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Extract from the Register of European Patents

EP About this file: EP0998574

EP0998574 - METHODS OF PERFORMING HOMOLOGOUS RECOMBINATION BASED MODIFICATION OF NUCLEIC ACIDS IN RECOMBINATION DEFICIENT CELLS AND USE OF THE MODIFIED NUCLEIC ACIDS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  31.10.2003
Database last updated on 23.04.2024
Most recent event   Tooltip31.10.2003Application deemed to be withdrawnpublished on 17.12.2003  [2003/51]
Applicant(s)For all designated states
THE ROCKEFELLER UNIVERSITY
1230 York Avenue New York
New York 10021-6399 / US
[N/P]
Former [2000/19]For all designated states
THE ROCKEFELLER UNIVERSITY
1230 York Avenue
New York New York 10021-6399 / US
Inventor(s)01 / HEINTZ, Nathaniel
441 Fowler Avenue
Pelham Manor, NY 10803 / US
02 / MODEL, Peter
500 East 63rd Street
New York, NY 10021 / US
03 / YANG, Xiangdong, W.
1230 York Avenue,Box 339
New York, NY 10021 / US
[2000/19]
Representative(s)HGF
1 City Walk
Leeds LS11 9DX / GB
[N/P]
Former [2000/19]Harrison Goddard Foote
Belmont House, 20 Wood Lane
Leeds LS6 2AE / GB
Application number, filing date98930459.723.06.1998
[2000/19]
WO1998US12966
Priority number, dateUS1997088096623.06.1997         Original published format: US 880966
US1998010249022.06.1998         Original published format: US 102490
[2000/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9859060
Date:30.12.1998
Language:EN
[1998/52]
Type: A1 Application with search report 
No.:EP0998574
Date:10.05.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 30.12.1998 takes the place of the publication of the European patent application.
[2000/19]
Search report(s)International search report - published on:EP30.12.1998
ClassificationIPC:C12N15/70, C12N15/90, A01K67/027
[2000/19]
CPC:
A01K67/0275 (EP); C12N15/70 (EP); C12N15/902 (EP);
A01K2217/05 (EP); C12N2800/202 (EP); C12N2800/204 (EP);
C12N2840/203 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/19]
Extension statesAL24.01.2000
LT24.01.2000
LV24.01.2000
MK24.01.2000
RO24.01.2000
SI24.01.2000
TitleGerman:METHODEN FÜR DIE AUSFÜHRUNG VON HOMOLOGER REKOMBINATION ZUR MODIFIKATION VON NUKLEINSÄUREN IN REKOMBINATIONSDEFIZIENTEN ZELLEN UND DIE VERWENDUNG DER MODIFIZIERTEN NUKLEINSÄUREN[2000/19]
English:METHODS OF PERFORMING HOMOLOGOUS RECOMBINATION BASED MODIFICATION OF NUCLEIC ACIDS IN RECOMBINATION DEFICIENT CELLS AND USE OF THE MODIFIED NUCLEIC ACIDS[2000/19]
French:PROCEDES DE PREFORMAGE DE RECOMBINAISON HOMOLOGUE D'APRES UNE MODIFICATION D'ACIDES NUCLEIQUES DANS DES CELLULES PRESENTANT UNE DEFICIENCE DE RECOMBINAISON, ET UTILISATION DES PRODUITS D'ACIDES NUCLEIQUES MODIFIES DE CELLES-CI[2000/19]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase24.01.2000National basic fee paid 
24.01.2000Designation fee(s) paid 
24.01.2000Examination fee paid 
Examination procedure22.01.1999Request for preliminary examination filed
International Preliminary Examining Authority: US
24.01.2000Examination requested  [2000/19]
04.02.2003Despatch of a communication from the examining division (Time limit: M04)
15.06.2003Application deemed to be withdrawn, date of legal effect  [2003/51]
18.07.2003Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2003/51]
Fees paidRenewal fee
25.05.2000Renewal fee patent year 03
24.05.2001Renewal fee patent year 04
01.07.2002Renewal fee patent year 05
30.06.2003Renewal fee patent year 06
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Cited inInternational search[DA]  - O'CONNOR M. ET AL., "Construction of large DNA segments in Escherichia coli.", SCIENCE, (1989), vol. 244, pages 1307 - 1312, XP002081196 [DA] 1-44 * see the whole document, especially Fig. 1 *

DOI:   http://dx.doi.org/10.1126/science.2660262
 [DA]  - MONACO A. P. ET AL, "YACS, BACS, PACS AND MACS: ARTIFICIAL CHROMOSOMES AS RESEARCH TOOLS", TRENDS IN BIOTECHNOLOGY, (199407), vol. 17, no. 7, pages 280 - 286, XP000601472 [DA] 1-44 * column W *

DOI:   http://dx.doi.org/10.1016/0167-7799(94)90140-6
 [AD]  - KIM U.-J. ET AL., "Construction and characterization of a human bacterial artificial chromosome library.", GENOMICS, (1996), vol. 34, pages 213 - 218, XP002081197 [AD] 1-44 * column W *

DOI:   http://dx.doi.org/10.1006/geno.1996.0268
 [A]  - KÜHN R. ET AL., "Inducible gene targeting in mice.", SCIENCE, (1995), vol. 269, pages 1427 - 1429, XP002081198 [A] 1-44 * column W *

DOI:   http://dx.doi.org/10.1126/science.7660125
 [DA]  - CHATTERJEE P. K. AND COHEN J. S., "Isolating large nested deletions in bacterial and P1 artificial chromosomes by in vivo P1 packaging of products of Cre-catalysed recombination between the endogenous and a transposed loxP site.", NUCLEIC ACIDS RESEARCH, (19970601), vol. 25, no. 11, pages 2205 - 2212, XP002081566 [DA] 1-44 * column W *

DOI:   http://dx.doi.org/10.1093/nar/25.11.2205
 [A]  - LARIONOV V. ET AL., "RECOMBINATION DURING TRANSFORMATION AS A SOURCE OF CHIMERIC MAMMALIAN ARTIFICIAL CHROMOSOMES IN YEAST (YACS)", NUCLEIC ACIDS RESEARCH, (1994), vol. 22, no. 20, pages 4154 - 4161, XP002027292 [A] 1-44 * column W *
 [A]  - EGGLESTON A. K. AND WEST S. C., "Exchanging partners: recombination in E. coli.", TRENDS IN GENETICS, (1996), vol. 12, no. 1, pages 20 - 25, XP002081199 [A] 1-34,40-44 * column W *

DOI:   http://dx.doi.org/10.1016/0168-9525(96)81384-9
 [DA]  - BAKER A. AND COTTEN M., "Delivery of bacterial artificial chromosomes into mammalian cels with psoralen-inactivated adenovirus carrier.", NUCLEIC ACIDS RESEARCH, (19970525), vol. 25, no. 10, pages 1950 - 1956, XP002081200 [DA] 35-39 * column W *

DOI:   http://dx.doi.org/10.1093/nar/25.10.1950
 [PX]  - YANG X. W. ET AL., "Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.", NATURE BIOTECHNOLOGY, (199709), vol. 15, pages 859 - 865, XP002081201 [PX] 1-44 * column W *

DOI:   http://dx.doi.org/10.1038/nbt0997-859
 [T]  - SIMON M. I., "Dysfunctional genomics: BACs to the rescue.", NATURE BIOTECHNOLOGY, (199709), vol. 15, page 839, XP002081202 [T] 1-44 * column W *

DOI:   http://dx.doi.org/10.1038/nbt0997-839
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