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Extract from the Register of European Patents

EP About this file: EP2155752

EP2155752 - POLYMORPH OF DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVE AS WEEL KINASE.INHIBITOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.07.2019
Database last updated on 22.01.2025
FormerThe patent has been granted
Status updated on  17.08.2018
FormerGrant of patent is intended
Status updated on  11.04.2018
FormerExamination is in progress
Status updated on  09.08.2017
Most recent event   Tooltip23.07.2021Lapse of the patent in a contracting state
New state(s): MT		published on 25.08.2021  [2021/34]
Applicant(s)For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
For all designated states
MSD K.K.
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku Tokyo
102-8667 / JP
[2018/38]
Former [2012/33]For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway NJ 07065-0907 / US
For all designated states
MSD K.K.
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku Tokyo
102-8667 / JP
Former [2011/11]For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
For all designated states
MSD K.K.
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku Tokyo
102-8667 / JP
Former [2010/10]For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Avenue
Rahway, NJ 07065 / US
For all designated states
Banyu Pharmaceutical Co., Ltd.
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
Former [2010/08]For all designated states
Merck & Co., Inc.
126 East Lincoln Avenue
Rahway, NJ 07065-0907 / US
For all designated states
Banyu Pharmaceutical Co., Ltd.
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
Inventor(s)01 / KAWASAKI, Masashi
Kitanomaru Square
1-13-12 Kudankita
Chiyoda-ku
Tokyo 102-8667 / JP
02 / MIZUNO, Hiroo
Kitanomaru Square
1-13-12 Kudankita
Chiyoda-ku
Tokyo 102-8667 / JP
03 / SAKAMOTO, Toshihiro
Kitanomaru Square
1-13-12 Kudankita
Chiyoda-ku
Tokyo 102-8667 / JP
04 / SUZUKI, Kimimasa
Kitanomaru Square
1-13-12 Kudankita
Chiyoda-ku
Tokyo 102-8667 / JP
05 / MCKEOWN, Arlene, E.
126 East Lincoln Avenue
Rahway, New Jersey 07065-0907 / US
 [2018/38]
Former [2010/08]01 / KAWASAKI, Masashi
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
02 / MIZUNO, Hiroo
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
03 / SAKAMOTO, Toshihiro
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
04 / SUZUKI, Kimimasa
Kitanomaru Square 1-13-12 Kudankita Chiyoda-ku
Tokyo 102-8667 / JP
05 / MCKEOWN, Arlene, E.
126 East Lincoln Avenue
Rahway, New Jersey 07065-0907 / US
Representative(s)Potter Clarkson
Chapel Quarter
Mount Street
Nottingham NG1 6HQ / GB
[N/P]
Former [2018/38]Potter Clarkson LLP
The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
Former [2010/08]Hussain, Deeba, et al
Merck & Co., Inc. Hertford Road Hoddesdon
Hertfordshire EN11 9BU / GB
Application number, filing date08743165.622.04.2008
[2010/08]
WO2008US05155
Priority number, dateJP2007011544825.04.2007         Original published format: JP 2007115448
US20070000185P24.10.2007         Original published format: US 185 P
[2010/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008133866
Date:06.11.2008
Language:EN
[2008/45]
Type: A1 Application with search report 
No.:EP2155752
Date:24.02.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 06.11.2008 takes the place of the publication of the European patent application.
[2010/08]
Type: B1 Patent specification 
No.:EP2155752
Date:19.09.2018
Language:EN
[2018/38]
Search report(s)International search report - published on:EP06.11.2008
ClassificationIPC:C07D487/04, A61P35/00, A61K31/519
[2010/08]
CPC:
C07D487/04 (EP,US); A61P35/00 (EP); A61P35/02 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2018/38]
Former [2010/08]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:POLYMORPH EINES DIHYDROPYRAZOLOPYRIMIDINONDERIVATS ALS INHIBITOR DER WEEL-KINASE[2010/08]
English:POLYMORPH OF DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVE AS WEEL KINASE.INHIBITOR[2010/08]
French:POLYMORPHE DE DÉRIVÉ DE DIHYDROPYRAZOLOPYRIMIDINONE COMME INHIBITEUR DE LA KINASE WEEL[2010/08]
Entry into regional phase25.11.2009National basic fee paid 
25.11.2009Designation fee(s) paid 
25.11.2009Examination fee paid 
Examination procedure06.11.2009Amendment by applicant (claims and/or description)
25.11.2009Examination requested  [2010/08]
17.11.2010Despatch of a communication from the examining division (Time limit: M06)
05.07.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
15.09.2011Reply to a communication from the examining division
14.08.2017Despatch of a communication from the examining division (Time limit: M06)
14.02.2018Reply to a communication from the examining division
12.04.2018Communication of intention to grant the patent
13.08.2018Fee for grant paid
13.08.2018Fee for publishing/printing paid
13.08.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.11.2010
Opposition(s)20.06.2019No opposition filed within time limit [2019/35]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
15.09.2011Request for further processing filed
15.09.2011Full payment received (date of receipt of payment)
Request granted
30.09.2011Decision despatched
Fees paidRenewal fee
15.03.2010Renewal fee patent year 03
06.04.2011Renewal fee patent year 04
21.03.2012Renewal fee patent year 05
26.03.2013Renewal fee patent year 06
26.03.2014Renewal fee patent year 07
08.04.2015Renewal fee patent year 08
30.03.2016Renewal fee patent year 09
10.04.2017Renewal fee patent year 10
06.04.2018Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU22.04.2008
AT19.09.2018
CY19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
MT19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
TR19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
IE22.04.2019
LU22.04.2019
BE30.04.2019
[2021/34]
Former [2021/32]HU22.04.2008
AT19.09.2018
CY19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
TR19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
IE22.04.2019
LU22.04.2019
BE30.04.2019
Former [2021/26]AT19.09.2018
CY19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
TR19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
IE22.04.2019
LU22.04.2019
BE30.04.2019
Former [2020/21]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
TR19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
IE22.04.2019
LU22.04.2019
BE30.04.2019
Former [2020/17]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
TR19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU22.04.2019
BE30.04.2019
Former [2020/12]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU22.04.2019
BE30.04.2019
Former [2020/04]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
LU22.04.2019
Former [2020/02]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/49]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
SI19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/34]AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/26]AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/23]AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/22]CZ19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/21]FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/12]FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
Former [2019/11]FI19.09.2018
HR19.09.2018
LT19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
Former [2019/08]FI19.09.2018
LT19.09.2018
NO19.12.2018
Former [2019/07]LT19.09.2018
Cited inInternational search[A]WO03091255  (WARNER LAMBERT CO [US], et al) [A] 1-18 * the whole document *;
 [PX]US2007254892  (SAGARA TAKESHI [JP], et al) [PX] 1-14* page 51; example 53.3 *;
 [PX]WO2007126122  (BANYU PHARMA CO LTD [JP], et al) [PX] 1-14 * page 46 - page 48; example 9 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.