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Extract from the Register of European Patents

EP About this file: EP1423693

EP1423693 - ERYTHROPOIETIN AND ANTI-TUMOR NECROSIS FACTOR ALPHA COMBINATION THERAPY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  13.11.2009
Database last updated on 14.09.2024
Most recent event   Tooltip13.11.2009Application deemed to be withdrawnpublished on 16.12.2009  [2009/51]
13.11.2009Change - representativepublished on 16.12.2009  [2009/51]
Applicant(s)For all designated states
Ortho-McNeil Pharmaceutical, Inc.
U.S. Route 202
Raritan, NJ 08869 / US
[2004/23]
Inventor(s)01 / ITRI, Loretta
6 Kimball Circle
Westfield, NJ 07090 / US
 [2004/23]
Representative(s)Mercer, Christopher Paul, et al
Carpmaels & Ransford LLP
One Southampton Row
London
WC1B 5HA / GB
[N/P]
Former [2009/51]Mercer, Christopher Paul, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Former [2004/23]Mercer, Christopher Paul, et al
Carpmaels & Ransford, 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date01959479.502.08.2001
[2004/23]
WO2001US24384
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO03012432
Date:13.02.2003
Language:EN
[2003/07]
Type: A1 Application with search report 
No.:EP1423693
Date:02.06.2004
Language:EN
The application published by WIPO in one of the EPO official languages on 13.02.2003 takes the place of the publication of the European patent application.
[2004/23]
Search report(s)International search report - published on:US13.02.2003
(Supplementary) European search report - dispatched on:EP04.05.2006
ClassificationIPC:A61K38/18, A61K38/17, A61K39/395, G01N33/00, A01K67/00, A01K67/033, A01K67/027, A01N43/04, A61K31/70, A61K31/52, A61K31/454, A61P35/00
[2006/23]
CPC:
A61K45/06 (EP); A61K31/454 (EP); A61K31/52 (EP);
A61K31/70 (EP); A61K38/1793 (EP); A61K38/1816 (EP);
A61K39/395 (EP); A61P35/00 (EP); A61P7/06 (EP);
C07K2319/30 (EP) (-)
C-Set:
A61K31/454, A61K2300/00 (EP);
A61K31/52, A61K2300/00 (EP);
A61K31/70, A61K2300/00 (EP);
A61K38/1793, A61K2300/00 (EP);
A61K38/1816, A61K2300/00 (EP);
A61K39/395, A61K2300/00 (EP)
(-)
Former IPC [2004/23]G01N33/00, A01K67/00, A01K67/033, A01K67/027, A01N43/04, A61K31/70
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2004/23]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:KOMBINATIONSTHERAPIE MIT ERYTHROPOETIN UND ANTI-TUMORNEKROSE-FAKTOR-ALPHA[2004/23]
English:ERYTHROPOIETIN AND ANTI-TUMOR NECROSIS FACTOR ALPHA COMBINATION THERAPY[2004/23]
French:ERYTHROPOIETINE ET TRAITEMENT DE COMBINAISON ALPHA ANTI-FACTEUR DE NECROSE DES TUMEURS[2004/23]
Entry into regional phase01.03.2004National basic fee paid 
01.03.2004Search fee paid 
01.03.2004Designation fee(s) paid 
01.03.2004Examination fee paid 
Examination procedure28.02.2003Request for preliminary examination filed
International Preliminary Examining Authority: US
01.03.2004Amendment by applicant (claims and/or description)
01.03.2004Examination requested  [2004/23]
02.02.2009Despatch of a communication from the examining division (Time limit: M04)
13.06.2009Application deemed to be withdrawn, date of legal effect  [2009/51]
21.07.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2009/51]
Fees paidRenewal fee
01.03.2004Renewal fee patent year 03
01.03.2004Renewal fee patent year 04
12.08.2005Renewal fee patent year 05
14.08.2006Renewal fee patent year 06
14.08.2007Renewal fee patent year 07
31.03.2008Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.08.200909   M06   Not yet paid
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Documents cited:Search[E]WO0210743  (ORTHO MCNEIL PHARM INC [US]) [E] 1-7 * page 4, line 15 - page 7 * * page 10, line 17 - page 13, line 2; claims 23-28 *;
 [E]WO0236152  (AMGEN INC [US]) [E] 1-7 * page 10, paragraph 5 - page 11, paragraph 4; claims 47-75 * * page 14, paragraph 2 * * page 17, paragraph 2 - page 20 *;
 [Y]  - DEMETRI G D ET AL, "QUALITY-OF-LIFE BENEFIT IN CHEMOTHERAPY PATIENTS TREATED WITH EPOETIN ALFA IS INDEPENDENT OF DISEASE RESPONSE OR TUMOR TYPE: RESULTS FROM A PROSPECTIVE COMMUNITY ONCOLOGY STUDY", JOURNAL OF CLINICAL ONCOLOGY, GRUNE AND STRATTON, NEW YORK, NY, US, (199810), vol. 16, no. 10, ISSN 0732-183X, pages 3412 - 3425, XP009031711 [Y] 1-7 * page 3421 - page 3423 *
 [Y]  - WOLCHOK J D ET AL, "PROPHYLACTIC RECOMBINANT EPOETIN ALFA MARKEDLY REDUCES THE NEED FOR BLOOD TRANSFUSION IN PATIENTS WITH METASTATIC MELANOMA TREATED WITH BIOCHEMOTHERAPY", CYTOKINES, CELLULAR AND MOLECULAR THERAPY, MARTIN DUNITZ PUBLISHERS, LONDON, GB, (199912), vol. 5, no. 4, ISSN 1368-4736, pages 205 - 206, XP009031732 [Y] 1-7 * the whole document *
International search[A]  - PEUCKMANN V. ET AL., "Potential novel uses of thalidomide focus on palliative care", DRUGS, (200008), vol. 60, no. 2, pages 273 - 292, XP002906602

DOI:   http://dx.doi.org/10.2165/00003495-200060020-00003
 [Y]  - MAKONKAWKEYOON S. ET AL., "Thalidomide inhibits the replication of human immunodeficiency virus type 1", PROC. NATL. ACAD. SCI. USA, (199307), vol. 90, pages 5974 - 5978, XP000938703

DOI:   http://dx.doi.org/10.1073/pnas.90.13.5974
 [Y]  - MARROTT J.B. ET AL., "A double-blind placebo-controlled phase II trial of thalidomide in asymptomatic HIV-positive patients: Clinical tolerance and effect on activation markers and cytokines", AIDS RES. HUM. RETROVIRUSES, (1997), vol. 13, no. 18, pages 1625 - 1631, XP002906601
 [Y]  - REGULIER E. ET AL., "Continuous delivery of human and mouse erythropoietin in mice by genetically engineered polymer encapsulated myoblasts", GENE THERAPY, (199808), vol. 5, no. 8, pages 1014 - 1022, XP001013508

DOI:   http://dx.doi.org/10.1038/sj.gt.3300687
 [Y]  - ARRIETA O. ET AL., "Protective effect of pentoxifylline plus thalidomide against septic shock in mice", INT. J. EXP. PATH., (199902), vol. 80, no. 1, pages 11 - 16, XP002906600

DOI:   http://dx.doi.org/10.1046/j.1365-2613.1999.00085.x
 [Y]  - BLADE J. ET AL., "Treatment approaches for relapsing and refractory multiple myeloma", ACTA ONCOL., (2000), vol. 39, no. 7, pages 843 - 847, XP002906599

DOI:   http://dx.doi.org/10.1080/028418600750063604
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