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Extract from the Register of European Patents

EP About this file: EP0108128

EP0108128 - (Met-1,des-Cys1,des-Tyr2,des-Cys3) human gamma interferon and a DNA sequence encoding it [Right-click to bookmark this link]
Former [1984/20]THE MANUFACTURE AND EXPRESSION OF LARGE STRUCTURAL GENES
[1991/51]
StatusPatent revoked
Status updated on  15.02.2003
Database last updated on 04.12.2024
Most recent event   Tooltip14.05.2014Change: Decision (+date) in appeal procedure 
Applicant(s)For all designated states
Amgen Inc.
One Amgen Center Drive Thousand Oaks
California 91320-1799 / US
[N/P]
Former [2000/51]For all designated states
Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1789 / US
Former [1991/18]For all designated states
AMGEN INC.
1900 Oak Terrace Lane
Thousand Oaks, California 91320 / US
Former [1984/28]For all designated states
Amgen
1900 Oak Terrace Lane
Thousand Oaks California 91320 / US
Former [1984/20]For all designated states
APPLIED MOLECULAR GENETICS INC.
1892 Oak Terrace Lane
Newbury Park, CA 91320 / US
Inventor(s)01 / ALTON, Norman K.
3320 Silver Spur Court
Thousand Oaks, CA 91360 / US
02 / PETERS, Mary A.
945 37th Street
Boulder, CO 80303 / US
03 / STABINSKY, Yitzhak
3415 Heidelberg Drive
Boulder, CO 80303 / US
04 / SNITMAN, David L.
1475 Ithica Drive
Boulder, CO 80303 / US
[1984/20]
Representative(s)Brown, John D., et al
Boehmert & Boehmert
Pettenkoferstrasse 20-22
80336 München / DE
[N/P]
Former [1984/28]Brown, John David, et al
FORRESTER & BOEHMERT Franz-Joseph-Strasse 38
D-80801 München / DE
Former [1984/20]Brown, John David
FORRESTER & BOEHMERT Franz-Joseph-Strasse 38
D-80801 München / DE
Application number, filing date83901979.125.04.1983
[1984/20]
WO1983US00605
Priority number, dateUS1982037549406.05.1982         Original published format: US 375494
US1983048345115.04.1983         Original published format: US 483451
[1984/20]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO8304053
Date:24.11.1983
[1983/27]
Type: A1 Application with search report 
No.:EP0108128
Date:16.05.1984
Language:EN
The application published by WIPO in one of the EPO official languages on 24.11.1983 takes the place of the publication of the European patent application.
[1984/20]
Type: B1 Patent specification 
No.:EP0108128
Date:18.12.1991
Language:EN
[1991/51]
Search report(s)(Supplementary) European search report - dispatched on:EP15.09.1986
ClassificationIPC:C07K13/00, C12N15/23
[1991/51]
CPC:
C12Q1/68 (EP,US); A61P31/12 (EP); A61P37/04 (EP);
A61P43/00 (EP); C07K14/555 (EP,US); C07K14/56 (EP,US);
C07K14/57 (EP,US); C12N15/10 (EP,US); C12N15/70 (EP,US);
C12P21/02 (EP,US); G01N33/534 (EP,US); Y10S435/811 (EP,US);
Y10S930/142 (EP,US) (-)
Former IPC [1984/20]C12P19/34, C12N15/23
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   LI,   LU,   NL,   SE [1984/20]
TitleGerman:(Met-1,des-Cys1,des-Tyr2,des-Cys3) menschliches Gamma-Interferon und dafür kodierende DNS-Sequenz[1991/51]
English:(Met-1,des-Cys1,des-Tyr2,des-Cys3) human gamma interferon and a DNA sequence encoding it[1991/51]
French:(Met-1,des-Cys1,des-Tyr2,des-Cys3) interféron gamma humain et séquence d'ADN qui le code[1991/51]
Former [1984/20]HERSTELLUNG UND EXPRESSION GROSSER STRUKTURELLER GENEN
Former [1984/20]THE MANUFACTURE AND EXPRESSION OF LARGE STRUCTURAL GENES
Former [1984/20]OBTENTION ET EXPRESSION DE GRANDS GENES STRUCTURAUX
MiscellaneousEPB 1991/51: Teilanmeldung 90124234.7 eingereicht am 25/04/83
EPB 1991/51: Divisional application 90124234.7 filed on 25/04/83
EPB 1991/51: Demande divisionnaire 90124234.7 déposée le 25/04/83
Entry into regional phase03.01.1984National basic fee paid 
03.01.1984Search fee paid 
03.01.1984Designation fee(s) paid 
11.04.1984Examination fee paid 
Examination procedure11.04.1984Examination requested  [1984/25]
06.05.1988Despatch of a communication from the examining division (Time limit: M07)
08.12.1988Reply to a communication from the examining division
03.02.1989Despatch of a communication from the examining division (Time limit: M06)
09.08.1989Reply to a communication from the examining division
06.12.1989Despatch of a communication from the examining division (Time limit: M06)
15.06.1990Reply to a communication from the examining division
13.07.1990Despatch of a communication from the examining division (Time limit: M04)
23.11.1990Reply to a communication from the examining division
12.02.1991Despatch of communication of intention to grant (Approval: Yes)
17.06.1991Communication of intention to grant the patent
16.09.1991Fee for grant paid
16.09.1991Fee for publishing/printing paid
Divisional application(s)EP90124234.7  / EP0424990
EP90124236.2  / EP0422697
EP90124237.0  / EP0423845
Opposition(s)Opponent(s)01  20.08.1992  15.10.1992  ADMISSIBLE
Boehringer Ingelheim GmbH
D-55216 Ingelheim / DE
Opponent's representative
Armitage, Ian Michael
Mewburn Ellis LLP
York House
23 Kingsway
London WC2B 6HP / GB
 [N/P]
Former [1994/14]
Opponent(s)01  20.08.1992  15.10.1992  ADMISSIBLE
Boehringer Ingelheim GmbH
D-55216 Ingelheim / DE
Opponent's representative
Armitage, Ian Michael
MEWBURN ELLIS York House 23 Kingsway
London WC2B 6HP / GB
Former [1992/42]
Opponent(s)01  20.08.1992   
Boehringer Ingelheim GmbH
D-55216 Ingelheim / DE
21.10.1992Invitation to proprietor to file observations on the notice of opposition
27.05.1993Reply of patent proprietor to notice(s) of opposition
27.07.1993Despatch of a communication from the opposition division (Time limit: M06)
07.02.1994Reply to a communication from the opposition division
26.06.1995Date of oral proceedings
10.07.1995Despatch of minutes of oral proceedings
20.11.2001Date of oral proceedings
12.12.2001Despatch of minutes of oral proceedings
12.12.2001Despatch of communication that the patent will be revoked
19.12.2002Legal effect of revocation of patent [2003/14]
Appeal following opposition01.09.1995Appeal received No.  T0736/95
20.11.1995Statement of grounds filed
09.10.2000Result of appeal procedure: appeal of the opponent was rejected
13.02.2002Appeal received No.  T0192/02
19.12.2002Result of appeal procedure: appeal of the proprietor inadmissible
09.10.2000Date of oral proceedings
23.10.2000Minutes of the oral proceedings despatched
Fees paidRenewal fee
15.04.1985Renewal fee patent year 03
05.04.1986Renewal fee patent year 04
16.06.1987Renewal fee patent year 05
29.03.1988Renewal fee patent year 06
11.04.1989Renewal fee patent year 07
14.04.1990Renewal fee patent year 08
11.04.1991Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
30.04.198705   M06   Fee paid on   16.06.1987
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:SearchEP0077670  [ ] (GENENTECH INC [US]);
 EP0083777  [ ] (ASAHI CHEMICAL IND [JP]);
 EP0095350  [ ] (SUNTORY LTD [JP]);
 EP0098118  [ ] (LITTON BIONETICS INC [US])
International searchUS4140662  [ ] (RECKEL RUDOLPH P, et al);
 US4225784  [ ] (BARRETT M JAMES);
 US4293652  [ ] (COHEN STANLEY N);
 EP0046039  [ ] (SEARLE & CO [US]);
 US4342832  [ ] (GOEDDEL DAVID V [US], et al);
 US4366246  [ ] (RIGGS ARTHUR D)
 [Y]  - EDGE et al, Nature, Volume 292, 20 August 1981, pages 756-762.
 [Y]  - GRANTHAM et al, Nucleic Acids Research, Volume 8, 1980, pages 1893-1912.
 [X]  - GOEDDEL et al, Nature, Volume 290, 05 March 1981, pages 20-26.
 [YPL]  - FIERS et al, CHEMICAL ABSTRACTS, Volume 98, 1983, Abstract Number 1180u, Philas. Trans. R. Soc. London, Ser. B, 1982, Volume 299, Number 1094, pages 29-38.
 [Y]  - WEENING et al, Biochemical and Biophysical Research Communications, Volume 104, 15 January 1982, pages 6-13.
 [YP]  - GRAY et al, Nature, Volume 298, 26 August 1982, pages 859-863.
 [YP]  - DEVOS et al, Nucleic Acids Research, Volume 10, 1982, pages 2487-2501.
 [Y]  - TANIGUCHI et al, Proc. Natl. Acad. Sci. USA, Volume 78, 1981, pages 3469-3472 .
 [X]  - GRAY et al, Nature, Volume 295, 11 February 1982, pages 503-508.
 [Y]  - GRAY et al, Nature, Volume 295, 11 February 1982, pages 503-508.
 [Y]  - GOLD et al, Ann. Rev. Microbiol., Volume 35, 1981, pages 365-403.
 [XPL]  - GOEDDEL et al, Nature, Volume 290, 05 March 1981, pages 20-26.
 [YPL]  - TANAKA et al, CHEMICAL ABSTRACTS, Volume 98, 1983, Abstract Number 84343Y, Nucleic Acids Symp. Ser., 1982, Volume 11, pages 29-32.
 [YPL]  - TANAKA et al, CHEMICAL ABSTRACTS, Volume 98, 1983: Abstract Number 84343Y, Nucleic Acids Symp. Ser., 1982, Volume 11, pages 29-32.
    [ ] - SIMONSEN et al, CHEMICAL ABSTRACTS, Volume 98, 1983, Abstract Number 1188C, UCLA Symp. Mol. Cell. Biol., 1982, 25 (Interferons), pages 1-14.
Examination   - Nucleic acids research, Symposium series, n°11, November 24, 1982, pages 29-32, IRL Press Ltd, Oxford, GB. S. Tanaka et al "Expression in Escherichia coli of chemically synthesized gene for a human immune interferon"
    - The biology of the interferon system, Proceedings 2nd Int, TNO Meeting, 18-22 April, 1983, pages 119-127, Elsevier Science Publ. B.V. K. Alton et al "Production, characterization and biological effects of recombinant DNA derived human IFN-alpha and IFN-gamma analogs.
    - Nucleic acids research, vol. 11, n° 6, March 25, 1983, pages 1707-1723, IRL Press Ltd, Oxford, GB. S. Tanaka et al "Expression in Escherichia coli of chemically synthesized gene for the human immune interferon"
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.