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Extract from the Register of European Patents

EP About this file: EP1435787

EP1435787 - NESTIN-EXPRESSING HAIR FOLLICLE STEM CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  28.09.2012
Database last updated on 22.01.2025
Most recent event   Tooltip18.04.2014Lapse of the patent in a contracting state
New state(s): TR		published on 21.05.2014  [2014/21]
Applicant(s)For all designated states
AntiCancer, Inc.
7917 Ostrow Street
San Diego, CA 92111-3604 / US
[N/P]
Former [2004/29]For all designated states
Anticancer, Inc.
7917 Ostrow Street
San Diego, CA 92111-3604 / US
Inventor(s)01 / LI, Lingna
4469 Longshore Way
San Diego, CA 92130 / US
02 / YANG, Meng
9115 Truman Street
San Diego, CA 92129 / US
 [2011/47]
Former [2004/29]01 / LI, Lingna
4469 Longshore Way
San Diego, CA 92130 / US
02 / YANG, Meng
Apt. 2105, 12631 El Camino Real
San Diego, CA 92130 / US
Representative(s)Fisher, Adrian John, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2009/51]Fisher, Adrian John, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2004/29]Fisher, Adrian John, et al
Carpmaels & Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date02773519.020.09.2002
[2004/29]
WO2002US30027
Priority number, dateUS20010323963P20.09.2001         Original published format: US 323963 P
[2004/29]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO03024406
Date:27.03.2003
Language:EN
[2003/13]
Type: A2 Application without search report 
No.:EP1435787
Date:14.07.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 27.03.2003 takes the place of the publication of the European patent application.
[2004/29]
Type: B1 Patent specification 
No.:EP1435787
Date:23.11.2011
Language:EN
[2011/47]
Search report(s)International search report - published on:US04.12.2003
(Supplementary) European search report - dispatched on:EP19.10.2004
ClassificationIPC:C12N5/074, C12N5/0775
[2011/47]
CPC:
C12N5/0661 (EP,US); C12N5/06 (KR); A61P1/16 (EP);
A61P17/00 (EP); A61P17/02 (EP); A61P17/14 (EP);
A61P25/00 (EP); A61P25/16 (EP); A61P25/28 (EP);
A61P9/00 (EP); C12N5/00 (KR); C12N5/0602 (KR);
C12N5/0619 (EP,US); C12N5/0622 (EP,US); C12N5/0628 (EP,US);
A61K35/12 (EP,US); C12N2501/13 (EP,US); C12N2501/135 (EP,US);
C12N2506/092 (EP,US) (-)
Former IPC [2004/46]C12N5/06
Former IPC [2004/29]A01N63/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   SK,   TR [2004/29]
TitleGerman:NESTINEXPRIMIERENDE HAARFOLLIKELSTAMMZELLEN[2004/29]
English:NESTIN-EXPRESSING HAIR FOLLICLE STEM CELLS[2004/29]
French:CELLULES SOUCHES DE FOLLICULES PILEUX EXPRIMANT LA NESTINE[2004/29]
Entry into regional phase16.04.2004National basic fee paid 
16.04.2004Search fee paid 
16.04.2004Designation fee(s) paid 
16.04.2004Examination fee paid 
Examination procedure16.04.2004Amendment by applicant (claims and/or description)
16.04.2004Examination requested  [2004/29]
09.02.2006Despatch of a communication from the examining division (Time limit: M06)
18.08.2006Reply to a communication from the examining division
13.12.2007Despatch of a communication from the examining division (Time limit: M06)
23.06.2008Reply to a communication from the examining division
21.01.2010Despatch of a communication from the examining division (Time limit: M04)
24.05.2010Reply to a communication from the examining division
30.09.2010Despatch of a communication from the examining division (Time limit: M04)
10.02.2011Reply to a communication from the examining division
28.04.2011Communication of intention to grant the patent
08.08.2011Fee for grant paid
08.08.2011Fee for publishing/printing paid
Divisional application(s)EP10180320.3  / EP2287290
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.02.2006
Opposition(s)24.08.2012No opposition filed within time limit [2012/44]
Fees paidRenewal fee
16.04.2004Renewal fee patent year 03
14.09.2005Renewal fee patent year 04
11.09.2006Renewal fee patent year 05
12.09.2007Renewal fee patent year 06
31.03.2008Renewal fee patent year 07
11.09.2009Renewal fee patent year 08
14.09.2010Renewal fee patent year 09
29.09.2011Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.11.2011
CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
FI23.11.2011
IT23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
TR23.11.2011
BG23.02.2012
GR24.02.2012
ES05.03.2012
PT23.03.2012
[2014/21]
Former [2013/29]AT23.11.2011
CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
FI23.11.2011
IT23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
BG23.02.2012
GR24.02.2012
ES05.03.2012
PT23.03.2012
Former [2013/22]AT23.11.2011
CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
IT23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
BG23.02.2012
GR24.02.2012
ES05.03.2012
PT23.03.2012
Former [2013/07]AT23.11.2011
CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
IT23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
BG23.02.2012
GR24.02.2012
PT23.03.2012
Former [2012/37]CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
IT23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
BG23.02.2012
GR24.02.2012
PT23.03.2012
Former [2012/36]CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
NL23.11.2011
SE23.11.2011
SK23.11.2011
BG23.02.2012
GR24.02.2012
PT23.03.2012
Former [2012/35]CY23.11.2011
CZ23.11.2011
DK23.11.2011
EE23.11.2011
NL23.11.2011
SE23.11.2011
BG23.02.2012
GR24.02.2012
PT23.03.2012
Former [2012/34]CY23.11.2011
CZ23.11.2011
NL23.11.2011
SE23.11.2011
GR24.02.2012
PT23.03.2012
Former [2012/28]CY23.11.2011
NL23.11.2011
SE23.11.2011
GR24.02.2012
PT23.03.2012
Former [2012/24]NL23.11.2011
SE23.11.2011
GR24.02.2012
PT23.03.2012
Former [2012/23]NL23.11.2011
GR24.02.2012
PT23.03.2012
Documents cited:Search[A]WO9501423  (UNIV PENNSYLVANIA [US], et al) [A] 1-19 * the whole document *;
 [PX]WO0240645  (DAIG ROSEMARIE [DE]) [PX] 1-19 * the whole document *;
 [X]  - TOMA J G ET AL, "ISOLATION OF MULTIPOTENT ADULT STEM CELLS FROM THE DERMIS OF MAMMALIAN SKIN", NATURE CELL BIOLOGY, MACMILLAN PUBLISHERS, GB, (20010813), vol. 3, ISSN 1465-7392, pages 778 - 784, XP001022251 [X] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1038/ncb0901-778
 [X]  - LAKO LINDA ET AL, "Cells of the dermal sheath and dermal papilla possess haematopoietic potential", DEVELOPMENT GROWTH AND DIFFERENTIATION, & 14TH INTERNATIONAL CONGRESS OF DEVELOPMENTAL BIOLOGY; KYOTO, JAPAN; JULY 08-12, 2001, (200107), vol. 43, no. Supplement, ISSN 0012-1592, page S22, XP002296954 [X] 1-19 * the whole document *
 [T]  - LAKO MAJLINDA ET AL, "Hair follicle dermal cells repopulate the mouse haematopoietic system.", JOURNAL OF CELL SCIENCE. 15 OCT 2002, (20021015), vol. 115, no. Pt 20, ISSN 0021-9533, pages 3967 - 3974, XP002296955 [T] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1242/jcs.00060
 [X]  - TANI HIROAKI ET AL, "Enrichment for murine keratinocyte stem cells based on cell surface phenotype", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (20000926), vol. 97, no. 20, ISSN 0027-8424, pages 10960 - 10965, XP002208441 [X] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.97.20.10960
 [X]  - LYLE S ET AL, "The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells.", JOURNAL OF CELL SCIENCE. NOV 1998, (199811), vol. 111 ( Pt 21), ISSN 0021-9533, pages 3179 - 3188, XP002296956 [X] 1-6 * the whole document *
 [XA]  - BICKENBACH J R ET AL, "Epidermal stem cells: characteristics and use in tissue engineering and gene therapy.", ADVANCES IN DERMATOLOGY. 2000, (2000), vol. 16, ISSN 0882-0880, pages 159 - 183 ; dis, XP009036662 [X] 1-5 * the whole document * [A] 6-19
 [A]  - OSHIMA H ET AL, "Morphogenesis and renewal of hair follicles from adult multipotent stem cells", CELL, CELL PRESS, CAMBRIDGE, NA, US, (20010126), vol. 104, ISSN 0092-8674, pages 233 - 245, XP002964136 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0092-8674(01)00208-2
 [T]  - LI LINGNA ET AL, "Nestin expression in hair follicle sheath progenitor cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 19 AUG 2003, (20030819), vol. 100, no. 17, ISSN 0027-8424, pages 9958 - 9961, XP002296957 [T] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.1733025100
 [T]  - AMOH YASUYUKI ET AL, "Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 7 SEP 2004, (20040907), vol. 101, no. 36, ISSN 0027-8424, pages 13291 - 13295, XP002296958 [T] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0405250101
International search[X]  - REYNOLDS ET AL., "Hair follicle stem cells? A distinct germinative epidermal cell populuation is activated in vitro by the presence of hair dermal papilla cells", JOURNAL OF CELL SCIENCE, (1991), vol. 99, pages 373 - 385, XP001010318
 [A]  - OSHIMA ET AL., "Morphogenesis and renewal of hair follicles from adult multipotent stem cells", CELL, (200101), vol. 104, pages 233 - 245, XP002964136

DOI:   http://dx.doi.org/10.1016/S0092-8674(01)00208-2
by applicant   - MEZEY, E. ET AL., SCIENCE, (2000), vol. 290, pages 1779 - 1782
    - BRAZELTON, T.R. ET AL., SCIENCE, (2000), vol. 290, pages 1775 - 1779
    - JIANG, Y. ET AL., NATURE, (2002), vol. 418, pages 41 - 49
    - KRAUSE, D.S. ET AL., CELL, (2001), vol. 105, pages 369 - 377
    - LAGASSE, E. ET AL., NAT. MED., (2000), vol. 6, pages 1229 - 1234
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.