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Extract from the Register of European Patents

EP About this file: EP2318431

EP2318431 - Recombinant pokeweed antiviral proteins, compositions and methods related thereto [Right-click to bookmark this link]
Former [2011/19]RECOMBINANT POKEWEED ANTIVIRAL PROTEINS, COMPOSITIONS AND METHODS RELATED THERETO
[2014/16]
StatusNo opposition filed within time limit
Status updated on  22.01.2016
Database last updated on 21.03.2025
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
Cedus, Inc.
2625 Silver Creek Drive
Fort Collins, CO 80525 / US
For all designated states
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
P.O. Box 483
Fort Collins, CO 80522 / US
[2015/12]
Former [2011/19]For all designated states
Cedus, Inc.
2625 Silver Creek Drive
Fort Collins, CO 80525 / US
For all designated states
Colorado State University Research Foundation
P.O. Box 483
Fort Collins, CO 80521 / US
Inventor(s)01 / WEBER, Eric R.
2625 Silver Creek Drive
Fort Collins, CO 80525 / US
02 / NETT, Torrance M.
5457 Brianna Lane
Bellvue, CO 80521 / US
 [2011/19]
Representative(s)Turner, Craig Robert
Venner Shipley LLP
200 Aldersgate
London EC1A 4HD / GB
[N/P]
Former [2015/12]Turner, Craig Robert
A.A. Thornton & Co.
10 Old Bailey
London EC4M 7NG / GB
Former [2011/19]Turner, Craig Robert
A.A. Thornton & Co. 235 High Holborn
London WC1V 7LE / GB
Application number, filing date09790464.315.07.2009
[2011/19]
WO2009US50685
Priority number, dateUS20080080773P15.07.2008         Original published format: US 80773 P
[2011/19]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010009227
Date:21.01.2010
Language:EN
[2010/03]
Type: A2 Application without search report 
No.:EP2318431
Date:11.05.2011
Language:EN
The application published by WIPO in one of the EPO official languages on 21.01.2010 takes the place of the publication of the European patent application.
[2011/19]
Type: B1 Patent specification 
No.:EP2318431
Date:18.03.2015
Language:EN
[2015/12]
Search report(s)International search report - published on:EP29.04.2010
ClassificationIPC:C07K14/415, C07K19/00, C07K7/23, A61K38/09, C12N1/15, A61K38/00
[2014/16]
CPC:
C07K14/415 (EP,US); A61P31/12 (EP); A61P43/00 (EP);
A61P5/02 (EP); C07K7/23 (EP,US); A61K38/00 (EP,US);
C07K2319/33 (EP,US); C07K2319/55 (EP,US); Y02A50/30 (EP,US) (-)
Former IPC [2011/19]C07K14/415, C07K19/00, C07K7/23, A61K38/09, C12N1/15, C12N1/21, A61P5/02
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2011/19]
TitleGerman:Rekombinante antivirale Proteine aus der Kermesbeere, Zusammensetzungen und zugehörige Verfahren[2014/16]
English:Recombinant pokeweed antiviral proteins, compositions and methods related thereto[2014/16]
French:Protéines antivirales de phytolaque recombinantes, compositions et procédés associés à celles-ci[2014/16]
Former [2011/19]REKOMBINANTE ANTIVIRALE PROTEINE AUS DER KERMESBEERE, ZUSAMMENSETZUNGEN UND ZUGEHÖRIGE VERFAHREN
Former [2011/19]RECOMBINANT POKEWEED ANTIVIRAL PROTEINS, COMPOSITIONS AND METHODS RELATED THERETO
Former [2011/19]PROTÉINES ANTIVIRALES DE PHYTOLAQUE RECOMBINANTES, COMPOSITIONS ET PROCÉDÉS ASSOCIÉS À CELLES-CI
Entry into regional phase04.02.2011National basic fee paid 
04.02.2011Designation fee(s) paid 
04.02.2011Examination fee paid 
Examination procedure04.02.2011Examination requested  [2011/19]
31.03.2011Amendment by applicant (claims and/or description)
10.10.2011Despatch of a communication from the examining division (Time limit: M06)
30.05.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
09.08.2012Reply to a communication from the examining division
05.03.2013Despatch of a communication from the examining division (Time limit: M06)
03.09.2013Reply to a communication from the examining division
16.04.2014Communication of intention to grant the patent
22.08.2014Fee for grant paid
22.08.2014Fee for publishing/printing paid
22.08.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.10.2011
Opposition(s)21.12.2015No opposition filed within time limit [2016/08]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
09.08.2012Request for further processing filed
09.08.2012Full payment received (date of receipt of payment)
Request granted
23.08.2012Decision despatched
Fees paidRenewal fee
25.07.2011Renewal fee patent year 03
25.07.2012Renewal fee patent year 04
29.07.2013Renewal fee patent year 05
02.02.2015Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.07.201406   M06   Fee paid on   02.02.2015
Opt-out from the exclusive  Tooltip
competence of the Unified
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.07.2009
AT18.03.2015
BE18.03.2015
BG18.03.2015
CY18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
MK18.03.2015
MT18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
SM18.03.2015
TR18.03.2015
NO18.06.2015
GR19.06.2015
IE15.07.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
[2018/30]
Former [2017/38]HU15.07.2009
AT18.03.2015
BE18.03.2015
BG18.03.2015
CY18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
MT18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
SM18.03.2015
TR18.03.2015
NO18.06.2015
GR19.06.2015
IE15.07.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
Former [2017/21]AT18.03.2015
BE18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
MT18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IE15.07.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
Former [2016/37]AT18.03.2015
BE18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IE15.07.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
Former [2016/33]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IE15.07.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
Former [2016/22]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
CH31.07.2015
LI31.07.2015
Former [2016/15]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
LU15.07.2015
IS18.07.2015
PT20.07.2015
Former [2016/13]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
MC18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2016/12]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SI18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2016/07]AT18.03.2015
CZ18.03.2015
DK18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2016/03]AT18.03.2015
CZ18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
IT18.03.2015
LT18.03.2015
LV18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2015/51]AT18.03.2015
CZ18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
LT18.03.2015
LV18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2015/50]CZ18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
LT18.03.2015
LV18.03.2015
PL18.03.2015
RO18.03.2015
SE18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
IS18.07.2015
PT20.07.2015
Former [2015/49]CZ18.03.2015
EE18.03.2015
ES18.03.2015
FI18.03.2015
HR18.03.2015
LT18.03.2015
LV18.03.2015
RO18.03.2015
SE18.03.2015
SK18.03.2015
NO18.06.2015
GR19.06.2015
PT20.07.2015
Former [2015/39]FI18.03.2015
HR18.03.2015
LT18.03.2015
LV18.03.2015
SE18.03.2015
NO18.06.2015
GR19.06.2015
Former [2015/37]FI18.03.2015
HR18.03.2015
LT18.03.2015
SE18.03.2015
NO18.06.2015
GR19.06.2015
Former [2015/36]FI18.03.2015
HR18.03.2015
LT18.03.2015
SE18.03.2015
NO18.06.2015
Former [2015/35]LT18.03.2015
NO18.06.2015
Cited inInternational search[A]WO9009799  (UNIV COLORADO STATE RES FOUND [US]) [A] 1-17 * the whole document *;
 [I]US2005277582  (NETT TORRANCE M [US], et al) [I] 1-17 * paragraph [0024] - paragraph [0028] * * paragraph [0042] *;
 [I]  - QI LIN ET AL, "Binding and cytotoxicity of conjugated and recombinant fusion proteins targeted to the gonadotropin-releasing hormone receptor.", CANCER RESEARCH, (20040315), vol. 64, no. 6, ISSN 0008-5472, pages 2090 - 2095, XP002557871 [I] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-3192-2
 [I]  - YANG WEI-HSIUNG ET AL, "Cytotoxic activity of gonadotropin-releasing hormone (GnRH)-pokeweed antiviral protein conjugates in cell lines expressing GnRH receptors.", ENDOCRINOLOGY, (200304), vol. 144, no. 4, ISSN 0013-7227, pages 1456 - 1463, XP002557872 [I] 1-17 * the whole document *

DOI:   http://dx.doi.org/10.1210/en.2002-220917
 [YA]  - CHADDOCK JOHN A ET AL, "Pokeweed antiviral protein (PAP) mutations which permit E. coli growth do not eliminate catalytic activity towards prokaryotic ribosomes", NUCLEIC ACIDS RESEARCH, (1994), vol. 22, no. 9, ISSN 0305-1048, pages 1536 - 1540, XP002557873 [Y] 20-25 * abstract * [A] 1-17

DOI:   http://dx.doi.org/10.1093/nar/22.9.1536
 [YA]  - DORE J M ET AL, "Mutations dissociating the inhibitory activity of the pokeweed antiviral protein on eukaryote translation and Escherichia coli growth.", NUCLEIC ACIDS RESEARCH 11 SEP 1993, (19930911), vol. 21, no. 18, ISSN 0305-1048, pages 4200 - 4205, XP002557874 [Y] 20-25 * the whole document * [A] 1-17

DOI:   http://dx.doi.org/10.1093/nar/21.18.4200
 [Y]  - anonymous, "BL21-AI One-Shot, chemically competent E. coli", online, (20021007), Invitrogen, URL: http://tools.invitrogen.com/content/sfs/manuals/oneshot_bl21ai_man.pdf, (20091126), XP002557875 [Y] 20-25 * the whole document *
 [A]  - SAIDA F., "Unit 5.19 Overview on the expression of toxic gene products in Escherichia coli", CURRENT PROTOCOLS IN PROTEIN SCIENCE, online, (200711), vol. supplement, no. 50, doi:10.1002/0471140864.ps0519s50, pages 5.19.1 - 5.19.13, XP002557876 [A] 20-25 * the whole document *

DOI:   http://dx.doi.org/10.1002/0471140864.ps0519s50
 [T]  - anonymous, "Instructions GMBS and Sulfo-GMBS", online, PIERCE Rockford, Il, USA, URL: http://www.piercenet.com/files/1763dh4.pdf, (20091126), XP002557877 [T] 12 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.