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Extract from the Register of European Patents

EP About this file: EP1273655

EP1273655 - PROCESS FOR PRODUCING RECOMBINANT PROTEIN [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  10.02.2006
Database last updated on 03.06.2024
Most recent event   Tooltip10.02.2006Application deemed to be withdrawnpublished on 29.03.2006  [2006/13]
Applicant(s)For all designated states
Takeda Pharmaceutical Company Limited
1-1, Doshomachi 4-chome, Chuo-ku
Osaka / JP
[N/P]
Former [2005/01]For all designated states
Takeda Pharmaceutical Company Limited
1-1, Doshomachi 4-chome Chuo-ku
Osaka / JP
Former [2003/02]For all designated states
Takeda Chemical Industries, Ltd.
1-1 Doshomachi 4-chome, Chuo-ku
Osaka-shi, Osaka 541-0045 / JP
Inventor(s)01 / YAMADA, Takao
4-3-26, Hitotsuya
Matsubara-shi, Osaka 580-0003 / JP
02 / TSUJI, Isamu
13-27, Segawa 5-chome
Mino-shi, Osaka 562-0045 / JP
03 / MATSUI, Hideki
16-1-708, Namiki 4-chome
Tsukuba-shi, Ibaraki 305-0044 / JP
 [2003/02]
Representative(s)Lewin, John Harvey
TGRD (Europe)
Intellectual Property Department
61 Aldwych
London WC2B 4AE / GB
[N/P]
Former [2003/02]Lewin, John Harvey
Takeda Patent Office, 11-12 Charles II Street
London SW1Y 4QU / GB
Application number, filing date01917667.630.03.2001
[2003/02]
WO2001JP02712
Priority number, dateJP2000009789130.03.2000         Original published format: JP 2000097891
[2003/02]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0175095
Date:11.10.2001
Language:EN
[2001/41]
Type: A1 Application with search report 
No.:EP1273655
Date:08.01.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 11.10.2001 takes the place of the publication of the European patent application.
[2003/02]
Search report(s)International search report - published on:JP11.10.2001
(Supplementary) European search report - dispatched on:EP17.06.2004
ClassificationIPC:C12N15/09, C12P21/00, C12P21/02, // C07K14:715, C12P21:02, C12R1:19
[2003/02]
CPC:
C07K14/70575 (EP,US); C12P21/02 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/02]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERFAHREN ZUR HERSTELLUNG EINES REKOMBINANTEN PROTEINS[2003/02]
English:PROCESS FOR PRODUCING RECOMBINANT PROTEIN[2003/02]
French:PROCEDE DE PRODUCTION DE PROTEINE DE RECOMBINAISON[2003/02]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase06.09.2002Translation filed 
06.09.2002National basic fee paid 
06.09.2002Search fee paid 
06.09.2002Designation fee(s) paid 
06.09.2002Examination fee paid 
Examination procedure09.05.2001Request for preliminary examination filed
International Preliminary Examining Authority: JP
06.09.2002Examination requested  [2003/02]
10.03.2005Despatch of a communication from the examining division (Time limit: M06)
21.09.2005Application deemed to be withdrawn, date of legal effect  [2006/13]
25.10.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2006/13]
Fees paidRenewal fee
06.09.2002Renewal fee patent year 03
15.03.2004Renewal fee patent year 04
14.03.2005Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO9603432  (CIBA GEIGY AG [CH], et al);
 [X]  - REYDA SABINE ET AL, "cDNA cloning, bacterial expression, in vitro renaturation and affinity purification of the zinc endopeptidase astacin", BIOCHEMICAL JOURNAL, (19991215), vol. 344, no. 3, ISSN 0264-6021, pages 851 - 857, XP002279353 [X] 1-8 * page 853, column R, paragraphs 1,2 * * page 856, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1042/0264-6021:3440851
 [X]  - TSUMOTO K ET AL, "Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagent-application to a human single-chain Fv fragment", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, (19981001), vol. 219, no. 1-2, ISSN 0022-1759, pages 119 - 129, XP004142546 [X] 1-8 * See whole document and in particular items 2.2, 2.3, 3.1 and 3.2 *

DOI:   http://dx.doi.org/10.1016/S0022-1759(98)00127-6
 [A]  - FRANKEL A E ET AL, "High-Level Expression and Purification of the Recombinant Diphtheria Fusion Toxin DTGM for PHASE I Clinical Trials", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, US, (199906), vol. 16, no. 1, ISSN 1046-5928, pages 190 - 201, XP004441698 [A] 1-8 * page 192, column R, paragraphs 3,4 *

DOI:   http://dx.doi.org/10.1006/prep.1999.1071
 [A]  - STOYAN T ET AL, "RECOMBINANT SOLUBLE HUMAN INTERLEUKIN-6 RECEPTOR. EXPRESSION IN ESCHERICHIA COLI, RENATURATION AND PURIFICATION", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, (19930801), vol. 216, no. 1, ISSN 0014-2956, pages 239 - 245, XP002047601 [A] 1-8 * page 240, column R, paragraphs 2,3 *

DOI:   http://dx.doi.org/10.1111/j.1432-1033.1993.tb18138.x
International search[X]JPH10191989  (TAKEDA CHEMICAL INDUSTRIES LTD);
 [Y]WO9803648  (TAKEDA CHEMICAL INDUSTRIES LTD [JP], et al);
 [Y]WO9640736  (CELTRIX PHARMA [US]);
 [A]WO9829559  (HOECHST MARION ROUSSEL LTD [JP], et al)
 [Y]  - JEREMY A. HARROP ET AL., "Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (199810), vol. 273, no. 42, pages 27548 - 27556, XP002947574

DOI:   http://dx.doi.org/10.1074/jbc.273.42.27548
 [Y]  - MAURI D.N. ET AL., "LIGHT, a new member of the TNF superfamily and lymphotoxin alpha are ligands for herpesvirus entry mediator", IMMUNITY, (1998), vol. 8, no. 1, pages 21 - 30, XP002947575

DOI:   http://dx.doi.org/10.1016/S1074-7613(00)80455-0
 [A]  - YIFAN ZHAI ET AL., "LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer", J. CLIN. INVEST., (1998), vol. 102, no. 6, pages 1142 - 1151, XP002947576

DOI:   http://dx.doi.org/10.1172/JCI3492
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.