION D'OSTEOGENESE UTILISANT DES PROTEINES DE FUSION DE LIGANDS RANK[2004/06]
Entry into regional phase22.10.2003National basic fee paid 
22.10.2003Search fee paid 
22.10.2003Designation fee(s) paid 
22.10.2003Examination fee paid 
Examination procedure03.10.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
22.10.2003Amendment by applicant (claims and/or description)
22.10.2003Examination requested  [2004/06]
24.02.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
28.02.2005Application withdrawn by applicant  [2005/16]
Fees paidRenewal fee
22.10.2003Renewal fee patent year 03
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Documents cited:Search[X]WO9958674  (IMMUNEX CORP [US], et al) [X] 57-64,69-74,78-89,93-95 * examples 2,3 *;
 [X]WO0015807  (M & E BIOTECH A S [DK], et al) [X] 1-95 * page 5, line 16 - line 24 * * page 10, line 19 - line 26 * * page 18, line 11 - line 26 *;
 [XP]WO0142298  (KORNBLUTH RICHARD S [US]) [XP] 57-64,69-74,78-89,93-95 * page 7, line 29 - page 8, line 12 * * page 20; table 1 *;
 [XP]  - LAM J ET AL, RANK ligand stimulates anabolic bone formation, TWENTY-THIRD ANNUAL MEETING OF THE AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH; PHOENIX, ARIZONA, USA; OCTOBER 12-16, 2001, JOURNAL OF BONE AND MINERAL RESEARCH, VOL. 16, NR. SUPPL. 1, PAGE(S) S150, (200109), ISSN 0884-0431, XP009038403 [XP] 1-95 * abstract *
 [A]  - LACEY D L ET AL, "Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation", CELL, CELL PRESS, CAMBRIDGE, NA, US, (19980417), vol. 93, no. 2, ISSN 0092-8674, pages 165 - 176, XP002117567 [A] 1-95 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0092-8674(00)81569-X
 [A]  - KONG Y-Y ET AL, "Osteoprotegerin ligand: a regulator of immune responses and bone physiology", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, (20001001), vol. 21, no. 10, ISSN 0167-5699, pages 495 - 502, XP004217459 [A] 1-95 * page 495 *

DOI:   http://dx.doi.org/10.1016/S0167-5699(00)01718-7
International search[X]US6017729  (ANDERSON DIRK M [US]);
 [A]  - O'BRIEN E.A. ET AL., "Osteoprotegrin ligand regulates osteoclast adherence to the bone surface in mouse calvaria", BIOCHEM. BIOPHYS. RES. COMM., (2000), vol. 274, no. 2, pages 281 - 290, XP002955258

DOI:   http://dx.doi.org/10.1006/bbrc.2000.3129
 [X]  - JAISWAL R.K. ET AL., "Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase", J. BIOL. CHEM., (2000), vol. 275, no. 13, pages 9645 - 9652, XP002955257

DOI:   http://dx.doi.org/10.1074/jbc.275.13.9645
 [Y]  - RODAN G.A. ET AL., "Therapeutic approaches to bone diseases", SCIENCE, (2000), vol. 289, pages 1508 - 1514, XP002955256

DOI:   http://dx.doi.org/10.1126/science.289.5484.1508
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.