blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1343872

EP1343872 - CULTURING TISSUE USING MAGNETICALLY GENERATED MECHANICAL STRESSES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.06.2014
Database last updated on 15.06.2024
Most recent event   Tooltip03.07.2015Lapse of the patent in a contracting state
New state(s): TR		published on 05.08.2015  [2015/32]
Applicant(s)For all designated states
MICA BioSystems Limited
23 Arley Road
Solihull
West Midlands B91 1NJ / GB
[2013/19]
Former [2003/38]For all designated states
KEELE UNIVERSITY
Keele
Staffordshire ST5 5BG / GB
Inventor(s)01 / EL-HAJ, Alicia, Jennifer, Hafeeza
Beardhough Cottage
Whitle Road
New Mills, High Peak SK22 4EQ / GB
02 / DOBSON, Jon, Paul
Claremount Brook Lane
Endon, Stoke-on-Trent ST9 9EZ / GB
 [2013/33]
Former [2003/38]01 / EL-HAJ, Alicia, Jennifer, Hafeeza
Beardhough Cottage, Whitle Road
New Mills, High Peak SK22 4EQ / GB
02 / DOBSON, Jon, Paul
Claremount Brook Lane
Endon, Stoke-on-Trent ST9 9EZ / GB
Representative(s)Clegg, Richard Ian
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
[N/P]
Former [2013/33]Clegg, Richard Ian
Mewburn Ellis LLP
33 Gutter Lane
London
EC2V 8AS / GB
Former [2008/25]Clegg, Richard Ian
Mewburn Ellis LLP York House 23 Kingsway
London WC2B 6HP / GB
Former [2006/45]Harrison Goddard Foote
Orlando House 11c Compstall Road Marple Bridge
Stockport SK6 5HH / GB
Former [2003/38]Harrison Goddard Foote
31 St Saviourgate
York Y01 8NQ / GB
Application number, filing date01272072.819.12.2001
[2003/38]
WO2001GB05606
Priority number, dateGB2000003146222.12.2000         Original published format: GB 0031462
GB2000003165123.12.2000         Original published format: GB 0031651
US20010267032P07.02.2001         Original published format: US 267032 P
[2003/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO02051985
Date:04.07.2002
Language:EN
[2002/27]
Type: A2 Application without search report 
No.:EP1343872
Date:17.09.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 04.07.2002 takes the place of the publication of the European patent application.
[2003/38]
Type: B1 Patent specification 
No.:EP1343872
Date:14.08.2013
Language:EN
[2013/33]
Search report(s)International search report - published on:EP16.01.2003
ClassificationIPC:C12N5/22
[2013/18]
CPC:
C12M35/04 (EP); C12N13/00 (KR); C12M1/42 (KR);
C12M21/08 (EP); C12M35/06 (EP); C12N5/0062 (EP);
C12N5/0652 (KR); B82Y5/00 (KR) (-)
Former IPC [2003/38]C12N5/08
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/38]
TitleGerman:GEWEBEKULTUR UNTER MAGNETISCH AUSGELÖSTEM MECHANISCHEM STRESS[2003/38]
English:CULTURING TISSUE USING MAGNETICALLY GENERATED MECHANICAL STRESSES[2003/38]
French:CULTURE DE TISSUS AU MOYEN DE CONTRAINTES MECANIQUES GENEREES DE MANIERE MAGNETIQUE[2003/38]
Entry into regional phase14.07.2003National basic fee paid 
14.07.2003Designation fee(s) paid 
14.07.2003Examination fee paid 
Examination procedure16.07.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
14.07.2003Amendment by applicant (claims and/or description)
14.07.2003Examination requested  [2003/38]
04.04.2006Despatch of a communication from the examining division (Time limit: M06)
06.10.2006Reply to a communication from the examining division
13.07.2009Despatch of a communication from the examining division (Time limit: M06)
11.05.2010Reply to a communication from the examining division
18.01.2012Despatch of a communication from the examining division (Time limit: M06)
04.09.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
14.11.2012Reply to a communication from the examining division
18.02.2013Communication of intention to grant the patent
28.06.2013Fee for grant paid
28.06.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.04.2006
Opposition(s)15.05.2014No opposition filed within time limit [2014/30]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
14.11.2012Request for further processing filed
14.11.2012Full payment received (date of receipt of payment)
Request granted
22.11.2012Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
11.05.2010Request for further processing filed
11.05.2010Full payment received (date of receipt of payment)
Request granted
31.05.2010Decision despatched
Fees paidRenewal fee
24.11.2003Renewal fee patent year 03
14.12.2004Renewal fee patent year 04
22.12.2005Renewal fee patent year 05
13.12.2006Renewal fee patent year 06
12.12.2007Renewal fee patent year 07
23.12.2008Renewal fee patent year 08
21.12.2009Renewal fee patent year 09
21.12.2010Renewal fee patent year 10
20.12.2011Renewal fee patent year 11
14.03.2013Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
31.12.201212   M06   Fee paid on   14.03.2013
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
ES14.08.2013
FI14.08.2013
IT14.08.2013
MC14.08.2013
NL14.08.2013
SE14.08.2013
TR14.08.2013
GR15.11.2013
PT16.12.2013
IE19.12.2013
LU19.12.2013
[2015/32]
Former [2014/48]AT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
ES14.08.2013
FI14.08.2013
IT14.08.2013
MC14.08.2013
NL14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
IE19.12.2013
LU19.12.2013
Former [2014/38]AT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
ES14.08.2013
FI14.08.2013
IT14.08.2013
MC14.08.2013
NL14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
LU19.12.2013
Former [2014/24]AT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
ES14.08.2013
FI14.08.2013
IT14.08.2013
NL14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/22]AT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
FI14.08.2013
NL14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/21]AT14.08.2013
BE14.08.2013
CY14.08.2013
DK14.08.2013
FI14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/18]AT14.08.2013
BE14.08.2013
CY14.08.2013
FI14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/14]CY19.06.2013
AT14.08.2013
BE14.08.2013
FI14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/12]CY19.06.2013
AT14.08.2013
FI14.08.2013
SE14.08.2013
GR15.11.2013
PT16.12.2013
Former [2014/11]CY19.06.2013
AT14.08.2013
FI14.08.2013
SE14.08.2013
PT16.12.2013
Former [2014/10]CY19.06.2013
AT14.08.2013
SE14.08.2013
PT16.12.2013
Former [2014/09]AT14.08.2013
SE14.08.2013
PT16.12.2013
Former [2014/08]PT16.12.2013
Cited inInternational search[X]US5486457  (BUTLER JAMES P [US], et al) [X] 1-4 * figure 1; examples 1,2 *;
 [X]  - YUGE LOUIS ET AL, "Differentiation of myoblasts is accelerated in culture in a magnetic field.", IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY ANIMAL, (200006), vol. 36, no. 6, ISSN 1071-2690, pages 383 - 386, XP001061490 [X] 1,2,4,9,12 * page 383, column R; figure 1 * * page 385 *

DOI:   http://dx.doi.org/10.1290/1071-2690(2000)036<0383:DOMIAI>2.3.CO;2
 [X]  - LIU MINGYAO ET AL, "Bio-stretch, a computerized cell strain apparatus for three-dimensional organotypic cultures.", IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY ANIMAL, (199902), vol. 35, no. 2, ISSN 1071-2690, pages 87 - 93, XP001080069 [X] 1,2,6,8-10,12 * page 87, column R, paragraph L - page 88, column L, paragraph 1; figures 1,3 * * page 89 - page 92 *
 [X]  - KASPAR D ET AL, "Dynamic cell stretching increases human osteoblast proliferation and CICP synthesis but decreases osteocalcin synthesis and alkaline phosphatase activity.", JOURNAL OF BIOMECHANICS, (200001), vol. 33, no. 1, ISSN 0021-9290, pages 45 - 51, XP002203098 [X] 1,2,6-9,12,14,15,19 * page 46; table 1 * * page 48; figure 2 *

DOI:   http://dx.doi.org/10.1016/S0021-9290(99)00171-2
 [A]  - BOTTLANG M ET AL, "A cell strain system for small homogeneous strain applications.", BIOMEDIZINISCHE TECHNIK, (199711), vol. 42, no. 11, ISSN 0013-5585, pages 305 - 309, XP001080015 [A] * page 306 *
 [X]  - GLOGAUER MICHAEL ET AL, "A new method for application of force to cells via ferric oxide beads.", PFLUEGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY, (199801), vol. 435, no. 2, ISSN 0031-6768, pages 320 - 327, XP002203099 [X] 1-4,9,12,19 * page 320, column R - page 321, column R, paragraph 2; figure 1 * * page 323 * * page 324, column L, paragraph 2 - page 325, column L, paragraph 2 *

DOI:   http://dx.doi.org/10.1007/s004240050518
    [ ] - GLOGAUER,M. ET AL., "Magnetic fields applied to collagen-coated ferric oxide beads induce stretch-activated Ca-2+ flux in fibroblasts.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1995), Database accession no. PREV199698605117, XP002203103 [ ] * abstract *
    [ ] - AMERICAN JOURNAL OF PHYSIOLOGY, (1995), vol. 269, no. 5 PART 1, ISSN 0002-9513, pages C1093 - C1104
 [X]  - SMALT R ET AL, "Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain.", AMERICAN JOURNAL OF PHYSIOLOGY, (199710), vol. 273, no. 4 PART 1, ISSN 0002-9513, pages E751 - E758, XP002203100 [X] 1,2,6-8,12,14,15 * page E752; figure 1 *
 [X]  - WANG NING ET AL, "Contribution of intermediate filaments to cell stiffness, stiffening, and growth.", AMERICAN JOURNAL OF PHYSIOLOGY, (200007), vol. 279, no. 1 Part 1, ISSN 0002-9513, pages C188 - C194, XP002203101 [X] 1-4 * page C189, column L *
 [X]  - WANG NING, "Mechanical interactions among cytoskeletal filaments.", HYPERTENSION (DALLAS), (199807), vol. 32, no. 1, ISSN 0194-911X, pages 162 - 165, XP002203102 [X] 1-4 * page 162, column R, paragraph 2 - page 163, column L, paragraph 1 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.