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Extract from the Register of European Patents

EP About this file: EP1144435

EP1144435 - PYROGLUTAMIC ACID DERIVATIVES AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.02.2007
Database last updated on 17.07.2024
Most recent event   Tooltip07.08.2009Lapse of the patent in a contracting state
New state(s): CY		published on 09.09.2009  [2009/37]
Applicant(s)For all designated states
ELAN PHARMACEUTICALS, INC.
800 Gateway Boulevard
South San Francisco, CA 94080 / US
For all designated states
Wyeth
Five Giralda Farms
Madison, NJ 07940-0874 / US
[N/P]
Former [2006/15]For all designated states
ELAN PHARMACEUTICALS, INC.
800 Gateway Boulevard
South San Francisco, CA 94080 / US
For all designated states
Wyeth
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Former [2002/49]For all designated states
Elan Pharmaceuticals, Inc.
800 Gateway Boulevard
South San Francisco, CA 94080 / US
For all designated states
Wyeth
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Former [2001/42]For all designated states
Elan Pharmaceuticals, Inc.
800 Gateway Boulevard
South San Francisco, CA 94080 / US
For all designated states
AMERICAN HOME PRODUCTS CORPORATION
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Inventor(s)01 / DRESSEN, Darren, B.
3110 Casa De Campo, 2
San Mateo, CA 94403 / US
02 / KREFT, Anthony
43 Barley Court
Langhorne, PA 19047 / US
03 / KUBRAK, Dennis
3231 Gaul Street
Philidelphia, PA 19128 / US
04 / MANN, Charles, William
122 South Fifth Street
North Wales, PA 19454 / US
05 / PLEISS, Michael, A.
848 Stella Court
Sunnyvale, CA 94086 / US
06 / STACK, Gary, Paul
525 Brookfield Lane
Ambler, PA 19002 / US
07 / THORSETT, Eugene, D.
571 Buena Vista
Moss Beach, CA 94038 / US
 [2001/42]
Representative(s)Roques, Sarah Elizabeth, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2004/11]Roques, Sarah Elizabeth, et al
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Former [2001/42]Senior, Janet, et al
Abel & Imray 20 Red Lion Street
London WC1R 4PQ / GB
Application number, filing date00904486.821.01.2000
[2001/42]
WO2000US01537
Priority number, dateUS1999023866126.01.1999         Original published format: US 238661
[2001/42]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0043413
Date:27.07.2000
Language:EN
[2000/30]
Type: A2 Application without search report 
No.:EP1144435
Date:17.10.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 27.07.2000 takes the place of the publication of the European patent application.
[2001/42]
Type: B1 Patent specification 
No.:EP1144435
Date:12.04.2006
Language:EN
[2006/15]
Search report(s)International search report - published on:EP30.11.2000
ClassificationIPC:C07K5/00
[2001/42]
CPC:
C07K5/06173 (EP); A61P1/04 (EP); A61P11/06 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P17/06 (EP);
A61P25/28 (EP); A61P27/00 (EP); A61P29/00 (EP);
A61P3/10 (EP); A61P35/04 (EP); A61P9/10 (EP);
C07K5/06139 (EP); C07K5/06165 (EP); C07K5/06191 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/42]
Extension statesAL26.07.2001
LT26.07.2001
LV26.07.2001
MK26.07.2001
RO26.07.2001
SI26.07.2001
TitleGerman:PYROGLUTAMINSÄUREDERIVATE UND DAMIT VERWANDTE VERBINDUNGEN, DIE DIE DURCH VLA-4 VERMITTELTE LEUKOZYTENADHÄSION VERRINGERN[2001/42]
English:PYROGLUTAMIC ACID DERIVATIVES AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4[2001/42]
French:DERIVES D'ACIDE PYROGLUTAMIQUE ET COMPOSES ASSOCIES, INHIBITEURS DE L'ADHESION LEUKOCYTAIRE A MEDIATION DE VLA-4[2001/42]
MiscellaneousEPB 2001/42: Derzeit sind die WIPO-Publikationsdaten A3 nicht verfügbar.
EPB 2001/42: WIPO A3 publication data is not currently available.
EPB 2001/42: L'OMPI données de publication A3 ne sont pas actuellement disponibles.
Entry into regional phase26.07.2001National basic fee paid 
26.07.2001Designation fee(s) paid 
26.07.2001Examination fee paid 
Examination procedure10.08.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
26.07.2001Examination requested  [2001/42]
13.08.2003Despatch of a communication from the examining division (Time limit: M06)
23.02.2004Reply to a communication from the examining division
24.05.2004Despatch of a communication from the examining division (Time limit: M04)
29.09.2004Reply to a communication from the examining division
06.05.2005Communication of intention to grant the patent
21.10.2005Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
07.11.2005Fee for grant paid
07.11.2005Fee for publishing/printing paid
Divisional application(s)EP05019666.6  / EP1612215
Opposition(s)15.01.2007No opposition filed within time limit [2007/12]
Request for further processing for:07.11.2005Request for further processing filed
07.11.2005Full payment received (date of receipt of payment)
Request granted
21.11.2005Decision despatched
Fees paidRenewal fee
28.01.2002Renewal fee patent year 03
28.01.2003Renewal fee patent year 04
14.01.2004Renewal fee patent year 05
19.01.2005Renewal fee patent year 06
19.01.2006Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT12.04.2006
BE12.04.2006
CH12.04.2006
CY12.04.2006
FI12.04.2006
LI12.04.2006
NL12.04.2006
DK12.07.2006
SE12.07.2006
GR13.07.2006
PT12.09.2006
[2009/37]
Former [2008/19]AT12.04.2006
BE12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
NL12.04.2006
DK12.07.2006
SE12.07.2006
GR13.07.2006
PT12.09.2006
Former [2008/04]AT12.04.2006
BE12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
NL12.04.2006
DK12.07.2006
SE12.07.2006
PT12.09.2006
Former [2007/35]AT12.04.2006
BE12.04.2006
CH12.04.2006
FI12.04.2006
IT12.04.2006
LI12.04.2006
NL12.04.2006
DK12.07.2006
SE12.07.2006
PT12.09.2006
Former [2007/19]AT12.04.2006
BE12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
NL12.04.2006
DK12.07.2006
SE12.07.2006
PT12.09.2006
Former [2007/13]AT12.04.2006
BE12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
DK12.07.2006
SE12.07.2006
PT12.09.2006
Former [2007/09]AT12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
DK12.07.2006
SE12.07.2006
PT12.09.2006
Former [2007/08]AT12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
DK12.07.2006
SE12.07.2006
Former [2007/03]AT12.04.2006
CH12.04.2006
FI12.04.2006
LI12.04.2006
SE12.07.2006
Former [2006/52]AT12.04.2006
FI12.04.2006
SE12.07.2006
Former [2006/51]FI12.04.2006
SE12.07.2006
Former [2006/48]SE12.07.2006
Cited inInternational search[A]WO9601644  (ATHENA NEUROSCIENCES INC [US], et al) [A] 1,16,28-30 * example -; claim - *;
 [X]WO9748726  (TAKEDA CHEMICAL INDUSTRIES LTD [JP], et al) [X] 1-9,12 * page 30, line 35 *;
 [PA]WO9906432  (ATHENA NEUROSCIENCES INC [US], et al) [PA] 1,16,28-30 * example -; claim - *;
 [PX]WO9967230  (UPJOHN CO [US], et al) [PX] 1-30 * example -; claim - *;
 [X]  - PAPAIOANNOU, DIONISSIOS ET AL, "Facile preparation of the 1-hydroxybenzotriazolyl ester of N-tritylpyroglutamic acid and its application to the synthesis of TRH, [D-His2]TRH and analogs incorporating cis- and trans-4-hydroxy-L-proline", ACTA CHEM. SCAND. (1995), 49(2), 103-14, (199502), XP002141997 [X] 1-9,12 * compound 15a;; figure 1 *
 [X]  - KATO, YOJI ET AL, "Oxidative degradation of collagen and its model peptide by ultraviolet irradiation", J. AGRIC. FOOD CHEM. (1992), 40(3), 373-9, (1992), XP002141998 [X] 1-9,12 * figure 7 *

DOI:   http://dx.doi.org/10.1021/jf00015a003
 [X]  - EWENSON, A. ET AL, "Analogs of substance P containing an.alpha.-hydroxy,.beta.-amino acid: synthesis and biological activity", EUR. J. MED. CHEM. (1991), 26(4), 435-42, (1991), XP002141999 [X] 1-9,12 * scheme 3; page 441, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/0223-5234(91)90104-U
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.