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Extract from the Register of European Patents

EP About this file: EP2363128

EP2363128 - Indole modulators of ATP-binding cassette transporters [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.12.2016
Database last updated on 22.01.2025
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
New state(s): IS, LU, TR		published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Vertex Pharmaceuticals Incorporated
50 Northern Avenue
Boston, MA 02210 / US
[2016/07]
Former [2014/35]For all designated states
Vertex Pharmaceuticals Incorporated
50 Northern Avenue
Boston, MA 02210 / US
Former [2014/09]For all designated states
Vertex Pharmaceuticals Inc.
50 Northern Avenue
Boston, MA 02210 / US
Former [2011/36]For all designated states
Vertex Pharmaceuticals Incorporated
130 Waverly Street
Cambridge, MA 02139 / US
Inventor(s)01 / Hadida, Ruah, Sara
2356 Torrey Pines No. 16
La Jolla, CA 92037 / US
02 / Hazlewood, Anna, R.
1448 Thomas Avenue, Apt. A
San Diego, CA 92109 / US
03 / Grootenhuis, Peter, D., J.
4801 Riding Ridge Road
San Diego, CA 92130 / US
04 / Zhou, Jinglan
4466 Shorepointe Way
San Diego, CA 92130 / US
 [2015/03]
Former [2011/36]01 / Hadida, Ruah, Sara
2356 Torrey Pines No. 16
La Jolla, CA 92037 / US
02 / Halzewood, Anna, R.
1448 Thomas Avenue, Apt. A
San Diego, CA 92019 / US
03 / Grootenhuis, Peter, D., J.
4801 Riding Ridge Road
San Diego, CA 92130 / US
04 / Zhou, Jinglan
4466 Shorepointe Way
San Diego, CA 92130 / US
Representative(s)Oates, Edward Christopher, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2014/45]
Former [2014/44]Goodfellow, Hugh Robin, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Former [2011/36]Cohausz & Florack
Patent- und Rechtsanwälte Partnerschaftsgesellschaft Bleichstraße 14
40211 Düsseldorf / DE
Application number, filing date10185335.613.03.2006
[2011/36]
Priority number, dateUS20050661310P11.03.2005         Original published format: US 661310 P
US20050669174P07.04.2005         Original published format: US 669174 P
[2011/36]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2363128
Date:07.09.2011
Language:EN
[2011/36]
Type: A3 Search report 
No.:EP2363128
Date:21.09.2011
Language:EN
[2011/38]
Type: B1 Patent specification 
No.:EP2363128
Date:17.02.2016
Language:EN
[2016/07]
Search report(s)(Supplementary) European search report - dispatched on:EP24.08.2011
ClassificationIPC:A61K31/404, A61K31/4439, A61K31/454, A61K31/4725, A61K31/496, C07D403/12, C07D401/12, C07D209/18, A61P43/00
[2014/49]
CPC:
C07D209/18 (EP,US); C07D209/20 (US); A61K31/404 (EP,US);
A61K31/4439 (EP,US); A61K31/454 (EP,US); A61K31/4725 (EP,US);
A61K31/496 (EP,US); A61P1/18 (EP); A61P11/00 (EP);
A61P11/06 (EP); A61P13/02 (EP); A61P19/08 (EP);
A61P21/00 (EP); A61P21/02 (EP); A61P25/00 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/28 (EP);
A61P27/02 (EP); A61P3/00 (EP); A61P3/06 (EP);
A61P3/10 (EP); A61P31/00 (EP); A61P35/00 (EP);
A61P43/00 (EP); A61P5/00 (EP); A61P5/16 (EP);
A61P5/18 (EP); A61P7/00 (EP); A61P7/02 (EP);
A61P7/04 (EP); A61P7/10 (EP); A61P7/12 (EP);
A61P9/00 (EP); C07D401/12 (EP,US); C07D403/12 (EP,US) (-)
Former IPC [2011/36]A61K31/404, A61K31/435, A61K31/496, A61K31/44, A61K31/4453, A61P43/00, C07D209/04, C07D209/12, C07D209/18, C07D209/42, C07D401/02, C07D401/12, C07D403/02, C07D403/12
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/07]
Former [2011/36]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Indol-Modulatoren von ATP-bindenden Kassetten-Transportern[2011/36]
English:Indole modulators of ATP-binding cassette transporters[2011/36]
French:Indoles, modulateurs des transporteurs de la cassette de liaison à l ATP[2015/35]
Former [2011/36]Indoles, modulateurs des transporteurs de la cassette de liaison à l ATP
Examination procedure20.03.2012Examination requested  [2012/17]
26.04.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
04.07.2012Amendment by applicant (claims and/or description)
05.09.2012Despatch of a communication from the examining division (Time limit: M06)
15.03.2013Reply to a communication from the examining division
18.02.2015Communication of intention to grant the patent
25.06.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
03.08.2015Communication of intention to grant the patent
08.12.2015Fee for grant paid
08.12.2015Fee for publishing/printing paid
08.12.2015Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP06737945.3  / EP1865949
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060737945) is  03.03.2008
Opposition(s)18.11.2016No opposition filed within time limit [2017/04]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
04.07.2012Request for further processing filed
04.07.2012Full payment received (date of receipt of payment)
Request granted
12.07.2012Decision despatched
Fees paidRenewal fee
25.03.2011Renewal fee patent year 03
25.03.2011Renewal fee patent year 04
25.03.2011Renewal fee patent year 05
29.03.2011Renewal fee patent year 06
26.03.2012Renewal fee patent year 07
27.03.2013Renewal fee patent year 08
27.03.2014Renewal fee patent year 09
10.03.2015Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU13.03.2006
AT17.02.2016
BE17.02.2016
CY17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IS17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
MC17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SI17.02.2016
SK17.02.2016
TR17.02.2016
IE13.03.2016
LU13.03.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
[2018/32]
Former [2018/28]HU13.03.2006
AT17.02.2016
BE17.02.2016
CY17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
MC17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SI17.02.2016
SK17.02.2016
IE13.03.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
Former [2017/15]AT17.02.2016
BE17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SI17.02.2016
SK17.02.2016
IE13.03.2016
BG17.05.2016
GR18.05.2016
PT17.06.2016
Former [2017/07]AT17.02.2016
BE17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SK17.02.2016
IE13.03.2016
GR18.05.2016
PT17.06.2016
Former [2017/03]AT17.02.2016
BE17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SK17.02.2016
GR18.05.2016
PT17.06.2016
Former [2016/50]AT17.02.2016
CZ17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
RO17.02.2016
SE17.02.2016
SK17.02.2016
BE31.03.2016
GR18.05.2016
PT17.06.2016
Former [2016/49]AT17.02.2016
DK17.02.2016
EE17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
SE17.02.2016
BE31.03.2016
GR18.05.2016
PT17.06.2016
Former [2016/46]AT17.02.2016
DK17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
SE17.02.2016
BE31.03.2016
GR18.05.2016
PT17.06.2016
Former [2016/39]AT17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
LV17.02.2016
NL17.02.2016
PL17.02.2016
SE17.02.2016
BE31.03.2016
GR18.05.2016
PT17.06.2016
Former [2016/38]AT17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
NL17.02.2016
PL17.02.2016
BE31.03.2016
GR18.05.2016
PT17.06.2016
Former [2016/36]AT17.02.2016
ES17.02.2016
FI17.02.2016
IT17.02.2016
LT17.02.2016
NL17.02.2016
PL17.02.2016
BE31.03.2016
GR18.05.2016
Former [2016/35]ES17.02.2016
FI17.02.2016
GR18.05.2016
Documents cited:Search[X]US6008231  (LEBAUT GUILLAUME [FR], et al) [X] 9-11,13-16 * abstract * * column 1, line 37 - column 4, line 7 * * Schemes 1,2 * * examples 1-16,18-21,24-26; table 1 *;
 [X]US6232327  (NICKEL BERND [DE], et al) [X] 13-16,21,23,24 * abstract * * column 1, line 40 - column 4, line 19 * * scheme 2 * * tables 1a, 1b, 1e, 1f, 1g, 1h - all entries; table 1c - all entries except the example 17D table 1d - all entries except the examples 22d and 23 d * * table 1i - all entries except the example 62d-67d * * Table 2 - all entries Table 2a, 2b - all entries except the example 7D *;
 [X]US2001014690  (GUNTER ECKHARD [DE], et al) [X] 13-16,21,23,24 * abstract * * scheme 1-2 formula 1; paragraphs [0001] - [0021] *;
 [X]US2003181482  (CHEN CHIUNG-TONG [TW], et al) [X] 13-16,21,23,24 * abstract * * paragraph [0005] - paragraph [0166] * * table 1 * * examples 1-15, 19-20, 22-42, 44-102 *;
 [A]US6630482  (BECQ FREDERIC [FR], et al) [A] 1-24* abstract *;
 [X]US2004009990  (HIGGINS LINDA S [US], et al) [X] 9,10,13-16,21,23,24 * abstract * * table 2, compound 73 * * paragraph [0001] * * paragraphs [0010] , [0011] * * paragraphs [0016] - [0033] * * paragraphs [0033] - [0037] * * paragraphs [0069] - [0088] *;
 [XP]WO2005033072  (SCIOS INC [US], et al) [XP] 9-11,13-16,21,23 * abstract * * paragraph [0007] - paragraph [0011] * * paragraph [0031] - paragraph [0032] * * paragraph [0053] - paragraph [0054] *;
 [X]  - "Annual Review 2002: Respiratory Drugs", DRUGS OF THE FUTURE, PROUS SCIENCE, S.A., (20021201), vol. 27, no. 2, ISSN 0377-8282, pages 1195 - 1232, XP002397174 [X] 9,10,13-16,21,23,24 * abstract * * table - page 1195, lines 19-21, entries for AWD-12-281 * * structure of AWD-12-281 on page 1197 * * page 1197, column 1, lines 1-6 * * page 1197, column 1, lines 23-40 *
 [A]  - GOTTESMAN M M ET AL, "OVERVIEW: ABC TRANSPORTERS AND HUMAN DISEASE", JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, PLENUM PUBLISHING, NEW YORK, NY, US, (200112), vol. 33, no. 6, ISSN 0145-479X, pages 453 - 458, XP009032020 [A] 1-24 * the whole document *

DOI:   http://dx.doi.org/10.1023/A:1012866803188
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 US20100006613
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