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Extract from the Register of European Patents

EP About this file: EP1214938

EP1214938 - Modulation of cellular response to external stimuli [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  05.05.2006
Database last updated on 02.08.2024
Most recent event   Tooltip07.07.2007Change - inventorpublished on 08.08.2007  [2007/32]
Applicant(s)For all designated states
Fred Hutchinson Cancer Research Center
1124 Columbia Street
Seattle
Washington 98104 / US
[N/P]
Former [2002/25]For all designated states
Fred Hutchinson Cancer Research Center
1124 Columbia Street
Seattle Washington 98104 / US
Inventor(s)01 / Bianco, James A.
10453 Maplewood Place SW
Seattle, Washington 98146 / US
02 / Bursten, Stuart L.
22287 Mulholland Hwy Suite 225
Calbasas, CA 91302 / US
03 / Singer, Jack W.
3515 East Spring Street
Seattle, Washington 98122 / US
 [2007/32]
Former [2002/37]01 / Bianco, James A.
10453 Maplewood Place SW
Seattle, Washington 98146 / US
02 / Bursten, Stuart L.
22287 Mulholland Hwy Suite #225
Calbasas, CA 91302 / US
03 / Singer, Jack W.
3515 East Spring Street
Seattle, Washington 98122 / US
Former [2002/25]01 / Bianco, James A.
2920 Alki Avenue
Seattle, Washington 98116 / US
02 / Bursten, Stuart L.
36116 S.E. 89th Place
Snoqualmie, Washington 98065 / US
03 / Singer, Jack W.
3515 East Spring Street
Seattle, Washington 98122 / US
Representative(s)Schneider, Michael, et al
HAMMONDS
Karl-Scharnagl-Ring 7
80539 München / DE
[N/P]
Former [2004/38]Schneider, Michael, et al
HAMMONDS, Karl-Scharnagl-Ring 7
80539 München / DE
Former [2004/14]Harris-Fox, Kathleen Dona, et al
Hammonds 7 Devonshire Square Cutlers Gardens
London EC2M 4YH / GB
Former [2002/25]McNally, Roisin, et al
SCEPTRE 165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date01126058.522.05.1992
[2002/25]
Priority number, dateUS1991070499224.05.1991         Original published format: US 704992
US1991073222716.07.1991         Original published format: US 732227
[2002/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1214938
Date:19.06.2002
Language:EN
[2002/25]
Type: A3 Search report 
No.:EP1214938
Date:06.08.2003
[2003/32]
Search report(s)(Supplementary) European search report - dispatched on:EP07.01.2003
ClassificationIPC:A61K31/522, // (A61K31/522, 31:496)
[2003/32]
CPC:
A61K31/47 (EP); A61K31/52 (EP); A61K31/522 (EP);
A61P35/00 (EP); Y02A50/30 (EP)
C-Set:
A61K31/47, A61K2300/00 (EP);
A61K31/522, A61K2300/00 (EP);
A61K31/52, A61K2300/00 (EP);
A61K31/52, A61K31/47 (EP)
Former IPC [2002/25]A61K31/52
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   MC,   NL,   SE [2004/18]
Former [2002/25]AT,  BE,  CH,  DE,  DK,  ES,  FR,  GB,  GR,  IT,  LI,  LU,  MC,  NL,  SE 
TitleGerman:Modulation der zellulären Reaktion auf externe Stimuli[2002/25]
English:Modulation of cellular response to external stimuli[2002/25]
French:Modulation de la réponse cellulaire à des stimuli externes[2002/25]
Examination procedure04.02.2004Examination requested  [2004/15]
22.09.2004Despatch of a communication from the examining division (Time limit: M06)
01.04.2005Reply to a communication from the examining division
09.06.2005Despatch of a communication from the examining division (Time limit: M06)
20.12.2005Application deemed to be withdrawn, date of legal effect  [2006/23]
25.01.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2006/23]
Parent application(s)   TooltipEP92915059.7  / EP0573617
Fees paidRenewal fee
31.12.2001Renewal fee patent year 03
31.12.2001Renewal fee patent year 04
31.12.2001Renewal fee patent year 05
31.12.2001Renewal fee patent year 06
31.12.2001Renewal fee patent year 07
31.12.2001Renewal fee patent year 08
31.12.2001Renewal fee patent year 09
31.12.2001Renewal fee patent year 10
14.05.2002Renewal fee patent year 11
07.05.2003Renewal fee patent year 12
05.05.2004Renewal fee patent year 13
13.05.2005Renewal fee patent year 14
27.03.2006Renewal fee patent year 15
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]JPH0344324  ;
 [A]EP0267676  (BEECHAM WUELFING GMBH & CO KG [DE], et al) [A] 1,3 * the whole document *;
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 [E]EP0490181  (HOECHST ROUSSEL PHARMA [US]) [E] 1-3,6 * the whole document *;
 [E]EP0493682  (HOECHST ROUSSEL PHARMA [US]) [E] 1-3,6 * the whole document *;
 [E]EP0514789  (HOECHST AG [DE]) [E] 1-3 * the whole document *;
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 [A]  - TAKAHASHI G W ET AL, "PENTOXIFYLLINE PTX SUPPRESSES GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR GM-CSF INDUCTION OF TUMOR NECROSIS FACTOR-ALPHA TNFALPHA WITH MINIMAL INHIBITION OF GM-CSF INDUCED PROLIFERATION.", JOINT MEETING OF THE ASSOCIATION OF AMERICAN PHYSICIANS, THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, AND THE AMERICAN FEDERATION FOR CLINICAL RESEARCH, SEATTLE, WASHINGTON, USA, MAY 3-6, 1991. CLIN RES. (1991) 39 (2), 210A., XP008008395 [A] 1,6 * the whole document *
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 [A]  - RAO K M K ET AL, "PENTOXIFYLLINE INHIBITS INTERLEUKIN-2 RECEPTOR EXPRESSION IN PHASTIMULATED HUMAN LYMPHOCYTES", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, US, (199002), vol. 4, no. 3, ISSN 0892-6638, page A338,AN420, XP001108902 [A] 1,6 * abstract 420 *
 [A]  - HOLLER E ET AL, "INCREASED SERUM LEVELS OF TUMOR NECROSIS FACTOR ALPHA PRECEDE MAJOR COMPLICATIONS OF BONE MARROW TRANSLANTATION", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, (19900215), vol. 75, no. 4, ISSN 0006-4971, pages 1011 - 1016, XP008008234 [A] 1,2 * the whole document *
 [X]  - GASTPAR H, "THE INHIBITION OF CANCER CELL STICKINESS BY THE METHYLXANTINE DERIVATIVE PENTOXIFYLLINE (BL 191)", THROMBOSIS RESEARCH, TARRYTOWN, NY, US, (197409), vol. 5, no. 3, ISSN 0049-3848, pages 277 - 289, XP008008371 [X] 1,3,6 * the whole document *

DOI:   http://dx.doi.org/10.1016/0049-3848(74)90167-4
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 [X]  - KOSTAKIS A J ET AL, "PROLONGATION OF CARDIAC AND RENAL ALLOGRAFT SURVIVAL BY PENTOXIFYLLINE IN RATS", IRCS MEDICAL SCIENCE, XX, XX, (198201), vol. 10, no. 1, pages 77 - 78, XP008008236 [X] 1,3,6 * the whole document *
 [X]  - SHAW D R ET AL, "NON-VIRAL INFECTIONS OF THE NERVOUS SYSTEM", CURRENT OPINION IN NEUROLOGY AND NEUROSURGERY, CURRENT SCIENCE, GB, (199104), vol. 4, no. 2, ISSN 0951-7383, pages 227 - 231, XP008009122 [X] 1,6 * the whole document *
 [X]  - HAIDL G ET AL, "GUIDELINES FOR DRUG TREATMENT OF MALE INFERTILITY", DRUGS, ADIS INTERNATIONAL LTD, AT, (1991), vol. 41, no. 1, ISSN 0012-6667, pages 60 - 68, XP008009125 [X] 1,3,6 * page 64, column R, paragraph 1.9 *

DOI:   http://dx.doi.org/10.2165/00003495-199141010-00006
 [X]  - ECKMANN L, "PENTOXIFYLLIN HEMMT DEN TUMOR NECROSIS FACTOR!", THERAPIEWOCHE, KARLSRUHE, DE, (1991), vol. 41, no. 8, ISSN 0040-5973, pages 428 - 430, XP008009123 [X] 1-3,6 * the whole document *
 [PX]  - BIANCO J A ET AL, "PHASE I-II TRIAL OF PENTOXIFYLLINE FOR THE PREVENTION OF TRANSPLANT-RELATED TOXICITIES FOLLOWING BONE MARROW TRANSPLANTATION", BLOOD, W.B. SAUNDERS, PHILADELPHIA, VA, US, (19910901), vol. 78, no. 5, ISSN 0006-4971, pages 1205 - 1211, XP008000764 [PX] 1-3,6 * the whole document *
 [PX]  - BIANCO J A ET AL, "COMBINED PHARMACOLOGIC BLOCKADE OF TNF-ALPHA WITH PENTOXIFYLLINE (PTX), PREDNISONE (PDR) AND CIPROFLOXICIN (CIPRO) REDUCES REGIMEN RELATED TOXICITY (RRT) AND ACCELERATES ENGRAFTMENT IN PATIENTS UNDERGOINING BONE MARROW TRANSPLANTATION (BMT)", EXPERIMENTAL HEMATOLOGY, NEW YORK, NY, US, (199107), vol. 19, ISSN 0301-472X, page 553,AN363, XP008008567 [PX] 1-8 * the whole document *
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 [PX]  - BIANCO J A ET AL, "PENTOXIFYLLINE PTX REDUCES TRANSPLANT RELATED TOXICITIES TRT AND IMPROVES SURVIVAL IN PATIENTS UNDERGOING BONE MARROW TRANSPLANTATION BMT.", 20TH ANNUAL MEETING OF THE INTERNATIONAL SOCIETY FOR EXPERIMENTAL HEMATOLOGY, PARMA, ITALY, JULY 21-25, 1991. EXP HEMATOL (N Y). (1991) 19 (6), 570., XP008008393 [PX] 1-3,6 * the whole document *
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 [X]  - PATENT ABSTRACTS OF JAPAN, vol. 0, no. 0, & JP03044324 A 19910226 (KAZUOKI TSUCHIYA) [X] 1 * abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.