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Extract from the Register of European Patents

EP About this file: EP1287153

EP1287153 - METHODS AND COMPOSITIONS FOR EFFICIENT GENE TRANSFER USING TRANSCOMPLEMENTARY VECTORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.08.2010
Database last updated on 15.08.2024
Most recent event   Tooltip19.10.2012Lapse of the patent in a contracting state
New state(s): TR		published on 21.11.2012  [2012/47]
Applicant(s)For all designated states
Human Gene Therapy Research Institute
1415 Woodland Avenue
Des Moines, IA 50309-9976 / US
[2003/10]
Inventor(s)01 / Ramsey, William J.
New Link Genetics, 2901 South Loop Dr., Suite 3900
Ames, IA 50010 / US
02 / Higginbotham, James N.
New Link Genetics, 2901 South Loop Dr.,Suite 3900
Ames, IA 50010 / US
03 / Link, Charles J.
1415 Woodland Avenue
Des Moines, IA 50309-9976 / US
 [2003/25]
Former [2003/10]01 / Ramsey, William J.
Suite 3550, 2901 South Loop Drive
Ames, IA 50010 / US
02 / Higginbotham, James N.
Suite 3550, 2901 South Loop Drive
Ames, IA 50010 / US
03 / Link, Charles J.
1415 Woodland Avenue
Des Moines, IA 50309-9976 / US
Representative(s)Bentham, Andrew
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2003/10]Bentham, Andrew
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
Application number, filing date01939734.831.05.2001
[2003/10]
WO2001US17524
Priority number, dateUS20000208248P31.05.2000         Original published format: US 208248 P
[2003/10]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0192550
Date:06.12.2001
Language:EN
[2001/49]
Type: A2 Application without search report 
No.:EP1287153
Date:05.03.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 06.12.2001 takes the place of the publication of the European patent application.
[2003/10]
Type: B1 Patent specification 
No.:EP1287153
Date:30.09.2009
Language:EN
[2009/40]
Search report(s)International search report - published on:EP28.03.2002
ClassificationIPC:C12N15/86, C12N15/861, C12N15/867, C12N15/869, C12N5/10, A61K48/00, G01N33/15
[2003/10]
CPC:
C12N15/86 (EP,US); A61K48/00 (EP,US); C12N7/00 (EP,US);
A61K38/00 (EP,US); C12N2710/10343 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/10]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:METHODE UND ZUSAMMENSETZUNGEN FÜR EFFIZIENTEN GENTRANSFER DURCH TRANSCOMPLEMENTIERENDE VEKTOREN[2003/10]
English:METHODS AND COMPOSITIONS FOR EFFICIENT GENE TRANSFER USING TRANSCOMPLEMENTARY VECTORS[2003/10]
French:PROCEDES ET COMPOSITIONS DE TRANSFERT EFFICACE DE GENE UTILISANT DES VECTEURS TRANSCOMPLEMENTAIRES[2003/10]
Entry into regional phase19.12.2002National basic fee paid 
19.12.2002Designation fee(s) paid 
19.12.2002Examination fee paid 
Examination procedure28.12.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.12.2002Amendment by applicant (claims and/or description)
19.12.2002Examination requested  [2003/10]
16.07.2007Despatch of a communication from the examining division (Time limit: M06)
14.01.2008Reply to a communication from the examining division
07.03.2008Despatch of a communication from the examining division (Time limit: M04)
11.07.2008Reply to a communication from the examining division
20.04.2009Communication of intention to grant the patent
17.08.2009Fee for grant paid
17.08.2009Fee for publishing/printing paid
Opposition(s)01.07.2010No opposition filed within time limit [2010/36]
Fees paidRenewal fee
13.05.2003Renewal fee patent year 03
26.04.2004Renewal fee patent year 04
12.05.2005Renewal fee patent year 05
10.05.2006Renewal fee patent year 06
14.05.2007Renewal fee patent year 07
31.03.2008Renewal fee patent year 08
12.05.2009Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
IT30.09.2009
NL30.09.2009
SE30.09.2009
TR30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
IE31.05.2010
LU31.05.2010
MC31.05.2010
[2012/47]
Former [2012/43]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
IT30.09.2009
NL30.09.2009
SE30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
IE31.05.2010
LU31.05.2010
MC31.05.2010
Former [2011/19]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
IT30.09.2009
NL30.09.2009
SE30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
IE31.05.2010
MC31.05.2010
Former [2011/14]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
IT30.09.2009
NL30.09.2009
SE30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
MC31.05.2010
Former [2011/03]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
NL30.09.2009
SE30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
MC31.05.2010
Former [2010/47]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
NL30.09.2009
SE30.09.2009
GR31.12.2009
ES10.01.2010
PT01.02.2010
Former [2010/35]AT30.09.2009
BE30.09.2009
CY30.09.2009
DK30.09.2009
FI30.09.2009
NL30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/32]AT30.09.2009
BE30.09.2009
CY30.09.2009
FI30.09.2009
NL30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/30]AT30.09.2009
BE30.09.2009
CY30.09.2009
FI30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/28]BE30.09.2009
CY30.09.2009
FI30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/25]CY30.09.2009
FI30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/22]FI30.09.2009
SE30.09.2009
ES10.01.2010
PT01.02.2010
Former [2010/19]FI30.09.2009
SE30.09.2009
ES10.01.2010
Former [2010/09]FI30.09.2009
SE30.09.2009
Former [2010/08]SE30.09.2009
Cited inInternational search[X]WO9822143  (UNIV ALABAMA RES FOUND [US]) [X] 1-5,7,10,13-15,17,20-22,24,27,30-32,34 * examples 3,5,21; claim 13 *;
 [Y]WO9946371  (UNIV TEXAS [US], et al) [Y] 12,29,37,38,40-42 * page 11; claims 17-19 *;
 [X]WO0017376  (US HEALTH [US], et al) [X] 1-5,11-14 * page 17; claim - * * page 23 *;
 [PX]EP1059356  (UNIV PARIS CURIE [FR]) [PX] 1-3,10,13,14 * claims 23,33,37 *;
 [XY]  - ALEMANY R. ET AL., "Complementary adenoviral vectors for oncolysis", CANCER GENE THERAPY, (199901), vol. 6, no. 1, pages 21 - 25, XP001037527 [X] 1-5,10,13,20-22,27,30 * the whole document * [Y] 12,29,37

DOI:   http://dx.doi.org/10.1038/sj.cgt.7700001
 [X]  - FENG M ET AL, "STABLE IN VIVO GENE TRANSDUCTION VIA A NOVEL ADENOVIRAL/RETROVIRAL CHIMERIC VECTOR", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, (199709), vol. 15, no. 9, ISSN 1087-0156, pages 866 - 870, XP000867001 [X] 1-5,7,10,13-15,17,20-22,24,27,30-32,34 * figure 1 *

DOI:   http://dx.doi.org/10.1038/nbt0997-866
 [Y]  - CHO J-Y. ET AL., "Expression and activity of human Na+/I- symporter in human glioma cells by adenovirus-madiated gene delivery.", GENE THERAPY, (200005), vol. 7, pages 740 - 749, XP000137550 [Y] 38,40-42 * the whole document *
 [X]  - COSSET F-L ET AL, "A NEW AVIAN LEUKOSIS VIRUS-BASED PACKAGING CELL LINE THAT USES TWO SEPARATE TRANSCOMPLEMENTING HELPER GENOMES", JOURNAL OF VIROLOGY, NEW YORK, US, US, (19900301), vol. 64, no. 3, ISSN 0022-538X, pages 1070 - 1078, XP000564826 [X] 1-3,10,13,14 * the whole document *
 [X]  - BRIDGE E ET AL, "ADENOVIRUS EARLY REGION 4 AND VIRAL DNA SYNTHESIS", VIROLOGY, ACADEMIC PRESS,ORLANDO, US, (19930401), vol. 193, no. 2, ISSN 0042-6822, pages 794 - 801, XP002051623 [X] 1-4,8,13-16,18,20,21,23,25,30,31,33,35 * the whole document *

DOI:   http://dx.doi.org/10.1006/viro.1993.1188
 [XY]  - NOGUIEZ-HELLIN P ET AL, "GENERATION D'UN PROVIRUS RECOMBINANT DEFECTIF COMPLEMENTABLE EN TRANS ET VEHICULANT UN TRANSGENE GENERATION OF A TRANSCOMPLEMENTABLE DEFECTIVE RECOMBINANT PROVIRUSTRANSDUCING A FOREIGN GENE", COMPTES RENDUS DES SEANCES DE L'ACADEMIE DES SCIENCES. SERIE III: SCIENCES DE LA VIE, ELSEVIER, AMSTERDAM, NL, (1996), vol. 319, no. 1, ISSN 0764-4469, pages 45 - 50, XP000578113 [X] 1-3,12-14 * the whole document * [Y] 4-11,15-39
 [Y]  - DION L.D. ET AL, "Quantitative and in vivo activity of adenoviral-producing cells made by cotransduction of a replication-defective adenovirus and a replication-enabling plasmid.", CANCER GENE THER., (1996), vol. 3, no. 4, pages 230 - 237, XP001037532 [Y] 1-42 * the whole document *
 [Y]  - KETNER G ET AL, "Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids", NUCLEIC ACIDS RESEARCH, IRL PRESS LTD., OXFORD, GB, (1989), vol. 17, no. 8, ISSN 0305-1048, pages 3037 - 3048, XP002003252 [Y] 1-42 * the whole document *
 [A]  - MANDELL R ET AL, "GENE THERAPY OF CANCER BY RETROVIRAL TRANSFER AND EXPRESSION OF THE RAT SODIUM/IODIDE SYMPORTER (NIS)", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, (19970301), vol. 38, ISSN 0197-016X, page 381, XP002074718
 [A]  - LANUTI M ET AL, "EVALUATION OF AN E1E4-DELETED ADENOVIRUS EXPRESSING THE HERPES SIMPLEX THYMIDINE KINASE SUICIDE GENE IN CANCER GENE THERAPY", HUMAN GENE THERAPY, XX, XX, (19990210), vol. 10, ISSN 1043-0342, pages 463 - 475, XP000995599

DOI:   http://dx.doi.org/10.1089/10430349950018904
 [A]  - OKADA ET AL, "Efficient directional cloning of recombinant adenovirus vectors using DNA-protein complex", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, (19980415), vol. 26, no. 8, ISSN 0305-1048, pages 1947 - 1950, XP002121030

DOI:   http://dx.doi.org/10.1093/nar/26.8.1947
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.