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Extract from the Register of European Patents

EP About this file: EP1244447

EP1244447 - NOVEL METHODS AND COMPOSITIONS INVOLVING OPIOIDS AND ANTAGONISTS THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.11.2007
Database last updated on 24.04.2024
Most recent event   Tooltip16.11.2007No opposition filed within time limitpublished on 19.12.2007  [2007/51]
Applicant(s)For all designated states
Adolor Corporation
700 Pennsylvania Drive
Exton, PA 19341-1127 / US
[2007/11]
Former [2002/40]For all designated states
Adolor Corporation
620 Pennsylvania Drive
Exton, PA 19341-1127 / US
Inventor(s)01 / FARRAR, John, J.
1066 Bodine Road
Chester Springs, PA 19425 / US
 [2002/40]
Representative(s)WP Thompson
138 Fetter Lane
London EC4A 1BT / GB
[N/P]
Former [2002/40]W.P. THOMPSON & CO.
Eastcheap House Central Approach
Letchworth, Hertfordshire SG6 3DS / GB
Application number, filing date00992256.829.11.2000
[2002/40]
WO2000US42315
Priority number, dateUS1999045080629.11.1999         Original published format: US 450806
[2002/40]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0137785
Date:31.05.2001
Language:EN
[2001/22]
Type: A2 Application without search report 
No.:EP1244447
Date:02.10.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 31.05.2001 takes the place of the publication of the European patent application.
[2002/40]
Type: B1 Patent specification 
No.:EP1244447
Date:10.01.2007
Language:EN
[2007/02]
Search report(s)International search report - published on:US10.01.2002
(Supplementary) European search report - dispatched on:EP25.04.2003
ClassificationIPC:A61K31/445, A61K31/485
[2003/22]
CPC:
A61K31/4748 (EP); A61K31/445 (EP); A61K31/485 (EP);
A61P1/00 (EP); A61P25/02 (EP); A61P43/00 (EP)
C-Set:
A61K31/445, A61K2300/00 (EP);
A61K31/4748, A61K2300/00 (EP);
A61K31/485, A61K2300/00 (EP)
Former IPC [2002/40]A61K31/445
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2002/40]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:NEUE VERFAHREN UND ZUBEREITUNGEN DIE OPIOIDEN UND DEREN ANTAGONISTEN ENTHALTEN[2002/40]
English:NOVEL METHODS AND COMPOSITIONS INVOLVING OPIOIDS AND ANTAGONISTS THEREOF[2002/40]
French:NOUVEAUX PROCEDES ET NOUVELLES COMPOSITIONS COMPRENANT DES OPIOIDES ET DES ANTAGONISTES D'OPIOIDES[2002/40]
Entry into regional phase28.06.2002National basic fee paid 
28.06.2002Search fee paid 
28.06.2002Designation fee(s) paid 
28.06.2002Examination fee paid 
Examination procedure04.06.2001Request for preliminary examination filed
International Preliminary Examining Authority: US
28.06.2002Examination requested  [2002/40]
19.08.2002Amendment by applicant (claims and/or description)
16.07.2003Despatch of a communication from the examining division (Time limit: M06)
04.03.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
14.04.2004Reply to a communication from the examining division
02.02.2005Despatch of a communication from the examining division (Time limit: M06)
03.08.2005Reply to a communication from the examining division
30.03.2006Date of oral proceedings
12.04.2006Minutes of oral proceedings despatched
15.05.2006Communication of intention to grant the patent
13.09.2006Fee for grant paid
13.09.2006Fee for publishing/printing paid
Opposition(s)11.10.2007No opposition filed within time limit [2007/51]
Request for further processing for:14.04.2004Request for further processing filed
14.04.2004Full payment received (date of receipt of payment)
Request granted
25.05.2004Decision despatched
Fees paidRenewal fee
28.06.2002Renewal fee patent year 03
12.11.2003Renewal fee patent year 04
12.11.2004Renewal fee patent year 05
14.11.2005Renewal fee patent year 06
14.11.2006Renewal fee patent year 07
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Documents cited:Search[X]US4457933  (GORDON MAXWELL [US], et al) [X] 1-42 * column 1, line 20 - line 31; example -; claim - *;
 [X]US4582835  (LEWIS JOHN W [GB], et al) [X] 1-42 * examples 1-7; claim - *;
 [X]US4769372  (KREEK MARY J [US]) [X] 1-42 * column 2, line 65 - column 3, line 9; claim - *;
 [X]EP0287339  (LILLY CO ELI [US]) [X] 1-42 * page 28, line 28 - line 38; claims 7,8; table 2 *;
 [X]  - WITTELS B ET AL, "OPIOID ANTAGONIST ADJUNCTS TO EPIDURAL MORPHINE FOR POSTCESAREAN ANALGESIA: MATERNAL OUTCOMES", ANESTHESIA AND ANALGESIA, WILLIAMS AND WILKINS, BALTIMORE, MD, US, (199311), vol. 77, no. 5, ISSN 0003-2999, pages 925 - 932, XP001095958 [X] 1-42 * page 925 * * page 926, column L, paragraph 3 * * page 930, column R, paragraph L - page 931, column L, paragraph 1 *
 [X]  - GERAK L R ET AL, "CHANGES IN SENSITIVITY TO THE RAT-DECREASING EFFECTS OF OPIODIS IN PIGEONS TREATED ACUTELY OR CHRONICALLY WITH NALBUPHINE", BEHAVIOURAL PHARMACOLOGY, RAPID SCIENCE, PUBLISHERS, GB, (199610), vol. 5, no. 7, ISSN 0955-8810, pages 437 - 447, XP008005675 [X] 1-42 * page 439, column L, paragraph 2; figure 1 *
 [XP]  - GEAR R W ET AL, "ACTION OF NALOXONE ON GENDER-DEPENDENT ANALGESIC AND ANTIANALGESIC EFFECTS OF NALBUPHINE IN HUMANS", JOURNAL OF PAIN, SAUNDERS, PHILADELPHIA, PA, US, (20000621), vol. 1, no. 2, ISSN 1526-5900, pages 122 - 127, XP008005634 [XP] 1-42 * page 123, column L, line 4 - line 5; table 1 *

DOI:   http://dx.doi.org/10.1016/S1526-5900(00)90097-X
 [PX]  - VACCARINO A L ET AL, "Endogenous opiates: 1998.", PEPTIDES. UNITED STATES DEC 1999, (199912), vol. 20, no. 12, ISSN 0196-9781, pages 1527 - 1574, XP002236928 [PX] 1-42 * page 1543, column R, lines 5-8 *

DOI:   http://dx.doi.org/10.1016/S0196-9781(99)00166-7
International search[Y]US5250542  (CANTRELL BUDDY E [US], et al);
 [Y]  - "Opiate analgesics", OSOL, Remington's pharmaceutical sciences, (1975), page 1098, XP001149582 [Y] * 15th Edition; page 1098 *
 [Y]  - WINDHOLZ, The merck index, an encyclopedia of chemicals, drugs and biologicals, (19860721), XP002942738 [Y] * 10th edition, no. 2423; page 350 *
Examination   - "Adolor targets pain/itch", WORLD PHARMACEUTICAL NEWS, (19990212), no. 2412
    - "Adolor to Develop Copound to Treat Narcotic-Induced Constipation; In-licensed From Roberts Pharmaceuticals", PR NEWSWIRE, (19980616), page 0616NYTU019
    - ZIMMERMANN ET AL, DRUGS OF THE FUTURE, (1994), vol. 19, no. 12, pages 1078 - 1083
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.