blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1212621

EP1212621 - SCREENING FOR AGENTS MODULATING TGF-BETA CELL SIGNALLING [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.05.2008
Database last updated on 24.08.2024
Most recent event   Tooltip18.02.2011Lapse of the patent in a contracting state
New state(s): IT
published on 23.03.2011  [2011/12]
Applicant(s)For all designated states
SIGNAL PHARMACEUTICALS, INC.
5555 Oberlin Drive
San Diego, CA 92121 / US
[2002/24]
Inventor(s)01 / HOEKSTRA, Merl, F.
2361 Manchester Avenue
Cardiff-by-the-sea, CA 92007 / US
02 / XIE, Weilin
5375 Ruette de Mer
San Diego, CA 92130 / US
03 / MURRAY, Brion, W.
2685 Narcissus Drive
San Diego, CA 92106 / US
04 / MERCURIO, Frank, M.
2707 Caminito Verdugo
Del Mar, CA 92014 / US
 [2002/24]
Representative(s)Killin, Stephen James, et al
Venner Shipley LLP
200 Aldersgate
London EC1A 4HD / GB
[N/P]
Former [2002/24]Killin, Stephen James, et al
Venner, Shipley & Co., 20 Little Britain
London EC1A 7DH / GB
Application number, filing date00959571.129.08.2000
[2002/24]
WO2000US23729
Priority number, dateUS1999038591830.08.1999         Original published format: US 385918
[2002/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0116604
Date:08.03.2001
Language:EN
[2001/10]
Type: A1 Application with search report 
No.:EP1212621
Date:12.06.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 08.03.2001 takes the place of the publication of the European patent application.
[2002/24]
Type: B1 Patent specification 
No.:EP1212621
Date:25.07.2007
Language:EN
[2007/30]
Search report(s)International search report - published on:EP08.03.2001
ClassificationIPC:G01N33/68, C12Q1/25, G01N33/50, G01N33/566
[2002/24]
CPC:
G01N33/74 (EP,US); A61P29/00 (EP); A61P35/00 (EP);
A61P43/00 (EP); C12Q1/25 (EP,US); G01N2333/495 (EP,US);
G01N2500/10 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/24]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:SCREENING NACH VERBINDUNGEN, DIE TGF-BETA ABHÄNGIGE ZELLSIGNALE MODIFIZIEREN KÖNNEN[2002/24]
English:SCREENING FOR AGENTS MODULATING TGF-BETA CELL SIGNALLING[2002/24]
French:CRIBLAGE D'AGENTS MODULATEURS DE SIGNALISATION CELLULAIRE TGF-BETA[2002/24]
Entry into regional phase26.03.2002National basic fee paid 
26.03.2002Designation fee(s) paid 
26.03.2002Examination fee paid 
Examination procedure26.03.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
26.03.2002Examination requested  [2002/24]
06.06.2002Amendment by applicant (claims and/or description)
30.10.2003Despatch of a communication from the examining division (Time limit: M06)
19.03.2004Reply to a communication from the examining division
08.04.2004Despatch of a communication from the examining division (Time limit: M06)
18.10.2004Reply to a communication from the examining division
14.09.2006Cancellation of oral proceeding that was planned for 20.09.2006
14.09.2006Minutes of oral proceedings despatched
20.09.2006Date of oral proceedings (cancelled)
16.01.2007Communication of intention to grant the patent
22.05.2007Fee for grant paid
22.05.2007Fee for publishing/printing paid
Divisional application(s)EP07010063.1  / EP1918716
Opposition(s)28.04.2008No opposition filed within time limit [2008/27]
Fees paidRenewal fee
30.08.2002Renewal fee patent year 03
28.08.2003Renewal fee patent year 04
26.08.2004Renewal fee patent year 05
26.08.2005Renewal fee patent year 06
14.08.2006Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT25.07.2007
BE25.07.2007
CY25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
IE29.08.2007
LU29.08.2007
IT31.08.2007
MC31.08.2007
SE25.10.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
[2011/12]
Former [2009/37]AT25.07.2007
BE25.07.2007
CY25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
IE29.08.2007
LU29.08.2007
MC31.08.2007
SE25.10.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2009/33]AT25.07.2007
BE25.07.2007
CY25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
IE29.08.2007
MC31.08.2007
SE25.10.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2008/45]AT25.07.2007
BE25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
IE29.08.2007
MC31.08.2007
SE25.10.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2008/28]AT25.07.2007
BE25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
MC31.08.2007
SE25.10.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2008/23]AT25.07.2007
BE25.07.2007
DK25.07.2007
FI25.07.2007
NL25.07.2007
MC31.08.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2008/19]AT25.07.2007
BE25.07.2007
FI25.07.2007
NL25.07.2007
GR26.10.2007
ES05.11.2007
PT26.12.2007
Former [2008/13]AT25.07.2007
FI25.07.2007
NL25.07.2007
ES05.11.2007
PT26.12.2007
Former [2008/10]FI25.07.2007
NL25.07.2007
ES05.11.2007
PT26.12.2007
Former [2008/09]NL25.07.2007
ES05.11.2007
Former [2008/08]ES05.11.2007
Cited inInternational search[A]WO9901765  (SLOAN KETTERING INST CANCER [US]) [A] 1-54 * the whole document *;
 [X]  - ZHU HAITAO ET AL, "A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.", NATURE (LONDON), (19990812), vol. 400, no. 6745, ISSN 0028-0836, pages 687 - 693, XP000960653 [X] 1-15 * page 688, column R, paragraph 2 * * page 688, column R, paragraph 5 *

DOI:   http://dx.doi.org/10.1038/23293
 [A]  - MIYAZONO K, "Signal transduction by bone morphogenetic protein receptors: Functional roles of Smad proteins.", BONE (NEW YORK), Second Joint Meeting of the American Society for Bone and Mineral Research and the International Bone and Mineral Society;San Francisco, California, USA; December 1-6, 1998, (199907), vol. 25, no. 1, ISSN 8756-3282, pages 91 - 93, XP000964877 [A] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.1016/S8756-3282(99)00113-1
 [A]  - HELDIN ET AL, "TGF-beta signalling from cell membrane to nucleus through SMAD proteins", NATURE,MACMILLAN JOURNALS LTD. LONDON,GB, (19971204), vol. 390, ISSN 0028-0836, pages 465 - 471, XP002110963 [A] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.1038/37284
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.