EP About this file: EP1268786

EP1268786 - USE OF P-SELECTIN GLYCOPROTEIN LIGAND-1 (PSGL-1) AND FRAGMENTS THEREOF FOR THE INHIBITION OF THROMBOSIS [Right-click to bookmark this link]
Status	The application has been refused Status updated on 14.10.2005 Database last updated on 05.04.2025
Most recent event Tooltip	25.07.2008	Change - representative	published on 27.08.2008 [2008/35]
Applicant(s)	For all designated states Genetics Institute, LLC 87 Cambridge Park Drive Cambridge, MA 02140 / US
	[2003/06]
Former [2003/01]	For all designated states GENETICS INSTITUTE, INC. 87 Cambridge Park Drive Cambridge, Massachusetts 02140 / US
Inventor(s)	01 / EPPIHIMER, Michael, J. 51 Faith Drive Derry, NH 03038 / US
	02 / SCHAUB, Robert, G. 118 Jeremy Hill Road Pelham, NH 03076 / US
	03 / HARRIS, Alan, S. 197 Haggetts Pond Road Andover, MA 01810 / US
	[2003/01]
Representative(s)	Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München / DE
	[N/P]
Former [2008/35]	Vossius & Partner Siebertstrasse 3 81675 München / DE
Former [2003/01]	VOSSIUS & PARTNER Siebertstrasse 4 81675 München / DE
Application number, filing date	01920923.8	02.04.2001
	[2003/01]
	WO2001US10622
Priority number, date	US20000193787P	31.03.2000 Original published format: US 193787 P
	[2003/01]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO0175107
	Date:	11.10.2001
	Language:	EN
	[2001/41]
	Type:	A2 Application without search report
	No.:	EP1268786
	Date:	02.01.2003
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 11.10.2001 takes the place of the publication of the European patent application.
	[2003/01]
Search report(s)	International search report - published on:	EP	11.04.2002
Classification	IPC:	C12N15/12, C07K14/47, C12N15/62, A61K38/17, A61P7/02	[2003/01]
	CPC:	C07K14/70596 (EP,US); A61P43/00 (EP); A61P7/02 (EP); C07K2319/00 (EP,US); C07K2319/30 (EP,US)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE, TR [2003/01]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	VERWENDUNG VON PSGL-1 (P-SELECTIN GLYCOPROTEIN LIGAND-1) UND DESSEN FRAGMENTE ZUR HEMMUNG VON THROMBOSE	[2003/01]
	English:	USE OF P-SELECTIN GLYCOPROTEIN LIGAND-1 (PSGL-1) AND FRAGMENTS THEREOF FOR THE INHIBITION OF THROMBOSIS	[2003/01]
	French:	INHIBITION DE LA THROMBOSE GRACE A UN TRAITEMENT REPOSANT SUR DES ANTAGONISTES DE LA P-SELECTINE	[2003/01]
Entry into regional phase	28.10.2002	National basic fee paid
	28.10.2002	Designation fee(s) paid
	28.10.2002	Examination fee paid
Examination procedure	22.10.2001	Request for preliminary examination filed International Preliminary Examining Authority: EP
	28.10.2002	Amendment by applicant (claims and/or description)
	28.10.2002	Examination requested [2003/01]
	25.02.2003	Despatch of a communication from the examining division (Time limit: M06)
	30.07.2003	Reply to a communication from the examining division
	17.09.2003	Despatch of a communication from the examining division (Time limit: M06)
	29.03.2004	Reply to a communication from the examining division
	24.11.2004	Date of oral proceedings
	20.12.2004	Despatch of communication that the application is refused, reason: substantive examination [2005/48]
	20.12.2004	Minutes of oral proceedings despatched
	20.09.2005	Application refused, date of legal effect [2005/48]
Appeal following examination	28.02.2005	Appeal received No. T0706/05
	20.09.2005	Result of appeal procedure: appeal of the applicant inadmissible
Divisional application(s)	EP04027786.5 / EP1518931
Fees paid	Renewal fee
	07.04.2003	Renewal fee patent year 03
	06.04.2004	Renewal fee patent year 04
	04.04.2005	Renewal fee patent year 05
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Cited in	International search	[Y]WO9808949 (GENETICS INST [US]) [Y] 9-14 * page 6, line 28 - page 7, line 18 * * page 17, line 24 - page 18, line 8 * * example 5D *;
		[XY] - ZHANG HONG ET AL, "Anti-thrombotic effect of a recombinant soluble P-selectin Glycoprotein Ligand-1 chimera in a rat model of thrombosis.", CIRCULATION, 72nd Scientific Sessions of the American Heart Association;Atlanta, Georgia, USA; November 7-10, 1999, (19991102), vol. 100, no. 18 SUPPL., ISSN 0009-7322, page I.471, XP001034261 [X] 1-20 * abstract * [Y] 9-14
		[XY] - ZHANG HONG ET AL, "A recombinant soluble P-selectin glycoprotein ligand-1 chimera has a thrombolytic effect in a rat model of thrombosis.", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY., 29th Annual Scientific Session of the American College of Cardiology.;Anaheim, California, USA; March 12-15, 2000, (200002), vol. 35, no. 2 suppl. A, ISSN 0735-1097, page 280A, XP001034262 [X] 1-16,18-20 * abstract * [Y] 9-14
		[XY] - EPPIHIMER M J ET AL, "Role of selectin inhibitors in the pathogenesis of deep vein thrombosis.", JOURNAL OF LEUKOCYTE BIOLOGY, 15th International Congress of the Society for Leukocyte Biology with the European Macrophage Study Group;Cambridge, England, UK; September 22-26, 1999, (1999), no. SUPPL., ISSN 0741-5400, page 27, XP001034258 [X] 1-20 * abstract * [Y] 9-14
		[XY] - EPPIHIMER MICHAEL J ET AL, "Effect of recombinant PSGL-1 (rPSGL-Ig) on vascular injury and thrombosis following venous stasis.", CIRCULATION, 72nd Scientific Sessions of the American Heart Association;Atlanta, Georgia, USA; November 7-10, 1999, (19991102), vol. 100, no. 18 SUPPL., ISSN 0009-7322, page I.812, XP001034260 [X] 1-20 * abstract * [Y] 9-14
		[XY] - WAKEFIELD THOMAS W ET AL, "Venous thrombosis prophylaxis by inflammatory inhibition without anticoagulation therapy.", JOURNAL OF VASCULAR SURGERY, (200002), vol. 31, no. 2, ISSN 0741-5214, pages 309 - 324, XP001034251 [X] 1-20 * page 314, column R, paragraph 2 - page 318, column R, paragraph 2 * [Y] 9-14 DOI: http://dx.doi.org/10.1016/S0741-5214(00)90162-9
		[A] - KUMAR ANJALI ET AL, "Recombinant soluble form of PSGL-1 accelerates thrombolysis and prevents reocclusion in a porcine model.", CIRCULATION, (19990316), vol. 99, no. 10, ISSN 0009-7322, pages 1363 - 1369, XP001034254 [A] 1-20 * see Conclusions of the Abstract; page 1367, column R, paragraph 1 *
		[PX] - EPPIHIMER MICHAEL J ET AL, "P-selectin-dependent inhibition of thrombosis during venous stasis.", ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, (200011), vol. 20, no. 11, ISSN 1079-5642, pages 2483 - 2488, XP001034249 [PX] 1-20 * the whole document *

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