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Extract from the Register of European Patents

EP About this file: EP0590072

EP0590072 - USE OF SPIN TRAPPING FOR THE TREATMENT OF DISEASES ASSOCIATED WITH OXIDATION OF LIPIDS AND PROTEINS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.10.2002
Database last updated on 23.04.2024
Most recent event   Tooltip06.08.2004Lapse of the patent in a contracting state
New state(s): LU		published on 22.09.2004  [2004/39]
Applicant(s)For all designated states
Oklahoma Medical Research Foundation
825 N.E. 13th Street
Oklahoma City, OK 73104 / US
For all designated states
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
Administration Building, Room 11
Lexington, KY 40506-0032 / US
[N/P]
Former [1994/14]For all designated states
Oklahoma Medical Research Foundation
825 N.E. 13th Street
Oklahoma City Oklahoma 73104 / US
For all designated states
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
Administration Building, Room 11
Lexington, KY 40506-0032 / US
Inventor(s)01 / CARNEY, John, M.
4033 Palomor
Lexington, KY 40503 / US
02 / FLOYD, Robert, A.
12621 Arrowhead Terrace
Oklahoma City, OK 73120 / US
[1994/14]
Representative(s)Burford, Anthony Frederick, et al
Beck Greener
Fulwood House
12 Fulwood Place
London
WC1V 6HR / GB
[N/P]
Former [1994/14]Burford, Anthony Frederick, et al
W.H. Beck, Greener & Co. 7 Stone Buildings Lincoln's Inn
London WC2A 3SZ / GB
Application number, filing date92914539.918.06.1992
[1994/14]
WO1992US05194
Priority number, dateUS1991071695218.06.1991         Original published format: US 716952
[1994/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9222290
Date:23.12.1992
Language:EN
[1992/32]
Type: A1 Application with search report 
No.:EP0590072
Date:06.04.1994
Language:EN
The application published by WIPO in one of the EPO official languages on 23.12.1992 takes the place of the publication of the European patent application.
[1994/14]
Type: B1 Patent specification 
No.:EP0590072
Date:05.12.2001
Language:EN
[2001/49]
Search report(s)International search report - published on:EP23.12.1992
ClassificationIPC:A61K31/135, A61K31/40, A61K31/44, A61K31/445
[1994/14]
CPC:
A61K31/445 (EP); A61K31/135 (EP); A61K31/15 (EP);
A61K31/40 (EP); A61K31/44 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   MC,   NL,   SE [1994/14]
TitleGerman:RADIKALFÄNGER ("SPIN TRAPS") ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN[1994/14]
English:USE OF SPIN TRAPPING FOR THE TREATMENT OF DISEASES ASSOCIATED WITH OXIDATION OF LIPIDS AND PROTEINS[1994/14]
French:EMPLOI DU BLOCAGE PAR SPIN POUR LE TRAITEMENT DE MALADIES ASSOCIEES A L'OXYDATION DES LIPIDES ET DES PROTEINES[1994/14]
Entry into regional phase17.01.1994National basic fee paid 
17.01.1994Designation fee(s) paid 
17.01.1994Examination fee paid 
Examination procedure12.01.1993Request for preliminary examination filed
International Preliminary Examining Authority: EP
17.01.1994Examination requested  [1994/14]
11.01.1996Despatch of a communication from the examining division (Time limit: M06)
21.05.1996Reply to a communication from the examining division
13.11.1996Despatch of a communication from the examining division (Time limit: M04)
16.11.1996Reply to a communication from the examining division
23.06.1997Despatch of a communication from the examining division (Time limit: M04)
28.08.1997Reply to a communication from the examining division
04.06.1999Despatch of communication of intention to grant (Approval: No)
06.12.1999Despatch of communication of intention to grant (Approval: later approval)
31.01.2001Communication of intention to grant the patent
05.05.2001Fee for grant paid
05.05.2001Fee for publishing/printing paid
Opposition(s)06.09.2002No opposition filed within time limit [2002/48]
Fees paidRenewal fee
16.06.1994Renewal fee patent year 03
02.05.1995Renewal fee patent year 04
14.06.1996Renewal fee patent year 05
17.05.1997Renewal fee patent year 06
12.06.1998Renewal fee patent year 07
15.06.1999Renewal fee patent year 08
10.05.2000Renewal fee patent year 09
25.06.2001Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.12.2001
BE05.12.2001
GR05.12.2001
NL05.12.2001
DK05.03.2002
LU18.06.2002
MC18.06.2002
ES27.06.2002
[2004/39]
Former [2004/04]AT05.12.2001
BE05.12.2001
GR05.12.2001
NL05.12.2001
DK05.03.2002
MC18.06.2002
ES27.06.2002
Former [2003/45]AT05.12.2001
BE05.12.2001
GR05.12.2001
NL05.12.2001
DK05.03.2002
MC18.06.2002
Former [2003/25]AT05.12.2001
BE05.12.2001
GR05.12.2001
NL05.12.2001
MC18.06.2002
Former [2003/09]AT05.12.2001
BE05.12.2001
GR05.12.2001
NL05.12.2001
Former [2003/06]BE05.12.2001
GR05.12.2001
NL05.12.2001
Former [2002/49]GR05.12.2001
Cited inInternational search[X]WO8805044  (PHARMACIA AB [SE]);
 [X]WO8805653  (PROCTOR PETER H [US]);
 [X]WO9105552  (OKLAHOMA MED RES FOUND [US], et al)
 [X]  - Proceedings of the National Academy of Sciences of the USA, vol. 88, no. 11, 1 June 1991, D. GELVAN et al.: "Cardiac reperfusion damage prevented by a nitroxide free radical", pages 4680-4684, see whole document
 [X]  - Journal of Cardiovascular Pharmacology, vol. 9, no. 6, June 1987, Raven Press, (New York, US), D.J. HEARSE et al.: "Reperfusion-induced arrhythmias and free radicals: studies in the rat heart with DMPO", pages 641-650, see whole document
 [X]  - Biochimica et Biophysica Acta, vol. 1096, no. 3, 1991, ELsevier Science Publishers B.V., (Amsterdam, NL), R.A. TOWNER et al.: "Enhancement of carbon tetrachloride-induced liver injury by a single dose of ethanol: proton magnetic resonance imaging (MRI) studies in vivo", pages 222-230, see whole document
 [X]  - Journal of Molecular Neuroscience, vol. 3, no. 1, 1991, Birkhäuser, (Boston, US), J.M. CARNEY et al.: "Protection against oxidative damage to CNS by alpha-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: a novel series of nonlipid free radical scavengers", pages 47-57, see whole document
 [A]  - The Journal of Physical Chemistry, vol. 84, no. 5, 6 March 1980, American Chemical Society, E.E. BANCROFT et al.: "Spin trapping with covalently immobilized alpha-phenyl-N-((1-hydroxy-2-methyl)-2-propyl) nitrone", pages 557-558, see whole document
 [X]  - Neuroscience Letters, vol. 116, no. 3, 1990, Elsevier Scientific Publishers Ireland Ltd, J.W. PHILLIS et al.: "Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-alpha-phenylnitrone (PBN)", pages 315-319, see whole document
 [A]  - Izv. Sib. Oto. Akad. Nauk (SSSR), Ser. Klin. Nauk., no. 1, 1989, G.G. DUL'TSEVA et al.: "New spin traps III. 2,3-Dihydropyrazine-1,4-dioxides-cyclic conjugated alpha-dinitrones and alpha-phenylnitrones with functional groups", pages 77-81, see abstract, page 81 and schema 2, page 79
ExaminationUS3834073
 US4153722
 WO9113618
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.