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Extract from the Register of European Patents

EP About this file: EP1213026

EP1213026 - BRAIN CELL OR NERVE CELL PROTECTING AGENTS COMPRISING GINSENG [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 18.01.2008 Database last updated on 13.07.2024
Most recent event Tooltip	18.01.2008	Application deemed to be withdrawn	published on 20.02.2008 [2008/08]
Applicant(s)	For all designated states Japan Science and Technology Agency 4-1-8, Honcho Kawaguchi-shi Saitama / JP
	[N/P]
Former [2004/21]	For all designated states Japan Science and Technology Agency 4-1-8-, Honcho Kawaguchi-shi Saitama / JP
Former [2002/24]	For all designated states Japan Science and Technology Corporation 1-8, Hon-cho 4-chome Kawaguchi-shi, Saitama 332-0012 / JP
Inventor(s)	01 / SAKANAKA, Masahiro 1191-13, Oaza Shitsukawa, Shigenobu-cho Onsen-gun, Ehime 791-0204 / JP
	02 / MAEDA, Nobuji Ko 911-69, 5-chome, Higashino Matsuyama-shi, Ehime 790-0903 / JP
	03 / TANAKA, Junya 355-31, Oaza Yokogawara, Shigenobu-cho Onsen-gun, Ehime 791-0203 / JP
	04 / NAKATA, Kimihiko 853, Shimoagawa Iyo-shi, Ehime 799-3111 / JP
	[2002/24]
Representative(s)	Cresswell, Thomas Anthony, et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ / GB
	[N/P]
Former [2002/24]	Cresswell, Thomas Anthony, et al J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5JJ / GB
Application number, filing date	00939126.9	22.06.2000
	[2002/24]
	WO2000JP04102
Priority number, date	JP19990243378	30.08.1999 Original published format: JP 24337899
	[2002/24]
Filing language	JA
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO0115717
	Date:	08.03.2001
	Language:	EN
	[2001/10]
	Type:	A1 Application with search report
	No.:	EP1213026
	Date:	12.06.2002
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 08.03.2001 takes the place of the publication of the European patent application.
	[2002/24]
Search report(s)	International search report - published on:	JP	08.03.2001
	(Supplementary) European search report - dispatched on:	EP	04.05.2004
Classification	IPC:	A61K35/78, A61K31/704, C07J17/00, A61P9/08, A61P25/00, A61P43/00, G01N33/15, G01N33/50	[2002/24]
	CPC:	A61K31/00 (EP,US); A61K36/258 (EP,KR,US); A61K31/704 (EP,US); A61P25/00 (EP); A61P43/00 (EP); A61P9/08 (EP); (+) A61P9/10 (EP); C07J17/00 (EP,US) (-)
Designated contracting states	CH, DE, FR, GB, LI, NL, SE [2004/21]
Former [2002/24]	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE
Title	German:	GEHIRN- ODER NERVENZELLEN SCHÜTZENDE WIRKSTOFFE DIE GINSENG ENTHALTEN	[2002/24]
	English:	BRAIN CELL OR NERVE CELL PROTECTING AGENTS COMPRISING GINSENG	[2002/24]
	French:	AGENTS CONTENANT DU GINSENG DESTINES A PROTEGER LES CELLULES CEREBRALES OU LES CELLULES NERVEUSES	[2002/24]
Entry into regional phase	26.03.2002	Translation filed
	26.03.2002	National basic fee paid
	26.03.2002	Search fee paid
	26.03.2002	Designation fee(s) paid
	26.03.2002	Examination fee paid
Examination procedure	13.11.2000	Request for preliminary examination filed International Preliminary Examining Authority: JP
	26.03.2002	Amendment by applicant (claims and/or description)
	26.03.2002	Examination requested [2002/24]
	24.06.2005	Despatch of a communication from the examining division (Time limit: M06)
	04.01.2006	Reply to a communication from the examining division
	12.04.2007	Despatch of a communication from the examining division (Time limit: M04)
	23.08.2007	Application deemed to be withdrawn, date of legal effect [2008/08]
	26.09.2007	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2008/08]
Fees paid	Renewal fee
	24.04.2002	Renewal fee patent year 03
	12.06.2003	Renewal fee patent year 04
	14.06.2004	Renewal fee patent year 05
	14.06.2005	Renewal fee patent year 06
	14.06.2006	Renewal fee patent year 07
	Penalty fee
	Additional fee for renewal fee
	30.06.2007	08 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]JPH02152926 ;
		[X]CN1102099 ;
		[X]US4966893 (PANG PETER K T [CA], et al) [X] 1-14,18-24 * column 5, line 34 - column 6, line 33; claims 1-3 *;
		[X]WO9909837 (CV TECHNOLOGIES INC [CA], et al) [X] 1-14,18-24 * page 15, line 15 - page 16, line 9 *;
		[PX]WO0004912 (MOOK INHEE [KR], et al) [PX] 1-14,18-24 * page 17; claims 1-3 *;
		[E]EP1170012 (JAPAN SCIENCE & TECH CORP [JP]) [E] 1-25,34-37,39-43 * page 15, line 32 - line 52 *;
		[X] - WEN T-C ET AL, "GINSENG ROOT PREVENTS LEARNING DISABILITY AND NEURONAL LOSS IN GERBILS WITH 5-MINUTE FOREBRAIN ISCHEMIA", ACTA NEUROPATHOLOGICA, SPRINGER VERLAG, BERLIN, DE, (1996), vol. 91, no. 1, ISSN 0001-6322, pages 15 - 22, XP001059706 [X] 1-14,18-24 * page 16, column 2; figure 2 * DOI: http://dx.doi.org/10.1007/s004010050387
		[X] - KIM YOUNG C ET AL, "Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (19980815), Database accession no. PREV199800408338, XP002268122 [X] 1-14,18-24 * abstract *
		[ ] - JOURNAL OF NEUROSCIENCE RESEARCH, (19980815), vol. 53, no. 4, ISSN 0360-4012, pages 426 - 432
		[PX] - LIN, MEI-CHIH ET AL, "Transformation of ginsenosides Rg1 and Rb1, and crude Sanchi saponins by human intestinal microflora", CHEMABS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2001:204459, URL: STN, XP002276421 [PX] 26-32,38 * abstract *
		[X] - YHANG Y G ET AL, "INFLUENCES OF GINSENOSIDES RB1 AND RG1 ON REVERSIBLE FOCAL BRAIN ISCHEMIA IN RATS", ZHONGUA YAOLI XUEBAO - ACTA PHARMACOLOGICA SINICA, SHANGHAI, CN, (199601), vol. 17, no. 1, ISSN 0253-9756, pages 44 - 48, XP002926090 [X] 1-24,34-37,39-43 * page 45, column 1 - page 46, column 1 * * page 47, column 1 *
		[X] - SAKANAKA M ET AL, "GINSENG ROOT'S ABILITY TO PREVENT LEARNING DISABILITY AND NEURONAL LOSS IN NORMOTHERMIC GERBILS WITH 5-MIN FOREBRAIN ISCHEMIA", JAPANESE JOURNAL OF PHARMACOLOGY, THE JAPANESE PHARMACOLOGICAL SOCIETY, KYOTO, JP, (19950325), vol. 67, no. SUPPL 1, ISSN 0021-5198, page 297P, XP001059689 [X] 1-24,34-37,39-43 * abstract *
		[X] - GONG X ET AL, "Stroke therapy in traditional Chinese medicine (TCM): prospects for drug discovery and development", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, (19990501), vol. 20, no. 5, ISSN 0165-6147, pages 191 - 196, XP004170241 [X] 1-12,14-17,34-37,39-43 * page 195; figure 1 * DOI: http://dx.doi.org/10.1016/S0165-6147(98)01276-0
		[X] - PATENT ABSTRACTS OF JAPAN, (19900831), vol. 014, no. 403, Database accession no. (C - 0753), & JP02152926 A 19900612 (TSUMURA & CO) [X] 1-12,14-17,37,41 * abstract *
		[X] - DATABASE WPI, 0, Derwent World Patents Index, vol. 1997, no. 25, Database accession no. 1997-272832, XP002276423 & CN1102099 A 19950503 (XIE G) [X] 1-12,14-17,37,41 * abstract *
		[XY] - CHOI DONG-HEE ET AL, "Inhibitory effects of Panax ginseng saponin fractions on dexamethasone-induced thymus apoptosis", SYMPOSIUM ON CURRENT TOPICS IN PHARMACOLOGY AND TOXICOLOGY CATHOLIC RESEARCH INSTITUTES OF MEDICAL SCIENCE {A}, THE CATHOLIC UNIVERSITY OF KOREA, SEOUL, SOUTH KOREA, & MEETING; SEOUL, SOUTH KOREA; OCTOBER 13-14, 1997, (1997), page 162, XP001180904 [X] 1-12,14-17,37,41 [Y] 25
		[X] - KIM YOUNG-RAN ET AL, "Panax ginseng blocks morphine-induced thymic apoptosis by lowering plasma corticosterone level", GENERAL PHARMACOLOGY, &, (199906), vol. 32, no. 6, ISSN 0306-3623, pages 647 - 652, XP002276420 [X] 1-12,14-17,37,41 * page 649, column 2 * DOI: http://dx.doi.org/10.1016/S0306-3623(98)00240-7
		[X] - CHEN X, "CARDIOVASCULAR PROTECTION BY GINSENOSIDES AND THEIR NITRIC OXIDE RELEASING ACTION", CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, XX, XX, (1996), vol. 23, pages 728 - 732, XP000917542 [X] 1-12,14 * page 729, column 1 *
		[A] - GONZALEZ-GARCIA M ET AL, "Bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (199505), vol. 92, no. 10, ISSN 0027-8424, pages 4304 - 4308, XP002251602 [A] 1-43 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.92.10.4304
	International search	[X]WO9008315 (PANG PETER K T [CA], et al);
		[X]JPH06316527 (MORI TETSUO, et al);
		[XP]JP2000159793 (TAISHO PHARMA CO LTD, et al);
		[X] - J.Q. LI ET AL., "Study on the anti-apoptptic mecvhanism of ginsenoside Rg1 in cultured cortical neurons", ACTA PHARMACEUTICA SINICA, (1997), vol. 32, no. 6, pages 406 - 410, XP002933191
		[X] - SUNG-HO KIM ET AL., "Radioprotectiv effect of red ginseng in irradiated mice with high and low dose of radiation", KOREAN J. GINSENG SCI., (1998), vol. 22, no. 1, pages 66 - 72, XP002933192
		[X] - ZHANG YING-GE ET AL., "Influences of ginsenosides Rb1 and Rg1 on reversible focal brain ischemia in rats", ACTA PHARM. SINICA, (1996), vol. 17, no. 1, pages 44 - 48, XP002933193
		[X] - NEUROSCIENCE RESEARCH, (1997), vol. 28, pages 191 - 200, XP002933194 DOI: http://dx.doi.org/10.1016/S0168-0102(97)00041-2
		[X] - ACTA PHARMACEUTICA SINICA, (1995), vol. 30, no. 9, XP002933195
		[X] - ZHANG YING-GE ET AL., "Protective effects of total saponins of panax ginseng on ischemia-reperfusion injury in rat brains", ZHONGGUO YAOLIXUE YU DULIXUE ZAZHI, (1994), vol. 8, no. 1, pages 7 - 12, XP002933196
		[X] - CHU GUOXIANG ET AL., "Protective effect of ginsenoside on acute cerebral ischemia/reperfusion injury of rats", ZHONGGUO YAOLIXUE YU DULIXUE ZAZHI, (1989), vol. 3, no. 1, pages 18 - 21, XP002933197
		[X] - JIANG YAN ET AL., "Influences of ginsenosides Rb1, Rb2 and Rb3 on electric and contractile activities of normal and damaged cultured myocardiocytes", ACTA PHARMACOLOGICA SINICA, (1992), vol. 13, no. 5, pages 403 - 406, XP002933198
		[X] - FANG YUN-XIANG ET AL., "Benefical changes in prostacyclin and thromboxane A2 by ginsenosides in myocardial infarction and reperfusion injury of dogs", ACTA PHARMACOLOGICA SINICA, (1986), vol. 7, no. 3, pages 222 - 226, XP002933199
		[X] - XIU CHEN, "cardiovascular protection by ginsenosides and their nitric oxide releasing action", CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, (1996), vol. 23, no. 8, pages 728 - 732, XP002933200
		[X] - LI YUAN-JIAN, "The protective effect of ginsenosides and its components onmyocytes anoxia/reoxygenation and myocardial reperfusion injury", ACTA PHARMACEUTICA SINICA, (1987), vol. 22, no. 1, pages 1 - 5, XP002933316
		[A] - MATAO KANAOKA ET AL., "Studieson the enzyme immunoassay of bio-active constituents in oriental medicinal drugs. VI. Enzyme immunoassay of ginsenoside Rb1 from panax ginseng", CHEM. PHARM. BULL., (1992), vol. 40, no. 2, pages 314 - 317, XP002933317
		[Y] - NORIKO KONDO ET AL., "Studies on the constituents of himalayan ginseng, panax pseudoginseng. I. The structure of the saponins", CHEM. PHARM. BULL., (1973), vol. 21, no. 13, pages 2702 - 2711, XP002933318

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