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Extract from the Register of European Patents

EP About this file: EP3204358

EP3204358 - CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.07.2019
Database last updated on 22.01.2025
FormerThe patent has been granted
Status updated on  17.08.2018
FormerGrant of patent is intended
Status updated on  22.03.2018
FormerRequest for examination was made
Status updated on  14.07.2017
FormerThe international publication has been made
Status updated on  01.03.2017
Most recent event   Tooltip03.07.2020Lapse of the patent in a contracting state
New state(s): CY, HU, MK		published on 05.08.2020  [2020/32]
Applicant(s)For all designated states
Vertex Pharmaceuticals Incorporated
50 Northern Avenue
Boston, MA 02210 / US
[2017/33]
Inventor(s)01 / STROHMEIER, Mark
103 Westmoreland Avenue
Arlington, MA 02474 / US
02 / CAESAR, JR., John P.
50 Otis Street
Lancaster, MA 01523 / US
03 / CONNELLY, Patrick Raymond
15 Lovers Lane
Harvard, MA 01451 / US
04 / FAWAZ, Majed
135 North Street
Foxboro, MA 02035 / US
05 / LUSS-LUSIS, Eduard
90 Brighton Street
Belmont, MA 02478 / US
06 / MCCLAIN, Brian R.
23 Deerfoot Trail
Harvard, MA 01451 / US
07 / MEDEK, Ales
14 Lockland Road
Winchester, MA 01890 / US
08 / MIAO, Hai
15 Buckman Drive
Winchester, MA 01890 / US
09 / NTI-ADDAE, Kwame Wiredu
19 Kensington Way
Tewksbury, MA 01876 / US
10 / YIN, Ping
26 Cypress Road
Arlington, MA 02474 / US
11 / ZHANG, Yuegang
15 Fairfield Road
Wayland, MA 01778 / US
 [2018/38]
Former [2017/33]01 / STROHMEIER, Mark
103 Westmoreland Avenue
Arlington, Massachusetts 02474 / US
02 / CAESAR, Jr. John P.
50 Otis Street
Lancaster, Massachusetts 01523 / US
03 / CONNELLY, Patrick Raymond
15 Lovers Lane
Harvard, Massachusetts 01451 / US
04 / FAWAZ, Majed
135 North Street
Foxboro, Massachusetts 02035 / US
05 / LUSS-LUSIS, Eduard
90 Brighton Street
Belmont, Massachusetts 02478 / US
06 / MCCLAIN, Brian R.
23 Deerfoot Trail
Harvard, Massachusetts 01451 / US
07 / MEDEK, Ales
14 Lockland Road
Winchester, Massachusetts 01890 / US
08 / MIAO, Hai
15 Buckman Drive
Winchester, Massachusetts 01890 / US
09 / NTI-ADDAE, Kwame Wiredu
19 Kensington Way
Tewksbury, Massachusetts 01876 / US
10 / YIN, Ping
26 Cypress Road
Arlington, Massachusetts 02474 / US
11 / ZHANG, Yuegang
15 Fairfield Road
Wayland, Massachusetts 01778 / US
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2017/33]
Application number, filing date15849070.607.10.2015
[2017/33]
WO2015US54577
Priority number, dateUS201462060828P07.10.2014         Original published format: US 201462060828 P
[2017/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016057730
Date:14.04.2016
Language:EN
[2016/15]
Type: A1 Application with search report 
No.:EP3204358
Date:16.08.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.2016 takes the place of the publication of the European patent application.
[2017/33]
Type: B1 Patent specification 
No.:EP3204358
Date:19.09.2018
Language:EN
[2018/38]
Search report(s)International search report - published on:US14.04.2016
(Supplementary) European search report - dispatched on:EP05.07.2017
ClassificationIPC:C07D215/56, A61K31/4704, A61P11/00
[2017/33]
CPC:
C07D215/56 (EP,KR,RU,US); A61K31/225 (EP,US); A61K31/4418 (RU);
A61K31/47 (EP,KR,US); A61K45/06 (US); A61P11/00 (EP,RU);
A61P27/04 (EP); A61P43/00 (EP); C07C69/18 (EP,US);
C07C69/30 (EP,US); C07C69/34 (US); C07C69/58 (EP,US);
C07C69/587 (EP,US); C07B2200/13 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/33]
Extension statesBA08.05.2017
ME08.05.2017
Validation statesMA08.05.2017
TitleGerman:COKRISTALLE VON MODULATOREN DES TRANSMEMBRANKONDUKTANZREGULATORS BEI ZYSTISCHER FIBROSE[2017/33]
English:CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR[2017/33]
French:CO-CRISTAUX DE MODULATEURS DU RÉGULATEUR DE CONDUCTANCE TRANSMEMBRANAIRE DE LA MUCOVISCIDOSE[2017/33]
Entry into regional phase08.05.2017National basic fee paid 
08.05.2017Search fee paid 
08.05.2017Designation fee(s) paid 
08.05.2017Examination fee paid 
Examination procedure08.05.2017Examination requested  [2017/33]
08.05.2017Date on which the examining division has become responsible
30.01.2018Amendment by applicant (claims and/or description)
23.03.2018Communication of intention to grant the patent
02.08.2018Fee for grant paid
02.08.2018Fee for publishing/printing paid
02.08.2018Receipt of the translation of the claim(s)
Opposition(s)20.06.2019No opposition filed within time limit [2019/35]
Fees paidRenewal fee
11.10.2017Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU07.10.2015
AL19.09.2018
AT19.09.2018
CY19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
MK19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SK19.09.2018
SM19.09.2018
TR19.09.2018
LU07.10.2018
MT07.10.2018
CH31.10.2018
LI31.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
[2020/31]
Former [2020/17]AL19.09.2018
AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SK19.09.2018
SM19.09.2018
TR19.09.2018
LU07.10.2018
MT07.10.2018
CH31.10.2018
LI31.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2020/08]AL19.09.2018
AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
MT07.10.2018
CH31.10.2018
LI31.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/50]AL19.09.2018
AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SI19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
CH31.10.2018
LI31.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/40]AL19.09.2018
AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
CH31.10.2018
LI31.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/34]AL19.09.2018
AT19.09.2018
CZ19.09.2018
DK19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/33]AL19.09.2018
AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
MC19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/30]AL19.09.2018
AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
SM19.09.2018
LU07.10.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/26]AL19.09.2018
AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
SM19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
PT19.01.2019
Former [2019/23]AL19.09.2018
AT19.09.2018
CZ19.09.2018
EE19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
SK19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/22]AL19.09.2018
CZ19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
PL19.09.2018
RO19.09.2018
RS19.09.2018
SE19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/21]AL19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RS19.09.2018
SE19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
IS19.01.2019
Former [2019/12]AL19.09.2018
FI19.09.2018
HR19.09.2018
LT19.09.2018
LV19.09.2018
RS19.09.2018
SE19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
Former [2019/11]FI19.09.2018
HR19.09.2018
LT19.09.2018
RS19.09.2018
SE19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
Former [2019/10]FI19.09.2018
LT19.09.2018
RS19.09.2018
SE19.09.2018
BG19.12.2018
NO19.12.2018
GR20.12.2018
Former [2019/08]FI19.09.2018
LT19.09.2018
NO19.12.2018
Former [2019/07]LT19.09.2018
Documents cited:Search   [ ] - No further relevant documents disclosed
International search[A]US2009105272  (GROOTENHUIS PETER D J [US], et al) [A] 1-7, 11-15, 21 * entire document *;
 [A]US7553855  (YOUNG CHRISTOPHER R [US], et al) [A] 1-7, 11-15, 21* entire document *;
 [A]WO2011133953  (VERTEX PHARMA [US], et al) [A] 1-7, 11-15, 21 * entire document *;
 [A]US2012214841  (HURTER PATRICIA [US], et al) [A] 1-7, 11-15, 21 * entire document *;
 [A]WO2014118805  (GLENMARK PHARMACEUTICALS LTD ; GLENMARK GENERICS LTD [IN]) [A] 1-7, 11-15, 21 * entire document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.