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Extract from the Register of European Patents

EP About this file: EP1159063

EP1159063 - METHOD FOR SYNTHESIZING, PURIFYING AND CHARACTERIZING COMBINATORIAL LIBRARIES [Right-click to bookmark this link]
Former [2001/49]METHOD AND APPARATUS FOR SYNTHESIZING, PURIFYING AND CHARACTERIZING COMBINATORIAL LIBRARIES
[2005/03]
StatusNo opposition filed within time limit
Status updated on  30.06.2006
Database last updated on 12.07.2024
Most recent event   Tooltip05.12.2008Lapse of the patent in a contracting state
New state(s): CY
published on 07.01.2009  [2009/02]
Applicant(s)For all designated states
Scynexis, Inc.
3501-C Tricenter Boulevard
Durham, NC 27713 / US
[2004/23]
Former [2004/06]For all designated states
Scynexis Chemistry and Automation, Inc.
3501-C Tricenter Boulevard
Durham, NC 27713 / US
Former [2001/49]For all designated states
AVENTIS CROPSCIENCE S.A.
55, avenue René Cassin
69009 Lyon / FR
Inventor(s)01 / RIBEILL, Yves
313 Meetinghouse Circle
Raleigh, NC 27609 / US
02 / MONNET, Pierre
601 Jones Ferry Road
Carroboro, NC 27510 / US
03 / ABEDI, Jaleh, Azmi
2601 Sunnystone Way
Raleigh, NC 26713 / US
04 / SMITH, Henry, David, III
220 Dutchess Drive
Cary, NC 27513 / US
05 / MCCOMB, Susan, Marie
110 Arrowhead Way
Cary, NC 27513 / US
 [2001/49]
Representative(s)Andersson, Per Rune
Zacco Sweden AB
P.O. Box 5581
114 85 Stockholm / SE
[N/P]
Former [2001/49]Andersson, Per Rune
Albihns Göteborg AB Box 142
401 22 Göteborg / SE
Application number, filing date00907620.911.02.2000
[2001/49]
WO2000EP01525
Priority number, dateUS19990119619P11.02.1999         Original published format: US 119619 P
US1999024854111.02.1999         Original published format: US 248541
US19990156375P28.09.1999         Original published format: US 156375 P
US19990157191P30.09.1999         Original published format: US 157191 P
US19990157475P01.10.1999         Original published format: US 157475 P
[2001/49]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0047540
Date:17.08.2000
Language:EN
[2000/33]
Type: A2 Application without search report 
No.:EP1159063
Date:05.12.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 17.08.2000 takes the place of the publication of the European patent application.
[2001/49]
Type: B1 Patent specification 
No.:EP1159063
Date:24.08.2005
Language:EN
[2005/34]
Search report(s)International search report - published on:EP12.04.2001
ClassificationIPC:B01J19/00, B01L3/00, B01L9/06
[2001/49]
CPC:
B01J19/0046 (EP); B01J2219/00283 (EP); B01J2219/00308 (EP);
B01J2219/00452 (EP); B01J2219/0054 (EP); B01J2219/00585 (EP);
B01J2219/00599 (EP); B01J2219/00689 (EP); B01J2219/00691 (EP);
B01J2219/00693 (EP); B01J2219/00698 (EP); B01J2219/00704 (EP);
B01J2219/00707 (EP); B01J2219/0072 (EP); B01J2219/00722 (EP);
B01J2219/00725 (EP); B01J2219/00745 (EP); B01J2219/00754 (EP);
C40B40/10 (EP); C40B40/14 (EP); C40B40/18 (EP);
C40B50/08 (EP); C40B70/00 (EP); G01N2035/00217 (EP);
G01N35/028 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/49]
TitleGerman:VERFAHREN ZUR SYNTHESE, REINIGUNG UND CHARAKTERISIERUNG VON KOMBINATORISCHEN BIBLIOTHEKEN[2005/03]
English:METHOD FOR SYNTHESIZING, PURIFYING AND CHARACTERIZING COMBINATORIAL LIBRARIES[2005/03]
French:PROCEDE DE SYNTHESE, DE CARACTERISATION, ET DE CRIBLAGE DE BANQUES COMBINATOIRES[2005/03]
Former [2001/49]VERFAHREN UND VORRICHTUNG ZUR SYNTHESE, REINIGUNG UND CHARAKTERISIERUNG VON KOMBINATORISCHEN BIBLIOTHEKEN
Former [2001/49]METHOD AND APPARATUS FOR SYNTHESIZING, PURIFYING AND CHARACTERIZING COMBINATORIAL LIBRARIES
Former [2001/49]PROCEDE ET APPAREIL DE SYNTHESE, DE CARACTERISATION, ET DE CRIBLAGE DE BANQUES COMBINATOIRES
Entry into regional phase07.09.2001National basic fee paid 
07.09.2001Designation fee(s) paid 
07.09.2001Examination fee paid 
Examination procedure04.09.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
07.09.2001Examination requested  [2001/49]
12.09.2001Amendment by applicant (claims and/or description)
06.02.2003Despatch of a communication from the examining division (Time limit: M04)
07.03.2003Reply to a communication from the examining division
24.04.2003Despatch of a communication from the examining division (Time limit: M04)
21.08.2003Reply to a communication from the examining division
15.02.2005Communication of intention to grant the patent
20.06.2005Fee for grant paid
20.06.2005Fee for publishing/printing paid
Opposition(s)26.05.2006No opposition filed within time limit [2006/31]
Fees paidRenewal fee
13.02.2002Renewal fee patent year 03
12.02.2003Renewal fee patent year 04
12.02.2004Renewal fee patent year 05
14.02.2005Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT24.08.2005
BE24.08.2005
CY24.08.2005
FI24.08.2005
IT24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
IE13.02.2006
LU28.02.2006
MC28.02.2006
[2009/02]
Former [2007/35]AT24.08.2005
BE24.08.2005
FI24.08.2005
IT24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
IE13.02.2006
LU28.02.2006
MC28.02.2006
Former [2007/12]AT24.08.2005
BE24.08.2005
FI24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
IE13.02.2006
LU28.02.2006
MC28.02.2006
Former [2007/08]AT24.08.2005
BE24.08.2005
FI24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
LU28.02.2006
MC28.02.2006
Former [2006/44]AT24.08.2005
BE24.08.2005
FI24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
MC28.02.2006
Former [2006/26]AT24.08.2005
BE24.08.2005
FI24.08.2005
NL24.08.2005
DK24.11.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
Former [2006/25]AT24.08.2005
BE24.08.2005
FI24.08.2005
NL24.08.2005
GR24.11.2005
ES05.12.2005
PT24.01.2006
Former [2006/14]AT24.08.2005
FI24.08.2005
NL24.08.2005
GR24.11.2005
ES05.12.2005
Former [2006/13]AT24.08.2005
FI24.08.2005
Cited inInternational search[A]WO9709353  (PATHOGENESIS CORP [US], et al) [A] 43-46* page 7, line 12 - page 9, line 25; figures 1A,1B *;
 [X]WO9710896  (BERLEX LAB [US], et al) [X] 21 * page 11, line 6 - line 9; figures 1,13-15 * * page 15, line 8 - line 15 *;
 [X]WO9745443  (ALANEX CORP [US]) [X] 37-46 * page 8, line 21 - page 9, line 20; figures 1,2C,2D,4A-C,5-8 * * page 6, line 30 - line 33 * * page 12, line 23 - line 25 * * page 10, line 24 - page 11, line 6 * * page 11, line 16 - page 12, line 10 *;
 [X]WO9815825  (IRORI [US]) [X] 21,22,32,33,36 * page 92, line 8 - page 94, line 32; figures 61-67 *;
 [XA]WO9822219  (ROBBINS SCIENT CORP [US]) [X] 21,22,27-30,36 * page 23, line 12 - page 25, line 3 * * page 25, line 5 - line 22; figures 8,12,13 * * page 15, line 9 - line 18 * * page 18, line 19 - line 28 * [A] 23-26,31-35;
 [XA]EP0882500  (SUMITOMO CHEMICAL CO [JP]) [X] 11-13 * abstract * * column 25, line 27 - line 42 * * column 27, line 3 - line 13 * * column 9, line 21 - column 10, line 56 * [A] 1-8,14-20;
 [XA]  - SCHULTZ L ET AL, "High throughput purification of combinatorial libraries", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,GB,OXFORD, (19980908), vol. 8, no. 17, ISSN 0960-894X, pages 2409 - 2414, XP004138241 [X] 1-5,11-15,17,19,20 * the whole document * [A] 18

DOI:   http://dx.doi.org/10.1016/S0960-894X(98)00436-3
 [X]  - DEWITT S H ET AL, "COMBINATORIAL ORGANIC SYNTHESIS USING PARKE-DAVIS'S DIVERSOMER METHOD", ACCOUNTS OF CHEMICAL RESEARCH,US,AMERICAN CHEMICAL SOCIETY. WASHINGTON, (19960101), vol. 29, no. 3, ISSN 0001-4842, pages 114 - 122, XP002065653 [X] 11,12 * page 116 - page 118, column 1; figures 1,2 * * page 120 - page 122, column 1 *

DOI:   http://dx.doi.org/10.1021/ar950209v
 [XA]  - RUDGE D A, "The automation of solution phase synthetic chemistry using XP Zymate@? laboratory robotic systems", LABORATORY AUTOMATION & INFORMATION MANAGEMENT,NL,ELSEVIER SCIENCE PUBLISHERS BV., AMSTERDAM, (19971201), vol. 33, no. 2, ISSN 1381-141X, pages 81 - 86, XP004108755 [X] 11-13 * the whole document * [A] 1-6,14-20

DOI:   http://dx.doi.org/10.1016/S1381-141X(97)00010-5
 [X]  - ZENG L ET AL, "Automated analytical/preparative high-performance liquid chromatography-mass spectrometry system for the rapid characterization and purification of compound libraries", JOURNAL OF CHROMATOGRAPHY A,NL,ELSEVIER SCIENCE, (19980123), vol. 794, no. 1-2, ISSN 0021-9673, pages 3 - 13, XP004115380 [X] 14,17-20 * scheme 1, page 6 *

DOI:   http://dx.doi.org/10.1016/S0021-9673(97)01008-X
 [XA]  - GRIFFEY R H ET AL, "Rapid Deconvolution of Combinatorial Libraries using HPLC Fractionation", TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, (19980416), vol. 54, no. 16, ISSN 0040-4020, pages 4067 - 4076, XP004162180 [X] 14,15,17,18,20 * abstract * * page 4068 - page 4069 * [A] 1-13

DOI:   http://dx.doi.org/10.1016/S0040-4020(98)00135-5
 [XA]  - LINDSEY J S, "A RETROSPECTIVE ON THE AUTOMATION OF LABORATORY SYNTHETIC CHEMISTRY", LABORATORY AUTOMATION & INFORMATION MANAGEMENT,NL,ELSEVIER SCIENCE PUBLISHERS BV., AMSTERDAM, (19921001), vol. 17, no. 1, ISSN 1381-141X, pages 15 - 45, XP000321829 [X] 14,15,18 * page 30; figure 11 * * page 27 - page 34 * [A] 1-13
 [A]  - KIBBEY, C.E., "An automated system for the purification of combinatorial libraries by preperative LC/MS", LABORATORY ROBOTICS AND AUTOMATION, (1997), vol. 9, pages 309 - 321, XP000913652 [A] 1,14 * abstract * * page 313, column 2 - page 314, column 1 *

DOI:   http://dx.doi.org/10.1002/(SICI)1098-2728(1997)9:6<309::AID-LRA5>3.0.CO;2-4
 [A]  - JOSSES; METIVIER ET AL., "Carrying out multiple reactions in organic synthesis with a robot", ADVANCES IN LABORATORY AUTOMATION ROBOTICS, (1990), vol. 6, pages 463 - 475, XP000913653 [A] 1-13 * abstract * * page 474, paragraph 2; figures 1-6 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.