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Extract from the Register of European Patents

EP About this file: EP4077710

EP4077710 - METHODS AND COMPOSITIONS FOR MONITORING AND DIAGNOSING HEALTHY AND DISEASE STATES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  23.09.2022
Database last updated on 11.11.2024
FormerThe international publication has been made
Status updated on  25.06.2021
Most recent event   Tooltip04.11.2024The date on which the examining division becomes responsible, has been established 
04.11.2024Amendment by applicant 
04.11.2024New entry: Receipt of request for further processing 
04.11.2024New entry: Fee payment for request for further processing 
Applicant(s)For all designated states
University of Utah Research Foundation
615 Arapeen Drive
Suite 310
Salt Lake City, UT 84108 / US
For all designated states
Duke University
2812 Erwin Road Suite 206
Durham, North Carolina 27705 / US
[2022/43]
Inventor(s)01 / ROWLEY, Jesse, Worth
c/o 201 University of Utah
201 President's Circle
Salt Lake City, UT 84112 / US
02 / RONDINA, Matthew
c/o 201 University of Utah
201 President's Circle
Salt Lake City, UT 84112 / US
03 / VOORA, Deepak
c/o Duke University School of Medicine 101
Science Dr. 2187 Ciemas, Campus Box 3382
Durham, NC 27708 / US
 [2022/43]
Representative(s)CH Kilger Anwaltspartnerschaft mbB
Fasanenstraße 29
10719 Berlin / DE
[2022/43]
Application number, filing date20902974.318.12.2020
[2022/43]
WO2020US66190
Priority number, dateUS201962951004P20.12.2019         Original published format: US 201962951004 P
[2022/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021127549
Date:24.06.2021
Language:EN
[2021/25]
Type: A1 Application with search report 
No.:EP4077710
Date:26.10.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 24.06.2021 takes the place of the publication of the European patent application.
[2022/43]
Search report(s)International search report - published on:US24.06.2021
(Supplementary) European search report - dispatched on:EP23.01.2024
ClassificationIPC:C12Q1/6809, G01N33/53, C12M3/00, C12N5/071, C40B40/08, B01D59/44
[2024/08]
CPC:
C12Q1/6809 (EP,KR,US); C12Q1/6883 (EP,KR); C12N5/0644 (EP,KR);
C12Q1/6837 (US); C12Q1/6869 (US); C40B40/08 (EP,KR);
G01N33/5308 (US); G01N33/86 (EP); G16B20/00 (US);
C12Q1/6886 (EP); C12Q2600/156 (KR); C12Q2600/158 (EP,KR,US);
C12Q2600/166 (US); G01N2800/222 (EP,US) (-)
Former IPC [2022/43]C12Q1/68, G01N33/53, C12M3/00, C12N5/071, C40B40/08, B01D59/44
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/43]
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR ÜBERWACHUNG UND DIAGNOSE VON GESUNDEN UND KRANKHAFTEN ZUSTÄNDEN[2022/43]
English:METHODS AND COMPOSITIONS FOR MONITORING AND DIAGNOSING HEALTHY AND DISEASE STATES[2022/43]
French:PROCÉDÉS ET COMPOSITIONS POUR LE SUIVI ET LE DIAGNOSTIC DES ÉTATS DE SANTÉ ET DE MALADIES[2022/43]
Entry into regional phase20.07.2022National basic fee paid 
20.07.2022Search fee paid 
20.07.2022Designation fee(s) paid 
20.07.2022Examination fee paid 
Examination procedure20.10.2021Request for preliminary examination filed
International Preliminary Examining Authority: US
20.07.2022Examination requested  [2022/43]
04.09.2024Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
04.11.2024Amendment by applicant (claims and/or description)
04.11.2024Date on which the examining division has become responsible
Request for further processing for:The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
04.11.2024Request for further processing filed
04.11.2024Full payment received (date of receipt of payment)
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
04.11.2024Request for further processing filed
04.11.2024Full payment received (date of receipt of payment)
Fees paidRenewal fee
20.07.2022Renewal fee patent year 03
27.12.2023Renewal fee patent year 04
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Documents cited:Search[A]US2019360051  (WÜRDINGER THOMAS [NL], et al) [A] 1-15 * the whole document *;
 [X]  - RONDINA MATTHEW T. ET AL, "Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL", CIRCULATION RESEARCH, US, vol. 126, no. 4, doi:10.1161/CIRCRESAHA.119.315215, ISSN 0009-7330, (20191219), pages 501 - 516, URL: https://www.ahajournals.org/history/2db2d84c-67a4-4d53-8f4c-6acf7f547478/10.1161_circresaha.119.315215_7478.pdf, XP093110770 [X] 1-15 * abstract; p. 5; p. 7, 5th para. - p 8, 2nd para.; p. 11, 2nd-4th para.; fig. 1, 2 *

DOI:   http://dx.doi.org/10.1161/CIRCRESAHA.119.315215
    [ ] - RONDINA MATTHEW T ET AL, "Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELPSplice QTL.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, (20191219), Database accession no. NLM31852401, XP002810697 [ ] * abstract *
 [X]  - ROWLEY JESSE W ET AL, "Transcript Expression, Intron Retention, and RNA Editing Are Conserved in Human Platelets over a 4 Year Period", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20171208), vol. 130, doi:10.1182/BLOOD.V130.SUPPL_1.456.456, ISSN 0006-4971, page 456, XP086635050 [X] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1182/blood.V130.Suppl_1.456.456
 [X]  - BRAY PAUL F ET AL, "High-Throughput Sequencing of the Human Platelet Transcriptome", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20101101), vol. 116, no. 21, ISSN 0006-4971, page 214, XP009191689 [X] 1 * abstract *
 [A]  - GNATENKO DMITRI V ET AL, "Platelet Gene/Protein expression analyses using an integrated platform", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20071101), vol. 110, no. 11, ISSN 0006-4971, page 1065A, XP009186217 [A] 1-15 * the whole document *
 [A]  - BEST MYRON G ET AL, "RNA sequencing and swarm intelligence-enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA", NATURE PROTOCOLS, NATURE PUBLISHING GROUP, GB, vol. 14, no. 4, doi:10.1038/S41596-019-0139-5, ISSN 1754-2189, (20190320), pages 1206 - 1234, (20190320), XP036742119 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/s41596-019-0139-5
International search[Y]US2018357379  (KOH LIAN CHYE WINSTON [US], et al) [Y] 7, 8/(7), 13, 15 * , para [0006], [0010], [0024], [0027], [0042], [0058], [0060], [0076], and [0092] *;
 [A]US2019083593  (SAHIN UGUR [DE], et al) [A] 1-15 * , para [0022], [0040]-0045], [0052], [0060], [0061], [0139], and [0141] *;
 [XY]  - John D Eicher, Yoshiyuki Wakabayashi, Olga Vitseva, Nada Esa, Yanqin Yang, Jun Zhu, Jane E Freedman, David D McManus, Andrew D Johnson, "Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction", Platelets (London), GB, (20151130), vol. 27, no. 3, doi:10.3109/09537104.2015.1083543, ISSN 0953-7104, pages 230 - 239, XP009529809 [X] 1-6, 8/(1-6), 9-12, 14 * . PDF File: pg 1-23. Abstract; pg 2, para 2 and last para; pg 3, para 1, para 2, and last para; pg 4, para 1, para 2, and last para; pg 5, para 2; pg 7, last para; pg 19, Table II; pg 20, Table III; and pg 21, Table IV * [Y] 7, 8/(7), 13, 15

DOI:   http://dx.doi.org/10.3109/09537104.2015.1083543
 [A]  - Zhang Qun, Hu Huan, Liu Hongda, Jin Jiajia, Zhu Peiyuan, Wang Shujun, Shen Kaikai, Hu Yangbo, Li Zhou, Zhan Ping, Zhu Suhua, Fan Hang, Zhang Jianya, Lv Tangfeng, Song Yong, "RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients", Biomedicine & Pharmacotherapy, ELSEVIER, FR, FR, (20180901), vol. 105, doi:10.1016/j.biopha.2018.05.074, ISSN 0753-3322, pages 204 - 214, XP055837424 [A] 1-15 * . Entire documentation especially Abstract; pg 205, col 1, para 2, para 3, and last para; pg 206, Fig 1; pg 207, Table 2; pg 208, Table 3; pg 209, Fig 3, and Table 4; and pg 210, Fig 4 *

DOI:   http://dx.doi.org/10.1016/j.biopha.2018.05.074
 [A]  - Sá Ana Caroline C., Sadee Wolfgang, Johnson Julie A., "Whole Transcriptome Profiling: An RNA-Seq Primer and Implications for Pharmacogenomics Research : RNA-Seq for Pharmacogenomics Research", CTS - CLINICAL AND TRANSLATIONAL SCIENCE, WileyBlackwell Pub., US, US, (20180301), vol. 11, no. 2, doi:10.1111/cts.12511, ISSN 1752-8054, pages 153 - 161, XP055837425 [A] 1-15 * . Entire documentation especially Introduction; pg 154, col 2, last para, and Table 1; pg 155, Fig 2; and pg 156, Fig 3 *

DOI:   http://dx.doi.org/10.1111/cts.12511
 [A]  - Best Myron G.; Sol Nik; In ‘t Veld Sjors G.J.G.; Vancura Adrienne; Muller Mirte; Niemeijer Anna-Larissa N.; Fejes Aniko V.; Tjon Kon Fat Lee-Ann; Huis In ‘t Veld Anna E.; Leurs Cyra; Le Large Tessa Y.; Meijer Laura L.; Kooi Irsan E.; Rustenburg François; Schellen Pepijn; Verschueren Heleen; Post Edward; Wedekind Laurine E.; Bracht Jillian; Esenkbrink Michelle; Wils Leon; Favaro Francesca; Schoonhoven Jilian D.; Tannous Jihane; Meijers-Heijboer Hanne; Kazemier Geert; Giovannetti Elisa; Reijneveld Jaap C.; Idema Sander; Killestein Joep; Heger Michal; de Jager Saskia C.; Urbanus Rolf T.; Hoefer Imo E.; Pasterkamp Gerard; Mannhalter Christine; Gomez-Arroyo Jose; Bogaard Harm-Jan; Noske David P.; Vandertop W. Peter; van den Broek Daan; Ylstra Bauke; Nilsson R. Jonas A.; Wesseling Pieter; Karachaliou Niki; Rosell Rafael; Lee-Lewandrowski Elizabeth; Lewandrowski Kent B.; Tannous Bakhos A.; de Langen Adrianus J.; Smit Egbert F.; van den Heuvel Michel M.; Wurdinger Thomas, "Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets", CANCER CELL, CELL PRESS, US, US, (20170814), vol. 32, no. 2, doi:10.1016/j.ccell.2017.07.004, ISSN 1535-6108, page 238, XP085156266 [A] 1-15 * . Entire documentation especially Summary; Graphical Abstract; and pg 6, para 3 *

DOI:   http://dx.doi.org/10.1016/j.ccell.2017.07.004
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.