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EP4024028
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| EP4024028 - PREDICTION OF THERAPEUTIC RESPONSE USING VIBRATIONAL SPECTROSCOPY [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 26.05.2023 Database last updated on 22.01.2025 | |
| Former | The application has been published Status updated on 03.06.2022 | Most recent event Tooltip | 26.05.2023 | Application deemed to be withdrawn | published on 28.06.2023 [2023/26] | Applicant(s) | For all designated states Technological University Dublin Park House Grangegorman 191 North Circular Road Dublin D07 EWV4 / IE | [2022/27] | Inventor(s) | 01 /
LYNG, Fiona 8 Dublin / IE | 02 /
MAGUIRE, Adrian 8 Dublin / IE | 03 /
MEADE, Aidan 8 Dublin / IE | 04 /
VEGA CARRASCAL, Isabel 8 Dublin / IE | 05 /
WHITE, Lisa 8 Dublin / IE | 06 /
HOWE, Orla 8 Dublin / IE | [2022/27] | Representative(s) | Murgitroyd & Company 165-169 Scotland Street Glasgow G5 8PL / GB | [N/P] |
| Former [2022/27] | Murgitroyd & Company Murgitroyd House 165-169 Scotland Street Glasgow G5 8PL / GB | Application number, filing date | 21216009.7 | 20.12.2016 | [2022/27] | Priority number, date | GB20150022557 | 21.12.2015 Original published format: GB 201522557 | [2022/27] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP4024028 | Date: | 06.07.2022 | Language: | EN | [2022/27] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 03.06.2022 | Classification | IPC: | G01N21/00, G01N33/483 | [2022/27] | CPC: |
G01N33/4833 (EP,US);
G01N33/50 (GB);
A61N5/103 (US);
G01N21/3563 (US);
G01N21/3577 (US);
G01N21/65 (EP,GB,US);
G01N33/49 (EP,US);
G01N33/54366 (EP,US);
G01N33/574 (EP,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2022/27] | Title | German: | VORHERSAGE DER THERAPEUTISCHEN REAKTION MITHILFE VON VIBRATIONSSPEKTROSKOPIE | [2022/27] | English: | PREDICTION OF THERAPEUTIC RESPONSE USING VIBRATIONAL SPECTROSCOPY | [2022/27] | French: | PRÉDICTION D'UNE RÉPONSE THÉRAPEUTIQUE EN UTILISANT LA SPECTROSCOPIE VIBRATOIRE | [2022/27] | Examination procedure | 10.01.2023 | Application deemed to be withdrawn, date of legal effect [2023/26] | 07.02.2023 | Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time [2023/26] | Parent application(s) Tooltip | EP16826718.5 / EP3394593 | Fees paid | Renewal fee | 20.12.2021 | Renewal fee patent year 03 | 20.12.2021 | Renewal fee patent year 04 | 20.12.2021 | Renewal fee patent year 05 | 20.12.2021 | Renewal fee patent year 06 | Penalty fee | Additional fee for renewal fee | 31.12.2022 | 07 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XY]WO2013001507 (KONINKL PHILIPS ELECTRONICS NV [NL], et al) [X] 1-8,12,13,15 * figures 1, 12; claims 1-30 * [Y] 1-15; | [Y] - NOTINGHER IOAN ET AL, "Discrimination between ricin and sulphur mustard toxicity in vitro using Raman spectroscopy", JOURNAL OF THE ROYAL SOCIETY. INTERFACE, GB, vol. 1, no. 1, doi:10.1098/rsif.2004.0008, ISSN 1742-5689, (20041122), pages 79 - 90, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618929/pdf/16849154.pdf, XP055921932 [Y] 1-15 * abstract * DOI: http://dx.doi.org/10.1098/rsif.2004.0008 | [Y] - MAGUIRE A. ET AL, "Analyses of Ionizing Radiation Effects In Vitro in Peripheral Blood Lymphocytes with Raman Spectroscopy", RADIATION RESEARCH, US, vol. 183, no. 4, doi:10.1667/RR13891.1, ISSN 0033-7587, (20150401), pages 407 - 416, URL: http://dx.doi.org/10.1667/RR13891.1, XP055922225 [Y] 1-15 * the whole document * DOI: http://dx.doi.org/10.1667/RR13891.1 | by applicant | - LIEVENS, Y.GRAU, C., "Health economics in radiation oncology: introducing the ESTRO HERO project", Radiother. Oncol., (20120000), vol. 103, pages 109 - 12 | - ROSENBLATT, E. et al., "Radiotherapy capacity in European countries: an analysis of the Directory of Radiotherapy Centres (DIRAC) database", Lancet. Oncol., (20130000), vol. 14, pages 79 - 86 | - REYNOLDS, J. V. et al., "Long-term outcomes following neoadjuvant chemoradiotherapy for esophageal cancer", Ann. Surg., (20070000), vol. 245, pages 707 - 16 | - THOMPSON, A. M.MOULDER-THOMPSON, S. L, Ann. Oncol., (20120000), vol. 23, pages 231 - 6 | - LUDWIG, J. A.WEINSTEIN, J. N, "Biomarkers in cancer staging, prognosis and treatment selection", Nat. Rev. Cancer, (20050000), vol. 5, doi:10.1038/nrc1739, pages 845 - 56, XP055005637 DOI: http://dx.doi.org/10.1038/nrc1739 | - BIBAULT, J.-E et al., "Personalized radiation therapy and biomarker-driven treatment strategies: a systematic review", Cancer Metastasis Rev., (20130000), vol. 32, doi:10.1007/s10555-013-9419-7, pages 479 - 92, XP035326386 DOI: http://dx.doi.org/10.1007/s10555-013-9419-7 | - KRAUSE, D. SVAN ETTEN, R. A, "Tyrosine kinases as targets for cancer therapy", N. Engl. J. Med, (20050000), vol. 353, pages 172 - 87 | - VAN'T VEER, L. J.BERNARDS, R., "Enabling personalized cancer medicine through analysis of gene-expression patterns", Nature, (20080000), vol. 452, doi:10.1038/nature06915, pages 564 - 70, XP002664142 DOI: http://dx.doi.org/10.1038/nature06915 | - VAN DE VIJVER, M. J., "A gene-expression signature as a predictor of survival in breast cancer ", N. Engl. J. Med., (20020000), vol. 347, doi:10.1056/NEJMoa021967, pages 1999 - 2009, XP008032093 DOI: http://dx.doi.org/10.1056/NEJMoa021967 | - ROSELL, R.BIVONA, T. G.KARACHALIOU, N, "Genetics and biomarkers in personalisation of lung cancer treatment", Lancet, (20130000), vol. 382, doi:10.1016/S0140-6736(13)61715-8, pages 720 - 31, XP055098533 DOI: http://dx.doi.org/10.1016/S0140-6736(13)61715-8 | - MULRANE, L.REXHEPAJ, E.PENNEY, S.CALLANAN, J. J.GALLAGHER, W. M, "Automated image analysis in histopathology: a valuable tool in medical diagnostics", Expert Rev. Mol. Diagn., (20080000), vol. 8, pages 707 - 25 | - BRENNAN, D. J.O'CONNOR, D. P.REXHEPAJ, E.PONTEN, F.GALLAGHER, W. M., "Antibody-based proteomics: fast-tracking molecular diagnostics in oncology", Nat. Rev. Cancer, (20100000), vol. 10, doi:10.1038/nrc2902, pages 605 - 17, XP055144014 DOI: http://dx.doi.org/10.1038/nrc2902 | - KLEIN, M. E. et al., "Prediction of the Oncotype DX recurrence score: use of pathology-generated equations derived by linear regression analysis.", Mod. Pathol., (20130000), vol. 26, doi:10.1038/modpathol.2013.36, pages 658 - 64, XP055759430 DOI: http://dx.doi.org/10.1038/modpathol.2013.36 | - KRAUS, J. A.DABBS, D. J.BERIWAL, S.BHARGAVA, R, "Semi-quantitative immunohistochemical assay versus oncotype DX(*)) qRT-PCR assay for estrogen and progesterone receptors: an independent quality assurance study", Mod. Pathol., (20120000), vol. 25, pages 869 - 76 | - WISTUBA, 1. 1.GELOVANI, J. G.JACOBY, J. J.DAVIS, S. E.HERBST, R. S, "Methodological and practical challenges for personalized cancer therapies", Nat Rev Clin Oncol, (20110000), vol. 8, pages 135 - 141 | - HAIBE-KAINS, B. et al., "Inconsistency in large pharmacogenomic studies", Nature, (20130000), vol. 504, doi:10.1038/nature12831, pages 389 - 393, XP037500800 DOI: http://dx.doi.org/10.1038/nature12831 | - HUBER, F. et al., "Comprehensive validation of published immunohistochemical prognostic biomarkers of prostate cancer-what has gone wrong? A blueprint for the way forward in biomarker studies", Br. J. Cancer, (20150000), vol. 112, pages 140 - 8 | - BERG, R. W.NORBYGAARD. T, "Wavenumber Calibration of CCD Detector Raman Spectrometers Controlled by a Sinus Arm Drive", Appl. Spectrosc. Rev., (20060000), vol. 41, pages 165 - 183 | - MAZET, V.CARTERET, C.BRIE, D.IDLER, JHUMBERT, B., "Background removal from spectra by designing and minimising a non-quadratic cost function", Chemom. Intell. Lab. Syst., (20050000), vol. 76, doi:10.1016/j.chemolab.2004.10.003, pages 121 - 133, XP025287580 DOI: http://dx.doi.org/10.1016/j.chemolab.2004.10.003 | - BAKER, M. J. et al., "Using Fourier transform IR spectroscopy to analyze biological materials", Nat. Protoc., (20140000), vol. 9, doi:10.1038/nprot.2014.110, pages 1771 - 91, XP037159831 DOI: http://dx.doi.org/10.1038/nprot.2014.110 | - CLUPEK, M.MATEJKA, P.VOLKA, K, "Noise reduction in Raman spectra: Finite impulseresponse filtration versus Savitzky-Golay smoothing", J. Raman Spectrosc., (20070000), vol. 38, pages 1174 - 1179 | - KELLER, M. D.KANTER, E. MMAHADEVAN-JANSEN, A, "Raman Spectroscopy for Cancer Diagnosis", spectroscopy, (20060000), vol. 21 | - KANTER, E. M. et al., "Application of Raman spectroscopy for cervical dysplasia diagnosis", J. Biophotonics, (20090000), vol. 2, pages 81 - 90 | - KANTER, E. M. et al., "Multiclass discrimination of cervical precancers using Raman spectroscopy", J. Raman Spectrosc., (20090000), vol. 40, pages 205 - 211 | - SAVITZKY, A.GOLAY, M. J. E, "Smoothing and Differentiation of Data by Simplified Least Squares Procedures", Anal. Chem., (19640000), vol. 36, doi:10.1021/ac60214a047, pages 1627 - 1639, XP000560623 DOI: http://dx.doi.org/10.1021/ac60214a047 | - MATTHEWS, Q.BROLO, ALUM, J.DUAN, X.JIRASEK, A., "Raman spectroscopy of single human tumour cells exposed to ionizing radiation in vitro", Phys. Med. Biol., (20110000), vol. 56, pages 19 - 38, XP020185763 | - KATAINEN, E. et al., "Quantification of the amphetamine content in seized street samples by Raman spectroscopy", J. Forensic Sci., (20070000), vol. 52, pages 88 - 92 | - VILLASANA, L.DAYGER, C.RABER, J, "Dose- and ApoE Isoform-Dependent Cognitive Injury after Cranial (56)Fe Irradiation in Female Mice", Radiat. Res., (20130000), vol. 179, pages 493 - 500 | - ACEVEDO, S. E.MCGINNIS, GRABER, J, "Effects of 137Cs gamma irradiation on cognitive performance and measures of anxiety in Apoe-/- and wild-type female mice", Radiat. Res., (20080000), vol. 170, pages 422 - 8 | - VILLASANA, L.ACEVEDO, S.POAGE, C.RABER, J., "Sex- and APOE isoform-dependent effects of radiation on cognitive function", Radiat. Res., (20060000), vol. 166, pages 883 - 891 | - RENDLEMAN, J. et al., "Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma", PLoS One, (20140000), vol. 9, page el01685 | - JUSTICE, TMARTENSON, J.WISEMAN, G.WITZIG, T, "afety and efficacy of external beam radiation therapy for non-Hodgkin lymphoma in patients with prior 90Y-ibritumomab tiuxetan radioimmunotherapy", Cancer, (20060000), vol. 107, pages 433 - 438 | - JAIME GARCIA, H, "Chromosomal sensitivity to X-rays in lymphocytes from patients with Turner syndrome", Mutat. Res., (19860000), vol. 160, pages 33 - 38 | - SARASWATHY, R.MEENA, J.MARIMUTHU, K., "THE IMPORTANCE OF THE STUDY OF RADIOSENSITIVITY IN HUMAN GENETIC DISORDERS", Int. J. Pharma Bio Sci., (20120000), vol. 3, pages 689 - 697 | - STONE, N.KENDAL, 1 C.SMITH, J.CROW, PBARR, H., "Raman spectroscopy for identification of epithelial cancers", Faraday Discuss, (20040000), pages 141 - 57 | - NOTINGHER, I. et al., "Discrimination between ricin and sulphur mustard toxicity in vitro using Raman spectroscopy", J. R. Soc. Interface, (20040000), vol. 1, pages 79 - 90 | - KRAFFT, C.NEUDERT, LSIMAT, T.SALZER, R, Spectrochim. Acta. A. Mol. Biomol. Spectrosc, (20050000), vol. 61, pages 1529 - 35 | - HUANG, Z. et al., "Near-infrared Raman spectroscopy for optical diagnosis of lung cancer.", Int. J. Cancer, (20030000), vol. 107, doi:10.1002/ijc.11500, pages 1047 - 52, XP055716563 DOI: http://dx.doi.org/10.1002/ijc.11500 | - CHENG, W.-TLIU, M.-T.LIU, H.-N.LIN, S.-Y, "Micro-Raman spectroscopy used to identify and grade human skin pilomatrixoma", Microsc. Res. Tech., (20050000), vol. 68, doi:10.1002/jemt.20229, pages 75 - 9, XP002453886 DOI: http://dx.doi.org/10.1002/jemt.20229 | - RUIZ-CHICA, A. JMEDINA, M. A.SANCHEZ-JIMENEZ, F.RAMIREZ, F. J., "Characterization by Raman spectroscopy of conformational changes on guanine- cytosine and adenine-thymine oligonucleotides induced by aminooxy analogues of spermidine", J. Raman Spectrosc., (20040000), vol. 35, pages 93 - 100 | - DUKOR, R. K, "Vibrational spectroscopy in the detection of cancer", Handb. Vib. Spectrosc., (20020000), pages 3335 - 3361 | - DIETER NAUMANN, "Infrared and NIR Raman spectroscopy in medical microbiology", Proc. SPIE 3257, Infrared Spectrosc. New Tool Med., (19980000), vol. 3257, doi:10.1117/12.306089, XP002238946 DOI: http://dx.doi.org/10.1117/12.306089 | - SIGURDSSON, S. et al., "Detection of skin cancer by classification of Raman spectra", IEEE Trans. Biomed. Eng., (20040000), vol. 51, doi:10.1109/TBME.2004.831538, pages 1784 - 1793, XP011119322 DOI: http://dx.doi.org/10.1109/TBME.2004.831538 | - CHAN, J. W. et al., "Micro-Raman spectroscopy detects individual neoplastic and normal hematopoietic cells", Biophys. J, (20060000), vol. 90, pages 648 - 56 | - O FAOLAIN, E. et al., "A study examining the effects of tissue processing on human tissue sections using vibrational spectroscopy", Vib. Spectrosc., (20050000), vol. 38, doi:10.1016/j.vibspec.2005.02.013, pages 121 - 127, XP025324689 DOI: http://dx.doi.org/10.1016/j.vibspec.2005.02.013 | - GNIADECKA, M.WULF, H. C.MORTENSEN, N. N.NIELSEN, O. FCHRISTENSEN, D. H, Diagnosis of basal cell carcinoma by Raman spectroscopy., (19970000), vol. 28, pages 125 - 129 | - J. Raman Spectrosc., (19970000), vol. 28, pages 125 - 129 | - FRANK, C. J.MCCREERY, R. LREDD, D. C, "Raman spectroscopy of normal and diseased human breast tissues", Anal. Chem., (19950000), vol. 67, doi:10.1021/ac00101a001, pages 777 - 83, XP002673806 DOI: http://dx.doi.org/10.1021/ac00101a001 | - JYOTHI LAKSHMI, R. et al., "Tissue Raman spectroscopy for the study of radiation damage: brain irradiation of mice", Radiat Res, (20020000), vol. 157, pages 175 - 182 | - FUNG, M. F. K.SENTERMAN, M. K.MIKHAEL, N. Z.LACELLE, S.WONG, P. T. T, "Pressure-tuning Fourier transform infrared spectroscopic study of carcinogenesis in human endometrium", Biospectroscopy, (19960000), vol. 2, doi:10.1002/(SICI)1520-6343(1996)2:3<155::AID-BSPY2>3.0.CO;2-7, pages 155 - 165, XP000619505 DOI: http://dx.doi.org/10.1002/(SICI)1520-6343(1996)2:3<155::AID-BSPY2>3.0.CO;2-7 |