EP2707354 - QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 04.03.2016 Database last updated on 11.11.2024 | Most recent event Tooltip | 12.10.2018 | Lapse of the patent in a contracting state New state(s): AL | published on 14.11.2018 [2018/46] | Applicant(s) | For all designated states Nicox Science Ireland Riverside One Sir John Rogerson's Quay Dublin 2 / IE | [2014/48] |
Former [2014/12] | For all designated states Nicox S.A. Taissounières HB4 1681 route des Dolines BP 313 06560 Sophia Antipolis - Valbonne / FR | Inventor(s) | 01 /
RONSIN, Gael Via Francesco Albani 58 I-20148 Milano / IT | 02 /
STORONI, Laura Via Dante 57 I-20031 Cesano Maderno (MI) / IT | 03 /
BENEDINI, Francesca Via Spilamberto 16 I-20097 San Donato Milanese (MI) / IT | [2014/12] | Representative(s) | Barchielli, Giovanna Bianchetti & Minoja with Trevisan & Cuonzo IPS Srl Via Plinio, 63 20129 Milano / IT | [N/P] |
Former [2014/12] | Barchielli, Giovanna Bianchetti Bracco Minoja S.r.l. Via Plinio, 63 20129 Milano / IT | Application number, filing date | 12788142.3 | 23.10.2012 | WO2012EP70953 | Priority number, date | EP20110186301 | 24.10.2011 Original published format: EP 11186301 | [2014/12] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013060673 | Date: | 02.05.2013 | Language: | EN | [2013/18] | Type: | A1 Application with search report | No.: | EP2707354 | Date: | 19.03.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 02.05.2013 takes the place of the publication of the European patent application. | [2014/12] | Type: | B1 Patent specification | No.: | EP2707354 | Date: | 29.04.2015 | Language: | EN | [2015/18] | Search report(s) | International search report - published on: | EP | 02.05.2013 | Classification | IPC: | C07C203/04, C07C203/08, A61K31/21, A61P9/08 | [2014/12] | CPC: |
C07C203/04 (EP,US);
A61K31/122 (EP,US);
A61K31/7024 (EP,US);
A61K45/06 (EP,US);
A61P21/00 (EP);
A61P25/00 (EP);
A61P27/02 (EP);
A61P27/06 (EP);
A61P9/00 (EP);
A61P9/08 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
A61P9/14 (EP);
C07C323/22 (EP,US);
C07C323/53 (US);
C07D307/20 (EP,US);
C07H11/02 (EP,US);
C07C2601/16 (EP,US);
C07C2602/10 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/12] | Extension states | BA | 13.12.2013 | ME | 13.12.2013 | Title | German: | CHINONBASIERTE STICKOXID-ABGEBENDE VERBINDUNGEN | [2014/12] | English: | QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS | [2014/12] | French: | COMPOSÉS DONNEURS D'OXYDE NITRIQUE À BASE DE QUINONE | [2014/12] | Entry into regional phase | 13.12.2013 | National basic fee paid | 13.12.2013 | Designation fee(s) paid | 13.12.2013 | Examination fee paid | Examination procedure | 10.04.2013 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 13.12.2013 | Examination requested [2014/12] | 12.12.2014 | Communication of intention to grant the patent | 19.03.2015 | Fee for grant paid | 19.03.2015 | Fee for publishing/printing paid | 19.03.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | EP13198180.5 / EP2722326 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 12.12.2014 | Opposition(s) | 01.02.2016 | No opposition filed within time limit [2016/14] | Fees paid | Renewal fee | 27.10.2014 | Renewal fee patent year 03 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 23.10.2012 | AL | 29.04.2015 | AT | 29.04.2015 | BE | 29.04.2015 | BG | 29.04.2015 | CY | 29.04.2015 | CZ | 29.04.2015 | DK | 29.04.2015 | EE | 29.04.2015 | FI | 29.04.2015 | HR | 29.04.2015 | LT | 29.04.2015 | LV | 29.04.2015 | MC | 29.04.2015 | MK | 29.04.2015 | MT | 29.04.2015 | NL | 29.04.2015 | PL | 29.04.2015 | RO | 29.04.2015 | RS | 29.04.2015 | SE | 29.04.2015 | SI | 29.04.2015 | SK | 29.04.2015 | SM | 29.04.2015 | TR | 29.04.2015 | NO | 29.07.2015 | GR | 30.07.2015 | IS | 29.08.2015 | PT | 31.08.2015 | IE | 23.10.2015 | LU | 23.10.2015 | CH | 31.10.2015 | LI | 31.10.2015 | [2018/46] |
Former [2018/45] | HU | 23.10.2012 | |
AT | 29.04.2015 | ||
BE | 29.04.2015 | ||
BG | 29.04.2015 | ||
CY | 29.04.2015 | ||
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
MK | 29.04.2015 | ||
MT | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SE | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
SM | 29.04.2015 | ||
TR | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
IE | 23.10.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2018/31] | HU | 23.10.2012 | |
AT | 29.04.2015 | ||
BE | 29.04.2015 | ||
BG | 29.04.2015 | ||
CY | 29.04.2015 | ||
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
MK | 29.04.2015 | ||
MT | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SE | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
SM | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
IE | 23.10.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2017/39] | HU | 23.10.2012 | |
AT | 29.04.2015 | ||
BE | 29.04.2015 | ||
BG | 29.04.2015 | ||
CY | 29.04.2015 | ||
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
MT | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SE | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
SM | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
IE | 23.10.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2016/45] | AT | 29.04.2015 | |
BE | 29.04.2015 | ||
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
IE | 23.10.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2016/37] | AT | 29.04.2015 | |
BE | 29.04.2015 | ||
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2016/34] | AT | 29.04.2015 | |
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
LU | 23.10.2015 | ||
CH | 31.10.2015 | ||
LI | 31.10.2015 | ||
Former [2016/28] | AT | 29.04.2015 | |
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
MC | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
LU | 23.10.2015 | ||
Former [2016/26] | AT | 29.04.2015 | |
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
LU | 23.10.2015 | ||
Former [2016/24] | AT | 29.04.2015 | |
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SI | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2016/10] | AT | 29.04.2015 | |
CZ | 29.04.2015 | ||
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
PL | 29.04.2015 | ||
RO | 29.04.2015 | ||
RS | 29.04.2015 | ||
SK | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2016/09] | AT | 29.04.2015 | |
DK | 29.04.2015 | ||
EE | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
RS | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2016/07] | AT | 29.04.2015 | |
DK | 29.04.2015 | ||
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
RS | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2015/51] | AT | 29.04.2015 | |
FI | 29.04.2015 | ||
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
RS | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2015/50] | FI | 29.04.2015 | |
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
RS | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
IS | 29.08.2015 | ||
PT | 31.08.2015 | ||
Former [2015/49] | FI | 29.04.2015 | |
HR | 29.04.2015 | ||
LT | 29.04.2015 | ||
LV | 29.04.2015 | ||
NL | 29.04.2015 | ||
RS | 29.04.2015 | ||
NO | 29.07.2015 | ||
GR | 30.07.2015 | ||
PT | 31.08.2015 | ||
Former [2015/42] | NL | 29.04.2015 | Cited in | International search | [IY]GB2349385 (TEIJIN LTD [JP]) [I] 1,2,4,8-12,15,17,19-32 * the whole document * * compound 5 * [Y] 3,5-7,13,14,16,18; | [Y] - MURAKAMI M ET AL, "Superoxide radical scavenging activity of idebenone in vitro studied by ESR spin trapping method and direct ESR measurement at liquid nitrogen temperature", ARCHIVES OF GERONTOLOGY AND GERIATRICS, ELSEVIER, AMSTERDAM, NL, vol. 11, no. 3, doi:10.1016/0167-4943(90)90065-E, ISSN 0167-4943, (19901101), pages 199 - 214, (19901101), XP023472818 [Y] 3,5-7,13,14,16,18 * Summary;; table I * DOI: http://dx.doi.org/10.1016/0167-4943(90)90065-E | [A] - DE ABREU F C DE O ET AL, "Nitrooxyquinones: synthesis, X-ray diffraction and electrochemical studies", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, (20021104), vol. 43, no. 45, doi:10.1016/S0040-4039(02)01957-3, ISSN 0040-4039, pages 8153 - 8157, XP004387211 [A] 1-32 * compound 1 * DOI: http://dx.doi.org/10.1016/S0040-4039(02)01957-3 | by applicant | EP0362575 | EP0451760 | WO9204337 | US5591758 | EP1120419 | - MUNZEL T; MOLLNAU H; HARTMANN M ET AL., "Effects of a nitrate-free interval on tolerance, vasoconstrictor sensitivity and vascular superoxide production", J AM COLL CARDIOL., (2000), vol. 36, pages 628 - 634 | - DUVEAU D.Y., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441 | - BREYER, S., CHEM MED CHEM, (2009), vol. 4, no. 5, pages 761 - 768 | - DUVEAU D,Y ET AL., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441 | - KAYASHIMA, TOMOKO ET AL., BIOOR & MED CHEMISTRY, (2010), vol. 18, no. 10, pages 6305 - 6309 | - DUVEAU D. Y., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441 | - CHEM MED CHEM, (2009), vol. 4, no. 5, pages 761 - 768 | - BOSCHI D. ET AL., J. MED. CHEM., (2006), vol. 49, pages 2886 - 2897 | - BIOORGANIC & MEDICINAL CHEMISTRY, (2010), vol. 18, pages 6429 - 6441 |