EP2652496 - VACCINE ANTIGENS THAT DIRECT IMMUNITY TO CONSERVED EPITOPES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 23.11.2018 Database last updated on 11.11.2024 | |
Former | The patent has been granted Status updated on 15.12.2017 | ||
Former | Grant of patent is intended Status updated on 04.07.2017 | Most recent event Tooltip | 26.06.2020 | Lapse of the patent in a contracting state New state(s): MK | published on 29.07.2020 [2020/31] | Applicant(s) | For all designated states The University of Utah Research Foundation 615 Arapeen Drive, Suite 310 Salt Lake City, Utah 84108 / US | [2013/43] | Inventor(s) | 01 /
BOCK, Susan, C. c/o University of Utah 50 North Medical Drive Salt Lake City Utah 84132 / US | [2013/43] | Representative(s) | Harrison IP Limited 3 Ebor House Millfield Lane Nether Poppleton York YO26 6QY / GB | [N/P] |
Former [2018/03] | Harrison IP Limited 3 Ebor House Millfield Lane Nether Poppleton, York YO26 6QY / GB | ||
Former [2013/43] | D'Arcy, Julia Harrison IP 1st Floor Box Tree House Northminster Business Park, Northfield Lane York, YO26 6QU / GB | Application number, filing date | 11849352.7 | 12.12.2011 | [2018/03] | WO2011US64442 | Priority number, date | US20100457028P | 13.12.2010 Original published format: US 457028 P | US201161626792P | 03.10.2011 Original published format: US 201161626792 P | [2013/43] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2012082634 | Date: | 21.06.2012 | Language: | EN | [2012/25] | Type: | A1 Application with search report | No.: | EP2652496 | Date: | 23.10.2013 | Language: | EN | The application published by WIPO in one of the EPO official languages on 21.06.2012 takes the place of the publication of the European patent application. | [2013/43] | Type: | B1 Patent specification | No.: | EP2652496 | Date: | 17.01.2018 | Language: | EN | [2018/03] | Search report(s) | International search report - published on: | US | 21.06.2012 | (Supplementary) European search report - dispatched on: | EP | 28.04.2014 | Classification | IPC: | G01N33/48, A61K39/00 | [2013/43] | CPC: |
A61K39/12 (EP,US);
C07K14/005 (US);
A61K39/145 (US);
A61P31/16 (EP);
A61P37/04 (EP);
A61K2039/555 (EP,US);
A61K2039/55561 (EP,US);
A61K2039/55566 (EP,US);
A61K2039/55572 (EP,US);
A61K2039/55577 (EP,US);
A61K2039/55583 (EP,US);
A61K2039/58 (EP,US);
A61K2300/00 (EP,US);
A61K35/76 (EP,US);
A61K9/0019 (EP,US);
C12N2760/16034 (EP,US);
C12N2760/16111 (EP,US);
C12N2760/16121 (EP,US);
C12N2760/16122 (US);
C12N2760/16134 (EP,US);
C12N2760/16151 (EP,US);
C12N2760/16171 (EP,US)
(-)
| C-Set: |
A61K2039/55561, A61K2039/55566, A61K2039/55583, A61K2039/555, A61K2039/55572, A61K35/76, A61K9/0019, A61K2039/55577, A61K2300/00 (US);
C12N2760/16121, C12N2760/16111, C12N2760/16134, C12N2760/16151, C12N2760/16171 (US) | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/43] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | IMPFSTOFF-ANTIGENE ZUR AUSSTATTUNG KONSERVIERTER EPITOPE MIT IMMUNITÄT | [2013/43] | English: | VACCINE ANTIGENS THAT DIRECT IMMUNITY TO CONSERVED EPITOPES | [2013/43] | French: | ANTIGÈNES DE VACCIN QUI CONTRÔLENT L'IMMUNITÉ CONTRE DES ÉPITOPES CONSERVÉS | [2013/43] | Entry into regional phase | 25.06.2013 | National basic fee paid | 25.06.2013 | Search fee paid | 25.06.2013 | Designation fee(s) paid | 25.06.2013 | Examination fee paid | Examination procedure | 25.06.2013 | Examination requested [2013/43] | 09.01.2015 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time | 13.03.2015 | Amendment by applicant (claims and/or description) | 08.05.2015 | Despatch of a communication from the examining division (Time limit: M06) | 16.11.2015 | Reply to a communication from the examining division | 21.01.2016 | Despatch of a communication from the examining division (Time limit: M04) | 23.05.2016 | Reply to a communication from the examining division | 03.07.2017 | Communication of intention to grant the patent | 01.11.2017 | Fee for grant paid | 01.11.2017 | Fee for publishing/printing paid | 01.11.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 08.05.2015 | Opposition(s) | 18.10.2018 | No opposition filed within time limit [2018/52] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 13.03.2015 | Request for further processing filed | 13.03.2015 | Full payment received (date of receipt of payment) Request granted | 25.03.2015 | Decision despatched | Fees paid | Renewal fee | 31.12.2013 | Renewal fee patent year 03 | 05.12.2014 | Renewal fee patent year 04 | 07.12.2015 | Renewal fee patent year 05 | 08.12.2016 | Renewal fee patent year 06 | 08.12.2017 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 12.12.2011 | AL | 17.01.2018 | AT | 17.01.2018 | CY | 17.01.2018 | CZ | 17.01.2018 | DK | 17.01.2018 | EE | 17.01.2018 | ES | 17.01.2018 | FI | 17.01.2018 | HR | 17.01.2018 | IT | 17.01.2018 | LT | 17.01.2018 | LV | 17.01.2018 | MC | 17.01.2018 | MK | 17.01.2018 | NL | 17.01.2018 | PL | 17.01.2018 | PT | 17.01.2018 | RO | 17.01.2018 | RS | 17.01.2018 | SI | 17.01.2018 | SK | 17.01.2018 | SM | 17.01.2018 | TR | 17.01.2018 | BG | 17.04.2018 | NO | 17.04.2018 | GR | 18.04.2018 | IS | 17.05.2018 | [2020/31] |
Former [2020/30] | HU | 12.12.2011 | |
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NO | 17.04.2018 | Documents cited: | Search | [A] - PERNILLE HASTE ANDERSEN ET AL, "Prediction of residues in discontinuous B-cell epitopes using protein 3D structures", PROTEIN SCIENCE, (20061101), vol. 15, no. 11, doi:10.1110/ps.062405906, ISSN 0961-8368, pages 2558 - 2567, XP055113267 [A] 1-4 DOI: http://dx.doi.org/10.1110/ps.062405906 | [A] - JULIA V PONOMARENKO ET AL, "B-CELL EPITOPE PREDICTION", STRUCTURAL INFORMATICS, (20090101), XP055113769 [A] 1-4 | [A] - EL-MANZALAWY YASSER ET AL, "Recent advances in B-cell epitope prediction methods", IMMUNOME RESEARCH, BIOMED CENTRAL, LONDON, GB, (20101103), vol. 6, no. Suppl 2, doi:10.1186/1745-7580-6-S2-S2, ISSN 1745-7580, page S2, XP021080944 [A] 1-4 DOI: http://dx.doi.org/10.1186/1745-7580-6-S2-S2 | [X] - NAGATA S ET AL, "Removal of B cell epitopes as a practical approach for reducing the immunogenicity of foreign protein-based therapeutics", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 61, no. 11, doi:10.1016/J.ADDR.2009.07.014, ISSN 0169-409X, (20090930), pages 977 - 985, (20090811), XP026666157 [X] 1,2 * abstract, p.980 col.1 par.2 * DOI: http://dx.doi.org/10.1016/j.addr.2009.07.014 | International search | [Y]US2008032921 (ALEXANDER JEFFERY L [US], et al); | [X]US2009162383 (PADLAN EDUARDO A [US]); | [Y]US2010061990 (SASISEKHARAN RAM [US], et al) | by applicant | - GERHARD, W ET AL., "Prospects for Universal Influenza Virus Vaccine", EMERGING INFECTIOUS DISEASES, (2006), vol. 12, doi:doi:10.3201/eid1204.051020, page 569, XP002711940 DOI: http://dx.doi.org/10.3201/eid1204.051020 | - SUBBARAO, K ET AL., "Development of effective vaccines against pandemic influenza", IMMUNITY, (2006), vol. 24, no. 1, pages 5 - 9 | - KAISER, J., "A One-Size-Fits-All Flu Vaccine", SCIENCE, (2006), vol. 312, page 380 | - CORTI, D. ET AL., "Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine", J CLIN INVEST, (2010), vol. 120, no. 5, pages 1663 - 1673 | - SULLIVAN, J.S. ET AL., "Heterosubtypic antiavian H5N1 influenza antibodies in intravenous immunoglobulins from globally separate populations protect against H5N1 infection in cell culture", J MOL GENET MED, (2009), vol. 3, no. 2, pages 217 - 24 | - SUI, J. ET AL., "Wide prevalence of heterosubtypic broadly neutralizing human antiinfluenza A antibodies", CLIN INFECT DIS, (2011), vol. 52, no. 8, doi:doi:10.1093/cid/cir121, pages 1003 - 1009, XP055044420 DOI: http://dx.doi.org/10.1093/cid/cir121 | - WRAMMERT, J. 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WEI ET AL., "Induction of broadly neutralizing HINI influenza antibodies by vaccination", SCIENCE, (20100715), vol. 329, pages 2060 - 2064 | - BOMMAKANTI ET AL., "Design of an HA2based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge", PROC NATL ACAD SCI U S A, (2010), vol. 107, no. 31, doi:doi:10.1073/PNAS.1007465107, pages 13701 - 6, XP002675041 DOI: http://dx.doi.org/10.1073/PNAS.1007465107 | - WANG ET AL., "Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.", PROC NATL ACAD SCI USA, (2010), vol. 107, no. 44, doi:doi:10.1073/PNAS.1013387107, pages 18979 - 84, XP002675044 DOI: http://dx.doi.org/10.1073/PNAS.1013387107 | - KHURANA, "Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets", PLOS MED, (2009), vol. 6, no. 4, doi:doi:10.1371/journal.pmed.1000049, page E1000049, XP055015999 DOI: http://dx.doi.org/10.1371/journal.pmed.1000049 | - WHITTLE ET AL., "Broadly neutralizing human antibody that recognizes the receptorbinding pocket of influenza virus hemagglutinin", PROC NATL ACAD SCI U S A, (2011), vol. 108, no. 34, doi:doi:10.1073/pnas.1111497108, page 1421621, XP002693351 DOI: http://dx.doi.org/10.1073/pnas.1111497108 | - YOSHIDA ET AL., "Crossprotective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses", PLOS PATHOG, (2009), vol. 5, no. 3, doi:doi:10.1371/journal.ppat.1000350, page E1000350, XP002541080 DOI: http://dx.doi.org/10.1371/journal.ppat.1000350 | - BIANCHI, E. 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