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Extract from the Register of European Patents

EP About this file: EP1953542

EP1953542 - METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.02.2014
Database last updated on 11.11.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU
published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
TOHOKU UNIVERSITY
1-1 Katahira 2-chome Aoba-ku
Sendai-shi, Miyagi 980-8577 / JP
[2008/32]
Inventor(s)01 / KAMIIE, Junichi
c/o TOHOKU UNIVERSITY,
1-1, Katahira 2-chome
Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
02 / OTSUKI, Sumio
c/o TOHOKU UNIVERSITY,
1-1, Katahira 2-chome
Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
03 / TERASAKI, Tetsuya
c/o TOHOKU UNIVERSITY,
1-1, Katahira 2-chome
Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
 [2013/15]
Former [2008/32]01 / KAMIIE, Junichi
c/o TOHOKU UNIVERSITY, 1-1, Katahira 2-chome, Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
02 / OTSUKI, Sumio
c/o TOHOKU UNIVERSITY, 1-1, Katahira 2-chome, Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
03 / TERASAKI, Tetsuya
c/o TOHOKU UNIVERSITY, 1-1, Katahira 2-chome, Aoba-ku
Sendai-shi, Miyagi 9808577 / JP
Representative(s)Harding, Charles Thomas
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[N/P]
Former [2013/15]Harding, Charles Thomas
D Young & Co LLP 120 Holborn London
EC1N 2DY / GB
Former [2008/32]Harding, Charles Thomas
D Young & Co 120 Holborn
London EC1N 2DY / GB
Application number, filing date06822538.227.10.2006
[2008/32]
WO2006JP321577
Priority number, dateJP2005032415908.11.2005         Original published format: JP 2005324159
[2008/32]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007055116
Date:18.05.2007
Language:JA
[2007/20]
Type: A1 Application with search report 
No.:EP1953542
Date:06.08.2008
Language:EN
[2008/32]
Type: B1 Patent specification 
No.:EP1953542
Date:10.04.2013
Language:EN
[2013/15]
Type: B9 Corrected patent specification 
No.:EP1953542
Date:13.11.2013
[2013/46]
Search report(s)International search report - published on:JP18.05.2007
(Supplementary) European search report - dispatched on:EP23.03.2009
ClassificationIPC:G01N33/68
[2012/25]
CPC:
G01N30/88 (EP,US); G01N33/6848 (EP,KR,US); G01N30/7266 (EP,KR,US);
G01N30/8679 (EP,KR,US); H01J49/00 (EP,KR,US); G01N2030/8813 (EP,KR,US);
G01N2030/8818 (EP,KR,US); G01N2030/8827 (EP,KR,US); G01N2030/8831 (EP,KR,US);
G01N2333/705 (EP,KR,US) (-)
Former IPC [2008/32]G01N27/62, C12Q1/37, G01N30/72, G01N30/88, G01N33/483
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/32]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:VERFAHREN ZUR QUANTIFIZIERUNG EINES MEMBRANPROTEINS UNTER VERWENDUNG EINES MASSENSPEKTROMETERS[2008/32]
English:METHOD OF QUANTIFYING MEMBRANE PROTEIN BY USING MASS SPECTROMETER[2008/32]
French:PROCEDE DE QUANTIFICATION DE PROTEINE MEMBRANAIRE AU MOYEN D'UN SPECTROMETRE DE MASSE[2008/32]
Entry into regional phase05.06.2008Translation filed 
04.06.2008National basic fee paid 
04.06.2008Search fee paid 
04.06.2008Designation fee(s) paid 
04.06.2008Examination fee paid 
Examination procedure07.09.2007Request for preliminary examination filed
International Preliminary Examining Authority: JP
05.06.2008Amendment by applicant (claims and/or description)
05.06.2008Examination requested  [2008/32]
23.06.2009Despatch of a communication from the examining division (Time limit: M04)
03.11.2009Reply to a communication from the examining division
23.11.2010Despatch of a communication from the examining division (Time limit: M04)
23.03.2011Reply to a communication from the examining division
19.04.2012Cancellation of oral proceeding that was planned for 23.04.2012
23.04.2012Date of oral proceedings (cancelled)
06.06.2012Communication of intention to grant the patent
11.10.2012Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
29.10.2012Communication of intention to grant the patent
28.02.2013Fee for grant paid
28.02.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.06.2009
Opposition(s)13.01.2014No opposition filed within time limit [2014/12]
Fees paidRenewal fee
14.10.2008Renewal fee patent year 03
27.10.2009Renewal fee patent year 04
25.10.2010Renewal fee patent year 05
20.10.2011Renewal fee patent year 06
23.10.2012Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.10.2006
AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
IT10.04.2013
LT10.04.2013
LV10.04.2013
MC10.04.2013
NL10.04.2013
PL10.04.2013
RO10.04.2013
SI10.04.2013
SK10.04.2013
TR10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
IE27.10.2013
LU27.10.2013
[2015/34]
Former [2015/32]AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
IT10.04.2013
LT10.04.2013
LV10.04.2013
MC10.04.2013
NL10.04.2013
PL10.04.2013
RO10.04.2013
SI10.04.2013
SK10.04.2013
TR10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
IE27.10.2013
Former [2014/48]AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
IT10.04.2013
LT10.04.2013
LV10.04.2013
MC10.04.2013
NL10.04.2013
PL10.04.2013
RO10.04.2013
SI10.04.2013
SK10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
IE27.10.2013
Former [2014/25]AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
IT10.04.2013
LT10.04.2013
LV10.04.2013
MC10.04.2013
NL10.04.2013
PL10.04.2013
RO10.04.2013
SI10.04.2013
SK10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2014/11]AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
IT10.04.2013
LT10.04.2013
LV10.04.2013
NL10.04.2013
PL10.04.2013
RO10.04.2013
SI10.04.2013
SK10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2014/10]AT10.04.2013
BE10.04.2013
CY10.04.2013
CZ10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
LT10.04.2013
LV10.04.2013
NL10.04.2013
PL10.04.2013
SI10.04.2013
SK10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2014/09]AT10.04.2013
BE10.04.2013
CY10.04.2013
DK10.04.2013
EE10.04.2013
FI10.04.2013
LT10.04.2013
LV10.04.2013
NL10.04.2013
PL10.04.2013
SI10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2013/52]AT10.04.2013
BE10.04.2013
CY10.04.2013
FI10.04.2013
LT10.04.2013
LV10.04.2013
NL10.04.2013
PL10.04.2013
SI10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2013/50]AT10.04.2013
BE10.04.2013
FI10.04.2013
LT10.04.2013
LV10.04.2013
NL10.04.2013
PL10.04.2013
SI10.04.2013
BG10.07.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2013/49]AT10.04.2013
BE10.04.2013
FI10.04.2013
LT10.04.2013
NL10.04.2013
SI10.04.2013
GR11.07.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2013/48]AT10.04.2013
LT10.04.2013
NL10.04.2013
SI10.04.2013
ES21.07.2013
IS10.08.2013
PT12.08.2013
Former [2013/47]LT10.04.2013
SI10.04.2013
PT12.08.2013
Former [2013/37]SI10.04.2013
Documents cited:Search[X]WO03046148  (THERMO FINNIGAN LLC [US], et al) [X] 1-14 * page 8 - page 12; figures 1,2; example 2 *;
 [X]  - BARNIDGE D R ET AL, "Absolute quantification of the G protein-coupled receptor rhodopsin by LC/MS/MS using proteolysis product peptides and synthetic peptide standards", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, (20030201), vol. 75, no. 3, ISSN 0003-2700, pages 445 - 451, XP002360987 [X] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1021/ac026154+
 [T]  - JUNICHI KAMIIE ET AL, "Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, (20080125), vol. 25, no. 6, ISSN 1573-904X, pages 1469 - 1483, XP019613101 [T] 1-14
Examination   - WHITELEGGE J, "Tandem mass spectrometry of integral membrane proteins for top-down proteomics", TRAC, TRENDS IN ANALYTICAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, (20050701), vol. 24, no. 7, doi:10.1016/J.TRAC.2005.04.010, ISSN 0165-9936, pages 576 - 582, XP004988690

DOI:   http://dx.doi.org/10.1016/j.trac.2005.04.010
    - VENTER HENRIETTA ET AL, "Molecular dissection of membrane-transport proteins: Mass spectrometry and sequence determination of the galactose-H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of (ring-2-13C)histidine and 15NH3", BIOCHEMICAL JOURNAL, THE BIOCHEMICAL SOCIETY, LONDON, GB, (20020415), vol. 363, no. 2, doi:10.1042/0264-6021:3630243, ISSN 0264-6021, pages 243 - 252, XP002288523

DOI:   http://dx.doi.org/10.1042/0264-6021:3630243
    - HANS ZISCHKA ET AL, "Improved mass spectrometric identification of gel-separated hydrophobic membrane proteins after sodium dodecyl sulfate removal by ion-pair extraction", PROTEOMICS, (20041201), vol. 4, no. 12, doi:10.1002/pmic.200400851, ISSN 1615-9853, pages 3776 - 3782, XP055009576

DOI:   http://dx.doi.org/10.1002/pmic.200400851
    - S. CLAVEROL, "Characterization of protein variants and post-translational modifications: ESI-MSn analyses of intact proteins eluted from polyacrylamide gels", MOLECULAR & CELLULAR PROTEOMICS, (20030625), doi:10.1074/mcp.T300003-MCP200, ISSN 1535-9476, XP055009578

DOI:   http://dx.doi.org/10.1074/mcp.T300003-MCP200
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