Extract from the Register of European Patents

About this file: EP3466923

EP3466923 - PROCESS FOR THE PREPARATION OF AGOMELATINE IN CRYSTALLINE FORM [Right-click to bookmark this link]
StatusThe application has been published
Status updated on  08.03.2019
Database last updated on 14.09.2019
Most recent event   Tooltip08.03.2019Publication in section I.1 EP Bulletinpublished on 10.04.2019  [2019/15]
Applicant(s)For all designated states
KRKA, d.d., Novo mesto
Smarjeska cesta 6
8501 Novo mesto / SI
[2019/15]
Inventor(s)01 / Kidemet, Davor
Krizaniceva 55
42000 Varazdin / HR
02 / Gosak, Kaja
Podjavorskova 3
3000 Celje / SI
03 / Zupancic, Blaz
Skerljeva 11
1000 Lubljana / SI
04 / Benkic, Primoz
Vodovodna 46A
1000 Lubljana / SI
05 / Pavlin, Darja
Potok 5b
8351 Straza pri Novem mestu / SI
06 / Kolenc, Ivanka
Ulica Slavka Gruma 9
8000 Novo mesto / SI
 [2019/15]
Representative(s)Hoefer & Partner Patentanwälte mbB
Pilgersheimer Straße 20
81543 München / DE
[2019/15]
Application number, filing date17195494.409.10.2017
[2019/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3466923
Date:10.04.2019
Language:EN
[2019/15]
Search report(s)(Supplementary) European search report - dispatched on:EP27.03.2018
ClassificationInternational:C07C231/12, C07C231/24, C07C233/18
[2019/15]
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/15]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON AGOMELATIN IN KRISTALLINER FORM[2019/15]
English:PROCESS FOR THE PREPARATION OF AGOMELATINE IN CRYSTALLINE FORM[2019/15]
French:PROCÉDÉS DE PRÉPARATION D'AGOMÉLATINE DANS UNE FORME CRISTALLINE[2019/15]
Documents cited:Search[XDY]EP2474522  (TIANJIN TAIPU PHARMACEUTICAL SCI & TECH DEV CO LTD [CN]) [XD] 14,15 * claims 1, 2 * * columns 9-10; examples 1-6 * [Y] 1-13;
 [XD]WO2011154140  (GADOR SA [AR]; CONICET CONSEJO NAC DE INVESTIGACIONES CIENTIFICAS Y TE) [XD] 14,15 * claim 20 * * page 15; example 10 *;
 [X]CN101955440B  (BEIJING DVENTUREPHARM TECHNOLOGY DEV CO LTD) [X] 14,15 * claim 1 * * paragraph [0019] * * figure 2 *;
 [XDYI]EP2690087  (SERVIER LAB [FR]; SHANGHAI INST PHARM INDUSTRY [CN]) [XD] 14,15 * claims 1, 7, 8 * * figure 2 * * embodiments 1-3; page 5 * [Y] 1-13 [I] 1-13;
 [XY]US2014088197  (HUANG YU [CN] ET AL) [X] 14,15 * claim 15 * * figures 2, 4, 6 * * embodiments 1-3; page 5 * [Y] 1-13;
 [A]CN103623423  (JIANG AIFANG) [A] 1-15 * page 4, paragraph 0005 *
 [X]  - JAN HOLAN ET AL, "Polymorphic Crystallization and Structural Aspects of Agomelatine Metastable Form X Prepared by Combined Antisolvent/Cooling Process", ORGANIC PROCESS RESEARCH AND DEVELOPMENT, US, (20151217), vol. 20, no. 1, doi:10.1021/acs.oprd.5b00241, ISSN 1083-6160, pages 33 - 43, XP055458385 [X] 14,15 * page 34, column 2, lines 30-37 * * page 35, paragraph 2.4 * * page 36; figure 2 *

DOI:   http://dx.doi.org/10.1021/acs.oprd.5b00241
by applicantEP0447285
 EP1752444
 EP1752443
 EP2058296
 EP2690087
 EP2474522
 WO2011154140
 EP2474522
 EP1564202
    - FURTHERMORE, Asian Journal of Pharmaceutical Sciences, (20130000), vol. 8, pages 181 - 190