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Extract from the Register of European Patents

EP About this file: EP1299109

EP1299109 - BIFUNCTIONAL ANTIBIOTICS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.05.2010
Database last updated on 05.07.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
THE SCRIPPS RESEARCH INSTITUTE
10550 North Torrey Pines Road
La Jolla, CA 92037 / US
[2009/29]
Former [2003/15]For all designated states
The Scripps Research Institute
10550 North Torrey Pines Road
La Jolla, CA 92037 / US
Inventor(s)01 / WONG, Chi-Huey
P.O. Box 8154
Rancho Santa Fe, CA 92067 / US
02 / SUCHECK, Steven
5809 Menorca
San Diego, CA 92124 / US
 [2003/15]
Representative(s)Hedley, Nicholas James Matthew, et al
Kilburn & Strode LLP
Lancon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2008/34]Hedley, Nicholas James Matthew, et al
Kilburn & Strode 20 Red Lion Street London
WC1R 4PJ / GB
Former [2003/15]Hedley, Nicholas James Matthew, et al
Kilburn & Strode 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date01927464.627.04.2001
[2003/15]
WO2001US40611
Priority number, dateUS20000200084P27.04.2000         Original published format: US 200084 P
[2003/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0180863
Date:01.11.2001
Language:EN
[2001/44]
Type: A1 Application with search report 
No.:EP1299109
Date:09.04.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 01.11.2001 takes the place of the publication of the European patent application.
[2003/15]
Type: B1 Patent specification 
No.:EP1299109
Date:15.07.2009
Language:EN
[2009/29]
Search report(s)International search report - published on:US01.11.2001
(Supplementary) European search report - dispatched on:EP26.04.2005
ClassificationIPC:A61K31/70, A61P31/04
[2009/04]
CPC:
C07H15/234 (EP,US); A61K31/70 (EP,US); A61K31/704 (EP,US);
A61K47/552 (EP,US); A61P31/04 (EP); C07H15/224 (EP,US);
C07H15/232 (EP,US); Y02A50/30 (EP,US) (-)
Former IPC [2003/15]A61K31/70
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/15]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:BIFUNKTIONELLE ANTIBIOTIKA[2003/15]
English:BIFUNCTIONAL ANTIBIOTICS[2003/15]
French:ANTIBIOTIQUES BIFONCTIONNELS[2003/15]
Entry into regional phase27.11.2002National basic fee paid 
27.11.2002Search fee paid 
27.11.2002Designation fee(s) paid 
27.11.2002Examination fee paid 
Examination procedure01.08.2002Request for preliminary examination filed
International Preliminary Examining Authority: US
27.11.2002Examination requested  [2003/15]
12.06.2006Despatch of a communication from the examining division (Time limit: M06)
06.12.2006Reply to a communication from the examining division
08.12.2008Cancellation of oral proceeding that was planned for 09.12.2008
08.12.2008Minutes of oral proceedings despatched
09.12.2008Date of oral proceedings
09.12.2008Date of oral proceedings (cancelled)
30.12.2008Communication of intention to grant the patent
08.04.2009Fee for grant paid
08.04.2009Fee for publishing/printing paid
Opposition(s)16.04.2010No opposition filed within time limit [2010/25]
Fees paidRenewal fee
14.04.2003Renewal fee patent year 03
15.04.2004Renewal fee patent year 04
13.04.2005Renewal fee patent year 05
17.03.2006Renewal fee patent year 06
12.04.2007Renewal fee patent year 07
28.03.2008Renewal fee patent year 08
16.04.2009Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT15.07.2009
BE15.07.2009
CY15.07.2009
DK15.07.2009
FI15.07.2009
IT15.07.2009
NL15.07.2009
SE15.07.2009
TR15.07.2009
GR16.10.2009
ES26.10.2009
PT15.11.2009
[2012/47]
Former [2012/37]AT15.07.2009
BE15.07.2009
CY15.07.2009
DK15.07.2009
FI15.07.2009
IT15.07.2009
NL15.07.2009
SE15.07.2009
GR16.10.2009
ES26.10.2009
PT15.11.2009
Former [2011/14]AT15.07.2009
BE15.07.2009
DK15.07.2009
FI15.07.2009
IT15.07.2009
NL15.07.2009
SE15.07.2009
GR16.10.2009
ES26.10.2009
PT15.11.2009
Former [2010/47]AT15.07.2009
BE15.07.2009
DK15.07.2009
FI15.07.2009
NL15.07.2009
SE15.07.2009
GR16.10.2009
ES26.10.2009
PT15.11.2009
Former [2010/25]AT15.07.2009
BE15.07.2009
DK15.07.2009
FI15.07.2009
NL15.07.2009
SE15.07.2009
ES26.10.2009
PT15.11.2009
Former [2010/20]AT15.07.2009
DK15.07.2009
FI15.07.2009
NL15.07.2009
SE15.07.2009
ES26.10.2009
PT15.11.2009
Former [2010/16]AT15.07.2009
FI15.07.2009
NL15.07.2009
SE15.07.2009
ES26.10.2009
PT15.11.2009
Former [2010/10]AT15.07.2009
FI15.07.2009
NL15.07.2009
SE15.07.2009
ES26.10.2009
Former [2010/09]AT15.07.2009
FI15.07.2009
SE15.07.2009
ES26.10.2009
Former [2010/08]AT15.07.2009
SE15.07.2009
ES26.10.2009
Documents cited:Search[X]  - K MICHAEL AND ALL., "Enhanced RNA binding of dimerized aminoglucosides", BIOORGANIC AND MEDICINAL CHEMISTRY, (1999), vol. 7, pages 1361 - 1371, XP002323123 [X] 1,2 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0968-0896(99)00071-1
International search[X]  - SUCHECK S.J. ET AL., "Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (2000), vol. 122, pages 5230 - 5231, XP002945710

DOI:   http://dx.doi.org/10.1021/ja000575w
 [X]  - TOK J.B.-H., "Enhanced binding of aminoglycoside dimers to a 'dimerized' A-site 16S rRNA construct", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (20000717), vol. 10, pages 1593 - 1595, XP002945709

DOI:   http://dx.doi.org/10.1016/S0960-894X(00)00299-7
 [X]  - WANG H. ET AL., "Dimeric aminoglycosides: Design, synthesis and RNA binding", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (1997), vol. 7, no. 14, pages 1951 - 1956, XP002945708

DOI:   http://dx.doi.org/10.1016/S0960-894X(97)00339-9
Examination   - FOURMY D.; RECT M.I.; PUGLISI J.D., "Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA", JOURNAL OF MOLECULAR BIOLOGY, (1998), vol. 277, pages 347 - 362, XP004456034

DOI:   http://dx.doi.org/10.1006/jmbi.1997.1552
    - SUNDRAM U.N.; GRIFFIN J.H., "Novel vancomycin dimers with activty against vancomycin-resistant enterococci", JOURNAL OF AMERICAL CHEMICAL SOCIETY, US, (1996), vol. 118, pages 13107 - 13108, XP002037250

DOI:   http://dx.doi.org/10.1021/ja9621298
by applicant   - MICHAEL ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, (1999), vol. 7, pages 1361 - 1371
    - FOURMY ET AL., J. MOLE. BIOL., (1998), vol. 277, pages 347 - 362
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.