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Extract from the Register of European Patents

EP About this file: EP1309617

EP1309617 - PROCESS FOR THE SELECTION OF HIV-1 SUBTYPE C ISOLATES, SELECTED HIV-1 SUBTYPE ISOLATES, THEIR GENES AND MODIFICATIONS AND DERIVATIVES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.07.2011
Database last updated on 12.07.2024
Most recent event   Tooltip27.09.2013Lapse of the patent in a contracting state
New state(s): TR		published on 30.10.2013  [2013/44]
Applicant(s)For all designated states
MEDICAL RESEARCH COUNCIL
Francie Van Zijl Drive, Parow Valley
7500 Cape Town / ZA
For all designated states
University of Cape Town
Observatory
7500 Cape Town / ZA
For all designated states
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
CB 4100, Bynum Hall
Chapel Hill, NC 27599-4100 / US
For all designated states
Alphavax, Inc.
P.O. Box 110307, 2 Triangle Drive
Research Triangle Park, NC 27709-0307 / US
[2010/37]
Former [2010/32]For all designated states
MEDICAL RESEARCH COUNCIL
Francie Van Zijl Drive, Parow Valley
7500 Cape Town / ZA
For all designated states
University of Cape Town
Observatory
7500 Cape Town / ZA
For all designated states
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
CB 4100, Bynum Hall
Chapel Hill, NC 27599-4100 / US
For all designated states
Alphavax, Inc.
P.O. Box 110307, 2 Triangle Drive
Research Triangle Park, NC 27709-0307 / US
Former [2003/20]For all designated states
MEDICAL RESEARCH COUNCIL
Francie Van Zijl Drive, Parow Valley
7500 Cape Town / ZA
For all designated states
University of Cape Town
Observatory
7500 Cape Town / ZA
For all designated states
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Office of Research Services, CB 4100, 300 Bynum Hall
Chapel Hill, NC 27599-4100 / US
For all designated states
Alphavax, Inc.
P.O. Box 110307, 2 Triangle Drive
Research Triangle Park, NC 27709-0307 / US
Inventor(s)01 / WILLIAMSON, Carolyn
University of Cape Town, Observatory
7500 Cape Town / ZA
02 / SWANSTROM, Ronald, Ivar
University of North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-4100 / US
03 / MORRIS, Lynn Nat. Inst. for Communicable Diseases
Private Bag X 4, Modderfontein Road
2131 Sandringham / ZA
04 / KARIM, Salim, Abdool, University of Natal
Francis Stock Bldg,Room 21 232 King George V Ave.
Durban 4001 / ZA
05 / JOHNSTON, Robert, Edward
University of North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-410 0 / US
 [2010/17]
Former [2003/50]01 / WILLIAMSON, Carolyn
University of Cape Town, Observatory
7500 Cape Town / ZA
02 / SWANSTROM, Ronald, Ivar
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-4100 / US
03 / MORRIS, Lynn Nat. Inst. for Communicable Diseases
Private Bag X 4, Modderfontein Road
2131 Sandringham / ZA
04 / KARIM, Salim, Abdool, University of Natal
Francis Stock Bldg,Room 21 232 King George V Ave.
Durban 4001 / ZA
05 / JOHNSTON, Robert, Edward
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-410 0 / US
Former [2003/44]01 / WILLIAMSON, Carolyn
University of Cape Town, Observatory
7500 Cape Town / ZA
02 / SWANSTROM, Ronald, Ivar
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-4100 / US
03 / MORRIS, Lynn Nat. Inst. for Communicable Diseases
Private Bag X 4, Modderfontein Road
2131 Sandringham / ZA
04 / KARIM, Salim, Abdool
Francie van Zijl Drive Parow Valley
7500 Cape Town / ZA
05 / JOHNSTON, Robert, Edward
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-410 0 / US
Former [2003/20]01 / WILLIAMSON, Carolyn
University of Cape Town, Observatory
7500 Cape Town / ZA
02 / SWANSTROM, Ronald, Ivar
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-4100 / US
03 / MORRIS, Lynn
National Institute for Virology Modderfontein Road
2131 Sandringham / ZA
04 / KARIM, Salim, Abdool
Francie van Zijl Drive Parow Valley
7500 Cape Town / ZA
05 / JOHNSTON, Robert, Edward
North Carolina at Chapel Hill CB 4100 Bynum Hall
Chapel Hill, NC 27599-410 0 / US
Representative(s)Albutt, Jodie
Dehns
St Bride's House
10 Salisbury Square
London
EC4Y 8JD / GB
[N/P]
Former [2009/43]Albutt, Jodie
Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Former [2003/20]Jones, Elizabeth Louise
Frank B. Dehn & Co., 179 Queen Victoria Street
London EC4V 4EL / GB
Application number, filing date01956723.909.07.2001
[2003/20]
WO2001IB01208
Priority number, dateUS20000216995P07.07.2000         Original published format: US 216995 P
ZA2000000343710.07.2000         Original published format: ZA 200003437
ZA2000000492415.09.2000         Original published format: ZA 200004924
[2003/20]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0204494
Date:17.01.2002
Language:EN
[2002/03]
Type: A2 Application without search report 
No.:EP1309617
Date:14.05.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 17.01.2002 takes the place of the publication of the European patent application.
[2003/20]
Type: B1 Patent specification 
No.:EP1309617
Date:15.09.2010
Language:EN
[2010/37]
Search report(s)International search report - published on:EP13.03.2003
ClassificationIPC:C07K14/16, C12N7/00, C12N7/02
[2003/20]
CPC:
C07K14/005 (EP); A61K39/12 (EP); A61K39/21 (EP);
C12N7/00 (EP); A61K39/00 (EP); C12N2740/16034 (EP);
C12N2740/16051 (EP); C12N2740/16122 (EP); C12N2740/16134 (EP);
C12N2740/16222 (EP); C12N2740/16234 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/20]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:VERFAHREN ZUR SELEKTION VON HIV-1 SUBTYP C-ISOLATEN, SOLCHE ISOLATEN, SOWIE DEREN GENE, MODIFIKATIONEN UND ABLEITUNGEN[2003/20]
English:PROCESS FOR THE SELECTION OF HIV-1 SUBTYPE C ISOLATES, SELECTED HIV-1 SUBTYPE ISOLATES, THEIR GENES AND MODIFICATIONS AND DERIVATIVES THEREOF[2003/20]
French:PROCEDE DE SELECTION D'ISOLATS DE SOUS-TYPE C DU VIH-1, ISOLATS DE SOUS-TYPE C DU VIH-1 SELECTIONNES, GENES, MODIFICATIONS ET DERIVES[2003/20]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase07.02.2003National basic fee paid 
07.02.2003Designation fee(s) paid 
07.02.2003Examination fee paid 
Examination procedure06.02.2002Request for preliminary examination filed
International Preliminary Examining Authority: EP
07.02.2003Amendment by applicant (claims and/or description)
07.02.2003Examination requested  [2003/20]
03.08.2005Despatch of a communication from the examining division (Time limit: M06)
22.03.2006Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
01.06.2006Reply to a communication from the examining division
17.08.2006Despatch of a communication from the examining division (Time limit: M08)
27.04.2007Reply to a communication from the examining division
04.02.2008Despatch of a communication from the examining division (Time limit: M02)
27.03.2008Reply to a communication from the examining division
26.05.2009Despatch of a communication from the examining division (Time limit: M02)
05.08.2009Reply to a communication from the examining division
03.11.2009Communication of intention to grant the patent
26.02.2010Fee for grant paid
26.02.2010Fee for publishing/printing paid
Opposition(s)16.06.2011No opposition filed within time limit [2011/34]
Request for further processing for:01.06.2006Request for further processing filed
01.06.2006Full payment received (date of receipt of payment)
Request granted
04.07.2006Decision despatched
Fees paidRenewal fee
25.07.2003Renewal fee patent year 03
27.07.2004Renewal fee patent year 04
25.07.2005Renewal fee patent year 05
24.07.2006Renewal fee patent year 06
26.07.2007Renewal fee patent year 07
24.07.2008Renewal fee patent year 08
24.07.2009Renewal fee patent year 09
23.07.2010Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT15.09.2010
BE15.09.2010
CY15.09.2010
DK15.09.2010
FI15.09.2010
NL15.09.2010
SE15.09.2010
TR15.09.2010
GR16.12.2010
ES26.12.2010
PT17.01.2011
[2013/44]
Former [2012/03]AT15.09.2010
BE15.09.2010
CY15.09.2010
DK15.09.2010
FI15.09.2010
NL15.09.2010
SE15.09.2010
GR16.12.2010
ES26.12.2010
PT17.01.2011
Former [2011/40]AT15.09.2010
BE15.09.2010
CY15.09.2010
DK15.09.2010
FI15.09.2010
IT15.09.2010
NL15.09.2010
SE15.09.2010
GR16.12.2010
ES26.12.2010
PT17.01.2011
Former [2011/31]AT15.09.2010
BE15.09.2010
CY15.09.2010
FI15.09.2010
IT15.09.2010
NL15.09.2010
SE15.09.2010
GR16.12.2010
ES26.12.2010
PT17.01.2011
Former [2011/24]AT15.09.2010
CY15.09.2010
FI15.09.2010
NL15.09.2010
SE15.09.2010
GR16.12.2010
PT17.01.2011
Former [2011/15]AT15.09.2010
CY15.09.2010
FI15.09.2010
SE15.09.2010
GR16.12.2010
Former [2011/13]AT15.09.2010
CY15.09.2010
FI15.09.2010
Former [2011/10]AT15.09.2010
FI15.09.2010
Former [2011/08]AT15.09.2010
Cited inInternational search[X]  - DE BAAR M.P. ET AL., "Subtype-specific sequence variation of the HIV type 1 long terminal repeat and primer-binding site", AIDS RES. AND HUMAN RETROVIR., (20000320), vol. 16, no. 5, XP002221002 [X] 1-4,27 * the whole document *

DOI:   http://dx.doi.org/10.1089/088922200309160
 [A]  - TSCHERNING C. ET AL., "Differences in chemokine coreceptor usage between genetyc subtypes of HIV-1", VIROLOGY, (1998), vol. 241, pages 181 - 188, XP002221003 [A] 1-7,9,11,13-30 * the whole document *

DOI:   http://dx.doi.org/10.1006/viro.1997.8980
 [X]  - NOVITSKY VA ET AL, "Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: a set of 23 full-length clones from Botswana", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 73, no. 5, ISSN 0022-538X, (199905), Database accession no. Q9WF90, pages 4427 - 4432, URL: EMBL, XP002144689 [X] 14-16
    [ ] - "Gag polyprotein", EMBL PROTEINS, (19991101), Database accession no. Q9WF90, URL: EMBL, XP002221006 [ ] * 95.7% identity with seq. 1 * * 94.5% identity with seq. 5 * * 94.8% identity with seq. 12 *
    [ ] - "Gag-pol polyprotein", EMBL PROTEINS, (19991101), Database accession no. Q9WF89, URL: EMBL, XP002221007 [ ] * aa 457-1139: 86.8% identity with seq. 7 (aa 170-850) *
    [ ] - "HIV-1 isolate C-96BW04.02", EMBL DNA, (19990311), Database accession no. AF110962, URL: EMBL, XP002221008 [ ] * nt 1582-3703: 72% identity with seq. 6 (nt 449-2571) *
    [ ] - "HIV-1 isolate C-96BW11.04 country Botswana", EMBL DNA, (19990311), Database accession no. AF110969, URL: EMBL, XP002221009 [ ] * nt 6152-8143: 89% identity with seq. 10 (nt 591-2579) *
    [ ] - "HIV-1 isolate C-96BW15B03 country Botswana", EMBL DNA, Database accession no. AF110973, URL: EMBL, XP002221010 [ ] * nt 280-1760: 75% identity with seq. 4 (nt 91-1571) *
 [X]  - GAO F ET AL, "Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID networks for HIV isolation and characterization", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (199603), vol. 70, no. 3, ISSN 0022-538X, pages 1651 - 1667, XP002123321 [X] 20
    [ ] - "Envelope glycoprotein", EMBL PROTEINS, (19961101), Database accession no. Q70014, URL: EMBL, XP002221011 [ ] * aa 215-554:85% identity with seq. 3 * * aa 215-348+469-563 about 85% identity with seq. 14 *
 [X]  - LOLE K S ET AL, "FULL-LENGTH HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GENOMES FROM SUBTYPE C-INFECTED SEROCONVERTERS IN INDIA, WITH EVIDENCE OF INTERSUBTYPE RECOMBINATION", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (199901), vol. 73, no. 1, ISSN 0022-538X, pages 152 - 160, XP002929279 [X] 22,23
    [ ] - "envelope protein", EMBL PROTEINS, (19981101), Database accession no. O90096, URL: EMBL, XP002221012 [ ] * 83% identity with seq. 9 * * 82% identity with seq. 11 (aa 24-857) *
 [PX]  - LEIGH BROWN A.J. ET AL., "Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites.", J. VIROL., (200011), vol. 74, no. 22, pages 10269 - 10273, XP002221004 [PX] 18

DOI:   http://dx.doi.org/10.1128/JVI.74.22.10269-10273.2000
    [ ] - "Reverse transcriptase", EMBL PROTEINS, (20010601), Database accession no. Q99FC3, URL: EMBL, XP002221013 [ ] * aa25-302: 96.7% identity with seq. 2 * * aa 26-302: 97.5% identity with seq.13 *
 [A]  - "HIV-1 isolate BU/91/07, envelope", EMBL DNA, (19960102), Database accession no. HI1U39249, URL: EMBL, XP002221014 [A] 13 * nt420-2559: 70% identity with seq. 8 (nt 402-2541) *
 [A]  - VAN HARMELEN J.H. ET AL., "A predominantly HIV Type 1 subtype C-restricted epidemic in South African urban populations", AIDS RES. AND HUMAN RETROVIR., (1999), vol. 15, no. 4, pages 395 - 398, XP002221005

DOI:   http://dx.doi.org/10.1089/088922299311376
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.