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Extract from the Register of European Patents

EP About this file: EP2857392

EP2857392 - SMALL COMPOUND TARGETING AT TACC3 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.04.2019
Database last updated on 23.04.2024
FormerThe patent has been granted
Status updated on  11.05.2018
FormerGrant of patent is intended
Status updated on  11.12.2017
FormerExamination is in progress
Status updated on  07.04.2017
Most recent event   Tooltip01.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 03.08.2022  [2022/31]
Applicant(s)For all designated states
Japanese Foundation For Cancer Research
3-8-31, Ariake
Koto-ku
Tokyo 135-8550 / JP
[2015/15]
Inventor(s)01 / YAO, Ryoji
c/o JAPANESE FOUNDATION FOR CANCER RESEARCH
3-8-31 Ariake
Koto-ku
Tokyo 135-8550 / JP
02 / OSADA, Hiroyuki
c/o RIKEN
2-1 Hirosawa
Wako-shi Saitama 351-0198 / JP
03 / KONDOH, Yasumitsu
c/o RIKEN
2-1 Hirosawa
Wako-shi Saitama 351-0198 / JP
 [2015/15]
Representative(s)Schön, Christoph
Dr. Schön, Neymeyr & Partner mbB
Bavariaring 26
80336 München / DE
[2015/15]
Application number, filing date13784486.630.04.2013
[2018/24]
WO2013JP62674
Priority number, dateJP2012010499702.05.2012         Original published format: JP 2012104997
[2015/15]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013165008
Date:07.11.2013
Language:JA
[2013/45]
Type: A1 Application with search report 
No.:EP2857392
Date:08.04.2015
Language:EN
[2015/15]
Type: B1 Patent specification 
No.:EP2857392
Date:13.06.2018
Language:EN
[2018/24]
Search report(s)International search report - published on:JP07.11.2013
(Supplementary) European search report - dispatched on:EP11.03.2016
ClassificationIPC:C07D311/16, A61K31/37, A61K31/4025, A61K31/4433, A61K31/453, A61K31/4545, A61K31/5377, A61K31/55, A61P35/00, A61P35/02, A61P43/00, C07D401/14
[2015/15]
CPC:
C07D405/14 (EP,US); A61K31/37 (EP,US); A61K31/4025 (EP,US);
A61K31/4409 (EP,US); A61K31/445 (EP,US); A61K31/4465 (EP,US);
A61K31/5377 (EP,US); A61P35/00 (EP); A61P35/02 (EP);
A61P43/00 (EP); C07D311/16 (EP,US); C07D401/14 (EP,US);
C07D403/14 (EP,US); C07D407/04 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2015/15]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:KLEINER VERBINDUNG MIT TARGETING VON TACC3[2015/15]
English:SMALL COMPOUND TARGETING AT TACC3[2015/15]
French:PETIT COMPOSÉ CIBLANT LE TACC3[2015/15]
Entry into regional phase02.12.2014Translation filed 
02.12.2014National basic fee paid 
02.12.2014Search fee paid 
02.12.2014Designation fee(s) paid 
02.12.2014Examination fee paid 
Examination procedure02.12.2014Examination requested  [2015/15]
07.09.2016Amendment by applicant (claims and/or description)
06.04.2017Despatch of a communication from the examining division (Time limit: M04)
28.07.2017Reply to a communication from the examining division
12.12.2017Communication of intention to grant the patent
09.04.2018Fee for grant paid
09.04.2018Fee for publishing/printing paid
09.04.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.04.2017
Opposition(s)14.03.2019No opposition filed within time limit [2019/21]
Fees paidRenewal fee
29.04.2015Renewal fee patent year 03
29.03.2016Renewal fee patent year 04
01.05.2017Renewal fee patent year 05
30.04.2018Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.04.2013
AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
MK13.06.2018
MT13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
TR13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
PT15.10.2018
[2022/31]
Former [2021/34]HU30.04.2013
AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
MT13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
TR13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
PT15.10.2018
Former [2021/32]HU30.04.2013
AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
TR13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
PT15.10.2018
Former [2020/29]AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
TR13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
PT15.10.2018
Former [2020/16]AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
TR13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2020/02]AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
MC13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/51]AL13.06.2018
AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/26]AT13.06.2018
CY13.06.2018
CZ13.06.2018
DK13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SI13.06.2018
SK13.06.2018
SM13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/11]AT13.06.2018
CY13.06.2018
CZ13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
IT13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SK13.06.2018
SM13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/10]AT13.06.2018
CY13.06.2018
CZ13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
PL13.06.2018
RO13.06.2018
RS13.06.2018
SE13.06.2018
SK13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/09]CY13.06.2018
EE13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
RS13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/08]CY13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
RS13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
IS13.10.2018
Former [2019/03]CY13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
NL13.06.2018
RS13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
Former [2018/52]CY13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
RS13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
GR14.09.2018
Former [2018/51]CY13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
LV13.06.2018
RS13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
Former [2018/50]CY13.06.2018
ES13.06.2018
FI13.06.2018
HR13.06.2018
LT13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
Former [2018/49]CY13.06.2018
ES13.06.2018
FI13.06.2018
LT13.06.2018
SE13.06.2018
BG13.09.2018
NO13.09.2018
Former [2018/47]ES13.06.2018
FI13.06.2018
LT13.06.2018
NO13.09.2018
Documents cited:Search[A]  - DUBOVIK I P ET AL, "Modified coumarins. 14. Synthesis of 7-hydroxy-[4,3']dichromenyl-2,2'-dione derivatives", CHEMISTRY OF NATURAL COMPOUNDS, KLUWER ACADEMIC PUBLISHERS-CONSULTANTS BUREAU, NE, (20040901), vol. 40, no. 5, ISSN 1573-8388, pages 434 - 443, XP019276620 [A] 1-15 * the whole document *
International search[A]JP2012005479  (JAPAN FOUND CANCER);
 [XP]  - GUASCH, L. ET AL., "Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin(PartI):Virtual Screening and Activity Assays", PLOS ONE, (201209), vol. 7, no. 9, pages 1 - 13, XP055224061

DOI:   http://dx.doi.org/10.1371/journal.pone.0044972
 [X]  - FRASINYUK, M.S. ET AL., "CHEMISTRY OF 3-HETARYLCOUMARINS 3*.SYNTHESIS AND AMINOMETHYLATION OF 7'-HYDROXY-3,4'- BICOUMARINS", KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, (201203), pages 450 - 454, XP055176096

DOI:   http://dx.doi.org/10.1007/s10593-012-1009-z
 [A]  - HALINSKA, A. ET AL., "Cytotoxic mechanisms of anti-tumor quinones in parental and resistant lymphoblasts", BRITISH JOURNAL OF CANCER, (1996), vol. 74, no. SUPPL., pages S23 - S27, XP055176098
by applicantWO2005071419
 JP2009167163
 JP2012005479
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    - SUDAKIN, V.; YEN, T.J., BIODRUGS, (2007), vol. 21, pages 225 - 33
    - CHARRASSE, S. ET AL., EUR. J. BIOCHEM., (1995), vol. 234, no. 2, pages 406 - 413
    - KIEMENEY, L.A. ET AL., NAT. GENET., (2010), vol. 42, no. 5, pages 415 - 419
    - PETERS, D.G. ET AL., CANCER EPIDEMIOL. BIOMARKERS PREV., (2005), vol. 14, no. 7, pages 1717 - 1723
    - MA, X.J. ET AL., PROC. NATL. ACAD. SCI. USA, (2003), vol. 100, no. 10, pages 5974 - 5979
    - ULISSE, S. ET AL., ENDOCR. RELAT. CANCER, (2007), vol. 14, no. 3, pages 827 - 837
    - STILL, I.H. ET AL., GENOMICS, (1999), vol. 58, no. 2, pages 165 - 170
    - SCHNEIDER, L. ET AL., ONCOGENE, (2008), vol. 27, no. 1, pages 116 - 125
    - GERGELY, F. ET AL., GENES DEV., (2003), vol. 17, pages 336 - 341
    - PESET, I.; VERNONS, I., TRENDS CELL BIOL., (2008), vol. 18, no. 8, pages 379 - 388
    - YAO, R. ET AL., ONCOGENE, (2012), vol. 31, pages 135 - 148
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.