blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1150666

EP1150666 - GM-CSF FOR THE TREATMENT OF CROHN'S DISEASE [Right-click to bookmark this link]
Former [2001/45]STIMULATING NEUTROPHIL FUNCTION TO TREAT INFLAMMATORY BOWEL DISEASE
[2009/19]
StatusNo opposition filed within time limit
Status updated on  03.09.2010
Database last updated on 24.08.2024
Most recent event   Tooltip28.09.2012Lapse of the patent in a contracting state
New state(s): NL		published on 31.10.2012  [2012/44]
Applicant(s)For all designated states
Washington University
School of Medicine, 724 South Euclid Avenue, P.O. Box 8013
St. Louis, MO 63110 / US
[2009/44]
Former [2001/45]For all designated states
WASHINGTON UNIVERSITY
School of Medicine, 724 South Euclid Avenue, P.O. Box 8013
St. Louis, MO 63110 / US
Inventor(s)01 / DIECKGRAEFE, Brian
14301 Bramblewood Court
Chesterfield, MO 63017 / US
02 / KORZENICK, Joshua
Apartment 3E, 4927 Laclede Avenue
St. Louis, MO 63108 / US
 [2001/45]
Representative(s)Tombling, Adrian George, et al
Withers & Rogers LLP
2 London Bridge
London SE1 9RA / GB
[N/P]
Former [2001/45]Tombling, Adrian George, et al
Withers & Rogers Goldings House 2 Hays Lane
London SE1 2HW / GB
Application number, filing date00913421.411.02.2000
[2001/45]
WO2000US03407
Priority number, dateUS19990119842P12.02.1999         Original published format: US 119842 P
[2001/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0047195
Date:17.08.2000
Language:EN
[2000/33]
Type: A1 Application with search report 
No.:EP1150666
Date:07.11.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 17.08.2000 takes the place of the publication of the European patent application.
[2001/45]
Type: B1 Patent specification 
No.:EP1150666
Date:28.10.2009
Language:EN
[2009/44]
Search report(s)International search report - published on:US17.08.2000
(Supplementary) European search report - dispatched on:EP20.05.2003
ClassificationIPC:A61K38/19, A61P1/00, A61P1/04
[2009/19]
CPC:
A61K45/06 (EP); A61K31/00 (EP); A61K38/193 (EP);
A61P1/00 (EP); A61P1/04 (EP); A61P1/16 (EP);
A61P17/00 (EP); A61P17/02 (EP); A61P27/02 (EP);
A61P29/00 (EP); A61P31/04 (EP); A61P37/06 (EP);
A61P37/08 (EP); A61P43/00 (EP) (-)
Former IPC [2003/26]A61K45/00, A61K38/19, A61P1/00, A61P1/04
Former IPC [2001/45]A61K31/00, A61K31/16
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2009/44]
Former [2001/45]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
Extension statesAL24.08.2001
LT24.08.2001
LV24.08.2001
MK24.08.2001
RO24.08.2001
SI24.08.2001
TitleGerman:GM-CSF ZUR BEHANDLUNG VON MORBUS CROHN[2009/19]
English:GM-CSF FOR THE TREATMENT OF CROHN'S DISEASE[2009/19]
French:GM-CSF POUR LE TRAITEMENT DE LA MALADIE DE CROHN[2009/19]
Former [2001/45]STIMULIERUNG DER NEUTROPHIL-FUNKTION ZUR BEHANDLUNG VON ENTZÜNDLICHEN DARMERKRANKUNGEN
Former [2001/45]STIMULATING NEUTROPHIL FUNCTION TO TREAT INFLAMMATORY BOWEL DISEASE
Former [2001/45]STIMULATION DE LA FONCTION NEUROPHILE POUR TRAITER LES TROUBLES INTESTINAUX INFLAMMATOIRES
Entry into regional phase24.08.2001National basic fee paid 
24.08.2001Search fee paid 
24.08.2001Designation fee(s) paid 
24.08.2001Examination fee paid 
Examination procedure07.09.2000Request for preliminary examination filed
International Preliminary Examining Authority: US
24.08.2001Examination requested  [2001/45]
10.07.2003Amendment by applicant (claims and/or description)
23.09.2003Despatch of a communication from the examining division (Time limit: M04)
01.12.2003Reply to a communication from the examining division
19.05.2004Despatch of a communication from the examining division (Time limit: M06)
18.11.2004Reply to a communication from the examining division
10.04.2006Despatch of a communication from the examining division (Time limit: M06)
19.10.2006Reply to a communication from the examining division
22.01.2008Despatch of a communication from the examining division (Time limit: M04)
10.03.2008Reply to a communication from the examining division
11.04.2008Despatch of a communication from the examining division (Time limit: M04)
30.04.2008Reply to a communication from the examining division
14.05.2009Communication of intention to grant the patent
15.09.2009Fee for grant paid
15.09.2009Fee for publishing/printing paid
Opposition(s)29.07.2010No opposition filed within time limit [2010/40]
Fees paidRenewal fee
22.02.2002Renewal fee patent year 03
12.02.2003Renewal fee patent year 04
12.02.2004Renewal fee patent year 05
28.02.2005Renewal fee patent year 06
14.02.2006Renewal fee patent year 07
14.02.2007Renewal fee patent year 08
13.02.2008Renewal fee patent year 09
13.02.2009Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
IT28.10.2009
NL28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
IE11.02.2010
LU11.02.2010
CH28.02.2010
LI28.02.2010
MC01.03.2010
PT01.03.2010
[2012/44]
Former [2012/43]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
IT28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
IE11.02.2010
LU11.02.2010
CH28.02.2010
LI28.02.2010
MC01.03.2010
PT01.03.2010
Former [2011/14]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
IT28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
IE11.02.2010
CH28.02.2010
LI28.02.2010
MC01.03.2010
PT01.03.2010
Former [2011/07]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
IE11.02.2010
CH28.02.2010
LI28.02.2010
MC01.03.2010
PT01.03.2010
Former [2010/47]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
CH28.02.2010
LI28.02.2010
MC01.03.2010
PT01.03.2010
Former [2010/46]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
SE28.10.2009
GR29.01.2010
ES08.02.2010
MC01.03.2010
PT01.03.2010
Former [2010/35]AT28.10.2009
BE28.10.2009
CY28.10.2009
DK28.10.2009
FI28.10.2009
SE28.10.2009
ES08.02.2010
PT01.03.2010
Former [2010/29]AT28.10.2009
BE28.10.2009
CY28.10.2009
FI28.10.2009
SE28.10.2009
ES08.02.2010
PT01.03.2010
Former [2010/25]CY28.10.2009
FI28.10.2009
SE28.10.2009
ES08.02.2010
PT01.03.2010
Former [2010/22]FI28.10.2009
SE28.10.2009
ES08.02.2010
PT01.03.2010
Former [2010/19]ES08.02.2010
Documents cited:Search[Y]US5733915  (SANDBORN WILLIAM J [US]) [Y] 26,27 *claims*; column 1, line 10 - line 29 *;
 [PX]WO0006080  (DOECKE WOLF DIETRICH [DE], et al) [PX] 1,3,5,30* page 2, line 10 - page 3, line 13; examples 1,2 *;
 [XY]  - VAUGHAN D ET AL, "Treatment of fistulas with granulocyte colony-stimulating factor in a patient with Crohn's disease.", THE NEW ENGLAND JOURNAL OF MEDICINE. UNITED STATES 21 JAN 1999, (19990121), vol. 340, no. 3, ISSN 0028-4793, pages 239 - 240, XP009010167 [X] 1,3,5,7,9,11-25,28-30,32,33 * the whole document * [Y] 26,27

DOI:   http://dx.doi.org/10.1056/NEJM199901213400317
 [Y]  - EGAN L J ET AL, "A randomized, single-blind, pharmacokinetic and dose response study of subcutaneous methotrexate, 15 and 25 mg/week, for refractory ulcerative colitis and Crohn's disease.", GASTROENTEROLOGY, Digestive Diseases Week and the 99th Annual Meeting of the American Gastroenterological Association;New Orleans, Louisiana, USA; May 16-22, 1998, (19980415), vol. 114, no. 4 PART 2, ISSN 0016-5085, pages A970 - A971, XP009010308 [Y] 26,27 * abstract *

DOI:   http://dx.doi.org/10.1016/S0016-5085(98)83952-8
International search[A]US4961926  (GABRILOVE JANICE L [US]);
 [A]US5654186  (CERAMI ANTHONY [US], et al);
 [A]US5767156  (FERRANTE ANTONIO [AU], et al);
 [AP]US6037324  (SCHWENDER CHARLES F [US], et al)
Examination   - ROE ET AL., "Brief report: Treatment of chronic inflammatory bowel disease in glycogen storage disease type Ib with colony stimulating factor.", THE NEW ENGLAND JOURNAL OF MEDICINE, (19920618), vol. 326, no. 25, pages 1666 - 1669
by applicant   - VAUGHAN ET AL., THE NEW ENGLAND JOURNAL OF MEDICINE, (1999), vol. 340, pages 239 - 240
    - ROE ET AL., THE NEW ENGLAND JOURNAL OF MEDICINE, (1992), vol. 326, pages 1666 - 1669
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.