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Extract from the Register of European Patents

EP About this file: EP1866824

EP1866824 - SYSTEM AND METHOD FOR PREDICTION OF DRUG METABOLISM, TOXICITY, MODE OF ACTION, AND SIDE EFFECTS OF NOVEL SMALL MOLECULE COMPOUNDS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  11.09.2015
Database last updated on 28.09.2024
Most recent event   Tooltip11.09.2015Application deemed to be withdrawnpublished on 14.10.2015  [2015/42]
Applicant(s)For all designated states
GeneGo, Inc.
169 Saxony Road, Nr. 104
Encinitas, CA 92024 / US
[2011/04]
Former [2007/51]For all designated states
Ekins, Sean
610 Runnymede Avenue
Jenkintown PA 19046 / US
For all designated states
Bugrim, Andrej
1011 Pearl Street
St. Joseph MI 49085 / US
For all designated states
Nikolskaya, Tatiana
21 Chrismar Road
Portage IN 46368 / US
For all designated states
Nikolsky, Yuri
21 Chrisma Road
Portage IN 46368 / US
Inventor(s)01 / Ekins, Sean
610 Runnymede Avenue
Jenkintown, PA 19046 / US
02 / Bugrim, Andrej
1011 Pearl Street
St. Joseph, MI 49085 / US
03 / Nikolskaya, Tatiana
21 Chrismar Road
Portage, IN 46368 / US
04 / Nikolsky, Yuri
21 Chrisma Road
Portage, IN 46368 / US
 [2011/04]
Former [2007/51]01 / see applicant
...
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[N/P]
Former [2013/51]Boult Wade Tennant
Verulam Gardens
70 Gray's Inn Road
London WC1X 8BT / GB
Former [2009/52]Palmer, Jonathan R.
Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT / GB
Former [2007/51]Palmer, Jonathan R.
Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT / GB
Application number, filing date06748475.817.03.2006
[2007/51]
WO2006US10053
Priority number, dateUS20050662699P17.03.2005         Original published format: US 662699 P
[2007/51]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006099624
Date:21.09.2006
Language:EN
[2006/38]
Type: A2 Application without search report 
No.:EP1866824
Date:19.12.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 21.09.2006 takes the place of the publication of the European patent application.
[2007/51]
Search report(s)International search report - published on:US06.12.2007
(Supplementary) European search report - dispatched on:EP06.07.2009
ClassificationIPC:G06F19/00, G01N33/48, G06G7/48
[2009/31]
CPC:
G16C20/30 (EP); G16B35/00 (GB); G16B20/20 (EP,GB,US);
G16B5/00 (EP,GB,US); G16C20/60 (GB); G16B20/00 (EP);
G16B45/00 (EP); G16C20/80 (EP) (-)
Former IPC [2008/09]G01N33/48, G06G7/48
Former IPC [2007/51]G06F19/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/51]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:SYSTEM UND VERFAHREN ZUR VORHERSAGE DES ARZNEIMITTELMETABOLISMUS, DER TOXIZITÄT, DER WIRKUNGSWEISE UND DER NEBENEFFEKTE NEUER KLEINMOLEKÜLVERBINDUNGEN[2007/51]
English:SYSTEM AND METHOD FOR PREDICTION OF DRUG METABOLISM, TOXICITY, MODE OF ACTION, AND SIDE EFFECTS OF NOVEL SMALL MOLECULE COMPOUNDS[2007/51]
French:SYSTEME ET PROCEDE POUR PREDIRE LE METABOLISME, LA TOXICITE, LE MODE D'ACTION, ET LES EFFETS SECONDAIRES DE NOUVEAUX COMPOSES CONSTITUES DE PETITES MOLECULES CHEZ L'ETRE HUMAIN[2007/51]
Entry into regional phase08.10.2007National basic fee paid 
08.10.2007Search fee paid 
08.10.2007Designation fee(s) paid 
08.10.2007Examination fee paid 
Examination procedure08.10.2007Examination requested  [2007/51]
05.03.2008Amendment by applicant (claims and/or description)
04.11.2009Despatch of a communication from the examining division (Time limit: M06)
01.09.2010Reply to a communication from the examining division
23.12.2014Despatch of a communication from the examining division (Time limit: M04)
05.05.2015Application deemed to be withdrawn, date of legal effect  [2015/42]
01.06.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/42]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.11.2009
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
01.09.2010Request for further processing filed
01.09.2010Full payment received (date of receipt of payment)
Fees paidRenewal fee
25.03.2008Renewal fee patent year 03
06.05.2009Renewal fee patent year 04
31.03.2010Renewal fee patent year 05
06.04.2011Renewal fee patent year 06
07.03.2012Renewal fee patent year 07
08.03.2013Renewal fee patent year 08
10.03.2014Renewal fee patent year 09
06.03.2015Renewal fee patent year 10
Penalty fee
Additional fee for renewal fee
31.03.200904   M06   Fee paid on   06.05.2009
31.03.201106   M06   Fee paid on   06.04.2011
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]  - BUGRIM ANDREJ ET AL, "Early prediction of drug metabolism and toxicity: Systems biology approach and modeling.", DRUG DISCOVERY TODAY, (20040201), vol. 9, no. 3, ISSN 1359-6446, pages 127 - 135, XP002532445 [X] 1-43 * the whole document * * in particular * * page 132, column R, line 20 - page 134, column L, line 21 * * figures 2,3 *

DOI:   http://dx.doi.org/10.1016/S1359-6446(03)02971-4
 [X]  - EKINS S ET AL, "Techniques: Application of systems biology to absorption, distribution, metabolism, excretion and toxicity", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER, HAYWARTH, GB, (20050303), vol. 26, no. 4, ISSN 0165-6147, pages 202 - 209, XP004829254 [X] 1-43 * the whole document * * in particular * * abstract * * page 202, column R, lines 14-41 * * page 204, column L, line 25 - column R, line 6 * * page 205, column L, lines 19-24 * * page 205, column L, lines 52-61 * * page 206, column R, line 11 - page 207, column L, line 23 * * page 207, column L, line 45 - column R, line 9 * * figures 2-4 *

DOI:   http://dx.doi.org/10.1016/j.tips.2005.02.006
 [X]  - EKINS SEAN ET AL, "A novel method for visualizing nuclear hormone receptor networks relevant to drug metabolism.", DRUG METABOLISM AND DISPOSITION: THE BIOLOGICAL FATE OF CHEMICALS MAR 2005, (200503), vol. 33, no. 3, ISSN 0090-9556, pages 474 - 481, XP002532446 [X] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1124/DMD.104.002717
 [A]  - EKINS S, "In silico approaches to predicting drug metabolism, toxicology and beyond.", BIOCHEMICAL SOCIETY TRANSACTIONS, (200306), vol. 31, no. 3, ISSN 0300-5127, pages 611 - 614, XP002532447 [A] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1042/BST0310611
 [A]  - SCOTT BOYER ET AL, "New methods in predictive metabolism", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, KLUWER ACADEMIC PUBLISHERS, DO, (20020501), vol. 16, no. 5-6, ISSN 1573-4951, pages 403 - 413, XP019248057 [A] 1-43 * the whole document *
 [PX]  - EKINS SEAN ET AL, "A combined approach to drug metabolism and toxicity assessment", DRUG METABOLISM AND DISPOSITION, WILLIAMS AND WILKINS, BALTIMORE, MD, US, (20060301), vol. 34, no. 3, ISSN 0090-9556, pages 495 - 503, XP002488587 [PX] 1-43 * the whole document *
 [PX]  - EKINS SEAN ET AL, "Computational prediction of human drug metabolism", EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, ASHLEY PUBLICATIONS, LONDON, GB, (20050801), vol. 1, no. 2, ISSN 1742-5255, pages 303 - 324, XP009091066 [PX] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1517/17425255.1.2.303
 [PX]  - NIKOLSKY Y ET AL, "Biological networks and analysis of experimental data in drug discovery", DRUG DISCOVERY TODAY, ELSEVIER, RAHWAY, NJ, US, (20050501), vol. 10, no. 9, ISSN 1359-6446, pages 653 - 662, XP004890889 [PX] 1-43 * the whole document *

DOI:   http://dx.doi.org/10.1016/S1359-6446(05)03420-3
International search[Y]US6365131  (DOSHI MADHUKANT MANSUKHLAL [IN], et al);
 [Y]  - EKINS ET AL., "Application of three-dimensional quantitative structure-activity relationships of P-Glycoprotein inhibitors and substrates", MOLECULAR PHARMACOLOGY, (2002), vol. 61, no. 5, pages 974 - 981, XP008091584

DOI:   http://dx.doi.org/10.1124/mol.61.5.974
 [Y]  - SCHUETZ ET AL., "Modulators and substrates of P-Glycoprotein and cytochrome P4503A coordinately up-regulate these proteins un human colon carcinoma cells", MOLECULAR PHARMACOLOGY, (1996), vol. 49, no. 2, pages 311 - 318, XP000906895
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.