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Extract from the Register of European Patents

EP About this file: EP2575596

EP2575596 - METHODS OF DETERMINING AMYLOID BETA TURNOVER IN BLOOD [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  24.02.2017
Database last updated on 26.03.2025
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
The Washington University
One Brookings Drive
St. Louis, MO 63130 / US
[2013/15]
Inventor(s)01 / BATEMAN, Randall J.
One Brookings Drive
St. Louis, Missouri 63130 / US
02 / HOLTZMAN, David M.
One Brookings Drive
St. Louis, Missouri 63130 / US
03 / MAWUENYEGA, Kwasi G.
One Brookings Drive
St. Louis, Missouri 63130 / US
 [2013/15]
Representative(s)Turner, Rhiannon Rosalind, et al
Greaves Brewster LLP
Copa House
Station Road
Cheddar, BS27 3AH / GB
[2013/15]
Application number, filing date11787251.524.05.2011
[2016/16]
WO2011US37754
Priority number, dateUS20100347554P24.05.2010         Original published format: US 347554 P
[2013/15]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2011149947
Date:01.12.2011
Language:EN
[2011/48]
Type: A2 Application without search report 
No.:EP2575596
Date:10.04.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 01.12.2011 takes the place of the publication of the European patent application.
[2013/15]
Type: B1 Patent specification 
No.:EP2575596
Date:20.04.2016
Language:EN
[2016/16]
Search report(s)International search report - published on:US26.01.2012
(Supplementary) European search report - dispatched on:EP04.11.2013
ClassificationIPC:G01N33/68
[2015/46]
CPC:
G01N33/6896 (EP,US); G01N33/68 (KR); A61K51/00 (KR);
G01N33/48 (KR); G01N33/58 (KR); G01N2333/4709 (EP,US)
Former IPC [2013/49]A61B5/00, G01N33/48, G01N33/68
Former IPC [2013/15]A61B5/00, G01N33/48
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/15]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR BESTIMMUNG DES AMYLOID-BETA-UMSATZES IM BLUT[2013/15]
English:METHODS OF DETERMINING AMYLOID BETA TURNOVER IN BLOOD[2013/15]
French:MÉTHODES POUR DÉTERMINER UN RENOUVELLEMENT DE BÊTA-AMYLOÏDES DANS LE SANG[2013/15]
Entry into regional phase21.12.2012National basic fee paid 
21.12.2012Search fee paid 
21.12.2012Designation fee(s) paid 
21.12.2012Examination fee paid 
Examination procedure21.12.2012Examination requested  [2013/15]
15.07.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
11.09.2014Amendment by applicant (claims and/or description)
06.02.2015Despatch of a communication from the examining division (Time limit: M04)
11.06.2015Reply to a communication from the examining division
23.06.2015Despatch of a communication from the examining division (Time limit: M02)
30.07.2015Reply to a communication from the examining division
02.11.2015Communication of intention to grant the patent
03.03.2016Fee for grant paid
03.03.2016Fee for publishing/printing paid
03.03.2016Receipt of the translation of the claim(s)
Divisional application(s)EP16158001.4  / EP3066979
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.02.2015
Opposition(s)23.01.2017No opposition filed within time limit [2017/13]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
11.09.2014Request for further processing filed
11.09.2014Full payment received (date of receipt of payment)
Request granted
22.09.2014Decision despatched
Fees paidRenewal fee
10.05.2013Renewal fee patent year 03
27.03.2014Renewal fee patent year 04
12.05.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU24.05.2011
AL20.04.2016
BE20.04.2016
BG20.04.2016
CY20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
IS20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
MK20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
TR20.04.2016
LU24.05.2016
MT31.05.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
[2018/46]
Former [2018/38]HU24.05.2011
BE20.04.2016
BG20.04.2016
CY20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
IS20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
MK20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
TR20.04.2016
LU24.05.2016
MT31.05.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2018/31]HU24.05.2011
BE20.04.2016
CY20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
IS20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
MK20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
TR20.04.2016
LU24.05.2016
MT31.05.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2018/29]HU24.05.2011
BE20.04.2016
CY20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
MK20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
TR20.04.2016
LU24.05.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2018/28]HU24.05.2011
BE20.04.2016
CY20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
MK20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2017/37]BE20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SI20.04.2016
SK20.04.2016
SM20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2017/11]BE20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SK20.04.2016
SM20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2017/10]BE20.04.2016
EE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
NL20.04.2016
PL20.04.2016
RO20.04.2016
RS20.04.2016
SK20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2017/07]BE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
MC20.04.2016
NL20.04.2016
PL20.04.2016
RS20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2017/03]BE20.04.2016
FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
NL20.04.2016
PL20.04.2016
RS20.04.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2016/51]FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
NL20.04.2016
PL20.04.2016
RS20.04.2016
BE31.05.2016
NO20.07.2016
GR21.07.2016
PT22.08.2016
Former [2016/50]FI20.04.2016
HR20.04.2016
LT20.04.2016
LV20.04.2016
NL20.04.2016
PL20.04.2016
RS20.04.2016
BE31.05.2016
NO20.07.2016
Former [2016/49]FI20.04.2016
LT20.04.2016
NL20.04.2016
PL20.04.2016
BE31.05.2016
NO20.07.2016
Former [2016/46]LT20.04.2016
BE31.05.2016
NO20.07.2016
Former [2016/37]BE31.05.2016
Documents cited:Search[XI]WO03068919  (UNIV CALIFORNIA [US]) [X] 1,2,4,8,11,13 * pages 1,20,26; claims 20,27,54 *[I] 12,14,15;
 [X]WO2006017812  (KINEMED INC [US], et al) [X] 1-10 * claims 1,6 *;
 [X]  - RANDALL J BATEMAN ET AL, "Human amyloid-[beta] synthesis and clearance rates as measured in cerebrospinal fluid in vivo", NATURE MEDICINE, (20060625), vol. 12, no. 7, doi:10.1038/nm1438, ISSN 1078-8956, pages 856 - 861, XP055085288 [X] 1-10 * page 857; figure 2 *

DOI:   http://dx.doi.org/10.1038/nm1438
International search[X]US2008145941  (BATEMAN RANDALL JOHN [US], et al);
 [A]US2009041661  (HELLERSTEIN MARC K [US]);
 [XP]US2011111511  (BATEMAN RANDALL JOHN [US], et al)
 [XP]  - MAWUENYEGA ET AL., "Decreased Clearance of CNS Beta-Amyloid in Alzheimer's Disease", SCIENCE, (20101209), vol. 330, page 1774
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.