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Extract from the Register of European Patents

EP About this file: EP1021429

EP1021429 - ARYL FURAN DERIVATIVES AS PDE IV INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.05.2004
Database last updated on 23.04.2024
Most recent event   Tooltip14.05.2004Application deemed to be withdrawnpublished on 30.06.2004  [2004/27]
14.05.2004Change - representativepublished on 30.06.2004  [2004/27]
Applicant(s)For all designated states
MERCK FROSST CANADA INC.
16711 Trans-Canada Highway Kirkland
Quebec H9H 3L1 / CA
[N/P]
Former [2000/30]For all designated states
MERCK FROSST CANADA INC.
16711 Trans-Canada Highway
Kirkland Quebec H9H 3L1 / CA
Inventor(s)01 / PERRIER, Helene
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
02 / HAN, Yongxin
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
03 / BAYLY, Christopher
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
04 / MacDONALD, Dwight
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
05 / GIROUX, Andre
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
06 / YOUNG, Robert, N.
16711 Trans-Canada Highway
Kirkland, Quebec H9H 3L1 / CA
[2000/30]
Representative(s)Horgan, James Michael Frederic, et al
Merck & Co., Inc.
European Patent Department
Terlings Park
Eastwick Road, Harlow
Essex CM20 2QR / GB
[N/P]
Former [2004/27]Horgan, James Michael Frederic, et al
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Former [2000/30]Thompson, John Dr., et al
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR / GB
Application number, filing date98947246.901.10.1998
[2000/30]
WO1998CA00930
Priority number, dateUS19970061261P03.10.1997         Original published format: US 61261 P
[2000/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9918095
Date:15.04.1999
Language:EN
[1999/15]
Type: A1 Application with search report 
No.:EP1021429
Date:26.07.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 15.04.1999 takes the place of the publication of the European patent application.
[2000/30]
Search report(s)International search report - published on:EP15.04.1999
ClassificationIPC:C07D307/42, A61K31/34, C07D307/38, C07D307/46, C07D307/54, C07D307/56, C07D307/64, C07D307/66, C07D473/38, C07D405/04, C07D405/12, C07D417/12, C07D413/12, C07D405/06, C07F7/08
[2000/30]
CPC:
C07D307/42 (EP,US); A61P11/06 (EP); A61P43/00 (EP);
C07D307/46 (EP,US); C07D307/54 (EP,US); C07D405/04 (EP,US);
C07D405/12 (EP,US); C07D413/12 (EP,US); C07D417/12 (EP,US);
C07F7/0814 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2000/30]
Extension statesAL03.05.2000
LT03.05.2000
LV03.05.2000
MK03.05.2000
RO03.05.2000
SI03.05.2000
TitleGerman:ARYL-FURAN-DERIVATE ALS PDE IV HEMMER[2000/30]
English:ARYL FURAN DERIVATIVES AS PDE IV INHIBITORS[2000/30]
French:DERIVES D'ARYLFURANE UTILISES COMME INHIBITEURS DE PHOSPHODIESTERASE IV (PDE IV)[2000/30]
Entry into regional phase03.05.2000National basic fee paid 
03.05.2000Designation fee(s) paid 
03.05.2000Examination fee paid 
Examination procedure09.04.1999Request for preliminary examination filed
International Preliminary Examining Authority: EP
03.05.2000Examination requested  [2000/30]
14.08.2003Despatch of a communication from the examining division (Time limit: M04)
30.12.2003Application deemed to be withdrawn, date of legal effect  [2004/27]
02.02.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2004/27]
Fees paidRenewal fee
31.10.2000Renewal fee patent year 03
31.10.2001Renewal fee patent year 04
07.10.2002Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.10.200306   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]WO9638412  ;
 [X]JPH0912457  ;
 [X]WO9700068  ;
 [X]JPS59161390  ;
 [X]JPH09194471  ;
 [X]US3531497  (YOUNGDALE GILBERT A) [X] 1,2,5 * the whole document *;
 [X]US3557005  (BROADDUS CHARLES D) [X] 1,2,5,6 * the whole document *;
 [X]US4595693  (BIFTU TESFAYE [US], et al) [X] 1,2,5,6 * column 5 - column 6 *;
 [X]EP0318066  (MERCK & CO INC [US]) [X] 1,2,7-15 * see claims and compound 24 *;
 [X]EP0678296  (TSUMURA & CO [JP]) [X] 1,2,5-8,11-13 * the whole document *;
 [X]  - WATANABE ET AL., "Preparation of lignan compounds as ...", CHEMICAL ABSTRACTS, (19910225), vol. 114, no. 8, Database accession no. 69042, XP002088109 [X] 1,5-15 * abstract *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 97, no. 03, Database accession no. 97-034276, XP002088115 & WO9638412 A 19961205 (TSUMURA & CO) [X] 1,2,5-8,10-15 * abstract *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 97, no. 12, Database accession no. 97-128649, XP002088116 & JPH0912457 A 19970114 (TSUMURA & CO) [X] 1,5-8,10-15 * abstract *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 97, no. 07, Database accession no. 97-077348, XP002088117 & WO9700068 A 19970103 (TSUMURA & CO) [X] 1,2,5,7,8,11-13 * abstract *
 [X]  - GUMP ET AL., "Copper(I)substitutions. Furans from ...", CHEMICAL ABSTRACTS, (19680506), vol. 68, no. 19, Database accession no. 87079, XP002088110 [X] 1,2,5,6 * abstract *
 [X]  - TRAVERSO, "Intermediates necessary in the synthesis...", CHEMICAL ABSTRACTS, (19610306), vol. 55, no. 5, column 4468, XP002088111 [X] 1,2,5,6 * abstract *
 [X]  - KUMAR ET AL., "Synthesis of 3-alkoxy, 3-aryloxy and 3-substituted amino-2,5-diarylfurans ...", CHEMICAL ABSTRACTS, (19950814), vol. 123, no. 7, Database accession no. 83120, XP002088112 [X] 1,2,5,6 * abstract *
 [X]  - IYER ET AL., "Potential antifertility agents...", CHEMICAL ABSTRACTS, (19740610), vol. 80, no. 23, Database accession no. 133166, XP002088113 [X] 1,2,5 * abstract *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 84, no. 43, Database accession no. 84-265910, XP002088118 & JPS59161390 A 19840912 (KURARAY CO LTD) [X] 1,2 * abstract *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 97, no. 40, Database accession no. 97-431452, XP002088119 & JPH09194471 A 19970729 (MITSUBISHI CHEM CORP) [X] 1,2,5 * abstract *
 [X]  - WATANABE ET AL., "An efficient synthesis of 2(5H)-furanone and furan derivatives...", CHEM.PHARM.BULL., (1989), vol. 37, no. 11, pages 2914 - 2919, XP002088108 [X] 1,2,5 * page 2917 *
 [X]  - DAS B P ET AL, "SYNTHESIS AND ANTIPROTOZOAL ACTIVITY OF 2,5-BIS(4-GUANYLPHENYL) FURANS", JOURNAL OF MEDICINAL CHEMISTRY, (197704), vol. 20, no. 4, pages 531 - 536, XP000605199 [X] 1,2,5 * page 532 *

DOI:   http://dx.doi.org/10.1021/jm00214a014
 [X]  - AUTERHOFF ET AL., "Guaiac resins...", CHEMICAL ABSTRACTS, (19661121), vol. 65, no. 11, column 16925, XP002088114 [X] 1,5 * abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.