EP2363114 - Sustained release of antiinfectives [Right-click to bookmark this link] | Status | The patent has been granted Status updated on 04.02.2018 Database last updated on 09.12.2019 | Most recent event Tooltip | 22.05.2019 | Change: Date of oral proceedings | 22.05.2019 | Deletion: Despatch of minutes of oral proceedings | Applicant(s) | For all designated states Insmed Incorporated 10 Finderne Ave, Building 10 Bridgewater NJ 08807-3365 / US | [2015/21] |
Former [2013/49] | For all designated states Insmed Incorporated Princeton Corporate Plaza 9 Deer Park Drive, Suite C Monmouth Junction, NJ 08852 / US | ||
Former [2011/36] | For all designated states Transave, Inc. Princeton Corporate Plaza 11 Deer Park Drive Suite 117 Monmouth Junction, NJ 08852 / US | Inventor(s) | 01 /
Boni, Lawrence T 40 Cummings Road Monmouth Junction, NJ 08852 / US | 02 /
Miller, Brian S. 20 Guilford Lane Mercerville, NJ 08619 / US | [2011/36] | Representative(s) | CMS Cameron McKenna Nabarro Olswang LLP Cannon Place 78 Cannon Street London EC4N 6AF / GB | [N/P] |
Former [2012/33] | Stephen, Robert John
, et al
Olswang LLP 90 High Holborn London WC1V 6XX / GB | ||
Former [2011/36] | Lee, Nicholas John Kilburn & Strode LLP 20 Red Lion Street London WC1R 4PJ / GB | Application number, filing date | 11159754.8 | 29.10.2003 | [2011/36] | Priority number, date | US20020421923P | 29.10.2002 Original published format: US 421923 P | [2011/36] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2363114 | Date: | 07.09.2011 | Language: | EN | [2011/36] | Type: | B1 Patent specification | No.: | EP2363114 | Date: | 20.05.2015 | Language: | EN | [2015/21] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 22.06.2011 | Classification | International: | A61K9/127, A61K31/7036, A61P11/00 | [2011/36] | Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR [2015/21] |
Former [2011/36] | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LI, LU, MC, NL, PT, RO, SE, SI, SK, TR | Title | German: | Verzoegerte Freisetzung von Anti-infektionsmitteln | [2011/36] | English: | Sustained release of antiinfectives | [2011/36] | French: | Libération prolongée d'anti-infectieux | [2015/01] |
Former [2011/36] | Liberation prolongée d'anti-infectieux | Examination procedure | 07.03.2012 | Examination requested [2012/16] | 16.03.2012 | Amendment by applicant (claims and/or description) | 03.05.2012 | Despatch of a communication from the examining division (Time limit: M08) | 19.02.2013 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 29.04.2013 | Reply to a communication from the examining division | 04.11.2014 | Date of oral proceedings | 26.11.2014 | Minutes of oral proceedings despatched | 02.12.2014 | Communication of intention to grant the patent | 31.03.2015 | Fee for grant paid | 31.03.2015 | Fee for publishing/printing paid | 31.03.2015 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP03816990.0 / EP1581236 | Divisional application(s) | EP14183066.1 / EP2823820 | EP18176134.7 / EP3427742 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030816990) is 24.04.2009 | Opposition(s) | Opponent(s) | 01
22.02.2016
26.02.2016
ADMISSIBLE Generics [UK] Limited Station Close Potters Bar Hertfordshire EN6 1TL / GB Opponent's representative Elkington and Fife LLP Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR / GB | [N/P] |
Former [2018/51] | |||
Opponent(s) | 01
22.02.2016
26.02.2016
ADMISSIBLE Generics [UK] Limited Station Close Potters Bar Hertfordshire EN6 1TL / GB Opponent's representative Elkington & Fife LLP Prospect House 8 Pembroke Road Sevenoaks Kent TN13 1XR / GB | ||
Former [2016/13] | |||
Opponent(s) | 01
22.02.2016
Generics [UK] Limited Station Close Potters Bar Hertfordshire EN6 1TL / GB Opponent's representative Cooke, Richard Spencer Elkington and Fife LLP Patents Department 3-4 Holborn Circus London EC1N 2HA / GB | 30.03.2016 | Invitation to proprietor to file observations on the notice of opposition | 09.08.2016 | Reply of patent proprietor to notice(s) of opposition | 15.11.2017 | Date of oral proceedings | 05.02.2018 | Despatch of minutes of oral proceedings | 05.02.2018 | Despatch of communication that the patent will be revoked | Appeal following opposition | 22.03.2018 | Appeal received No. T0778/18 | 14.06.2018 | Statement of grounds filed | 31.03.2020 | Date of oral proceedings | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 29.04.2013 | Request for further processing filed | 29.04.2013 | Full payment received (date of receipt of payment) Request granted | 14.05.2013 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 16.03.2012 | Request for further processing filed | 16.03.2012 | Full payment received (date of receipt of payment) Request granted | 03.04.2012 | Decision despatched | Fees paid | Renewal fee | 25.03.2011 | Renewal fee patent year 03 | 25.03.2011 | Renewal fee patent year 04 | 25.03.2011 | Renewal fee patent year 05 | 25.03.2011 | Renewal fee patent year 06 | 25.03.2011 | Renewal fee patent year 07 | 25.03.2011 | Renewal fee patent year 08 | 25.10.2011 | Renewal fee patent year 09 | 25.10.2012 | Renewal fee patent year 10 | 28.10.2013 | Renewal fee patent year 11 | 27.10.2014 | Renewal fee patent year 12 | Lapses during opposition Tooltip | LU | 29.10.2015 | [2016/26] | Documents cited: | Search | [Y]US5958449 (HERSCH EVAN M [US], et al) [Y] 1-9 * claims 1-9 * * column 6, paragraph 2 * * example 1 *; | [Y]WO8804573 (LIPOSOME CO INC [US]) [Y] 1-9 * claims 1,4,7,11,44-47,56 * * page 12, paragraphs 2-3 * * page 26, paragraph 2 *; | [Y]US4952405 (YAU-YOUNG ANNIE [US]) [Y] 1-9 * example 1 *; | [Y]US5820848 (BONI LAWRENCE T [US], et al) [Y] 1-9 * claims 1,13,18,19 * * column 12, lines 35-48 * * examples 10,17 *; | [Y]WO9930686 (INEX PHARMACEUTICALS CORP [CA], et al) [Y] 1-9 * claims 1,4,15,22,32 * * page 3, lines 22-25 *; | [YP]WO03075890 (TRANSAVE INC [US]) [YP] 1-9 * claims 1,3,4,7,8,46-53 * * page 8, paragraphs 3,5 * * example 1 * | Examination | WO03075889 | - WICHERT B V ET AL, "Amikacin liposomes: characterization, aerosolization, and in vitro activity against Mycobacterium avium-intracellulare in alveolar macrophages", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 78, no. 1-3, doi:10.1016/0378-5173(92)90375-C, ISSN 0378-5173, (19920101), pages 227 - 235, (19920101), XP025557898 DOI: http://dx.doi.org/10.1016/0378-5173(92)90375-C | - SCHREIER H ET AL, "Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 87, no. 1-3, doi:10.1016/0378-5173(92)90242-T, ISSN 0378-5173, (19921110), pages 183 - 193, (19921110), XP025793923 DOI: http://dx.doi.org/10.1016/0378-5173(92)90242-T | by applicant | US4522803 | US5030453 | US5169637 | US4588578 | US4975282 | US4235871 | US5008050 | US5059421 | US4515736 | US4721612 | US5041278 | - GOODMAN, GIHNAN, The Pharmaceutical Basis of Therapeutics, | - B JANOFF ET AL., PROC. NAT ACAD. SCI., (1988), vol. 85, pages 6122 - 6126 | - CULLIS ET AL., BIOTECHNOL ADV., (1987), vol. 5, no. 1, page 194 | - J. MOL. BIOL., (1965), vol. 13, no. 1, pages 238 - 52 | - PAPHADJOPOULOS ET AL., BIOCHIM. BIOPHYS. ACTA., (1967), vol. 135, pages 624 - 638 | - CHAPMAN ET AL., LIPOSOME TECHNOL., (1984), pages 1 - 18 | - BANGHAM ET AL., J. MOL. BIOL., (1965), vol. 13, pages 238 - 252 | - PAPAHADJOPOULOS ET AL., IOCHIM. BIOPHYS, ACTA., (1967), vol. 135, pages 624 - 638 | - SZOKA, JR. ET AL., ANN. REV. BIOPHYS. BIOENG., (1980), vol. 9, page 467 | - VELDHUIZEN, R., NAG, K., ORGEIG, S., POSSMAYER, F., "The Role of Lipids in Pulmonary Surfactant", BIOCHIM. BIOPHYS. ACTA, (1998), vol. 1408, pages 90 - 108 | - HAGWOOD, S., DERRICK, M., POULAIN, F., "Structure and Properties of Surfactant Protein B", BIOCHIN. BIOPHYS. ACTA, (1998), vol. 1408, pages 150 - 160 | - JOHANSSON, J., "Structure and Properties of Surfactant ProteinC", BIOCHIM. BIOPHYS. ACTA, (1998), vol. 1408, pages 161 - 172 | - IKEGAMI, M., JOBE, A.H., "Surfactant Protein Metabolism in vivo", BIOCHIM. BIOPHYS. ACTA, (1998), vol. 1408, pages 218 - 225 | - COUVEUR, P., FATTEL, E., ANDREMONT,A., "Liposomes and Nanoparticles in the Treatment of Intracellular Bacterial Infections", PHARM RES, (1991), vol. 8, pages 1079 - 1085 | - GONZALES-ROTHI, R.J., CASACE, J., STRAUB, L., SCHREIER, H., "Liposomes and Pulmonary Alveolar Macrophages: Functional and Morphologic Interactions", EXP. LUNG RES., (1991), vol. 17, pages 685 - 705 | - SWENSON, C.E., PILKIEWICZ, F.G., CYNAMON, M.H., "Liposomal Aminoglycosides and TLC-65", AIDS PATIENT CARE, (199112), pages 290 - 296 | - COSTERTON, J.W., STEWART, P.S., GREENBERG, E.P., "Bacterial Biofilms: A Common Cause of Persistent Infections", SCIENCE, (1999), vol. 284, pages 1318 - 1322 | - CASH, H.A., WOODS, D.E., MCCULLOUGH, W.G., JOHANSON, J.R., BASS, J.A., "A Rat Model of Chronic Respiratory Infection with Pseudomonas aeruginosa", AMERICAN REVIEW OF RESPIRATORY DISEASE, (1979), vol. 119, pages 453 - 459 | - CANTIN, A.M., WOODS, D.E., "Aemsolized Prolastin Suppresses Bacterial Proliferation in a Model of Chronic Pseudomonas aeruginosa Lung Infection", AM. J. RESPIR. CRIT. CARE MED., (1999), vol. 160, pages 1130 - 1135 | - RAMSEY, B.W., DORKIN, H.L., EISENBERG, J.D., GIBSON, R.L., HARWOOD, I.R., KRAVITZ, P.M., "Efficacy of Aerosolized Tobramycin in Patients with cystic Fibrosis", NEW ENGLAND J. OF MED., (1993), vol. 328, pages 1740 - 1746 | - MENDEIMAN, P.M., SMITH, A.L., LEVY, J., WEBER, A., RAMSEY, B., DAVIS, R.L., "Aminoglycoside Penetration, Inactivation, and Efficacy in Cystic Fibrosis Sputum", AMERICAN REVIEW OF RESPIRATORY DISEASE, (1985), vol. 132, pages 761 - 765 | - PRICE, K.E., DEFURIA, M.D., PURSIANO, T.A., "Amikacin, an aminoglycoside with marked activity against antibiotic-resistant clinical isolates", J INFECT DIS, (1976), vol. 134, pages 249 - 261 | - DAMASO, D., MORENO-LOPEZ, M., MARTINEZ-BELTRAN, J., GARCIA-IGLESIAS, M.C., "Susceptibility of current clinical isolates of Pseudomonas aeruginosa and enteric gram-negative bacilli to Amikacin and other aminoglycoside antibiotics", J INFECT DIS, (1976), vol. 134, pages 394 - 90 | - PILE, J.C., MALONE, J.D., EITZEN, E.M., FRIEDLANDER, A.M., "Anthrax as a potential biological warfare agent", ARCH. INTERN. 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PATH., (1968), vol. 44, pages 416 - 426 | US20030634144 | US20030383173 | US20030383004 | WO2003US06847 | Opposition | US5958449 | WO8804573 | US4592405 | WO9930686 | WO03075890 | WO03075889 | US5820848 | - WICHERT B V et al., "Amikacin liposomes: characterization, aerosolization, and in vitro activity against Mycobacterium avium-intracellulare in alveolar macrophages", International Journal of Pharmaceutics, (19920100), vol. 78, no. 1-3, pages 227 - 235, XP025557898 DOI: http://dx.doi.org/10.1016/0378-5173(92)90375-C | - SCHREIER H et al., "Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep", International Journal of Pharmaceutics, (19921010), vol. 87, no. 1-3, pages 183 - 193, XP025793923 DOI: http://dx.doi.org/10.1016/0378-5173(92)90242-T | - BLASER et al., "Once Daily Dosing of Aminoglycosides", Eur. CLin. Microbiol. Infect. Dis, (19951200), vol. 14, no. 12, pages 1029 - 1038, XP055261104 |