EP1037587 - SITE-SPECIFIC PREPARATION OF POLYETHYLENE GLYCOL-GRF CONJUGATES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 13.02.2004 Database last updated on 22.02.2019 | Most recent event Tooltip | 13.02.2004 | No opposition filed within time limit | published on 31.03.2004 [2004/14] | Applicant(s) | For all designated states Applied Research Systems ARS Holding N.V. Pietermaai 15 Curaçao / AN | [N/P] |
Former [2003/27] | For all designated states Applied Research Systems ARS Holding N.V. Pietermaai 15 Curacao / AN | ||
Former [2000/39] | For all designated states APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. 14 John B. Gorsiraweg Curaçao / AN | Inventor(s) | 01 /
VERONESE, Francesco, Maria Via Barozzi, 11/B I-35128 Padova / IT | 02 /
CALICETI, Paolo Via Gattamelata, 156/c Int. 1 I-35128 Padova / IT | 03 /
SCHIAVON, Oddone Via Zago, 13 I-35128 Padova / IT | [2000/39] | Representative(s) | Grünecker Patent- und Rechtsanwälte PartG mbB Leopoldstrasse 4 80802 München / DE | [N/P] |
Former [2001/30] | Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät Maximilianstrasse 58 80538 München / DE | ||
Former [2000/39] | Hassa, Jürgen Ares-Serono International S.A., 12, Chemin des Aulx 1228 Plan-les-Ouates / CH | Application number, filing date | 98959898.2 | 01.12.1998 | [2000/39] | WO1998EP07748 | Priority number, date | EP19970121264 | 03.12.1997 Original published format: EP 97121264 | [2000/39] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9927897 | Date: | 10.06.1999 | Language: | EN | [1999/23] | Type: | A1 Application with search report | No.: | EP1037587 | Date: | 27.09.2000 | Language: | EN | The application has been published by WIPO in one of the EPO official languages on 10.06.1999 | [2000/39] | Type: | B1 Patent specification | No.: | EP1037587 | Date: | 09.04.2003 | Language: | EN | [2003/15] | Search report(s) | International search report - published on: | EP | 10.06.1999 | Classification | International: | A61K7/00 | [2000/39] | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2000/39] | Extension states | AL | 07.06.2000 | LT | 07.06.2000 | LV | 07.06.2000 | MK | 07.06.2000 | RO | 07.06.2000 | SI | 07.06.2000 | Title | German: | HERSTELLUNG STELLEN-SPEZIFISCHER POLYETHYLENGLYCOL-GRF KONJUGATE | [2002/48] | English: | SITE-SPECIFIC PREPARATION OF POLYETHYLENE GLYCOL-GRF CONJUGATES | [2000/39] | French: | PREPARATION SPECIFIQUE A UN SITE DE CONJUGUES DE POLYETHYLENE GLYCOL-GRF | [2000/39] |
Former [2000/39] | ORTSPEZIFISCHE VORBEREITUNG VON POLYETHYLENE GLYCOL-GRF KONJUGATEN | Entry into regional phase | 07.06.2000 | National basic fee paid | 07.06.2000 | Designation fee(s) paid | 07.06.2000 | Examination fee paid | Examination procedure | 09.06.1999 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 07.06.2000 | Examination requested [2000/39] | 20.12.2000 | Despatch of a communication from the examining division (Time limit: M06) | 11.06.2001 | Reply to a communication from the examining division | 18.12.2001 | Despatch of communication of intention to grant (Approval: No) | 28.04.2002 | Despatch of communication of intention to grant (Approval: later approval) | 08.07.2002 | Communication of intention to grant the patent | 19.09.2002 | Fee for grant paid | 19.09.2002 | Fee for publishing/printing paid | Opposition(s) | 12.01.2004 | No opposition filed within time limit [2004/14] | Fees paid | Renewal fee | 07.07.2000 | Renewal fee patent year 03 | 13.12.2001 | Renewal fee patent year 04 | 12.12.2002 | Renewal fee patent year 05 | Cited in | International search | [X]EP0400472 (SUMITOMO PHARMA [JP], et al) [X] 1-20 * examples 18,19 *; | [X]EP0473084 (SUMITOMO PHARMA [JP]) [X] 1-20 * example 13; claims 5,8,9,11 *; | [XY]WO9717367 (THERATECHNOLOGIES INC [CA]) [X] 14,15 * page 4, line 28 - page 5, line 10; figure 1 * * tables 2,3 * [Y] 1-13; | [XD]WO9621469 (SHEARWATER POLYMERS INC [US], et al) [XD] 1-20 * abstract * * page 66 *; | [X]EP0518295 (MILLIPORE CORP [US]) [X] 14,15 * abstract * | [YD] - CAMPBELL RM ET AL, "Pegylated peptides. V. Carboxy-terminal PEGylated analogs of growth hormone-releasing factor (GRF) display enhanced duration of biological activity in vivo.", J PEPT RES, JUN 1997, 49 (6) P527-37, DENMARK, XP000657594 [YD] 1-20 * page 527, column 2 * * figure 2 * DOI: http://dx.doi.org/10.1111/j.1399-3011.1997.tb01160.x | [XD] - FELIX AM ET AL, "Pegylated peptides. IV. Enhanced biological activity of site-directed pegylated GRF analogs.", INT J PEPT PROTEIN RES, SEP-OCT 1995, 46 (3-4) P253-64, DENMARK, XP002064559 [XD] 1-20 * page 261 - page 263; figure 3; table 1 * DOI: http://dx.doi.org/10.1111/j.1399-3011.1995.tb00597.x | [Y] - ZALIPSKY S, "CHEMISTRY OF POLYETHYLENE GLYCOL CONJUGATES WITH BIOLOGICALLY ACTIVE MOLECULES", ADVANCED DRUG DELIVERY REVIEWS, (1995), vol. 16, no. 2/03, pages 157 - 182, XP002037428 [Y] 1-20 * page 159 - page 161; figures 1,2 * * page 166, column 2 - page 168, column 1 * DOI: http://dx.doi.org/10.1016/0169-409X(95)00023-Z | [A] - ZHANG C. ET AL, "Radioimmunoassay of growth hormone-releasing hormone (GHRH) with a polyclonal antibody against synthetic GHRH(1-29)-Gly4-Cys-NH2: Method and clinical studies", CLIN. CHIM. ACTA, 1991, 202/3 (243-254), NETHERLANDS, XP002064562 [A] 1-13 * abstract * * page 245, paragraph 1 * DOI: http://dx.doi.org/10.1016/0009-8981(91)90055-H | [Y] - GAERTNER H F ET AL, "SITE-SPECIFIC ATTACHMENT OF FUNCTIONALIZED POLY(ETHYLENE GLYCOL) TOTHE AMINO TERMINUS OF PROTEINS", BIOCONJUGATE CHEMISTRY, (1996), vol. 7, no. 1, pages 38 - 44, XP000646874 [Y] 1-15 * abstract * DOI: http://dx.doi.org/10.1021/bc950074d | [Y] - FRANCIS G E ET AL, "POLYETHYLENE GLYCOL MODIFICATION: RELEVANCE OF IMPROVED METHODOLOGY TO TUMOUR TARGETING", JOURNAL OF DRUG TARGETING, (1996), vol. 3, pages 321 - 340, XP002058312 [Y] 1-20 * abstract * | [X] - FISCHER D ET AL, "PEG-PROTEIN CONSTRUCTS FOR CLINICAL USE", PERSPECTIVE PROTEIN ENG. COMPLEMENTARY TECHNOLOGY COLLECT PAPERS INTERNATIONAL SYMPOSIUM, (1995), pages 223 - 226, XP002060507 [X] 16-20 * the whole document * |