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Extract from the Register of European Patents

EP About this file: EP1689383

EP1689383 - NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.09.2013
Database last updated on 23.04.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Metabasis Therapeutics, Inc.
11085 North Torrey Pines Road Suite 300
La Jolla, CA 92037 / US
[2010/25]
Former [2006/33]For all designated states
Metabasis Therapeutics, Inc.
11119 North Torrey Pines Road
La Jolla CA 92037 / US
Inventor(s)01 / ERION, Mark, D.
13455 Mango Drive
Del Mar, CA 92104 / US
02 / JIANG, Hongjian
13106 Sierra Mesa Road
San Diego, CA 92129 / US
03 / BOYER, Serge, H.
5112 Castle Hills Drive
San Diego, CA 92109 / US
 [2006/33]
Representative(s)Uexküll & Stolberg
Partnerschaft von
Patent- und Rechtsanwälten mbB
Beselerstraße 4
22607 Hamburg / DE
[N/P]
Former [2012/44]UEXKÜLL & STOLBERG
Patentanwälte
Beselerstrasse 4
22607 Hamburg / DE
Former [2009/24]UEXKÜLL & STOLBERG
Patentanwälte Beselerstrasse 4
22607 Hamburg / DE
Former [2007/43]Savic, Bojan
Fleuchaus & Gallo Patent- und Rechtsanwälte Melchiorstraße 42
81479 München / DE
Former [2006/33]Viering, Jentschura & Partner
Postfach 22 14 43
80504 München / DE
Application number, filing date04811701.419.11.2004
[2006/33]
WO2004US39024
Priority number, dateUS20030523830P19.11.2003         Original published format: US 523830 P
US20040598524P03.08.2004         Original published format: US 598524 P
[2006/33]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2005051298
Date:09.06.2005
Language:EN
[2005/23]
Type: A2 Application without search report 
No.:EP1689383
Date:16.08.2006
Language:EN
The application published by WIPO in one of the EPO official languages on 09.06.2005 takes the place of the publication of the European patent application.
[2006/33]
Type: B1 Patent specification 
No.:EP1689383
Date:31.10.2012
Language:EN
[2012/44]
Search report(s)International search report - published on:US11.08.2005
(Supplementary) European search report - dispatched on:EP21.01.2009
ClassificationIPC:C07F9/30, A61K31/28, A61K31/445, A61K31/435, C07F9/06, A61P5/18
[2009/08]
CPC:
C07F9/4056 (EP,US); C07F9/06 (KR); A61K31/28 (KR);
A61K31/435 (KR); A61P1/16 (EP); A61P19/10 (EP);
A61P25/24 (EP); A61P27/06 (EP); A61P3/00 (EP);
A61P3/04 (EP); A61P3/06 (EP); A61P3/10 (EP);
A61P35/00 (EP); A61P43/00 (EP); A61P5/14 (EP);
A61P5/18 (EP); A61P9/04 (EP); A61P9/06 (EP);
A61P9/10 (EP); A61P9/12 (EP); C07F9/00 (KR);
C07F9/301 (EP,US); C07F9/306 (EP,US); C07F9/3808 (EP,US);
C07F9/3882 (EP,US); C07F9/4006 (EP,US); C07F9/4075 (EP,US);
C07F9/4407 (EP,US); C07F9/4465 (EP,US); C07F9/5728 (EP,US);
C07F9/58 (EP,US); C07F9/65517 (EP,US); C07F9/657181 (EP,US) (-)
Former IPC [2006/33]A61K31/28, A61K31/445, A61K31/435, C07F9/06
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LU,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2006/33]
Extension statesAL19.06.2006
HR19.06.2006
LT19.06.2006
LV19.06.2006
MK19.06.2006
YU19.06.2006
TitleGerman:NEUE PHOSPHOR ENTHALTENDE THYROMIMETIKA[2006/33]
English:NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS[2006/33]
French:NOUVELLES SUBSTANCES THYROMIMETIQUES CONTENANT DU PHOSPHORE[2006/33]
Entry into regional phase12.06.2006National basic fee paid 
12.06.2006Search fee paid 
12.06.2006Designation fee(s) paid 
12.06.2006Examination fee paid 
Examination procedure12.06.2006Amendment by applicant (claims and/or description)
12.06.2006Examination requested  [2006/33]
03.12.2009Despatch of a communication from the examining division (Time limit: M06)
23.07.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
01.10.2010Reply to a communication from the examining division
30.01.2012Cancellation of oral proceeding that was planned for 31.01.2012
31.01.2012Date of oral proceedings (cancelled)
27.03.2012Communication of intention to grant the patent
05.06.2012Fee for grant paid
05.06.2012Fee for publishing/printing paid
Divisional application(s)EP11192434.6  / EP2428516
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.12.2009
Opposition(s)01.08.2013No opposition filed within time limit [2013/41]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
01.10.2010Request for further processing filed
01.10.2010Full payment received (date of receipt of payment)
Request granted
10.02.2011Decision despatched
Fees paidRenewal fee
12.06.2006Renewal fee patent year 03
27.11.2007Renewal fee patent year 04
25.11.2008Renewal fee patent year 05
12.11.2009Renewal fee patent year 06
24.11.2010Renewal fee patent year 07
23.11.2011Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.11.2004
AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
TR31.10.2012
IE19.11.2012
LU19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
MC30.11.2012
FR02.01.2013
BG31.01.2013
GB31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
[2014/34]
Former [2014/27]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
TR31.10.2012
IE19.11.2012
LU19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
MC30.11.2012
FR02.01.2013
BG31.01.2013
GB31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
Former [2014/21]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
TR31.10.2012
IE19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
MC30.11.2012
FR02.01.2013
BG31.01.2013
GB31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
Former [2013/51]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
IE19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
FR02.01.2013
BG31.01.2013
GB31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
Former [2013/50]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
IE19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
FR02.01.2013
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
Former [2013/48]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
IE19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
DE01.06.2013
Former [2013/47]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
IE19.11.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/37]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
IT31.10.2012
NL31.10.2012
PL31.10.2012
RO31.10.2012
SI31.10.2012
SK31.10.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/35]AT31.10.2012
BE31.10.2012
CY31.10.2012
CZ31.10.2012
DK31.10.2012
EE31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
SK31.10.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/34]AT31.10.2012
BE31.10.2012
CY31.10.2012
DK31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
SE20.11.2012
CH30.11.2012
LI30.11.2012
BG31.01.2013
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/33]AT31.10.2012
BE31.10.2012
CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
CH30.11.2012
LI30.11.2012
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/31]AT31.10.2012
BE31.10.2012
CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/28]BE31.10.2012
CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
GR01.02.2013
ES11.02.2013
IS28.02.2013
PT28.02.2013
Former [2013/26]BE31.10.2012
CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
SI31.10.2012
GR01.02.2013
ES11.02.2013
IS28.02.2013
Former [2013/24]BE31.10.2012
CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
GR01.02.2013
ES11.02.2013
IS28.02.2013
Former [2013/23]CY31.10.2012
FI31.10.2012
NL31.10.2012
PL31.10.2012
ES11.02.2013
IS28.02.2013
Former [2013/22]FI31.10.2012
NL31.10.2012
ES11.02.2013
IS28.02.2013
Documents cited:Search[PX]WO2004093799  (SQUIBB BRISTOL MYERS CO [US], et al) [PX] 1,2,43,48* examples 166,167; claim - *;
 [X]  - LACOSTE A M ET AL, "Synthèse er propriétés biologiques de l'analogue phosphonique de la thyroxine - Synthesis and biological properties of the phosphonic analog of thyroxine", COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L'ACADEMIE DESSCIENCES. SERIES D, SCIENCES NATURELLES, GAUTHIER-VILLARS, PARIS, FR, (19681125), vol. 267, no. 22, ISSN 0567-655X, pages 1890 - 1892, XP009074723 [X] 1,2,13,16,43,48 * page 1890 - page 1892 *
 [X]  - LACOSTE A M ET AL, "Recherches sur les acides aminoalkylphosphoniques. II. Dérivés iodés de l'analogue phosphonique de la tyrosine - Research on aminoalkylphosphonic acids. II. Iodine derivatives of the phosphonic analogue of tyrosine", BULLETIN DE LA SOCIETE DE CHIMIE BIOLOGIGUE, MASSON, PARIS, FR, (19670101), vol. 49, no. 12, ISSN 0037-9042, pages 1827 - 1835, XP009074724 [X] 1,2,13,16,43,48 * page 1827 - page 1829 *
International search[X]US6465687  (LI YI-LIN [SE], et al);
 [X]US3357887  (FRED KAGAN, et al)
by applicantUS3357877
 US6465687
 WO2004093799
    - OH ET AL., J. NUTR., (1995), vol. 125, no. 1, pages 112 - 24
    - OH ET AL., PROC. SOC. EXP. BIOL. MED., (1994), vol. 207, no. 3, pages 260 - 7
    - UNDERWOOD ET AL., NATURE, (1986), vol. 324, pages 425 - 9
    - STANTON ET AL., BIOORG. MED. CHEM. LETT., (2000), vol. 10, no. 15, pages 1661 - 3
    - DOW ET AL., BIOORG. MED. CHEM. LETT., (2003), vol. 13, no. 3, pages 379 - 82
    - DE BRUIN ET AL., J. CLIN. ENDO. METAB., (1993), vol. 76, pages 121 - 126
    - LACOSTE ET AL., BULL. SOC. CHIM. BIOL., (1967), vol. 49, no. 12, pages 1827 - 35
    - LACOSTE, C.R. ACAD. SC. PARIS, SERIE D, (1968), vol. 267, no. 22, pages 1890 - 2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.