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Extract from the Register of European Patents

EP About this file: EP0859636

EP0859636 - HYALURONIC ACID AS DNA CARRIER FOR GENE THERAPY AND VEGF ANTISENSE DNA TO TREAT ABNORMAL RETINAL VASCULARIZATION [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  13.10.2006
Database last updated on 22.01.2025
Most recent event   Tooltip13.10.2006Withdrawal of applicationpublished on 15.11.2006  [2006/46]
Applicant(s)For all designated states
Hyal Pharmaceutical Australia Limited
Level 4, Suite 3, 51 Rawson Street
Epping N.S.W. 2121 / AU
[1998/35]
Inventor(s)01 / RAKOCZY, Piroska, Elizabeth
Lions Eye Institute 2 Verdun Street
Nedlands, W.A. 6009 / AU
02 / CONSTABLE, Ian, Jeffrey
Lions Eye Institute 2 Verdun Street
Nedlands, W.A. 6009 / AU
[1998/35]
Representative(s)Polz, Leo, et al
Hoffmann - Eitle
ATTENTION : ADDRESS INACTIVE - USE ASS-NR - CDR / DE
[N/P]
Former [2003/37]Polz, Leo, Dr., et al
Hoffmann Eitle Postfach 81 04 20
81904 München / DE
Former [1998/35]Kolb, Helga, Dr. Dipl.-Chem., et al
Hoffmann Eitle, Patent- und Rechtsanwälte, Arabellastrasse 4
81925 München / DE
Application number, filing date96934189.022.10.1996
[1998/35]
WO1996AU00664
Priority number, dateAU1919PN0061623.10.1995         Original published format: AU PN061619
AU1979PN0090401.04.1996         Original published format: AU PN090479
[1998/35]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9715330
Date:01.05.1997
Language:EN
[1997/19]
Type: A1 Application with search report 
No.:EP0859636
Date:26.08.1998
Language:EN
The application published by WIPO in one of the EPO official languages on 01.05.1997 takes the place of the publication of the European patent application.
[1998/35]
Search report(s)International search report - published on:AU01.05.1997
(Supplementary) European search report - dispatched on:EP13.03.2002
ClassificationIPC:C12N15/11, A61K48/00, A61K47/48, C07K14/52, A61K47/36
[2001/46]
CPC:
C12N15/1136 (EP); A61K47/36 (EP,KR); A61K47/61 (EP);
A61K48/00 (EP,KR); A61K9/0014 (EP); A61K9/0019 (EP);
A61P27/00 (EP); A61P27/02 (EP); C07K14/52 (EP);
C12N15/1137 (EP); C12Y304/22027 (EP); C12Y304/23005 (EP);
A61K38/00 (EP); C12N2310/111 (EP); C12N2310/315 (EP);
C12N2799/022 (EP); C12N2799/025 (EP) (-)
Former IPC [1998/35]A61K47/36, A61K48/00
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1998/35]
TitleGerman:HYALURONSÄURE ALS DNA TRÄGER FÜR DIE GENTHERAPIE SOWIE VEGF ANTISENSE-DNA ZUR BEHANDLUNG ABNORMALER NETZHAUTVASKULARISIERUNG[1998/35]
English:HYALURONIC ACID AS DNA CARRIER FOR GENE THERAPY AND VEGF ANTISENSE DNA TO TREAT ABNORMAL RETINAL VASCULARIZATION[1998/35]
French:ACIDE HYALURONIQUE UTILISE COMME PORTEUR D'ADN POUR UNE THERAPIE GENIQUE ET ADN ANTI-SENS DU FACTEUR DE CROISSANCE DE L'ENDOTHELIUM VASCULAIRE POUR LE TRAITEMENT D'UNE VASCULARISATION ANORMALE DE LA RETINE[1998/35]
Entry into regional phase23.04.1998National basic fee paid 
23.04.1998Search fee paid 
23.04.1998Designation fee(s) paid 
23.04.1998Examination fee paid 
Examination procedure01.05.1997Request for preliminary examination filed
International Preliminary Examining Authority: AU
23.04.1998Examination requested  [1998/35]
10.10.2006Application withdrawn by applicant  [2006/46]
Fees paidRenewal fee
12.10.1998Renewal fee patent year 03
14.10.1999Renewal fee patent year 04
11.10.2000Renewal fee patent year 05
11.10.2001Renewal fee patent year 06
19.09.2002Renewal fee patent year 07
14.10.2003Renewal fee patent year 08
14.10.2004Renewal fee patent year 09
12.10.2005Renewal fee patent year 10
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Documents cited:Search[Y]  - SMITH L E H ET AL, "INHIBITION OF PROLIFERATIVE RETINOPATHY USING ANTISENSE PHOSPHOROTHIOATE OLIGONUCLEOTIDES AGAINST VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF/VPF)", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOCIATION FOR RESEARCH IN VISION AND, US, (19950315), vol. 36, no. 4, ISSN 0146-0404, page S871, abstract no. 3992, XP002008713 [Y] 1-31,33-38,40-42,44-47,49-60 * the whole document *
 [YP]  - ROBINSON GREGORY S ET AL, "Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (1996), vol. 93, no. 10, ISSN 0027-8424, pages 4851 - 4856, XP002137716 [YP] 1-31,33-38,40-42,44-47,49-60 * abstract * * page 4853, column R, paragraph RESULTS - page 4854, column R *

DOI:   http://dx.doi.org/10.1073/pnas.93.10.4851
 [Y]  - MUMPER R J ET AL, "NOVEL POLYMERIC CONDENSING CARRIERS FOR GENE DELIVERY", PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, XX, XX, (19950730), vol. 22, ISSN 1022-0178, page 178, XP002048876 [Y] 1-31,33-38,40-42,44-47,49-60 * figures 1,3 *
 [Y]  - MITCHELL SD ET AL, "Antisense RNA to the cell adhesion gene CD44 in melanoma cells (Meeting abstract).", CANCERLIT, NATIONAL CANCER INSTITUTE, BETHESDA, MD, US, Database accession no. 94699907, URL: DIALOG, XP002177966 [Y] 1-31,33-38,40-42,44-47,49-60 * abstract *
    [ ] - J PATHOL; 170, 1993, (SUPPL), ISSN 0022-3417
 [T]  - ELLIS LM ET AL, "Down-regulation of vascular endothelial growth factor in human colon carcinoma cell lines by antisense transfection decreases endothelial cell proliferation.", SURGERY, NOV 1996, VOL. 120, NO. 5, PAGE(S) 871-878, ISSN 0039-6060, XP001027824 [T] 1-31,33-38,40-42,44-47,49-60 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0039-6060(96)80097-3
International search[X]WO9002774  (AUGE PIER SA [FR]);
 [Y]AU6090386  (BIOMATRIX INC);
 [Y]AU5227493  (JAGOTEC AG);
 [XP]WO9623065  (HYBRIDON INC [US], et al);
 [X]WO9504142  (HYBRIDON INC [US], et al);
 [XP]WO9600286  (TOAGOSEI CO LTD [JP], et al);
 [XP]WO9627006  (HYBRIDON INC [US]);
 [Y]WO9213063  (ONCOGENE SCIENCE INC [US])
 [Y]  - CHEMICAL REVIEWS, 1990, Vol. 90, No. 4, UHLMAN and PEYMAN, "Antisense Oligonucleotides", pages 544-579.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.