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Extract from the Register of European Patents

EP About this file: EP1148049

EP1148049 - Crystalline R-(R*,R*)$-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- (phenylamino)carbonyl -1H-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin) [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  05.08.2011
Database last updated on 24.04.2024
Most recent event   Tooltip28.10.2011Lapse of the patent in a contracting statepublished on 30.11.2011  [2011/48]
Applicant(s)For all designated states
Warner-Lambert Company LLC
235 East 42nd Street
New York, NY 10017 / US
[2007/08]
Former [2005/22]For all designated states
WARNER-LAMBERT COMPANY LLC
201 Tabor Road
Morris Plains, NJ 07950 / US
Former [2004/51]For all designated states
WARNER-LAMBERT COMPANY
201 Tabor Road
Morris Plains, New Jersey 07950 / US
Former [2001/43]For all designated states
WARNER-LAMBERT COMPANY
201 Tabor Road
Morris Plains New Jersey 07950 / US
Inventor(s)01 / Briggs, Christopher A.
643 East 12th Street
Holland, Michigan 49423 / US
02 / Jennings, Rex Allen
405 Lincoln Avenue
Holland, Michigan 49423 / US
03 / Wade, Robert A.
3882 62nd Street
Holland, Michigan 49423 / US
04 / Harasawa, Kikuko, 202 Liberty Palace
Odakyusagamihara, 18-15 Minamidai
6-chome, Sagamihara-shi, Kanagawa 228 / JP
05 / Ichikawa, Shigeru
D-403 Cl-Heights, 1356 Yamasaki-cho
Machida-shi, Tokyo 195 / JP
06 / Minohara, Kazuo
702 Park Heights Sagamihara, 4-4 Sagamihara
5-chome, Sagamihara shi, Kanagawa 229 / JP
07 / Nakagawa, Shinsuke
303 Seishin-Hills, 14-30 Seishin 7-chome
Sagamihara-shi, Kanagawa 229 / JP
 [2001/43]
Representative(s)Schön, Christoph, et al
Dr. Schön, Neymeyr & Partner mbB
Bavariaring 26
80336 München / DE
[N/P]
Former [2011/18]Schön, Christoph, et al
Dr. Schön & Partner Bavariaring 26
80336 München / DE
Former [2010/01]Schön, Christoph
Kroher-Strobel Rechts- und Patentanwälte Bavariaring 20
80336 München / DE
Former [2001/43]Henkel, Feiler, Hänzel
Möhlstrasse 37
81675 München / DE
Application number, filing date01116338.308.07.1996
[2001/43]
Priority number, dateUS19950001452P17.07.1995         Original published format: US 1452 P
[2001/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1148049
Date:24.10.2001
Language:EN
[2001/43]
Type: B1 Patent specification 
No.:EP1148049
Date:15.12.2004
Language:EN
[2004/51]
Search report(s)(Supplementary) European search report - dispatched on:EP04.09.2001
ClassificationIPC:C07D207/34, A61K31/40
[2001/43]
CPC data not yet available
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/43]
Extension statesLT05.07.2001
LV05.07.2001
SI05.07.2001
TitleGerman:Kristaline (R-(R*,R*))-2-(4-Fluorphenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Sslz (Atorvastatin)[2001/43]
English:Crystalline R-(R*,R*)$-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4- (phenylamino)carbonyl -1H-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)[2001/43]
French:Formes cristallines d'hémi-sel de calcium d'acide r-(r*,r*) -2-(4-fluorophényl)-beta,delta-dihydroxy-5-(1-methyléthyl)-3-phényl-4- (phenylamino)carbonyl -1h-pyrrole-1-heptanoique (atorvastatine)[2007/45]
Former [2001/43]Formes cristallines d'hémi-sel de calcium d'acide r-(r*,r*)]-2-(4-fluorophényl)-beta,delta-dihydroxy-5-(1-methyléthyl)-3-phényl-4- (phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (atorvastatine)
Examination procedure05.07.2001Examination requested  [2001/43]
06.05.2002Despatch of a communication from the examining division (Time limit: M08)
16.01.2003Reply to a communication from the examining division
11.03.2003Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time
19.05.2004Communication of intention to grant the patent
26.08.2004Fee for grant paid
26.08.2004Fee for publishing/printing paid
Parent application(s)   TooltipEP96924368.2  / EP0848705
Opposition(s)Opponent(s)01  14.09.2005    ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Gallagher, Kirk James
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
 [N/P]
Former [2005/45]
Opponent(s)01  14.09.2005    ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
5 Basel Street, P.O. Box 3190
Petah Tiqva 49131 / IL
Opponent's representative
Gallagher, Kirk James
D Young & Co 120 Holborn
London EC1N 2DY / GB
21.10.2005Invitation to proprietor to file observations on the notice of opposition
28.06.2006Reply of patent proprietor to notice(s) of opposition
22.10.2007Date of oral proceedings
26.11.2007Despatch of minutes of oral proceedings
04.02.2008Despatch of communication that the patent will be revoked
24.05.2011Legal effect of revocation of patent [2011/36]
Appeal following opposition10.04.2008Appeal received No.  T0777/08
16.06.2008Statement of grounds filed
24.05.2011Result of appeal procedure: appeal of the proprietor was rejected
24.05.2011Date of oral proceedings
01.06.2011Minutes of the oral proceedings despatched
Fees paidRenewal fee
05.07.2001Renewal fee patent year 03
05.07.2001Renewal fee patent year 04
05.07.2001Renewal fee patent year 05
05.07.2001Renewal fee patent year 06
14.05.2003Renewal fee patent year 07
30.07.2003Renewal fee patent year 08
29.07.2004Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.07.200207   M06   Fee paid on   14.05.2003
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Lapses during opposition  TooltipCH15.12.2004
LI15.12.2004
[2011/48]
Documents cited:Search[A]EP0409281  (WARNER LAMBERT CO [US]) [A] 1-14 * example 10 *;
 [A]WO9416693  (WARNER LAMBERT CO [US]) [A] 1-14* example A *;
 [A]  - BAUMANN K L ET AL, "THE CONVERGENT SYNTHESIS OF CI-981, AN OPTICALLY ACTIVE, HIGHLY POTENT, TISSUE SELECTIVE INHIBITOR OF HMG-COA REDUCTASE", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (19920421), vol. 33, no. 17, ISSN 0040-4039, pages 2283 - 2284, XP000608147 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0040-4039(00)74190-6
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.