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EP About this file: EP1268416

EP1268416 - 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS AND THEIR THERAPEUTIC USES [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 01.08.2008 Database last updated on 03.09.2024
Most recent event Tooltip	13.08.2010	Lapse of the patent in a contracting state New state(s): TR	published on 15.09.2010 [2010/37]
Applicant(s)	For all designated states WISCONSIN ALUMNI RESEARCH FOUNDATION 614 North Walnut Street Madison, WI 53705-7365 / US
	[2007/39]
Former [2003/01]	For all designated states WISCONSIN ALUMNI RESEARCH FOUNDATION 614 North Walnut Street Madison, Wisconsin 53705-7365 / US
Inventor(s)	01 / DELUCA, Hector, F. 1809 Highway BB Deerfield, WI 53531 / US
	02 / SICINSKI, Rafal, R. ul. Waszyngtona 33m. 150 PL-04-030 Warsaw / PL
	[2003/01]
Representative(s)	Benson, John Everett, et al J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB
	[N/P]
Former [2008/43]	Benson, John Everett, et al J. A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ / GB
Former [2007/24]	Benson, John Everett, et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ / GB
Former [2003/01]	Ellis-Jones, Patrick George Armine, et al J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5JJ / GB
Application number, filing date	01920897.4	29.03.2001
	[2003/01]
	WO2001US10317
Priority number, date	US20000540686	31.03.2000 Original published format: US 540686
	[2003/01]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO0174766
	Date:	11.10.2001
	Language:	EN
	[2001/41]
	Type:	A1 Application with search report
	No.:	EP1268416
	Date:	02.01.2003
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 11.10.2001 takes the place of the publication of the European patent application.
	[2003/01]
	Type:	B1 Patent specification
	No.:	EP1268416
	Date:	26.09.2007
	Language:	EN
	[2007/39]
Search report(s)	International search report - published on:	EP	11.10.2001
Classification	IPC:	C07C401/00, A61K31/59, A61P3/02, A61P3/14, A61P17/06, A61P35/00, A61P35/02	[2003/01]
	CPC:	C07C401/00 (EP,KR,US); A61P1/00 (EP); A61P13/08 (EP); A61P15/00 (EP); A61P17/00 (EP); A61P17/06 (EP); (+) A61P17/10 (EP); A61P17/14 (EP); A61P19/00 (EP); A61P19/02 (EP); A61P19/10 (EP); A61P25/00 (EP); A61P29/00 (EP); A61P3/02 (EP); A61P3/10 (EP); A61P3/14 (EP); A61P35/00 (EP); A61P35/02 (EP); A61P37/06 (EP); A61P5/18 (EP); A61P7/00 (EP); A61P9/10 (EP); A61P9/12 (EP); C07F7/1804 (EP,US); Y02P20/55 (EP,US) (-)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/01]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	2-ALKYLIDENE-19-NOR-VITAMIN D VERBINDUNGEN UND IHRE THERAPEUTISCHE VERWENDUNGEN	[2003/01]
	English:	2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS AND THEIR THERAPEUTIC USES	[2003/01]
	French:	COMPOSES 2-ALKYLIDENE-19-NOR- DE LA VITAMINE D ET LEURS UTILISATIONS THERAPEUTIQUES	[2003/01]
Entry into regional phase	14.10.2002	National basic fee paid
	14.10.2002	Designation fee(s) paid
	14.10.2002	Examination fee paid
Examination procedure	24.10.2001	Request for preliminary examination filed International Preliminary Examining Authority: EP
	14.10.2002	Amendment by applicant (claims and/or description)
	14.10.2002	Examination requested [2003/01]
	31.03.2004	Despatch of a communication from the examining division (Time limit: M04)
	06.08.2004	Reply to a communication from the examining division
	19.03.2007	Communication of intention to grant the patent
	09.07.2007	Fee for grant paid
	09.07.2007	Fee for publishing/printing paid
Opposition(s)	27.06.2008	No opposition filed within time limit [2008/36]
Fees paid	Renewal fee
	11.03.2003	Renewal fee patent year 03
	15.03.2004	Renewal fee patent year 04
	14.03.2005	Renewal fee patent year 05
	09.03.2006	Renewal fee patent year 06
	14.03.2007	Renewal fee patent year 07
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	CY	26.09.2007
	TR	26.09.2007
	GR	27.12.2007
	PT	26.02.2008
	MC	31.03.2008
	[2010/37]
Former [2009/33]	CY	26.09.2007
	GR	27.12.2007
	PT	26.02.2008
	MC	31.03.2008
Former [2008/46]	GR	27.12.2007
	PT	26.02.2008
	MC	31.03.2008
Former [2008/26]	GR	27.12.2007
	PT	26.02.2008
Former [2008/19]	GR	27.12.2007
Cited in	International search	[Y]US4851401 (DELUCA HECTOR F [US], et al) [Y] 1-30,39-42 * page 2, paragraph 2; examples 5,7,8 ** column 11, paragraph 2 *;
		[XY]WO9841501 (WISCONSIN ALUMNI RES FOUND [US]) [X] 32-38,43 * the whole document * [Y] 1-30,39-42;
		[Y]US5981780 (DELUCA HECTOR F [US]) [Y] 1-30,39-42 * column 4, lines 6-39 * * column 6, line 10 * * column 7, paragraph 1 * * column 9, paragraph L * * column 10, paragraph 2 *;
		[XY] - SICINSKI ET AL, "New 1alpha-25-Dihydroxy-19-norvitamin D3 Compounds of High Biological Activity: Synthesis and Biological Evaluation of 2-Hydroxymethyl, 2-Methyl, and 2-Methylene Analogues", JOURNAL OF MEDICINAL CHEMISTRY,AMERICAN CHEMICAL SOCIETY. WASHINGTON,US, (19981022), vol. 41, ISSN 0022-2623, pages 4662 - 4674, XP002106465 [X] 31-38,43 * page 4663; figure 1; examples 6A,6B * * page 4668; table 1 * * page 4669, column 1, paragraph 2; table 2 * [Y] 1-30,39-42 DOI: http://dx.doi.org/10.1021/jm9802618
		[Y] - YANG, WEN ET AL, "20-Epi analogues of 1,25-Dihydroxyvitamin D3 are highly potent inducers of DRIP coactivator complex binding to the vitamin D3 receptor", J. BIOL. CHEM. (1999), 274(24), 16838-16845, XP002172427 [Y] 1-30,39-42 * page 16839, column 1, paragraph 1 * * compound MC1627; page 16843, column 2, paragraph 2 * DOI: http://dx.doi.org/10.1074/jbc.274.24.16838

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