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Extract from the Register of European Patents

EP About this file: EP1232278

EP1232278 - MICROBIAL 9$g(a)-HYDROXYLATION OF STEROIDS [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  14.11.2008
Database last updated on 24.08.2024
Most recent event   Tooltip14.11.2008Change - refusalpublished on 17.12.2008  [2008/51]
Applicant(s)For all designated states
N.V. Organon
Kloosterstraat 6
5349 AB Oss / NL
[2006/41]
Former [2002/34]For all designated states
Akzo Nobel N.V.
Velperweg 76
6824 BM Arnhem / NL
Inventor(s)01 / VAN DER GEIZE, Robert
Zaagmuldersweg 586
NL-9713 LZ Groningen / NL
02 / HESSELS, Gerda
Kraaienest 131
NL-9733 HK Groningen / NL
03 / DIJKHUIZEN, Lubbert
Ter Borch 28
NL-9474 RB Zuidlaren / NL
 [2002/34]
Representative(s)Kraak, Hajo, et al
N.V. Organon
Global Patent Department
P.O. Box 20
5340 BH Oss / NL
[N/P]
Former [2006/41]Kraak, Hajo, et al
N.V. Organon Global Patent Department P.O. Box 20
5340 BH Oss / NL
Former [2002/34]Hogenbirk, Marijke
P.O. Box 20
5340 BH Oss / NL
Application number, filing date00977417.517.10.2000
[2002/34]
WO2000EP10223
Priority number, dateEP1999020347022.10.1999         Original published format: EP 99203470
EP1999020444922.12.1999         Original published format: EP 99204449
[2002/34]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0131050
Date:03.05.2001
Language:EN
[2001/18]
Type: A1 Application with search report 
No.:EP1232278
Date:21.08.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 03.05.2001 takes the place of the publication of the European patent application.
[2002/34]
Search report(s)International search report - published on:EP03.05.2001
ClassificationIPC:C12P33/00, C12N9/02, C12N15/53, C12N15/63, C12N15/01, C12N1/21, C12N15/76
[2002/34]
CPC:
C12N9/001 (EP); C12N1/205 (EP); C12P33/06 (EP);
C12R2001/01 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/34]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:9ALPHA-HYDROXYLIERUNG VON STEROIDEN IN MIKROORGANISMEN[2002/34]
English:MICROBIAL 9$g(a)-HYDROXYLATION OF STEROIDS[2002/34]
French:9$G(a)-HYDROXYLATION MICROBIENNE DE STEROIDES[2002/34]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase22.05.2002National basic fee paid 
22.05.2002Designation fee(s) paid 
22.05.2002Examination fee paid 
Examination procedure11.05.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
22.05.2002Examination requested  [2002/34]
10.03.2005Despatch of a communication from the examining division (Time limit: M06)
06.09.2005Reply to a communication from the examining division
10.02.2006Despatch of a communication from the examining division (Time limit: M06)
22.09.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
30.11.2006Reply to a communication from the examining division
15.11.2007Cancellation of oral proceeding that was planned for 19.11.2007
15.11.2007Minutes of oral proceedings despatched
19.11.2007Date of oral proceedings (cancelled)
22.11.2007Despatch of communication that the application is refused, reason: substantive examination [2008/50]
22.11.2007Despatch of communication that the application is refused, reason: substantive examination [2008/51]
02.12.2007Application refused, date of legal effect [2008/50]
02.12.2007Application refused, date of legal effect [2008/51]
Appeal following examination17.01.2008Appeal received No.  T0965/08
20.03.2008Statement of grounds filed
08.09.2008Result of appeal procedure: the application was withdrawn
Request for further processing for:30.11.2006Request for further processing filed
30.11.2006Full payment received (date of receipt of payment)
Request granted
13.12.2006Decision despatched
Fees paidRenewal fee
31.10.2002Renewal fee patent year 03
31.10.2003Renewal fee patent year 04
02.11.2004Renewal fee patent year 05
31.10.2005Renewal fee patent year 06
31.10.2006Renewal fee patent year 07
31.10.2007Renewal fee patent year 08
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Cited inInternational search[X]US5004695  (JEKKEL NEE BOKANY ANTONIA [HU], et al) [X] 1,2,10,13 * column 2, line 1 - line 38 * * column 5, line 1 - line 36 *;
 [A]  - JOHNSTON D M ET AL, "Construction of mutant strains of Neisseria gonorrhoeae lacking new antibiotic resistance markers using a two gene cassette with positive and negative selection", GENE, (19990805), vol. 236, no. 1, ISSN 0378-1119, pages 179 - 184, XP004175461 [A] 5,7,8 * page 181, column 1, line 34 - column 2, line 14 *

DOI:   http://dx.doi.org/10.1016/S0378-1119(99)00238-3
 [A]  - MORII S. ET AL., "3-Ketosteroid-delta1-dehydrogenase of Rhodococcus rhodochrous:sequencing of the genomic DNA and hyperexpression, purification, and characterization of the recombinant enzyme", JOURNAL OF BIOCHEMISTRY, (199811), vol. 124, no. 5, pages 1026 - 1032, XP000891250 [A] 1-15 * the whole document *
 [PX]  - VAN DER GEIZE R. ET AL., "Targeted Disruption of the kstD Gene Encoding a 3-Ketosteroid delta1-Dehydrogenase Isoenzyme of Rhodococcus erythropolis Strain SQ1.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (200005), vol. 66, no. 5, pages 2029 - 2036, XP002157019 [PX] 1-11,13 * the whole document *

DOI:   http://dx.doi.org/10.1128/AEM.66.5.2029-2036.2000
 [A]  - DROBNIC K., "Steroid 1,2-dehydrogenase; Nocardia opaca 3-oxosteroid delta(1)-dehydrogenase gene, complete cds.", EMBL DATABASE ENTRY NO59422; ACCESSION NO. U59422, (19960625), XP002157020 [A] 14
 [A]  - DZIADEK J. ET AL, "Arthrobacter simplex ksdI genes and three open reading frames", EMBL DATABASE ENTRY ASZ93338; ACCESSION NO. Z93338, (19970325), XP002157027 [A] 15
Examination   - KIESLICH (1985) J. Basic Microbiol. 25, 461-474.
    - WOVCHA ET AL. (1979) Biochim. Biophys. Acta 574, 471-479.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.