EP1212621 - SCREENING FOR AGENTS MODULATING TGF-BETA CELL SIGNALLING [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.05.2008 Database last updated on 24.08.2024 | Most recent event Tooltip | 18.02.2011 | Lapse of the patent in a contracting state New state(s): IT | published on 23.03.2011 [2011/12] | Applicant(s) | For all designated states SIGNAL PHARMACEUTICALS, INC. 5555 Oberlin Drive San Diego, CA 92121 / US | [2002/24] | Inventor(s) | 01 /
HOEKSTRA, Merl, F. 2361 Manchester Avenue Cardiff-by-the-sea, CA 92007 / US | 02 /
XIE, Weilin 5375 Ruette de Mer San Diego, CA 92130 / US | 03 /
MURRAY, Brion, W. 2685 Narcissus Drive San Diego, CA 92106 / US | 04 /
MERCURIO, Frank, M. 2707 Caminito Verdugo Del Mar, CA 92014 / US | [2002/24] | Representative(s) | Killin, Stephen James, et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD / GB | [N/P] |
Former [2002/24] | Killin, Stephen James, et al Venner, Shipley & Co., 20 Little Britain London EC1A 7DH / GB | Application number, filing date | 00959571.1 | 29.08.2000 | [2002/24] | WO2000US23729 | Priority number, date | US19990385918 | 30.08.1999 Original published format: US 385918 | [2002/24] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO0116604 | Date: | 08.03.2001 | Language: | EN | [2001/10] | Type: | A1 Application with search report | No.: | EP1212621 | Date: | 12.06.2002 | Language: | EN | The application published by WIPO in one of the EPO official languages on 08.03.2001 takes the place of the publication of the European patent application. | [2002/24] | Type: | B1 Patent specification | No.: | EP1212621 | Date: | 25.07.2007 | Language: | EN | [2007/30] | Search report(s) | International search report - published on: | EP | 08.03.2001 | Classification | IPC: | G01N33/68, C12Q1/25, G01N33/50, G01N33/566 | [2002/24] | CPC: |
G01N33/74 (EP,US);
A61P29/00 (EP);
A61P35/00 (EP);
A61P43/00 (EP);
C12Q1/25 (EP,US);
G01N2333/495 (EP,US);
G01N2500/10 (EP,US)
(-)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2002/24] | Extension states | AL | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | RO | Not yet paid | SI | Not yet paid | Title | German: | SCREENING NACH VERBINDUNGEN, DIE TGF-BETA ABHÄNGIGE ZELLSIGNALE MODIFIZIEREN KÖNNEN | [2002/24] | English: | SCREENING FOR AGENTS MODULATING TGF-BETA CELL SIGNALLING | [2002/24] | French: | CRIBLAGE D'AGENTS MODULATEURS DE SIGNALISATION CELLULAIRE TGF-BETA | [2002/24] | Entry into regional phase | 26.03.2002 | National basic fee paid | 26.03.2002 | Designation fee(s) paid | 26.03.2002 | Examination fee paid | Examination procedure | 26.03.2001 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 26.03.2002 | Examination requested [2002/24] | 06.06.2002 | Amendment by applicant (claims and/or description) | 30.10.2003 | Despatch of a communication from the examining division (Time limit: M06) | 19.03.2004 | Reply to a communication from the examining division | 08.04.2004 | Despatch of a communication from the examining division (Time limit: M06) | 18.10.2004 | Reply to a communication from the examining division | 14.09.2006 | Cancellation of oral proceeding that was planned for 20.09.2006 | 14.09.2006 | Minutes of oral proceedings despatched | 20.09.2006 | Date of oral proceedings (cancelled) | 16.01.2007 | Communication of intention to grant the patent | 22.05.2007 | Fee for grant paid | 22.05.2007 | Fee for publishing/printing paid | Divisional application(s) | EP07010063.1 / EP1918716 | Opposition(s) | 28.04.2008 | No opposition filed within time limit [2008/27] | Fees paid | Renewal fee | 30.08.2002 | Renewal fee patent year 03 | 28.08.2003 | Renewal fee patent year 04 | 26.08.2004 | Renewal fee patent year 05 | 26.08.2005 | Renewal fee patent year 06 | 14.08.2006 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AT | 25.07.2007 | BE | 25.07.2007 | CY | 25.07.2007 | DK | 25.07.2007 | FI | 25.07.2007 | NL | 25.07.2007 | IE | 29.08.2007 | LU | 29.08.2007 | IT | 31.08.2007 | MC | 31.08.2007 | SE | 25.10.2007 | GR | 26.10.2007 | ES | 05.11.2007 | PT | 26.12.2007 | [2011/12] |
Former [2009/37] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
CY | 25.07.2007 | ||
DK | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
IE | 29.08.2007 | ||
LU | 29.08.2007 | ||
MC | 31.08.2007 | ||
SE | 25.10.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2009/33] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
CY | 25.07.2007 | ||
DK | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
IE | 29.08.2007 | ||
MC | 31.08.2007 | ||
SE | 25.10.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/45] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
DK | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
IE | 29.08.2007 | ||
MC | 31.08.2007 | ||
SE | 25.10.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/28] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
DK | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
MC | 31.08.2007 | ||
SE | 25.10.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/23] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
DK | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
MC | 31.08.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/19] | AT | 25.07.2007 | |
BE | 25.07.2007 | ||
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
GR | 26.10.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/13] | AT | 25.07.2007 | |
FI | 25.07.2007 | ||
NL | 25.07.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/10] | FI | 25.07.2007 | |
NL | 25.07.2007 | ||
ES | 05.11.2007 | ||
PT | 26.12.2007 | ||
Former [2008/09] | NL | 25.07.2007 | |
ES | 05.11.2007 | ||
Former [2008/08] | ES | 05.11.2007 | Cited in | International search | [A]WO9901765 (SLOAN KETTERING INST CANCER [US]) [A] 1-54 * the whole document *; | [X] - ZHU HAITAO ET AL, "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.", NATURE (LONDON), (19990812), vol. 400, no. 6745, ISSN 0028-0836, pages 687 - 693, XP000960653 [X] 1-15 * page 688, column R, paragraph 2 * * page 688, column R, paragraph 5 * DOI: http://dx.doi.org/10.1038/23293 | [A] - MIYAZONO K, "Signal transduction by bone morphogenetic protein receptors: Functional roles of Smad proteins.", BONE (NEW YORK), Second Joint Meeting of the American Society for Bone and Mineral Research and the International Bone and Mineral Society;San Francisco, California, USA; December 1-6, 1998, (199907), vol. 25, no. 1, ISSN 8756-3282, pages 91 - 93, XP000964877 [A] 1-54 * the whole document * DOI: http://dx.doi.org/10.1016/S8756-3282(99)00113-1 | [A] - HELDIN ET AL, "TGF-beta signalling from cell membrane to nucleus through SMAD proteins", NATURE,MACMILLAN JOURNALS LTD. LONDON,GB, (19971204), vol. 390, ISSN 0028-0836, pages 465 - 471, XP002110963 [A] 1-54 * the whole document * DOI: http://dx.doi.org/10.1038/37284 |