blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2707354

EP2707354 - QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.03.2016
Database last updated on 11.11.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL
published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Nicox Science Ireland
Riverside One
Sir John Rogerson's Quay
Dublin 2 / IE
[2014/48]
Former [2014/12]For all designated states
Nicox S.A.
Taissounières HB4 1681 route des Dolines BP 313
06560 Sophia Antipolis - Valbonne / FR
Inventor(s)01 / RONSIN, Gael
Via Francesco Albani 58
I-20148 Milano / IT
02 / STORONI, Laura
Via Dante 57
I-20031 Cesano Maderno (MI) / IT
03 / BENEDINI, Francesca
Via Spilamberto 16
I-20097 San Donato Milanese (MI) / IT
 [2014/12]
Representative(s)Barchielli, Giovanna
Bianchetti & Minoja with
Trevisan & Cuonzo IPS Srl
Via Plinio, 63
20129 Milano / IT
[N/P]
Former [2014/12]Barchielli, Giovanna
Bianchetti Bracco Minoja S.r.l.
Via Plinio, 63
20129 Milano / IT
Application number, filing date12788142.323.10.2012
WO2012EP70953
Priority number, dateEP2011018630124.10.2011         Original published format: EP 11186301
[2014/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013060673
Date:02.05.2013
Language:EN
[2013/18]
Type: A1 Application with search report 
No.:EP2707354
Date:19.03.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 02.05.2013 takes the place of the publication of the European patent application.
[2014/12]
Type: B1 Patent specification 
No.:EP2707354
Date:29.04.2015
Language:EN
[2015/18]
Search report(s)International search report - published on:EP02.05.2013
ClassificationIPC:C07C203/04, C07C203/08, A61K31/21, A61P9/08
[2014/12]
CPC:
C07C203/04 (EP,US); A61K31/122 (EP,US); A61K31/7024 (EP,US);
A61K45/06 (EP,US); A61P21/00 (EP); A61P25/00 (EP);
A61P27/02 (EP); A61P27/06 (EP); A61P9/00 (EP);
A61P9/08 (EP); A61P9/10 (EP); A61P9/12 (EP);
A61P9/14 (EP); C07C323/22 (EP,US); C07C323/53 (US);
C07D307/20 (EP,US); C07H11/02 (EP,US); C07C2601/16 (EP,US);
C07C2602/10 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/12]
Extension statesBA13.12.2013
ME13.12.2013
TitleGerman:CHINONBASIERTE STICKOXID-ABGEBENDE VERBINDUNGEN[2014/12]
English:QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS[2014/12]
French:COMPOSÉS DONNEURS D'OXYDE NITRIQUE À BASE DE QUINONE[2014/12]
Entry into regional phase13.12.2013National basic fee paid 
13.12.2013Designation fee(s) paid 
13.12.2013Examination fee paid 
Examination procedure10.04.2013Request for preliminary examination filed
International Preliminary Examining Authority: EP
13.12.2013Examination requested  [2014/12]
12.12.2014Communication of intention to grant the patent
19.03.2015Fee for grant paid
19.03.2015Fee for publishing/printing paid
19.03.2015Receipt of the translation of the claim(s)
Divisional application(s)EP13198180.5  / EP2722326
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.12.2014
Opposition(s)01.02.2016No opposition filed within time limit [2016/14]
Fees paidRenewal fee
27.10.2014Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.10.2012
AL29.04.2015
AT29.04.2015
BE29.04.2015
BG29.04.2015
CY29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
MK29.04.2015
MT29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SE29.04.2015
SI29.04.2015
SK29.04.2015
SM29.04.2015
TR29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
IE23.10.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
[2018/46]
Former [2018/45]HU23.10.2012
AT29.04.2015
BE29.04.2015
BG29.04.2015
CY29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
MK29.04.2015
MT29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SE29.04.2015
SI29.04.2015
SK29.04.2015
SM29.04.2015
TR29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
IE23.10.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2018/31]HU23.10.2012
AT29.04.2015
BE29.04.2015
BG29.04.2015
CY29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
MK29.04.2015
MT29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SE29.04.2015
SI29.04.2015
SK29.04.2015
SM29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
IE23.10.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2017/39]HU23.10.2012
AT29.04.2015
BE29.04.2015
BG29.04.2015
CY29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
MT29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SE29.04.2015
SI29.04.2015
SK29.04.2015
SM29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
IE23.10.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2016/45]AT29.04.2015
BE29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
IE23.10.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2016/37]AT29.04.2015
BE29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2016/34]AT29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
LU23.10.2015
CH31.10.2015
LI31.10.2015
Former [2016/28]AT29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
MC29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
LU23.10.2015
Former [2016/26]AT29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
LU23.10.2015
Former [2016/24]AT29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SI29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2016/10]AT29.04.2015
CZ29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
PL29.04.2015
RO29.04.2015
RS29.04.2015
SK29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2016/09]AT29.04.2015
DK29.04.2015
EE29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
RS29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2016/07]AT29.04.2015
DK29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
RS29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2015/51]AT29.04.2015
FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
RS29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2015/50]FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
RS29.04.2015
NO29.07.2015
GR30.07.2015
IS29.08.2015
PT31.08.2015
Former [2015/49]FI29.04.2015
HR29.04.2015
LT29.04.2015
LV29.04.2015
NL29.04.2015
RS29.04.2015
NO29.07.2015
GR30.07.2015
PT31.08.2015
Former [2015/42]NL29.04.2015
Cited inInternational search[IY]GB2349385  (TEIJIN LTD [JP]) [I] 1,2,4,8-12,15,17,19-32 * the whole document * * compound 5 * [Y] 3,5-7,13,14,16,18;
 [Y]  - MURAKAMI M ET AL, "Superoxide radical scavenging activity of idebenone in vitro studied by ESR spin trapping method and direct ESR measurement at liquid nitrogen temperature", ARCHIVES OF GERONTOLOGY AND GERIATRICS, ELSEVIER, AMSTERDAM, NL, vol. 11, no. 3, doi:10.1016/0167-4943(90)90065-E, ISSN 0167-4943, (19901101), pages 199 - 214, (19901101), XP023472818 [Y] 3,5-7,13,14,16,18 * Summary;; table I *

DOI:   http://dx.doi.org/10.1016/0167-4943(90)90065-E
 [A]  - DE ABREU F C DE O ET AL, "Nitrooxyquinones: synthesis, X-ray diffraction and electrochemical studies", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, (20021104), vol. 43, no. 45, doi:10.1016/S0040-4039(02)01957-3, ISSN 0040-4039, pages 8153 - 8157, XP004387211 [A] 1-32 * compound 1 *

DOI:   http://dx.doi.org/10.1016/S0040-4039(02)01957-3
by applicantEP0362575
 EP0451760
 WO9204337
 US5591758
 EP1120419
    - MUNZEL T; MOLLNAU H; HARTMANN M ET AL., "Effects of a nitrate-free interval on tolerance, vasoconstrictor sensitivity and vascular superoxide production", J AM COLL CARDIOL., (2000), vol. 36, pages 628 - 634
    - DUVEAU D.Y., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441
    - BREYER, S., CHEM MED CHEM, (2009), vol. 4, no. 5, pages 761 - 768
    - DUVEAU D,Y ET AL., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441
    - KAYASHIMA, TOMOKO ET AL., BIOOR & MED CHEMISTRY, (2010), vol. 18, no. 10, pages 6305 - 6309
    - DUVEAU D. Y., BIOOR & MED CHEMISTRY, (2010), vol. 18, pages 6429 - 6441
    - CHEM MED CHEM, (2009), vol. 4, no. 5, pages 761 - 768
    - BOSCHI D. ET AL., J. MED. CHEM., (2006), vol. 49, pages 2886 - 2897
    - BIOORGANIC & MEDICINAL CHEMISTRY, (2010), vol. 18, pages 6429 - 6441
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.