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Extract from the Register of European Patents

EP About this file: EP1283722

EP1283722 - COMBINED USE OF ANTI-CYTOKINE ANTIBODIES OR ANTAGONISTS AND ANTI-CD20 FOR THE TREATMENT OF B CELL LYMPHOMA [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  26.03.2010
Database last updated on 19.10.2024
Most recent event   Tooltip26.03.2010Application deemed to be withdrawnpublished on 28.04.2010  [2010/17]
Applicant(s)For all designated states
Biogen Idec Inc.
14 Cambridge Center
Cambridge, MA 02142 / US
[2009/14]
Former [2004/51]For all designated states
Biogen Idec Inc.
5200 Research Place
San Diego, CA 92122 / US
Former [2003/08]For all designated states
Idec Pharmaceuticals Corporation
11011 Torreyana Road
San Diego, CA 92121 / US
Inventor(s)01 / HANNA, Nabil
14770 Avenida Insurgentes
Rancho Santa Fe, CA 92067 / US
 [2003/08]
Representative(s)Adams, Harvey Vaughan John, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2005/48]Adams, Harvey Vaughan John, et al
Mathys & Squire, 120 Holborn
London EC1N 2SQ / GB
Former [2003/08]Daniels, Jeffrey Nicholas, et al
Page White & Farrer 54 Doughty Street
London WC1N 2LS / GB
Application number, filing date01964666.002.04.2001
[2003/08]
WO2001US10382
Priority number, dateUS20000193467P31.03.2000         Original published format: US 193467 P
[2003/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0174388
Date:11.10.2001
Language:EN
[2001/41]
Type: A1 Application with search report 
No.:EP1283722
Date:19.02.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 11.10.2001 takes the place of the publication of the European patent application.
[2003/08]
Search report(s)International search report - published on:EP11.10.2001
ClassificationIPC:A61K39/395, A61P35/00, // (C07K16/24, 16:28), A61K39:395, A61K31:00
[2003/08]
CPC:
C07K16/244 (EP,US); A61K39/395 (KR); A61K39/39541 (EP,US);
A61K39/3955 (EP,US); A61P35/00 (EP); A61P35/02 (EP);
C07K16/24 (EP,US); A61K2039/505 (EP,US); A61K38/00 (EP,US) (-)
C-Set:
A61K39/39541, A61K2300/00 (EP,US);
A61K39/3955, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2003/08]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:KOMBINIERTE VERWENDUNG VON ANTI-ZYTOKIN-ANTIKÖRPERN ODER ANTAGONISTEN UND ANTI-CD20 ZUR BEHANDLUNG VON B-ZELL-LYMPHOMEN[2003/08]
English:COMBINED USE OF ANTI-CYTOKINE ANTIBODIES OR ANTAGONISTS AND ANTI-CD20 FOR THE TREATMENT OF B CELL LYMPHOMA[2003/08]
French:UTILISATION COMBINEE D'ANTICORPS OU D'ANTAGONISTES ANTI-CYTOKINE ET D'ANTI-CD20 POUR LE TRAITEMENT DU LYMPHOME B[2003/08]
Entry into regional phase30.10.2002National basic fee paid 
30.10.2002Designation fee(s) paid 
30.10.2002Examination fee paid 
Examination procedure26.10.2001Request for preliminary examination filed
International Preliminary Examining Authority: US
30.10.2002Examination requested  [2003/08]
22.06.2004Amendment by applicant (claims and/or description)
26.04.2006Despatch of a communication from the examining division (Time limit: M06)
06.11.2006Reply to a communication from the examining division
04.01.2007Despatch of a communication from the examining division (Time limit: M06)
16.07.2007Reply to a communication from the examining division
12.02.2008Despatch of a communication from the examining division (Time limit: M07)
02.09.2008Reply to a communication from the examining division
31.10.2009Application deemed to be withdrawn, date of legal effect  [2010/17]
08.12.2009Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2010/17]
Fees paidRenewal fee
14.04.2003Renewal fee patent year 03
15.04.2004Renewal fee patent year 04
20.04.2005Renewal fee patent year 05
26.04.2006Renewal fee patent year 06
27.04.2007Renewal fee patent year 07
25.04.2008Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.04.200909   M06   Not yet paid
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Cited inInternational search[XY]DE29512719U  (SABAT ROBERT [DE], et al) [X] 72,73 * page 2, paragraph 1 * * page 3, paragraph 5 * [Y] 1-14,18-47,50,52-56,58-71,74-86;
 [XY]WO9404180  (SCHERING CORP [US]) [X] 72,73 * abstract * * page 1, line 9 - page 2, line 9 * * claims 1-11 * [Y] 1-14,18-47,50,52-56,58-71,74-86;
 [Y]  - CZUCZMAN M S ET AL, "Treatment of patients with low-grade B-cell Lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy", JOURNAL OF CLINICAL ONCOLOGY, PHILADELPHIA, PA, US, (199901), vol. 17, no. 1, pages 268 - 276, XP000952705 [Y] 1-14,18-47,50,52-56,58-71,74-86 * abstract * * page 268, column 1, line 1 - page 269, column 2, paragraph 2 * * page 270, column 1, paragraph 3 - column 2, paragraph 3 * * page 275, column 2, paragraph 2 *
 [Y]  - DEMIDEM AICHA ET AL, "Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (1997), Database accession no. PREV199799709997, XP002176012 [Y] 29-47,50,52-56,58-71,74-86 * abstract *
    [ ] - CANCER BIOTHERAPY & RADIOPHARMACEUTICALS, (1997), vol. 12, no. 3, ISSN 1084-9785, pages 177 - 186
 [Y]  - BUSKE C ET AL, "Monoclonal antibody therapy for b cell non-Hodgkin's lymphomas: emerging concepts of a tumour-targeted strategy", EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, (1999), vol. 35, no. 4, ISSN 0959-8049, pages 549 - 557, XP001010018 [Y] 29-47,50,52-56,58-71,74-86 * abstract * * page 550, column 1, paragraph 4 - page 553, column 2, paragraph 1 * * page 555, column 1, paragraph L *

DOI:   http://dx.doi.org/10.1016/S0959-8049(98)00420-1
 [A]  - CORTES J KURZROCK R, "Interleukin-10 in non-Hodgkin's lymphoma", LEUKEMIA AND LYMPHOMA, HARWOOD ACADEMIC PUBLISHERS, CHUR, CH, (199707), vol. 26, no. 3/4, ISSN 1042-8194, pages 251 - 259, XP001020774 [A] 1-14,18-47,50,52-56,58-86 * the whole document *
Examination   - DEMIDEM A. ET AL, "ENDOGENOUS IL-10 IS A PROTECTIVE FACTOR IN DRUG RESISTANT AIDS-RELATED LYMPHOMA (ARL)", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, NEW YORK, NY, US, (19950318), vol. 36, page 323, XP001009556
    - ALAS ET AL, "Inhibition of Interleukin 10 by Rituximab Results in Down-Regulation of Bcl-2 and Sensitization of B-cell Non-Hodgkin's Lymphoma to apoptosis", CLINICAL CANCER RESEARCH, (200103), vol. 7, pages 709 - 723
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